| Tuesday, January 14 |
| Former Indian Hal O'Hagen dies in Newark, NJ at the age of 40. |
| Wednesday, March 26 |
| Future Indian Bill Zuber is born in Middle Amana, IA. |
| Wednesday, April 9 |
| » Major-league debuts: Benny Meyer (Dodgers) |
| Thursday, April 10 |
| » Major-league debuts: Ralph Young (Yankees) |
| Friday, April 11 |
| » Defeated White Sox (0-1), 3-1 | League Park II (1-0) | 1-0 | |
| » Starters: Jim Scott vs Vean Gregg | Second | ½ out |
| Saturday, April 12 |
| » Lost to White Sox (1-1), 13-3 | League Park II (1-1) | 1-1 | |
| » Starters: Joe Benz vs Willie Mitchell | Third | 1 out |
| » Major-league debuts: Nemo Leibold (Indians) |
| Sunday, April 13 |
| » Major-league debuts: Dwight Stone and Ernie Walker (Browns) |
| Monday, April 14 |
| » Lost to Tigers (1-2), 5-4 | League Park II (1-2) | 1-2 | Lost 2 |
| » Starters: Jean Dubuc vs George Kahler | Fifth | 1½ out |
| Tuesday, April 15 |
| » Defeated Tigers (1-3), 9-0 | League Park II (2-2) | 2-2 | |
| » Starters: George Boehler vs Cy Falkenberg | Fourth | 1 out |
| Wednesday, April 16 |
| » Defeated Tigers (1-4), 2-1 | League Park II (3-2) | 3-2 | Won 2 |
| » Starters: George Mullin vs Vean Gregg | Fourth | 1½ out |
| » Major-league debuts: Ray Powell (Tigers) |
| Thursday, April 17 |
| » Lost to White Sox (5-2), 2-1 | Comiskey Park I (0-1) | 3-3 | |
| » Starters: Willie Mitchell vs Jim Scott | Fourth | 1½ out |
| Friday, April 18 |
| » Defeated White Sox (5-3), 4-0 | Comiskey Park I (1-1) | 4-3 | |
| » Starters: Bill Steen vs Joe Benz | Fourth | 2 out |
| » Major-league debuts: Reb Russell (White Sox) |
| Saturday, April 19 |
| » Defeated White Sox (5-4), 9-2 | Comiskey Park I (2-1) | 5-3 | Won 2 |
| » Starters: Cy Falkenberg vs Frank Lange | Third | 2 out |
| Sunday, April 20 |
| » Defeated White Sox (5-5), 2-1 | Comiskey Park I (3-1) | 6-3 | Won 3 |
| » Starters: Vean Gregg vs Ed Walsh | Third | 2½ out |
| Monday, April 21 |
| » Defeated Browns (4-7), 8-3 | League Park II (4-2) | 7-3 | Won 4 |
| » Starters: Roy Mitchell vs Willie Mitchell | Third | 2½ out |
| Tuesday, April 22 |
| » Lost to Browns (5-7), 4-2 | League Park II (4-3) | 7-4 | |
| » Starters: Earl Hamilton vs Bill Steen | Third | 2 out |
| Wednesday, April 23 |
| » Defeated Browns (5-8), 6-2 | League Park II (5-3) | 8-4 | |
| » Starters: Carl Weilman vs Cy Falkenberg | Third | 2½ out |
| Thursday, April 24 |
| » Defeated Tigers (5-8), 5-3 | Tiger Stadium (1-0) | 9-4 | Won 2 |
| » Starters: Vean Gregg vs Jean Dubuc | Third | 2 out |
| Friday, April 25 |
| » Defeated Tigers (5-9), 3-0 | Tiger Stadium (2-0) | 10-4 | Won 3 |
| » Starters: Fred Blanding vs George Mullin | Third | 2 out |
| Wednesday, April 30 |
| » Lost to Browns (8-9), 2-0 | Sportsman's Park III (0-1) | 10-5 | |
| » Starters: Vean Gregg vs George Baumgardner | Third | 1½ out |
| Thursday, May 1 |
| » Defeated Browns (8-10), 3-1 | Sportsman's Park III (1-1) | 11-5 | |
| » Starters: Cy Falkenberg vs Carl Weilman | Second | 1½ out |
| » Major-league debuts: George Maisel (Browns) |
| Friday, May 2 |
| » Defeated Browns (8-11), 9-2 | Sportsman's Park III (2-1) | 12-5 | Won 2 |
| » Starters: Fred Blanding vs Dwight Stone | Second | 1½ out |
| Saturday, May 3 |
| » Defeated Browns (8-12), 11-8 | Sportsman's Park III (3-1) | 13-5 | Won 3 |
| » Starters: Jim Baskette vs Earl Hamilton | Second | 1½ out |
| Sunday, May 4 |
| » Lost to Browns (9-12), 4-3 | Sportsman's Park III (3-2) | 13-6 | |
| » Starters: Willie Mitchell vs George Baumgardner | Third | 2 out |
| Wednesday, May 7 |
| » Defeated Red Sox (7-12), 4-1 | League Park II (6-3) | 14-6 | |
| » Starters: Dutch Leonard vs Cy Falkenberg | Third | 1½ out |
| Thursday, May 8 |
| » Defeated Red Sox (7-13), 3-2 | League Park II (7-3) | 15-6 | Won 2 |
| » Starters: Hugh Bedient vs Vean Gregg | Second | 1½ out |
| Friday, May 9 |
| » Lost to Red Sox (8-13), 3-1 | League Park II (7-4) | 15-7 | |
| » Starters: Buck O'Brien vs Fred Blanding | Second | 1½ out |
| Saturday, May 10 |
| » Defeated Red Sox (8-14), 9-2 | League Park II (8-4) | 16-7 | |
| » Starters: Charley Hall vs Bill Steen | Second | 1½ out |
| Sunday, May 11 |
| » Defeated Yankees (5-17), 7-2 | League Park II (9-4) | 17-7 | Won 2 |
| » Starters: Al Schulz vs Cy Falkenberg | Second | 1½ out |
| Monday, May 12 |
| » Lost to Yankees (6-17), 4-3 | League Park II (9-5) | 17-8 | |
| » Starters: George McConnell vs Vean Gregg | Second | 1½ out |
| Tuesday, May 13 |
| » Lost to Yankees (7-17), 8-5 | League Park II (9-6) | 17-9 | Lost 2 |
| » Starters: Russ Ford vs Fred Blanding | Second | 2 out |
| Wednesday, May 14 |
| » Tied Yankees, 2-2 | League Park II (9-6) | 17-9 | |
| » Starters: Ray Fisher vs Bill Steen | Second | 2 out |
| Thursday, May 15 |
| » Defeated Athletics (17-6), 2-0 | League Park II (10-6) | 18-9 | |
| » Starters: Eddie Plank vs Cy Falkenberg | Second | 2 out |
| Friday, May 16 |
| » Lost to Athletics (18-6), 8-5 | League Park II (10-7) | 18-10 | |
| » Starters: Boardwalk Brown vs Vean Gregg | Second | 2 out |
| Saturday, May 17 |
| » Defeated Athletics (18-7), 7-3 | League Park II (11-7) | 19-10 | |
| » Starters: Herb Pennock vs George Kahler | Second | 2 out |
| Sunday, May 18 |
| » Lost to Athletics (19-7), 4-2 | League Park II (11-8) | 19-11 | |
| » Starters: Weldon Wyckoff vs Bill Steen | Third | 2 out |
| Monday, May 19 |
| » Defeated Senators (17-10), 4-1 | League Park II (12-8) | 20-11 | |
| » Starters: Carl Cashion vs Cy Falkenberg | Second | 2 out |
| Tuesday, May 20 |
| » Defeated Senators (17-11), 10-9 | League Park II (13-8) | 21-11 | Won 2 |
| » Starters: George Mullin vs Willie Mitchell | Second | 2 out |
| » Major-league debuts: Nick Cullop (Indians) |
| Wednesday, May 21 |
| » Lost to Senators (18-11), 5-3 | League Park II (13-9) | 21-12 | |
| » Starters: Bob Groom vs George Kahler | Second | 2½ out |
| Thursday, May 22 |
| » Defeated Senators (18-12), 5-0 | League Park II (14-9) | 22-12 | |
| » Starters: Walter Johnson vs Bill Steen | Second | 2½ out |
| Saturday, May 24 |
| » Defeated White Sox (21-15), 4-3 | Comiskey Park I (4-1) | 23-12 | Won 2 |
| » Starters: Cy Falkenberg vs Ed Walsh | Second | 2½ out |
| Sunday, May 25 |
| » Defeated White Sox (21-16), 8-1 | Comiskey Park I (5-1) | 24-12 | Won 3 |
| » Starters: Willie Mitchell vs Reb Russell | Second | 3 out |
| Wednesday, May 28 |
| » Defeated White Sox (21-17), 2-1 | League Park II (15-9) | 25-12 | Won 4 |
| » Starters: Eddie Cicotte vs George Kahler | Second | 2 out |
| » Defeated White Sox (21-18), 5-3 | League Park II (16-9) | 26-12 | Won 5 |
| » Starters: Ed Walsh vs Vean Gregg | Second | 2 out |
| Thursday, May 29 |
| » Defeated Browns (18-26), 6-3 | League Park II (17-9) | 27-12 | Won 6 |
| » Starters: Dwight Stone vs Cy Falkenberg | Second | 2 out |
| Friday, May 30 |
| » Defeated Browns (18-27), 5-4 | League Park II (18-9) | 28-12 | Won 7 |
| » Starters: Carl Weilman vs Willie Mitchell | Second | 1½ out |
| Saturday, May 31 |
| » Defeated Browns (18-28), 5-4 | League Park II (19-9) | 29-12 | Won 8 |
| » Starters: Walt Leverenz vs Bill Steen | Second | 1½ out |
| Sunday, June 1 |
| » Defeated Browns (18-29), 6-1 | League Park II (20-9) | 30-12 | Won 9 |
| » Starters: Roy Mitchell vs Vean Gregg | Second | 2½ out |
| » Lost to Browns (19-29), 9-3 | League Park II (20-10) | 30-13 | |
| » Starters: George Baumgardner vs George Kahler | Second | 2½ out |
| Tuesday, June 3 |
| » Defeated Yankees (9-31), 8-2 | Polo Grounds V (1-0) | 31-13 | |
| » Starters: Cy Falkenberg vs Ray Keating | Second | 1½ out |
| Wednesday, June 4 |
| » Defeated Yankees (9-32), 9-5 | Polo Grounds V (2-0) | 32-13 | Won 2 |
| » Starters: Fred Blanding vs Russ Ford | Second | 1½ out |
| Thursday, June 5 |
| » Defeated Yankees (9-33), 5-3 | Polo Grounds V (3-0) | 33-13 | Won 3 |
| » Starters: Bill Steen vs George McConnell | Second | 1½ out |
| Friday, June 6 |
| » Defeated Yankees (9-34), 2-1 | Polo Grounds V (4-0) | 34-13 | Won 4 |
| » Starters: George Kahler vs Ray Fisher | Second | 1½ out |
| Monday, June 9 |
| » Lost to Red Sox (21-24), 4-1 | Fenway Park (0-1) | 34-14 | |
| » Starters: Cy Falkenberg vs Hugh Bedient | Second | 3 out |
| Tuesday, June 10 |
| » Lost to Red Sox (22-24), 7-3 | Fenway Park (0-2) | 34-15 | Lost 2 |
| » Starters: Vean Gregg vs Ray Collins | Second | 4 out |
| Wednesday, June 11 |
| » Defeated Red Sox (22-25), 9-5 | Fenway Park (1-2) | 35-15 | |
| » Starters: Vean Gregg vs Joe Wood | Second | 3 out |
| Thursday, June 12 |
| » Lost to Athletics (38-11), 6-1 | Shibe Park (0-1) | 35-16 | |
| » Starters: Cy Falkenberg vs Eddie Plank | Second | 4 out |
| Friday, June 13 |
| » Lost to Athletics (39-11), 2-1 | Shibe Park (0-2) | 35-17 | Lost 2 |
| » Starters: Willie Mitchell vs Chief Bender | Second | 5 out |
| Saturday, June 14 |
| » Defeated Athletics (39-12), 3-0 | Shibe Park (1-2) | 36-17 | |
| » Starters: Vean Gregg vs Bullet Joe Bush | Second | 4 out |
| Sunday, June 15 |
| » Lost to Senators (29-24), 10-5 | League Park II (20-11) | 36-18 | |
| » Starters: Joe Boehling vs George Kahler | Second | 4½ out |
| » Major-league debuts: Dave Gregg (Indians) Merito Acosta (Senators) |
| Monday, June 16 |
| » Lost to Athletics (40-12), 3-2 | Shibe Park (1-3) | 36-19 | Lost 2 |
| » Starters: Cy Falkenberg vs Eddie Plank | Second | 5½ out |
| Tuesday, June 17 |
| » Lost to Senators (30-25), 6-3 | Griffith Stadium (0-1) | 36-20 | Lost 3 |
| » Starters: Willie Mitchell vs George Mullin | Second | 6½ out |
| Wednesday, June 18 |
| » Defeated Senators (30-26), 4-0 | Griffith Stadium (1-1) | 37-20 | |
| » Starters: Vean Gregg vs Walter Johnson | Second | 5½ out |
| Thursday, June 19 |
| » Lost to Senators (31-26), 6-3 | Griffith Stadium (1-2) | 37-21 | |
| » Starters: Cy Falkenberg vs Joe Boehling | Second | 6½ out |
| Friday, June 20 |
| » Lost to White Sox (32-28), 3-0 | League Park II (20-12) | 37-22 | Lost 2 |
| » Starters: Eddie Cicotte vs George Kahler | Second | 6½ out |
| Saturday, June 21 |
| » Defeated Tigers (24-38), 7-6 | League Park II (21-12) | 38-22 | |
| » Starters: Hooks Dauss vs Cy Falkenberg | Second | 5½ out |
| Sunday, June 22 |
| » Lost to Tigers (25-38), 7-6 | League Park II (21-13) | 38-23 | |
| » Starters: Ed Willett vs Cy Falkenberg | Second | 5½ out |
| » Defeated Tigers (25-39), 2-1 | League Park II (22-13) | 39-23 | |
| » Starters: Hooks Dauss vs Vean Gregg | Second | 5½ out |
| Tuesday, June 24 |
| » Defeated Tigers (25-40), 6-4 | Tiger Stadium (3-0) | 40-23 | Won 2 |
| » Starters: George Kahler vs Ed Willett | Second | 6 out |
| » Lost to Tigers (26-40), 6-5 | Tiger Stadium (3-1) | 40-24 | |
| » Starters: Fred Blanding vs Carl Zamloch | Second | 6 out |
| Wednesday, June 25 |
| » Lost to Tigers (27-40), 4-2 | Tiger Stadium (3-2) | 40-25 | Lost 2 |
| » Starters: Nick Cullop vs Jean Dubuc | Second | 7 out |
| Thursday, June 26 |
| » Lost to White Sox (36-31), 7-5 | Comiskey Park I (5-2) | 40-26 | Lost 3 |
| » Starters: Vean Gregg vs Ed Walsh | Second | 8½ out |
| Friday, June 27 |
| » Lost to White Sox (37-31), 3-2 | Comiskey Park I (5-3) | 40-27 | Lost 4 |
| » Starters: Cy Falkenberg vs Eddie Cicotte | Second | 9 out |
| Saturday, June 28 |
| » Defeated White Sox (37-32), 3-2 | Comiskey Park I (6-3) | 41-27 | |
| » Starters: Willie Mitchell vs Jim Scott | Second | 8 out |
| Sunday, June 29 |
| » Lost to White Sox (38-32), 2-1 | Comiskey Park I (6-4) | 41-28 | |
| » Starters: George Kahler vs Reb Russell | Second | 8½ out |
| Monday, June 30 |
| » Defeated Browns (28-46), 3-2 | Sportsman's Park III (4-2) | 42-28 | |
| » Starters: Vean Gregg vs George Baumgardner | Second | 8½ out |
| Wednesday, July 2 |
| » Lost to Browns (29-46), 2-1 | Sportsman's Park III (4-3) | 42-29 | |
| » Starters: Willie Mitchell vs Earl Hamilton | Second | 9½ out |
| » Defeated Browns (29-47), 4-1 | Sportsman's Park III (5-3) | 43-29 | |
| » Starters: Cy Falkenberg vs Dwight Stone | Second | 9½ out |
| Thursday, July 3 |
| » Defeated Tigers (29-46), 3-1 | League Park II (23-13) | 44-29 | Won 2 |
| » Starters: Hooks Dauss vs George Kahler | Second | 9½ out |
| Friday, July 4 |
| » Defeated Tigers (29-47), 4-2 | League Park II (24-13) | 45-29 | Won 3 |
| » Starters: Jean Dubuc vs Fred Blanding | Second | 8½ out |
| » Defeated Tigers (29-48), 4-2 | League Park II (25-13) | 46-29 | Won 4 |
| » Starters: Ed Willett vs Vean Gregg | Second | 8½ out |
| Saturday, July 5 |
| » Tied White Sox, 5-5 | League Park II (25-13) | 46-29 | |
| » Starters: Jim Scott vs Nick Cullop | Second | 9 out |
| Sunday, July 6 |
| » Defeated White Sox (42-35), 6-2 | League Park II (26-13) | 47-29 | Won 5 |
| » Starters: Eddie Cicotte vs Cy Falkenberg | Second | 8 out |
| » Defeated White Sox (42-36), 7-0 | League Park II (27-13) | 48-29 | Won 6 |
| » Starters: Reb Russell vs Willie Mitchell | Second | 8 out |
| Wednesday, July 9 |
| » Lost to Athletics (55-19), 5-3 | League Park II (27-14) | 48-30 | |
| » Starters: Bullet Joe Bush vs Willie Mitchell | Second | 9 out |
| Thursday, July 10 |
| » Defeated Athletics (55-20), 4-1 | League Park II (28-14) | 49-30 | |
| » Starters: Eddie Plank vs Cy Falkenberg | Second | 8 out |
| Friday, July 11 |
| » Lost to Athletics (56-20), 11-5 | League Park II (28-15) | 49-31 | |
| » Starters: Chief Bender vs George Kahler | Second | 9 out |
| » Major-league debuts: Johnny Bassler (Indians) |
| Saturday, July 12 |
| » Defeated Senators (44-37), 5-4 | League Park II (29-15) | 50-31 | |
| » Starters: Bob Groom vs Vean Gregg | Second | 9 out |
| Sunday, July 13 |
| » Lost to Senators (45-37), 5-4 | League Park II (29-16) | 50-32 | |
| » Starters: Walter Johnson vs Nick Cullop | Second | 8½ out |
| Monday, July 14 |
| » Lost to Senators (46-37), 4-3 | League Park II (29-17) | 50-33 | Lost 2 |
| » Starters: Bob Groom vs Cy Falkenberg | Second | 8½ out |
| Wednesday, July 16 |
| » Defeated Yankees (24-56), 5-0 | League Park II (30-17) | 51-33 | |
| » Starters: George McConnell vs Willie Mitchell | Second | 9 out |
| » Lost to Yankees (25-56), 4-2 | League Park II (30-18) | 51-34 | |
| » Starters: Ray Fisher vs Fred Blanding | Second | 9 out |
| Thursday, July 17 |
| » Lost to Yankees (26-56), 7-1 | League Park II (30-19) | 51-35 | Lost 2 |
| » Starters: Al Schulz vs George Kahler | Second | 9 out |
| Friday, July 18 |
| » Lost to Yankees (27-56), 5-2 | League Park II (30-20) | 51-36 | Lost 3 |
| » Starters: Russ Ford vs Vean Gregg | Second | 10 out |
| Saturday, July 19 |
| » Defeated Yankees (27-57), 2-1 | League Park II (31-20) | 52-36 | |
| » Starters: Ray Keating vs Cy Falkenberg | Second | 9½ out |
| Sunday, July 20 |
| » Lost to Red Sox (42-43), 2-1 | League Park II (31-21) | 52-37 | |
| » Starters: Ray Collins vs Willie Mitchell | Second | 10½ out |
| Monday, July 21 |
| » Defeated Red Sox (42-44), 6-1 | League Park II (32-21) | 53-37 | |
| » Starters: Earl Moseley vs Fred Blanding | Second | 10½ out |
| Tuesday, July 22 |
| » Defeated Red Sox (42-45), 8-5 | League Park II (33-21) | 54-37 | Won 2 |
| » Starters: Dutch Leonard vs Vean Gregg | Second | 9½ out |
| Wednesday, July 23 |
| » Defeated Red Sox (42-46), 5-3 | League Park II (34-21) | 55-37 | Won 3 |
| » Starters: Rube Foster vs Cy Falkenberg | Second | 9½ out |
| Friday, July 25 |
| » Defeated Yankees (28-60), 3-2 | Polo Grounds V (5-0) | 56-37 | Won 4 |
| » Starters: Willie Mitchell vs Ray Fisher | Second | 9½ out |
| Saturday, July 26 |
| » Lost to Yankees (29-60), 4-3 | Polo Grounds V (5-1) | 56-38 | |
| » Starters: Fred Blanding vs Russ Ford | Second | 9½ out |
| Tuesday, July 29 |
| » Defeated Yankees (29-61), 6-2 | Polo Grounds V (6-1) | 57-38 | |
| » Starters: George Kahler vs Al Schulz | Second | 9 out |
| » Defeated Yankees (29-62), 6-3 | Polo Grounds V (7-1) | 58-38 | Won 2 |
| » Starters: Willie Mitchell vs Ray Keating | Second | 9 out |
| Thursday, July 31 |
| » Defeated Red Sox (46-47), 5-2 | Fenway Park (2-2) | 59-38 | Won 3 |
| » Starters: Cy Falkenberg vs Hugh Bedient | Second | 8 out |
| » Defeated Red Sox (46-48), 4-2 | Fenway Park (3-2) | 60-38 | Won 4 |
| » Starters: Fred Blanding vs Earl Moseley | Second | 8 out |
| Friday, August 1 |
| » Defeated Red Sox (46-49), 6-2 | Fenway Park (4-2) | 61-38 | Won 5 |
| » Starters: Nick Cullop vs Dutch Leonard | Second | 7 out |
| Saturday, August 2 |
| » Defeated Red Sox (46-50), 5-4 | Fenway Park (5-2) | 62-38 | Won 6 |
| » Starters: Vean Gregg vs Hugh Bedient | Second | 6½ out |
| » Defeated Red Sox (46-51), 7-0 | Fenway Park (6-2) | 63-38 | Won 7 |
| » Starters: Willie Mitchell vs Rube Foster | Second | 6½ out |
| Monday, August 4 |
| » Lost to Athletics (69-30), 7-1 | Shibe Park (1-4) | 63-39 | |
| » Starters: Cy Falkenberg vs Bob Shawkey | Second | 7½ out |
| » Major-league debuts: Ernie Krueger and Billy Southworth (Indians) |
| Tuesday, August 5 |
| » Defeated Athletics (69-31), 5-0 | Shibe Park (2-4) | 64-39 | |
| » Starters: Fred Blanding vs Eddie Plank | Second | 6½ out |
| Future Indian Fabian Gaffke is born in Milwaukee, WI. |
| Wednesday, August 6 |
| » Lost to Athletics (70-31), 7-1 | Shibe Park (2-5) | 64-40 | |
| » Starters: Vean Gregg vs Bullet Joe Bush | Second | 7½ out |
| Thursday, August 7 |
| » Lost to Athletics (71-31), 7-3 | Shibe Park (2-6) | 64-41 | Lost 2 |
| » Starters: Willie Mitchell vs Chief Bender | Second | 8½ out |
| Friday, August 8 |
| » Lost to Senators (58-45), 4-3 | Griffith Stadium (1-3) | 64-42 | Lost 3 |
| » Starters: Nick Cullop vs Walter Johnson | Second | 8½ out |
| Saturday, August 9 |
| » Defeated Senators (58-46), 3-1 | Griffith Stadium (2-3) | 65-42 | |
| » Starters: Fred Blanding vs Joe Boehling | Second | 7½ out |
| Sunday, August 10 |
| » Lost to Senators (59-46), 6-1 | League Park II (34-22) | 65-43 | |
| » Starters: Bob Groom vs Vean Gregg | Second | 8 out |
| Monday, August 11 |
| » Defeated Senators (59-47), 6-1 | Griffith Stadium (3-3) | 66-43 | |
| » Starters: Willie Mitchell vs Joe Engel | Second | 8 out |
| Thursday, August 14 |
| » Defeated Athletics (72-35), 6-2 | League Park II (35-22) | 67-43 | Won 2 |
| » Starters: Eddie Plank vs Fred Blanding | Second | 6½ out |
| Friday, August 15 |
| » Lost to Athletics (73-35), 12-5 | League Park II (35-23) | 67-44 | |
| » Starters: Eddie Plank vs George Kahler | Second | 7½ out |
| Saturday, August 16 |
| » Defeated Athletics (73-36), 10-1 | League Park II (36-23) | 68-44 | |
| » Starters: Bullet Joe Bush vs Willie Mitchell | Second | 6½ out |
| Sunday, August 17 |
| » Defeated Athletics (73-37), 6-2 | League Park II (37-23) | 69-44 | Won 2 |
| » Starters: Chief Bender vs Vean Gregg | Second | 5½ out |
| Monday, August 18 |
| » Lost to Senators (62-49), 6-3 | League Park II (37-24) | 69-45 | |
| » Starters: Joe Boehling vs Fred Blanding | Second | 5½ out |
| Tuesday, August 19 |
| » Lost to Senators (63-49), 5-1 | League Park II (37-25) | 69-46 | Lost 2 |
| » Starters: Walter Johnson vs Cy Falkenberg | Second | 6½ out |
| Thursday, August 21 |
| » Lost to Red Sox (54-58), 3-2 | League Park II (37-26) | 69-47 | Lost 3 |
| » Starters: Dutch Leonard vs Lefty James | Second | 8 out |
| Friday, August 22 |
| » Lost to Red Sox (55-58), 2-1 | League Park II (37-27) | 69-48 | Lost 4 |
| » Starters: Hugh Bedient vs Vean Gregg | Second | 9 out |
| Saturday, August 23 |
| » Lost to Red Sox (56-58), 4-3 | League Park II (37-28) | 69-49 | Lost 5 |
| » Starters: Ray Collins vs Fred Blanding | Second | 9 out |
| Sunday, August 24 |
| » Defeated Yankees (40-74), 4-0 | League Park II (38-28) | 70-49 | |
| » Starters: Russ Ford vs Cy Falkenberg | Second | 9 out |
| Monday, August 25 |
| » Defeated Yankees (40-75), 6-2 | League Park II (39-28) | 71-49 | Won 2 |
| » Starters: George McConnell vs Fred Blanding | Second | 9 out |
| Former Indian Red Donahue dies in Philadelphia, PA at the age of 41. |
| Tuesday, August 26 |
| » Defeated Yankees (40-76), 3-0 | League Park II (40-28) | 72-49 | Won 3 |
| » Starters: Ray Caldwell vs Vean Gregg | Second | 9 out |
| Future Indian Hank Helf is born in Austin, TX. |
| Wednesday, August 27 |
| » Major-league debuts: Rube Schauer (Giants) |
| Friday, August 29 |
| » Defeated Browns (48-79), 3-0 | Sportsman's Park III (6-3) | 73-49 | Won 4 |
| » Starters: Cy Falkenberg vs George Baumgardner | Second | 9 out |
| Saturday, August 30 |
| » Defeated Browns (48-80), 4-0 | Sportsman's Park III (7-3) | 74-49 | Won 5 |
| » Starters: Fred Blanding vs Carl Weilman | Second | 7½ out |
| Sunday, August 31 |
| » Defeated Browns (48-81), 9-1 | Sportsman's Park III (8-3) | 75-49 | Won 6 |
| » Starters: Vean Gregg vs Roy Mitchell | Second | 7 out |
| Monday, September 1 |
| » Defeated White Sox (65-62), 6-2 | League Park II (41-28) | 76-49 | Won 7 |
| » Starters: Eddie Cicotte vs Lefty James | Second | 7 out |
| » Defeated White Sox (65-63), 7-0 | League Park II (42-28) | 77-49 | Won 8 |
| » Starters: Jim Scott vs Cy Falkenberg | Second | 7 out |
| Tuesday, September 2 |
| » Lost to White Sox (66-63), 3-1 | League Park II (42-29) | 77-50 | |
| » Starters: Jim Scott vs Bill Steen | Second | 7½ out |
| » Lost to White Sox (67-63), 9-3 | League Park II (42-30) | 77-51 | Lost 2 |
| » Starters: Joe Benz vs Fred Blanding | Second | 7½ out |
| » Major-league debuts: Larry Kopf (Indians) |
| Thursday, September 4 |
| » Lost to Tigers (57-71), 4-3 | League Park II (42-31) | 77-52 | Lost 3 |
| » Starters: Jean Dubuc vs Vean Gregg | Second | 7½ out |
| Friday, September 5 |
| » Defeated Tigers (57-72), 7-6 | League Park II (43-31) | 78-52 | |
| » Starters: Ed Willett vs Lefty James | Second | 6½ out |
| Saturday, September 6 |
| » Defeated Tigers (57-73), 3-1 | Tiger Stadium (4-2) | 79-52 | Won 2 |
| » Starters: Cy Falkenberg vs Hooks Dauss | Second | 6½ out |
| Sunday, September 7 |
| » Defeated Tigers (57-74), 6-4 | Tiger Stadium (5-2) | 80-52 | Won 3 |
| » Starters: Bill Steen vs Ralph Comstock | Second | 6 out |
| Monday, September 8 |
| » Major-league debuts: Slim Love and Ben Spencer (Senators) |
| Tuesday, September 9 |
| » Lost to Senators (74-57), 8-1 | Griffith Stadium (3-4) | 80-53 | |
| » Starters: Vean Gregg vs Joe Boehling | Second | 6½ out |
| » Lost to Senators (75-57), 8-2 | Griffith Stadium (3-5) | 80-54 | Lost 2 |
| » Starters: Fred Blanding vs Walter Johnson | Second | 6½ out |
| » Major-league debuts: Doc Ayers (Senators) Josh Billings (Indians) |
| Wednesday, September 10 |
| » Lost to Senators (76-57), 2-1 | Griffith Stadium (3-6) | 80-55 | Lost 3 |
| » Starters: Vean Gregg vs Bob Groom | Second | 6½ out |
| Thursday, September 11 |
| » Lost to Senators (77-57), 7-3 | Griffith Stadium (3-7) | 80-56 | Lost 4 |
| » Starters: Bill Steen vs Joe Engel | Second | 7½ out |
| Friday, September 12 |
| » Lost to Senators (78-57), 6-1 | Griffith Stadium (3-8) | 80-57 | Lost 5 |
| » Starters: Fred Blanding vs Walter Johnson | Second | 8½ out |
| Saturday, September 13 |
| » Defeated Athletics (87-48), 3-1 | Shibe Park (3-6) | 81-57 | |
| » Starters: Cy Falkenberg vs Chief Bender | Second | 7½ out |
| Monday, September 15 |
| » Lost to Athletics (88-48), 8-6 | Shibe Park (3-7) | 81-58 | |
| » Starters: Vean Gregg vs Bullet Joe Bush | Second | 8½ out |
| Tuesday, September 16 |
| » Lost to Athletics (89-48), 8-7 | Shibe Park (3-8) | 81-59 | Lost 2 |
| » Starters: Bill Steen vs Bob Shawkey | Second | 9½ out |
| Wednesday, September 17 |
| » Defeated Red Sox (71-65), 2-0 | Fenway Park (7-2) | 82-59 | |
| » Starters: Cy Falkenberg vs Dutch Leonard | Second | 9½ out |
| Thursday, September 18 |
| » Lost to Red Sox (72-65), 5-4 | Fenway Park (7-3) | 82-60 | |
| » Starters: Nick Cullop vs Earl Moseley | Second | 9½ out |
| Saturday, September 20 |
| » Lost to Yankees (52-87), 7-3 | Polo Grounds V (7-2) | 82-61 | Lost 2 |
| » Starters: Vean Gregg vs Ray Caldwell | Second | 10½ out |
| Monday, September 22 |
| » Defeated Yankees (52-88), 5-4 | Polo Grounds V (8-2) | 83-61 | |
| » Starters: Cy Falkenberg vs Ray Fisher | Second | 11 out |
| Tuesday, September 23 |
| » Lost to Yankees (53-88), 3-1 | Polo Grounds V (8-3) | 83-62 | |
| » Starters: Cy Falkenberg vs Ray Caldwell | Second | 12 out |
| Saturday, September 27 |
| » Lost to Tigers (63-84), 7-6 | Tiger Stadium (5-3) | 83-63 | Lost 2 |
| » Starters: Bill Steen vs Jean Dubuc | Third | 12 out |
| » Lost to Tigers (64-84), 4-3 | Tiger Stadium (5-4) | 83-64 | Lost 3 |
| » Starters: Nick Cullop vs Ed Willett | Third | 12 out |
| Sunday, September 28 |
| » Lost to White Sox (77-72), 1-0 | Comiskey Park I (6-5) | 83-65 | Lost 4 |
| » Starters: Cy Falkenberg vs Eddie Cicotte | Third | 12½ out |
| Tuesday, September 30 |
| Future Indian Nate Andrews is born in Pembroke, NC. |
| Wednesday, October 1 |
| » Defeated Tigers (64-86), 8-1 | Tiger Stadium (6-4) | 84-65 | |
| » Starters: Vean Gregg vs Ralph Comstock | Third | 10½ out |
| Saturday, October 4 |
| » Defeated Browns (56-95), 5-4 | League Park II (44-31) | 85-65 | Won 2 |
| » Starters: George Baumgardner vs Nick Cullop | Third | 9½ out |
| » Tied Browns, 0-0 | League Park II (44-31) | 85-65 | |
| » Starters: Carl Weilman vs Willie Mitchell | Third | 9½ out |
| Sunday, October 5 |
| » Lost to Browns (57-95), 9-4 | League Park II (44-32) | 85-66 | |
| » Starters: Walt Leverenz vs Fred Blanding | Third | 9½ out |
| » Defeated Browns (57-96), 4-3 | League Park II (45-32) | 86-66 | |
| » Starters: Curly Brown vs Lefty James | Third | 9½ out |
| Saturday, October 18 |
| Future Indian Roy Cullenbine is born in Nashville, TN. |
| Friday, December 26 |
| Future Indian Al Milnar is born in Cleveland, OH. |
Game information provided by Retrosheet (www.retrosheet.org) |
