| Friday, February 7 |
| Future Senator Mel Almada is born in Huatabampo, Mexico. |
| Wednesday, March 26 |
| Future Senator Bill Zuber is born in Middle Amana, IA. |
| Wednesday, April 9 |
| » Major-league debuts: Benny Meyer (Dodgers) |
| Thursday, April 10 |
| » Defeated Yankees (0-1), 2-1 | Griffith Stadium (1-0) | 1-0 | |
| » Starters: George McConnell vs Walter Johnson | First | -- |
| » Major-league debuts: Ralph Young (Yankees) |
| Friday, April 11 |
| » Major-league debuts: Hugh High (Tigers) |
| Saturday, April 12 |
| » Major-league debuts: Hub Leonard (Red Sox) |
| Sunday, April 13 |
| » Major-league debuts: Dwight Stone and Ernie Walker (Browns) |
| Wednesday, April 16 |
| » Major-league debuts: Ray Powell (Tigers) |
| Thursday, April 17 |
| » Defeated Yankees (1-3), 9-3 | Polo Grounds V (1-0) | 2-0 | Won 2 |
| » Starters: Bob Groom vs George McConnell | Second | ½ out |
| Friday, April 18 |
| » Defeated Yankees (1-4), 7-5 | Polo Grounds V (2-0) | 3-0 | Won 3 |
| » Starters: Tom Hughes vs Ray Fisher | First | -- |
| Saturday, April 19 |
| » Defeated Yankees (1-5), 3-0 | Polo Grounds V (3-0) | 4-0 | Won 4 |
| » Starters: Walter Johnson vs Ray Keating | First | -- |
| Monday, April 21 |
| » Defeated Yankees (1-6), 8-4 | Polo Grounds V (4-0) | 5-0 | Won 5 |
| » Starters: Joe Engel vs Russ Ford | First | -- |
| Tuesday, April 22 |
| » Lost to Red Sox (3-6), 8-3 | Griffith Stadium (1-1) | 5-1 | |
| » Starters: Dutch Leonard vs Bob Groom | Second | ½ out |
| Wednesday, April 23 |
| » Defeated Red Sox (3-7), 6-0 | Griffith Stadium (2-1) | 6-1 | |
| » Starters: Ray Collins vs Walter Johnson | First | -- |
| Thursday, April 24 |
| » Lost to Red Sox (4-7), 6-3 | Griffith Stadium (2-2) | 6-2 | |
| » Starters: Hugh Bedient vs Bob Groom | Second | ½ out |
| Friday, April 25 |
| » Defeated Red Sox (4-8), 5-4 | Griffith Stadium (3-2) | 7-2 | |
| » Starters: Buck O'Brien vs Bert Gallia | Second | ½ out |
| Saturday, April 26 |
| » Lost to Athletics (9-2), 3-2 | Shibe Park (0-1) | 7-3 | |
| » Starters: Tom Hughes vs Boardwalk Brown | Third | 1½ out |
| Wednesday, April 30 |
| » Defeated Athletics (9-3), 2-0 | Shibe Park (1-1) | 8-3 | |
| » Starters: Walter Johnson vs Eddie Plank | Second | ½ out |
| Thursday, May 1 |
| » Lost to Red Sox (7-8), 8-2 | Fenway Park (0-1) | 8-4 | |
| » Starters: Tom Hughes vs Buck O'Brien | Third | 1½ out |
| Friday, May 2 |
| » Defeated Red Sox (7-9), 5-4 | Fenway Park (1-1) | 9-4 | |
| » Starters: Bob Groom vs Dutch Leonard | Third | 1½ out |
| Saturday, May 3 |
| » Defeated Red Sox (7-10), 2-1 | Fenway Park (2-1) | 10-4 | Won 2 |
| » Starters: Joe Engel vs Hugh Bedient | Third | 1½ out |
| Monday, May 5 |
| » Defeated Red Sox (7-11), 5-3 | Fenway Park (3-1) | 11-4 | Won 3 |
| » Starters: Joe Engel vs Buck O'Brien | Second | 1½ out |
| Wednesday, May 7 |
| » Defeated White Sox (13-10), 3-2 | Comiskey Park I (1-0) | 12-4 | Won 4 |
| » Starters: Tom Hughes vs Eddie Cicotte | Second | 1½ out |
| Thursday, May 8 |
| » Lost to White Sox (14-10), 10-5 | Comiskey Park I (1-1) | 12-5 | |
| » Starters: Bob Groom vs Reb Russell | Third | 2½ out |
| Friday, May 9 |
| » Lost to White Sox (15-10), 6-1 | Comiskey Park I (1-2) | 12-6 | Lost 2 |
| » Starters: Joe Engel vs Jim Scott | Third | 2½ out |
| Saturday, May 10 |
| » Defeated White Sox (15-11), 1-0 | Comiskey Park I (2-2) | 13-6 | |
| » Starters: Walter Johnson vs Joe Benz | Third | 2½ out |
| Sunday, May 11 |
| » Lost to Browns (11-15), 7-3 | Sportsman's Park III (0-1) | 13-7 | |
| » Starters: Tom Hughes vs George Baumgardner | Third | 2½ out |
| Monday, May 12 |
| » Defeated Browns (11-16), 2-0 | Sportsman's Park III (1-1) | 14-7 | |
| » Starters: Bob Groom vs Roy Mitchell | Third | 2½ out |
| Tuesday, May 13 |
| » Lost to Browns (12-16), 7-6 | Sportsman's Park III (1-2) | 14-8 | |
| » Starters: Carl Cashion vs Earl Hamilton | Third | 3 out |
| » Major-league debuts: Joe Gedeon (Senators) |
| Wednesday, May 14 |
| » Defeated Browns (12-17), 10-5 | Sportsman's Park III (2-2) | 15-8 | |
| » Starters: Walter Johnson vs Walt Leverenz | Third | 2½ out |
| Friday, May 16 |
| » Lost to Tigers (10-19), 5-2 | Tiger Stadium (0-1) | 15-9 | |
| » Starters: Tom Hughes vs Jean Dubuc | Third | 3 out |
| Saturday, May 17 |
| » Defeated Tigers (10-20), 5-2 | Tiger Stadium (1-1) | 16-9 | |
| » Starters: Bob Groom vs Marc Hall | Third | 2 out |
| Sunday, May 18 |
| » Defeated Tigers (10-21), 2-1 | Tiger Stadium (2-1) | 17-9 | Won 2 |
| » Starters: Walter Johnson vs Carl Zamloch | Second | 2 out |
| Monday, May 19 |
| » Lost to Indians (20-11), 4-1 | League Park II (0-1) | 17-10 | |
| » Starters: Carl Cashion vs Cy Falkenberg | Third | 2 out |
| Tuesday, May 20 |
| » Lost to Indians (21-11), 10-9 | League Park II (0-2) | 17-11 | Lost 2 |
| » Starters: George Mullin vs Willie Mitchell | Third | 2 out |
| » Major-league debuts: Nick Cullop (Indians) |
| Wednesday, May 21 |
| » Defeated Indians (21-12), 5-3 | League Park II (1-2) | 18-11 | |
| » Starters: Bob Groom vs George Kahler | Third | 1½ out |
| Thursday, May 22 |
| » Lost to Indians (22-12), 5-0 | League Park II (1-3) | 18-12 | |
| » Starters: Walter Johnson vs Bill Steen | Fourth | 2½ out |
| Saturday, May 24 |
| » Lost to Athletics (21-9), 4-2 | Shibe Park (1-2) | 18-13 | Lost 2 |
| » Starters: George Mullin vs Boardwalk Brown | Fourth | 3½ out |
| Monday, May 26 |
| » Lost to Athletics (22-9), 4-0 | Shibe Park (1-3) | 18-14 | Lost 3 |
| » Starters: Bob Groom vs Byron Houck | Third | 3½ out |
| » Defeated Athletics (22-10), 9-2 | Shibe Park (2-3) | 19-14 | |
| » Starters: Walter Johnson vs John Taff | Third | 3½ out |
| Tuesday, May 27 |
| » Lost to Athletics (23-10), 8-0 | Shibe Park (2-4) | 19-15 | |
| » Starters: Joe Engel vs Eddie Plank | Fourth | 5½ out |
| » Lost to Athletics (24-10), 7-1 | Shibe Park (2-5) | 19-16 | Lost 2 |
| » Starters: Tom Hughes vs Chief Bender | Fourth | 5½ out |
| Thursday, May 29 |
| » Defeated Red Sox (15-20), 5-2 | Griffith Stadium (4-2) | 20-16 | |
| » Starters: Buck O'Brien vs George Mullin | Third | 5½ out |
| Friday, May 30 |
| » Defeated Red Sox (15-21), 4-3 | Griffith Stadium (5-2) | 21-16 | Won 2 |
| » Starters: Joe Wood vs Bob Groom | Third | 6½ out |
| » Lost to Red Sox (16-21), 1-0 | Griffith Stadium (5-3) | 21-17 | |
| » Starters: Ray Collins vs Walter Johnson | Third | 6½ out |
| Saturday, May 31 |
| » Defeated Red Sox (16-22), 5-4 | Griffith Stadium (6-3) | 22-17 | |
| » Starters: Hugh Bedient vs Tom Hughes | Third | 6½ out |
| Monday, June 2 |
| » Lost to Athletics (29-10), 9-4 | Griffith Stadium (6-4) | 22-18 | |
| » Starters: Boardwalk Brown vs George Mullin | Fourth | 8½ out |
| » Lost to Athletics (30-10), 4-3 | Griffith Stadium (6-5) | 22-19 | Lost 2 |
| » Starters: Byron Houck vs Walter Johnson | Fourth | 8½ out |
| Tuesday, June 3 |
| » Defeated Browns (19-30), 3-2 | Griffith Stadium (7-5) | 23-19 | |
| » Starters: Earl Hamilton vs Bob Groom | Third | 8½ out |
| Wednesday, June 4 |
| » Defeated Browns (19-31), 6-2 | Griffith Stadium (8-5) | 24-19 | Won 2 |
| » Starters: Carl Weilman vs Joe Engel | Third | 8½ out |
| Thursday, June 5 |
| » Lost to Browns (20-31), 12-3 | Griffith Stadium (8-6) | 24-20 | |
| » Starters: Roy Mitchell vs George Mullin | Fourth | 9½ out |
| Friday, June 6 |
| » Defeated Browns (20-32), 1-0 | Griffith Stadium (9-6) | 25-20 | |
| » Starters: Walt Leverenz vs Walter Johnson | Third | 9½ out |
| Saturday, June 7 |
| » Lost to Tigers (19-31), 11-1 | Griffith Stadium (9-7) | 25-21 | |
| » Starters: Hooks Dauss vs Bob Groom | Third | 10½ out |
| Monday, June 9 |
| » Lost to Tigers (20-31), 6-4 | Griffith Stadium (9-8) | 25-22 | Lost 2 |
| » Starters: Ed Willett vs Tom Hughes | Third | 11½ out |
| Tuesday, June 10 |
| » Defeated Tigers (20-32), 3-0 | Griffith Stadium (10-8) | 26-22 | |
| » Starters: Al Clauss vs Walter Johnson | Third | 11½ out |
| Wednesday, June 11 |
| » Lost to Tigers (21-32), 11-0 | Griffith Stadium (10-9) | 26-23 | |
| » Starters: Hooks Dauss vs Joe Engel | Fourth | 11½ out |
| Thursday, June 12 |
| » Defeated White Sox (28-25), 5-4 | Griffith Stadium (11-9) | 27-23 | |
| » Starters: Eddie Cicotte vs Bob Groom | Third | 11½ out |
| Friday, June 13 |
| » Lost to White Sox (29-25), 6-4 | Griffith Stadium (11-10) | 27-24 | |
| » Starters: Ed Walsh vs Tom Hughes | Fourth | 12½ out |
| Saturday, June 14 |
| » Defeated White Sox (29-26), 8-3 | Griffith Stadium (12-10) | 28-24 | |
| » Starters: Jim Scott vs Walter Johnson | Third | 11½ out |
| Sunday, June 15 |
| » Defeated Indians (36-18), 10-5 | League Park II (2-3) | 29-24 | Won 2 |
| » Starters: Joe Boehling vs George Kahler | Third | 11 out |
| » Major-league debuts: Dave Gregg (Indians) Merito Acosta (Senators) |
| Monday, June 16 |
| » Lost to White Sox (30-26), 4-1 | Griffith Stadium (12-11) | 29-25 | |
| » Starters: Reb Russell vs Bob Groom | Third | 12 out |
| Tuesday, June 17 |
| » Defeated Indians (36-20), 6-3 | Griffith Stadium (13-11) | 30-25 | |
| » Starters: Willie Mitchell vs George Mullin | Third | 12 out |
| Wednesday, June 18 |
| » Lost to Indians (37-20), 4-0 | Griffith Stadium (13-12) | 30-26 | |
| » Starters: Vean Gregg vs Walter Johnson | Third | 12 out |
| Thursday, June 19 |
| » Defeated Indians (37-21), 6-3 | Griffith Stadium (14-12) | 31-26 | |
| » Starters: Cy Falkenberg vs Joe Boehling | Third | 12 out |
| Friday, June 20 |
| » Lost to Yankees (16-39), 9-3 | Griffith Stadium (14-13) | 31-27 | |
| » Starters: Jack Warhop vs Bob Groom | Fifth | 12½ out |
| » Lost to Yankees (17-39), 9-3 | Griffith Stadium (14-14) | 31-28 | Lost 2 |
| » Starters: Al Schulz vs Bert Gallia | Fifth | 12½ out |
| Saturday, June 21 |
| » Defeated Yankees (17-40), 4-1 | Griffith Stadium (15-14) | 32-28 | |
| » Starters: Ray Fisher vs George Mullin | Fourth | 11 out |
| » Defeated Yankees (17-41), 6-0 | Griffith Stadium (16-14) | 33-28 | Won 2 |
| » Starters: Ray Keating vs Walter Johnson | Fourth | 11 out |
| Tuesday, June 24 |
| » Defeated Yankees (17-42), 3-0 | Griffith Stadium (17-14) | 34-28 | Won 3 |
| » Starters: George McConnell vs Joe Boehling | Third | 11 out |
| Wednesday, June 25 |
| » Lost to Athletics (44-15), 14-2 | Griffith Stadium (17-15) | 34-29 | |
| » Starters: Bullet Joe Bush vs Walter Johnson | Third | 12 out |
| Thursday, June 26 |
| » Lost to Athletics (45-15), 11-2 | Griffith Stadium (17-16) | 34-30 | Lost 2 |
| » Starters: Eddie Plank vs George Mullin | Fifth | 14 out |
| » Lost to Athletics (46-15), 10-3 | Griffith Stadium (17-17) | 34-31 | Lost 3 |
| » Starters: Boardwalk Brown vs Bob Groom | Fifth | 14 out |
| Friday, June 27 |
| » Defeated Athletics (46-16), 2-0 | Griffith Stadium (18-17) | 35-31 | |
| » Starters: Boardwalk Brown vs Walter Johnson | Fifth | 14 out |
| » Lost to Athletics (47-16), 11-5 | Griffith Stadium (18-18) | 35-32 | |
| » Starters: Byron Houck vs Tom Hughes | Fifth | 14 out |
| » Major-league debuts: Harry Harper (Senators) |
| Saturday, June 28 |
| » Defeated Athletics (47-17), 8-3 | Griffith Stadium (19-18) | 36-32 | |
| » Starters: Byron Houck vs Joe Boehling | Fifth | 13 out |
| Sunday, June 29 |
| » Major-league debuts: Wally Pipp (Tigers) |
| Monday, June 30 |
| » Defeated Red Sox (34-30), 3-1 | Fenway Park (4-1) | 37-32 | Won 2 |
| » Starters: Bob Groom vs Joe Wood | Fourth | 13 out |
| Tuesday, July 1 |
| » Defeated Red Sox (34-31), 7-4 | Fenway Park (5-1) | 38-32 | Won 3 |
| » Starters: Joe Engel vs Hugh Bedient | Fourth | 13 out |
| Wednesday, July 2 |
| » Defeated Red Sox (34-32), 5-0 | Fenway Park (6-1) | 39-32 | Won 4 |
| » Starters: Joe Boehling vs Earl Moseley | Third | 13 out |
| Thursday, July 3 |
| » Defeated Red Sox (34-33), 1-0 | Fenway Park (7-1) | 40-32 | Won 5 |
| » Starters: Walter Johnson vs Ray Collins | Third | 13 out |
| Friday, July 4 |
| » Defeated Yankees (19-50), 5-0 | Polo Grounds V (5-0) | 41-32 | Won 6 |
| » Starters: Bob Groom vs Jack Warhop | Third | 13 out |
| » Lost to Yankees (20-50), 5-2 | Polo Grounds V (5-1) | 41-33 | |
| » Starters: George Mullin vs George McConnell | Third | 13 out |
| Monday, July 7 |
| » Lost to Yankees (21-50), 5-2 | Polo Grounds V (5-2) | 41-34 | Lost 2 |
| » Starters: Joe Boehling vs Ray Fisher | Third | 13½ out |
| » Defeated Yankees (21-51), 8-1 | Polo Grounds V (6-2) | 42-34 | |
| » Starters: Joe Engel vs Al Schulz | Third | 13½ out |
| Wednesday, July 9 |
| » Lost to Tigers (31-50), 5-3 | Tiger Stadium (2-2) | 42-35 | |
| » Starters: Bob Groom vs Hooks Dauss | Third | 14 out |
| » Defeated Tigers (31-51), 9-0 | Tiger Stadium (3-2) | 43-35 | |
| » Starters: Walter Johnson vs Jean Dubuc | Third | 14 out |
| Thursday, July 10 |
| » Lost to Tigers (32-51), 4-2 | Tiger Stadium (3-3) | 43-36 | |
| » Starters: Tom Hughes vs Marc Hall | Third | 14 out |
| Friday, July 11 |
| » Defeated Tigers (32-52), 5-2 | Tiger Stadium (4-3) | 44-36 | |
| » Starters: Joe Boehling vs Ed Willett | Third | 14 out |
| Saturday, July 12 |
| » Lost to Indians (50-31), 5-4 | League Park II (2-4) | 44-37 | |
| » Starters: Bob Groom vs Vean Gregg | Third | 15 out |
| Sunday, July 13 |
| » Defeated Indians (50-32), 5-4 | League Park II (3-4) | 45-37 | |
| » Starters: Walter Johnson vs Nick Cullop | Third | 13½ out |
| Monday, July 14 |
| » Defeated Indians (50-33), 4-3 | League Park II (4-4) | 46-37 | Won 2 |
| » Starters: Bob Groom vs Cy Falkenberg | Third | 12½ out |
| Wednesday, July 16 |
| » Defeated Browns (36-54), 3-2 | Sportsman's Park III (3-2) | 47-37 | Won 3 |
| » Starters: Joe Boehling vs Walt Leverenz | Third | 12½ out |
| Thursday, July 17 |
| » Defeated Browns (36-55), 1-0 | Sportsman's Park III (4-2) | 48-37 | Won 4 |
| » Starters: Joe Engel vs Carl Weilman | Third | 11½ out |
| Friday, July 18 |
| » Defeated Browns (36-56), 5-1 | Sportsman's Park III (5-2) | 49-37 | Won 5 |
| » Starters: Bob Groom vs George Baumgardner | Third | 11½ out |
| Saturday, July 19 |
| » Lost to Browns (37-56), 4-3 | Sportsman's Park III (5-3) | 49-38 | |
| » Starters: Joe Engel vs Earl Hamilton | Third | 12 out |
| Former Senator Jiggs Donahue dies in Columbus, OH at the age of 35. |
| Sunday, July 20 |
| » Defeated White Sox (50-43), 5-1 | Comiskey Park I (3-2) | 50-38 | |
| » Starters: Joe Boehling vs Doc White | Third | 12 out |
| Monday, July 21 |
| » Defeated White Sox (50-44), 2-1 | Comiskey Park I (4-2) | 51-38 | Won 2 |
| » Starters: Walter Johnson vs Reb Russell | Third | 12 out |
| Tuesday, July 22 |
| » Lost to White Sox (51-44), 6-5 | Comiskey Park I (4-3) | 51-39 | |
| » Starters: Bob Groom vs Reb Russell | Third | 12 out |
| Wednesday, July 23 |
| » Defeated White Sox (51-45), 7-1 | Comiskey Park I (5-3) | 52-39 | |
| » Starters: Joe Boehling vs Jim Scott | Third | 12 out |
| Friday, July 25 |
| » Tied Browns, 8-8 | Griffith Stadium (19-18) | 52-39 | |
| » Starters: George Baumgardner vs Joe Engel | Third | 12½ out |
| Saturday, July 26 |
| » Defeated Browns (38-60), 6-5 | Griffith Stadium (20-18) | 53-39 | Won 2 |
| » Starters: George Baumgardner vs Bob Groom | Third | 11 out |
| » Defeated Browns (38-61), 6-0 | Griffith Stadium (21-18) | 54-39 | Won 3 |
| » Starters: Earl Hamilton vs Joe Engel | Third | 11 out |
| Monday, July 28 |
| » Lost to Browns (39-61), 4-1 | Griffith Stadium (21-19) | 54-40 | |
| » Starters: Roy Mitchell vs Joe Boehling | Third | 11½ out |
| Tuesday, July 29 |
| » Defeated Browns (39-62), 2-1 | Griffith Stadium (22-19) | 55-40 | |
| » Starters: Walt Leverenz vs Joe Engel | Third | 11½ out |
| Thursday, July 31 |
| » Lost to Tigers (41-59), 4-1 | Griffith Stadium (22-20) | 55-41 | |
| » Starters: Marc Hall vs Joe Boehling | Third | 12 out |
| Friday, August 1 |
| » Lost to Tigers (42-59), 9-3 | Griffith Stadium (22-21) | 55-42 | Lost 2 |
| » Starters: Joe Lake vs Bob Groom | Third | 12 out |
| Saturday, August 2 |
| » Defeated Tigers (42-60), 3-2 | Griffith Stadium (23-21) | 56-42 | |
| » Starters: Hooks Dauss vs Walter Johnson | Third | 12 out |
| Monday, August 4 |
| » Lost to White Sox (53-51), 5-3 | Griffith Stadium (23-22) | 56-43 | |
| » Starters: Reb Russell vs Joe Engel | Third | 13 out |
| Tuesday, August 5 |
| » Lost to White Sox (54-51), 4-2 | Griffith Stadium (23-23) | 56-44 | Lost 2 |
| » Starters: Joe Benz vs Joe Boehling | Third | 13 out |
| Wednesday, August 6 |
| » Defeated White Sox (54-52), 11-2 | Griffith Stadium (24-23) | 57-44 | |
| » Starters: Pop-boy Smith vs Walter Johnson | Third | 13 out |
| Thursday, August 7 |
| » Lost to White Sox (55-52), 11-4 | Griffith Stadium (24-24) | 57-45 | |
| » Starters: Eddie Cicotte vs Joe Engel | Third | 14 out |
| Friday, August 8 |
| » Defeated Indians (64-42), 4-3 | Griffith Stadium (25-24) | 58-45 | |
| » Starters: Nick Cullop vs Walter Johnson | Third | 13 out |
| Future Senator Cecil Travis is born in Riverdale, GA. |
| Saturday, August 9 |
| » Lost to Indians (65-42), 3-1 | Griffith Stadium (25-25) | 58-46 | |
| » Starters: Fred Blanding vs Joe Boehling | Third | 13 out |
| Sunday, August 10 |
| » Defeated Indians (65-43), 6-1 | League Park II (5-4) | 59-46 | |
| » Starters: Bob Groom vs Vean Gregg | Third | 12½ out |
| Monday, August 11 |
| » Lost to Indians (66-43), 6-1 | Griffith Stadium (25-26) | 59-47 | |
| » Starters: Willie Mitchell vs Joe Engel | Third | 13½ out |
| Thursday, August 14 |
| » Lost to Tigers (47-63), 5-4 | Tiger Stadium (4-4) | 59-48 | Lost 2 |
| » Starters: Joe Boehling vs Jean Dubuc | Third | 13 out |
| Friday, August 15 |
| » Defeated Tigers (47-64), 9-7 | Tiger Stadium (5-4) | 60-48 | |
| » Starters: Walter Johnson vs Marc Hall | Third | 13 out |
| Saturday, August 16 |
| » Defeated Tigers (47-65), 6-1 | Tiger Stadium (6-4) | 61-48 | Won 2 |
| » Starters: Bob Groom vs Hooks Dauss | Third | 12 out |
| Sunday, August 17 |
| » Lost to Tigers (48-65), 7-1 | Tiger Stadium (6-5) | 61-49 | |
| » Starters: Joe Engel vs Ed Willett | Third | 12 out |
| Monday, August 18 |
| » Defeated Indians (69-45), 6-3 | League Park II (6-4) | 62-49 | |
| » Starters: Joe Boehling vs Fred Blanding | Third | 11 out |
| Tuesday, August 19 |
| » Defeated Indians (69-46), 5-1 | League Park II (7-4) | 63-49 | Won 2 |
| » Starters: Walter Johnson vs Cy Falkenberg | Third | 11 out |
| Thursday, August 21 |
| » Defeated Browns (47-74), 2-0 | Sportsman's Park III (6-3) | 64-49 | Won 3 |
| » Starters: Bob Groom vs Walt Leverenz | Third | 11½ out |
| Friday, August 22 |
| » Lost to Browns (48-74), 3-0 | Sportsman's Park III (6-4) | 64-50 | |
| » Starters: Joe Boehling vs Roy Mitchell | Third | 12½ out |
| Saturday, August 23 |
| » Defeated Browns (48-75), 4-2 | Sportsman's Park III (7-4) | 65-50 | |
| » Starters: Joe Engel vs George Baumgardner | Third | 11½ out |
| Sunday, August 24 |
| » Defeated White Sox (64-58), 2-1 | Comiskey Park I (6-3) | 66-50 | Won 2 |
| » Starters: Walter Johnson vs Jim Scott | Third | 11½ out |
| Monday, August 25 |
| » Lost to White Sox (65-58), 5-2 | Comiskey Park I (6-4) | 66-51 | |
| » Starters: Bob Groom vs Reb Russell | Third | 12½ out |
| Tuesday, August 26 |
| » Defeated White Sox (65-59), 5-3 | Comiskey Park I (7-4) | 67-51 | |
| » Starters: Joe Boehling vs Jim Scoggins | Third | 12½ out |
| Wednesday, August 27 |
| » Major-league debuts: Rube Schauer (Giants) |
| Thursday, August 28 |
| » Lost to Red Sox (59-59), 1-0 | Fenway Park (7-2) | 67-52 | |
| » Starters: Walter Johnson vs Ray Collins | Third | 13½ out |
| Saturday, August 30 |
| » Defeated Red Sox (59-60), 4-1 | Fenway Park (8-2) | 68-52 | |
| » Starters: Joe Engel vs Hugh Bedient | Third | 11½ out |
| » Defeated Red Sox (59-61), 4-0 | Fenway Park (9-2) | 69-52 | Won 2 |
| » Starters: Bob Groom vs Dutch Leonard | Third | 11½ out |
| Monday, September 1 |
| » Lost to Athletics (82-41), 4-1 | Shibe Park (2-6) | 69-53 | |
| » Starters: Joe Boehling vs Chief Bender | Third | 13½ out |
| » Lost to Athletics (83-41), 6-5 | Shibe Park (2-7) | 69-54 | Lost 2 |
| » Starters: Walter Johnson vs Boardwalk Brown | Third | 13½ out |
| Tuesday, September 2 |
| » Defeated Athletics (83-42), 2-1 | Shibe Park (3-7) | 70-54 | |
| » Starters: Joe Engel vs Bob Shawkey | Third | 12½ out |
| Wednesday, September 3 |
| » Lost to Athletics (84-42), 4-3 | Shibe Park (3-8) | 70-55 | |
| » Starters: Bob Groom vs Boardwalk Brown | Third | 13½ out |
| Thursday, September 4 |
| » Lost to Yankees (44-80), 3-2 | Griffith Stadium (25-27) | 70-56 | Lost 2 |
| » Starters: Ray Fisher vs Bert Gallia | Third | 13 out |
| Friday, September 5 |
| » Defeated Yankees (44-81), 3-2 | Griffith Stadium (26-27) | 71-56 | |
| » Starters: Al Schulz vs Joe Boehling | Third | 11½ out |
| » Defeated Yankees (44-82), 1-0 | Griffith Stadium (27-27) | 72-56 | Won 2 |
| » Starters: Russ Ford vs Walter Johnson | Third | 11½ out |
| Saturday, September 6 |
| » Defeated Yankees (44-83), 9-1 | Griffith Stadium (28-27) | 73-56 | Won 3 |
| » Starters: Marty McHale vs Carl Cashion | Third | 11½ out |
| » Major-league debuts: Jack Bentley (Senators) Cy Pieh (Yankees) |
| Monday, September 8 |
| » Lost to Yankees (45-83), 4-0 | Griffith Stadium (28-28) | 73-57 | |
| » Starters: Ray Caldwell vs Joe Engel | Third | 12 out |
| » Major-league debuts: Slim Love and Ben Spencer (Senators) |
| Tuesday, September 9 |
| » Defeated Indians (80-53), 8-1 | Griffith Stadium (29-28) | 74-57 | |
| » Starters: Vean Gregg vs Joe Boehling | Third | 10½ out |
| » Defeated Indians (80-54), 8-2 | Griffith Stadium (30-28) | 75-57 | Won 2 |
| » Starters: Fred Blanding vs Walter Johnson | Third | 10½ out |
| » Major-league debuts: Doc Ayers (Senators) Josh Billings (Indians) |
| Wednesday, September 10 |
| » Defeated Indians (80-55), 2-1 | Griffith Stadium (31-28) | 76-57 | Won 3 |
| » Starters: Vean Gregg vs Bob Groom | Third | 9½ out |
| Thursday, September 11 |
| » Defeated Indians (80-56), 7-3 | Griffith Stadium (32-28) | 77-57 | Won 4 |
| » Starters: Bill Steen vs Joe Engel | Third | 9½ out |
| Friday, September 12 |
| » Defeated Indians (80-57), 6-1 | Griffith Stadium (33-28) | 78-57 | Won 5 |
| » Starters: Fred Blanding vs Walter Johnson | Third | 9½ out |
| Saturday, September 13 |
| » Lost to White Sox (71-68), 6-4 | Griffith Stadium (33-29) | 78-58 | |
| » Starters: Eddie Cicotte vs Joe Boehling | Third | 9½ out |
| Monday, September 15 |
| » Lost to White Sox (72-68), 5-0 | Griffith Stadium (33-30) | 78-59 | Lost 2 |
| » Starters: Reb Russell vs Bob Groom | Third | 10½ out |
| » Major-league debuts: Jim Shaw (Senators) |
| Tuesday, September 16 |
| » Defeated White Sox (72-69), 2-1 | Griffith Stadium (34-30) | 79-59 | |
| » Starters: Joe Benz vs Walter Johnson | Third | 10½ out |
| Wednesday, September 17 |
| » Lost to Tigers (61-78), 5-1 | Griffith Stadium (34-31) | 79-60 | |
| » Starters: Jean Dubuc vs Bert Gallia | Third | 12 out |
| » Lost to Tigers (62-78), 4-2 | Griffith Stadium (34-32) | 79-61 | Lost 2 |
| » Starters: Lefty Williams vs Joe Boehling | Third | 12 out |
| » Major-league debuts: Lefty Williams (Tigers) |
| Thursday, September 18 |
| » Defeated Tigers (62-79), 6-1 | Griffith Stadium (35-32) | 80-61 | |
| » Starters: Erwin Renfer vs Bob Groom | Third | 11 out |
| Friday, September 19 |
| » Defeated Tigers (62-80), 2-1 | Griffith Stadium (36-32) | 81-61 | Won 2 |
| » Starters: Ralph Comstock vs Slim Love | Third | 10½ out |
| Saturday, September 20 |
| » Defeated Browns (53-92), 6-3 | Griffith Stadium (37-32) | 82-61 | Won 3 |
| » Starters: George Baumgardner vs Joe Engel | Second | 10½ out |
| Monday, September 22 |
| » Lost to Browns (54-92), 7-5 | Griffith Stadium (37-33) | 82-62 | |
| » Starters: Walt Leverenz vs Doc Ayers | Third | 12 out |
| Tuesday, September 23 |
| » Lost to Browns (55-92), 5-3 | Griffith Stadium (37-34) | 82-63 | Lost 2 |
| » Starters: Wiley Taylor vs Bob Groom | Third | 13 out |
| Thursday, September 25 |
| » Defeated Yankees (53-89), 5-2 | Polo Grounds V (7-2) | 83-63 | |
| » Starters: Walter Johnson vs Russ Ford | Third | 12½ out |
| Friday, September 26 |
| » Defeated Yankees (53-90), 3-0 | Polo Grounds V (8-2) | 84-63 | Won 2 |
| » Starters: Joe Boehling vs Marty McHale | Third | 11½ out |
| Saturday, September 27 |
| » Defeated Yankees (53-91), 8-3 | Polo Grounds V (9-2) | 85-63 | Won 3 |
| » Starters: Bob Groom vs Ray Caldwell | Second | 10½ out |
| Monday, September 29 |
| » Defeated Athletics (95-53), 1-0 | Griffith Stadium (38-34) | 86-63 | Won 4 |
| » Starters: Weldon Wyckoff vs Walter Johnson | Second | 9½ out |
| » Major-league debuts: Wickey McAvoy (Athletics) |
| Tuesday, September 30 |
| » Defeated Athletics (95-54), 3-0 | Griffith Stadium (39-34) | 87-63 | Won 5 |
| » Starters: Charlie Boardman vs Doc Ayers | Second | 8½ out |
| Wednesday, October 1 |
| » Defeated Athletics (95-55), 1-0 | Griffith Stadium (40-34) | 88-63 | Won 6 |
| » Starters: Pat Bohen vs Jack Bentley | Second | 7½ out |
| Friday, October 3 |
| » Lost to Red Sox (79-69), 2-0 | Griffith Stadium (40-35) | 88-64 | |
| » Starters: Dutch Leonard vs Jim Shaw | Second | 7½ out |
| » Defeated Red Sox (79-70), 11-3 | Griffith Stadium (41-35) | 89-64 | |
| » Starters: Earl Moseley vs Joe Boehling | Second | 7½ out |
| » Major-league debuts: Harry Hedgpeth (Senators) |
| Saturday, October 4 |
| » Defeated Red Sox (79-71), 10-9 | Griffith Stadium (42-35) | 90-64 | Won 2 |
| » Starters: Fred Anderson vs Mutt Williams | Second | 6½ out |
| Monday, October 6 |
| Future Senator Ken Chase is born in Oneonta, NY. |
| Monday, October 13 |
| Former Senator Mike Heydon dies in Indianapolis, IN at the age of 40. |
| Saturday, October 18 |
| Future Senator Roy Cullenbine is born in Nashville, TN. |
| Tuesday, October 21 |
| Future Senator Mark Christman is born in Maplewood, MO. |
Game information provided by Retrosheet (www.retrosheet.org) |