| Wednesday, January 3 |
| Future Giant Cliff Melton is born in Brevard, NC. |
| Friday, February 16 |
| Future Giant Ray Harrell is born in Petrolia, TX. |
| Saturday, March 2 |
| Future Giant Ace Adams is born in Willows, CA. Future Giant Bennie Warren is born in Elk City, OK. |
| Friday, March 8 |
| Future Giant Ray Mueller is born in Pittsburg, KS. |
| Thursday, April 11 |
| » Defeated Dodgers (0-1), 18-3 | Washington Park III (1-0) | 1-0 | |
| » Starters: Rube Marquard vs Nap Rucker | First | -- |
| Friday, April 12 |
| » Lost to Dodgers (1-1), 4-2 | Washington Park III (1-1) | 1-1 | |
| » Starters: Jeff Tesreau vs Elmer Knetzer | Third | 1 out |
| » Major-league debuts: Heinie Groh and Jeff Tesreau (Giants) |
| Saturday, April 13 |
| » Lost to Dodgers (2-1), 5-2 | Washington Park III (1-2) | 1-2 | Lost 2 |
| » Starters: Red Ames vs Nap Rucker | Third | 1½ out |
| Monday, April 15 |
| » Lost to Braves (3-1), 3-0 | South End Grounds III (0-1) | 1-3 | Lost 3 |
| » Starters: Christy Mathewson vs Hub Perdue | Fourth | 3 out |
| Tuesday, April 16 |
| » Defeated Braves (3-2), 8-2 | South End Grounds III (1-1) | 2-3 | |
| » Starters: Rube Marquard vs Lefty Tyler | Third | 2 out |
| Wednesday, April 17 |
| » Defeated Braves (3-3), 4-1 | South End Grounds III (2-1) | 3-3 | Won 2 |
| » Starters: Hooks Wiltse vs Buster Brown | Third | 1½ out |
| Friday, April 19 |
| » Defeated Dodgers (2-4), 6-2 | Polo Grounds V (1-0) | 4-3 | Won 3 |
| » Starters: Nap Rucker vs Christy Mathewson | Third | 1 out |
| Saturday, April 20 |
| » Defeated Dodgers (2-5), 4-3 | Polo Grounds V (2-0) | 5-3 | Won 4 |
| » Starters: Eddie Stack vs Jeff Tesreau | Second | 1 out |
| Wednesday, April 24 |
| » Defeated Phillies (4-4), 11-4 | Baker Bowl (1-0) | 6-3 | Won 5 |
| » Starters: Rube Marquard vs Pete Alexander | Second | 1 out |
| » Major-league debuts: Bill Brinker (Phillies) |
| Thursday, April 25 |
| » Defeated Phillies (4-5), 3-1 | Baker Bowl (2-0) | 7-3 | Won 6 |
| » Starters: Christy Mathewson vs Tom Seaton | Second | 1 out |
| » Major-league debuts: Gene Steinbrenner (Phillies) |
| Friday, April 26 |
| » Defeated Braves (6-6), 7-3 | Polo Grounds V (3-0) | 8-3 | Won 7 |
| » Starters: Ed Donnelly vs Doc Crandall | Second | ½ out |
| Wednesday, May 1 |
| » Defeated Phillies (4-7), 11-4 | Polo Grounds V (4-0) | 9-3 | Won 8 |
| » Starters: Tom Seaton vs Rube Marquard | Second | 1 out |
| Thursday, May 2 |
| » Defeated Phillies (4-8), 6-4 | Polo Grounds V (5-0) | 10-3 | Won 9 |
| » Starters: Earl Moore vs Jeff Tesreau | Second | 1 out |
| Friday, May 3 |
| » Lost to Phillies (5-8), 8-6 | Polo Grounds V (5-1) | 10-4 | |
| » Starters: Pete Alexander vs Red Ames | Second | 1½ out |
| Saturday, May 4 |
| » Defeated Phillies (5-9), 4-3 | Polo Grounds V (6-1) | 11-4 | |
| » Starters: Cliff Curtis vs Christy Mathewson | Second | 1½ out |
| Monday, May 6 |
| » Defeated Cardinals (5-13), 6-1 | Robison Field (1-0) | 12-4 | Won 2 |
| » Starters: Red Ames vs Slim Sallee | Second | 1½ out |
| Tuesday, May 7 |
| » Defeated Cardinals (5-14), 6-2 | Robison Field (2-0) | 13-4 | Won 3 |
| » Starters: Rube Marquard vs Bill Steele | Second | ½ out |
| Wednesday, May 8 |
| » Defeated Cardinals (5-15), 11-8 | Robison Field (3-0) | 14-4 | Won 4 |
| » Starters: Jeff Tesreau vs Bob Harmon | Second | ½ out |
| Thursday, May 9 |
| » Defeated Cardinals (5-16), 8-3 | Robison Field (4-0) | 15-4 | Won 5 |
| » Starters: Christy Mathewson vs Gene Woodburn | First | -- |
| Friday, May 10 |
| » Defeated Cubs (11-11), 4-0 | West Side Grounds (1-0) | 16-4 | Won 6 |
| » Starters: Red Ames vs Larry Cheney | First | -- |
| Saturday, May 11 |
| » Defeated Cubs (11-12), 10-3 | West Side Grounds (2-0) | 17-4 | Won 7 |
| » Starters: Rube Marquard vs Lew Richie | First | -- |
| Monday, May 13 |
| » Tied Cubs, 4-4 | West Side Grounds (2-0) | 17-4 | |
| » Starters: Jeff Tesreau vs Jimmy Lavender | First | -- |
| Wednesday, May 15 |
| » Defeated Pirates (9-12), 4-3 | Forbes Field (1-0) | 18-4 | Won 8 |
| » Starters: Red Ames vs Howie Camnitz | First | -- |
| Thursday, May 16 |
| » Defeated Pirates (9-13), 4-1 | Forbes Field (2-0) | 19-4 | Won 9 |
| » Starters: Rube Marquard vs Marty O'Toole | First | -- |
| Saturday, May 18 |
| » Lost to Reds (21-6), 4-3 | Crosley Field (0-1) | 19-5 | |
| » Starters: Christy Mathewson vs Rube Benton | First | -- |
| Sunday, May 19 |
| » Lost to Reds (22-6), 4-3 | Crosley Field (0-2) | 19-6 | Lost 2 |
| » Starters: Red Ames vs George Suggs | Second | 1½ out |
| Monday, May 20 |
| » Defeated Reds (22-7), 3-0 | Crosley Field (1-2) | 20-6 | |
| » Starters: Rube Marquard vs Art Fromme | First | -- |
| Tuesday, May 21 |
| » Defeated Reds (22-8), 6-3 | Crosley Field (2-2) | 21-6 | Won 2 |
| » Starters: Jeff Tesreau vs Bobby Keefe | First | -- |
| Wednesday, May 22 |
| » Defeated Reds (22-9), 6-1 | Crosley Field (3-2) | 22-6 | Won 3 |
| » Starters: Christy Mathewson vs Rube Benton | First | -- |
| Thursday, May 23 |
| Future Giant Augie Galan is born in Berkeley, CA. |
| Friday, May 24 |
| » Defeated Dodgers (9-19), 6-3 | Washington Park III (2-2) | 23-6 | Won 4 |
| » Starters: Rube Marquard vs Pat Ragan | First | -- |
| Saturday, May 25 |
| » Defeated Dodgers (9-20), 11-2 | Washington Park III (3-2) | 24-6 | Won 5 |
| » Starters: Hooks Wiltse vs Eddie Stack | First | -- |
| Monday, May 27 |
| » Defeated Dodgers (9-21), 6-2 | Washington Park III (4-2) | 25-6 | Won 6 |
| » Starters: Red Ames vs Elmer Knetzer | First | -- |
| Tuesday, May 28 |
| » Defeated Dodgers (9-22), 5-4 | Washington Park III (5-2) | 26-6 | Won 7 |
| » Starters: Christy Mathewson vs Pat Ragan | First | -- |
| Thursday, May 30 |
| » Defeated Phillies (14-18), 7-1 | Baker Bowl (3-0) | 27-6 | Won 8 |
| » Starters: Rube Marquard vs Tom Seaton | First | -- |
| » Defeated Phillies (14-19), 6-1 | Baker Bowl (4-0) | 28-6 | Won 9 |
| » Starters: Doc Crandall vs George Chalmers | First | -- |
| Friday, May 31 |
| » Lost to Cardinals (20-22), 5-1 | Polo Grounds V (6-2) | 28-7 | |
| » Starters: Joe Willis vs Hooks Wiltse | First | -- |
| Saturday, June 1 |
| » Defeated Cardinals (20-23), 13-4 | Polo Grounds V (7-2) | 29-7 | |
| » Starters: Bill Steele vs Christy Mathewson | First | -- |
| Monday, June 3 |
| » Defeated Cardinals (20-24), 8-3 | Polo Grounds V (8-2) | 30-7 | Won 2 |
| » Starters: Slim Sallee vs Rube Marquard | First | -- |
| Tuesday, June 4 |
| » Defeated Cardinals (20-25), 14-9 | Polo Grounds V (9-2) | 31-7 | Won 3 |
| » Starters: Joe Willis vs Red Ames | First | -- |
| Wednesday, June 5 |
| » Defeated Reds (26-18), 22-10 | Polo Grounds V (10-2) | 32-7 | Won 4 |
| » Starters: Art Fromme vs Doc Crandall | First | -- |
| » Major-league debuts: Dave Robertson (Giants) |
| Friday, June 7 |
| » Defeated Reds (26-19), 7-6 | Polo Grounds V (11-2) | 33-7 | Won 5 |
| » Starters: George Suggs vs Christy Mathewson | First | -- |
| Saturday, June 8 |
| » Defeated Reds (26-20), 6-2 | Polo Grounds V (12-2) | 34-7 | Won 6 |
| » Starters: Rube Benton vs Rube Marquard | First | -- |
| Monday, June 10 |
| » Lost to Cubs (25-18), 9-8 | Polo Grounds V (12-3) | 34-8 | |
| » Starters: Lew Richie vs Hooks Wiltse | First | -- |
| Tuesday, June 11 |
| » Defeated Cubs (25-19), 8-3 | Polo Grounds V (13-3) | 35-8 | |
| » Starters: Jimmy Lavender vs Red Ames | First | -- |
| Wednesday, June 12 |
| » Defeated Cubs (25-20), 3-2 | Polo Grounds V (14-3) | 36-8 | Won 2 |
| » Starters: Lew Richie vs Rube Marquard | First | -- |
| Thursday, June 13 |
| » Defeated Cubs (25-21), 3-2 | Polo Grounds V (15-3) | 37-8 | Won 3 |
| » Starters: Larry Cheney vs Christy Mathewson | First | -- |
| Friday, June 14 |
| » Lost to Pirates (26-20), 6-1 | Polo Grounds V (15-4) | 37-9 | |
| » Starters: Howie Camnitz vs Hooks Wiltse | First | -- |
| Saturday, June 15 |
| » Lost to Pirates (27-20), 5-4 | Polo Grounds V (15-5) | 37-10 | Lost 2 |
| » Starters: Claude Hendrix vs Doc Crandall | First | -- |
| Monday, June 17 |
| » Defeated Pirates (27-21), 5-4 | Polo Grounds V (16-5) | 38-10 | |
| » Starters: Marty O'Toole vs Rube Marquard | First | -- |
| Tuesday, June 18 |
| » Lost to Pirates (28-21), 7-2 | Polo Grounds V (16-6) | 38-11 | |
| » Starters: Howie Camnitz vs Christy Mathewson | First | -- |
| Wednesday, June 19 |
| » Defeated Braves (18-37), 6-5 | South End Grounds III (3-1) | 39-11 | |
| » Starters: Red Ames vs Otto Hess | First | -- |
| Thursday, June 20 |
| » Defeated Braves (18-38), 21-12 | South End Grounds III (4-1) | 40-11 | Won 2 |
| » Starters: Hooks Wiltse vs Buster Brown | First | -- |
| » Major-league debuts: Gil Whitehouse (Braves) Ernie Shore (Giants) |
| Friday, June 21 |
| » Defeated Braves (18-39), 5-2 | South End Grounds III (5-1) | 41-11 | Won 3 |
| » Starters: Rube Marquard vs Hub Perdue | First | -- |
| Saturday, June 22 |
| » Defeated Braves (18-40), 17-5 | South End Grounds III (6-1) | 42-11 | Won 4 |
| » Starters: Christy Mathewson vs Walt Dickson | First | -- |
| » Defeated Braves (18-41), 14-12 | South End Grounds III (7-1) | 43-11 | Won 5 |
| » Starters: Doc Crandall vs Lefty Tyler | First | -- |
| Monday, June 24 |
| » Defeated Phillies (21-29), 11-5 | Polo Grounds V (17-6) | 44-11 | Won 6 |
| » Starters: George Chalmers vs Jeff Tesreau | First | -- |
| Tuesday, June 25 |
| » Defeated Phillies (21-30), 2-1 | Polo Grounds V (18-6) | 45-11 | Won 7 |
| » Starters: Pete Alexander vs Rube Marquard | First | -- |
| Wednesday, June 26 |
| » Defeated Phillies (21-31), 3-2 | Polo Grounds V (19-6) | 46-11 | Won 8 |
| » Starters: Toots Shultz vs Red Ames | First | -- |
| Thursday, June 27 |
| » Defeated Phillies (21-32), 4-3 | Polo Grounds V (20-6) | 47-11 | Won 9 |
| » Starters: Ad Brennan vs Doc Crandall | First | -- |
| Friday, June 28 |
| » Defeated Braves (20-44), 10-3 | Polo Grounds V (21-6) | 48-11 | Won 10 |
| » Starters: Ed Donnelly vs Christy Mathewson | First | -- |
| » Defeated Braves (20-45), 12-3 | Polo Grounds V (22-6) | 49-11 | Won 11 |
| » Starters: Otto Hess vs Hooks Wiltse | First | -- |
| Saturday, June 29 |
| » Defeated Braves (20-46), 8-6 | Polo Grounds V (23-6) | 50-11 | Won 12 |
| » Starters: Buster Brown vs Rube Marquard | First | -- |
| Sunday, June 30 |
| Future Giant Johnny Hudson is born in Bryan, TX. |
| Monday, July 1 |
| » Defeated Braves (20-47), 9-6 | Polo Grounds V (24-6) | 51-11 | Won 13 |
| » Starters: Lefty Tyler vs Jeff Tesreau | First | -- |
| Tuesday, July 2 |
| » Defeated Braves (20-48), 7-3 | Polo Grounds V (25-6) | 52-11 | Won 14 |
| » Starters: Walt Dickson vs Doc Crandall | First | -- |
| Wednesday, July 3 |
| » Defeated Dodgers (25-39), 2-1 | Polo Grounds V (26-6) | 53-11 | Won 15 |
| » Starters: Nap Rucker vs Rube Marquard | First | -- |
| » Defeated Dodgers (25-40), 10-9 | Polo Grounds V (27-6) | 54-11 | Won 16 |
| » Starters: Elmer Knetzer vs Red Ames | First | -- |
| Thursday, July 4 |
| » Lost to Dodgers (26-40), 10-4 | Polo Grounds V (27-7) | 54-12 | |
| » Starters: Earl Yingling vs Christy Mathewson | First | -- |
| » Lost to Dodgers (27-40), 5-2 | Polo Grounds V (27-8) | 54-13 | Lost 2 |
| » Starters: Eddie Stack vs Hooks Wiltse | First | -- |
| Friday, July 5 |
| » Defeated Dodgers (27-41), 6-1 | Polo Grounds V (28-8) | 55-13 | |
| » Starters: Cy Barger vs Christy Mathewson | First | -- |
| Saturday, July 6 |
| » Defeated Dodgers (27-42), 5-3 | Washington Park III (6-2) | 56-13 | Won 2 |
| » Starters: Red Ames vs Nap Rucker | First | -- |
| Monday, July 8 |
| » Lost to Cubs (41-27), 7-2 | West Side Grounds (2-1) | 56-14 | |
| » Starters: Rube Marquard vs Jimmy Lavender | First | -- |
| Tuesday, July 9 |
| » Defeated Cubs (41-28), 5-2 | West Side Grounds (3-1) | 57-14 | |
| » Starters: Christy Mathewson vs Mordecai Brown | First | -- |
| Wednesday, July 10 |
| » Lost to Cubs (42-28), 3-0 | West Side Grounds (3-2) | 57-15 | |
| » Starters: Red Ames vs Lew Richie | First | -- |
| Thursday, July 11 |
| » Lost to Cubs (43-28), 11-7 | West Side Grounds (3-3) | 57-16 | Lost 2 |
| » Starters: Hooks Wiltse vs Jimmy Lavender | First | -- |
| Saturday, July 13 |
| » Defeated Cardinals (31-49), 7-2 | Robison Field (5-0) | 58-16 | |
| » Starters: Christy Mathewson vs Joe Willis | First | -- |
| Sunday, July 14 |
| » Lost to Cardinals (32-49), 3-2 | Robison Field (5-1) | 58-17 | |
| » Starters: Hooks Wiltse vs Bob Harmon | First | -- |
| » Lost to Cardinals (33-49), 4-2 | Robison Field (5-2) | 58-18 | Lost 2 |
| » Starters: Rube Marquard vs Rube Geyer | First | -- |
| Monday, July 15 |
| » Lost to Cardinals (34-49), 10-6 | Robison Field (5-3) | 58-19 | Lost 3 |
| » Starters: Red Ames vs Slim Sallee | First | -- |
| Tuesday, July 16 |
| » Lost to Cubs (48-28), 3-1 | West Side Grounds (3-4) | 58-20 | Lost 4 |
| » Starters: Jeff Tesreau vs Jimmy Lavender | First | -- |
| Wednesday, July 17 |
| » Defeated Pirates (46-32), 10-2 | Forbes Field (3-0) | 59-20 | |
| » Starters: Christy Mathewson vs Howie Camnitz | First | -- |
| Friday, July 19 |
| » Defeated Pirates (46-33), 5-4 | Forbes Field (4-0) | 60-20 | Won 2 |
| » Starters: Rube Marquard vs Marty O'Toole | First | -- |
| » Lost to Pirates (47-33), 5-4 | Forbes Field (4-1) | 60-21 | |
| » Starters: Red Ames vs Claude Hendrix | First | -- |
| Saturday, July 20 |
| » Defeated Pirates (47-34), 2-1 | Forbes Field (5-1) | 61-21 | |
| » Starters: Jeff Tesreau vs Hank Robinson | First | -- |
| Sunday, July 21 |
| » Defeated Reds (44-42), 12-6 | Crosley Field (4-2) | 62-21 | Won 2 |
| » Starters: Hooks Wiltse vs Rube Benton | First | -- |
| Monday, July 22 |
| » Defeated Reds (44-43), 4-1 | Crosley Field (5-2) | 63-21 | Won 3 |
| » Starters: Christy Mathewson vs George Suggs | First | -- |
| Tuesday, July 23 |
| » Defeated Reds (44-44), 11-1 | Crosley Field (6-2) | 64-21 | Won 4 |
| » Starters: Rube Marquard vs Bert Humphries | First | -- |
| Wednesday, July 24 |
| » Defeated Reds (44-45), 8-7 | Crosley Field (7-2) | 65-21 | Won 5 |
| » Starters: Jeff Tesreau vs Art Fromme | First | -- |
| Friday, July 26 |
| » Lost to Cubs (54-33), 4-3 | Polo Grounds V (28-9) | 65-22 | |
| » Starters: Lew Richie vs Christy Mathewson | First | -- |
| Saturday, July 27 |
| » Lost to Cubs (55-33), 7-6 | Polo Grounds V (28-10) | 65-23 | Lost 2 |
| » Starters: Jimmy Lavender vs Rube Marquard | First | -- |
| Monday, July 29 |
| » Lost to Cubs (56-33), 4-3 | Polo Grounds V (28-11) | 65-24 | Lost 3 |
| » Starters: Lew Richie vs Jeff Tesreau | First | -- |
| Tuesday, July 30 |
| » Defeated Cubs (56-34), 10-4 | Polo Grounds V (29-11) | 66-24 | |
| » Starters: Jimmy Lavender vs Christy Mathewson | First | -- |
| Wednesday, July 31 |
| » Defeated Reds (45-49), 7-0 | Polo Grounds V (30-11) | 67-24 | Won 2 |
| » Starters: Art Fromme vs Red Ames | First | -- |
| Thursday, August 1 |
| » Defeated Reds (45-50), 5-4 | Polo Grounds V (31-11) | 68-24 | Won 3 |
| » Starters: Bert Humphries vs Hooks Wiltse | First | -- |
| » Defeated Reds (45-51), 7-5 | Polo Grounds V (32-11) | 69-24 | Won 4 |
| » Starters: George Suggs vs Doc Crandall | First | -- |
| Friday, August 2 |
| » Defeated Reds (45-52), 4-0 | Polo Grounds V (33-11) | 70-24 | Won 5 |
| » Starters: Rube Benton vs Jeff Tesreau | First | -- |
| Saturday, August 3 |
| » Defeated Reds (45-53), 3-2 | Polo Grounds V (34-11) | 71-24 | Won 6 |
| » Starters: Art Fromme vs Christy Mathewson | First | -- |
| Monday, August 5 |
| » Lost to Pirates (56-38), 8-4 | Polo Grounds V (34-12) | 71-25 | |
| » Starters: Claude Hendrix vs Rube Marquard | First | -- |
| Tuesday, August 6 |
| » Lost to Pirates (57-38), 7-2 | Polo Grounds V (34-13) | 71-26 | Lost 2 |
| » Starters: Howie Camnitz vs Jeff Tesreau | First | -- |
| Wednesday, August 7 |
| » Lost to Pirates (58-38), 7-2 | Polo Grounds V (34-14) | 71-27 | Lost 3 |
| » Starters: Marty O'Toole vs Christy Mathewson | First | -- |
| Thursday, August 8 |
| » Defeated Pirates (58-39), 2-1 | Polo Grounds V (35-14) | 72-27 | |
| » Starters: Claude Hendrix vs Rube Marquard | First | -- |
| Friday, August 9 |
| » Lost to Cardinals (46-58), 4-2 | Polo Grounds V (35-15) | 72-28 | |
| » Starters: Rube Geyer vs Hooks Wiltse | First | -- |
| Future Giant Tom Sunkel is born in Paris, IL. |
| Saturday, August 10 |
| » Defeated Cardinals (46-59), 6-2 | Polo Grounds V (36-15) | 73-28 | |
| » Starters: Bill Steele vs Jeff Tesreau | First | -- |
| Monday, August 12 |
| » Lost to Cardinals (47-59), 8-6 | Polo Grounds V (36-16) | 73-29 | |
| » Starters: Bob Harmon vs Red Ames | First | -- |
| Thursday, August 15 |
| » Lost to Cubs (69-36), 5-1 | West Side Grounds (3-5) | 73-30 | Lost 2 |
| » Starters: Rube Marquard vs Lew Richie | First | -- |
| Friday, August 16 |
| » Defeated Cubs (69-37), 7-4 | West Side Grounds (4-5) | 74-30 | |
| » Starters: Jeff Tesreau vs Jimmy Lavender | First | -- |
| Saturday, August 17 |
| » Lost to Cubs (70-37), 6-5 | West Side Grounds (4-6) | 74-31 | |
| » Starters: Christy Mathewson vs Lew Richie | First | -- |
| Sunday, August 18 |
| » Defeated Cardinals (50-61), 11-1 | Robison Field (6-3) | 75-31 | |
| » Starters: Rube Marquard vs Rube Geyer | First | -- |
| Monday, August 19 |
| » Defeated Cardinals (50-62), 5-2 | Robison Field (7-3) | 76-31 | Won 2 |
| » Starters: Doc Crandall vs Slim Sallee | First | -- |
| Tuesday, August 20 |
| » Defeated Cardinals (50-63), 5-1 | Robison Field (8-3) | 77-31 | Won 3 |
| » Starters: Hooks Wiltse vs Bob Harmon | First | -- |
| Wednesday, August 21 |
| » Lost to Cubs (74-38), 4-0 | West Side Grounds (4-7) | 77-32 | |
| » Starters: Jeff Tesreau vs Lew Richie | First | -- |
| Thursday, August 22 |
| » Lost to Pirates (67-44), 3-2 | Forbes Field (5-2) | 77-33 | Lost 2 |
| » Starters: Christy Mathewson vs Howie Camnitz | First | -- |
| » Defeated Pirates (67-45), 8-6 | Forbes Field (6-2) | 78-33 | |
| » Starters: Rube Marquard vs Claude Hendrix | First | -- |
| Friday, August 23 |
| » Defeated Pirates (67-46), 2-1 | Forbes Field (7-2) | 79-33 | Won 2 |
| » Starters: Red Ames vs Hank Robinson | First | -- |
| » Defeated Pirates (67-47), 3-2 | Forbes Field (8-2) | 80-33 | Won 3 |
| » Starters: Jeff Tesreau vs Marty O'Toole | First | -- |
| Saturday, August 24 |
| » Defeated Pirates (67-48), 3-2 | Forbes Field (9-2) | 81-33 | Won 4 |
| » Starters: Hooks Wiltse vs Babe Adams | First | -- |
| Sunday, August 25 |
| » Major-league debuts: Frank Snyder (Cardinals) |
| Monday, August 26 |
| » Lost to Reds (55-63), 5-0 | Crosley Field (7-3) | 81-34 | |
| » Starters: Rube Marquard vs Rube Benton | First | -- |
| Tuesday, August 27 |
| » Lost to Reds (56-63), 2-0 | Crosley Field (7-4) | 81-35 | Lost 2 |
| » Starters: Christy Mathewson vs Art Fromme | First | -- |
| Wednesday, August 28 |
| Future Giant Goody Rosen is born in Toronto, ON. |
| Thursday, August 29 |
| » Defeated Dodgers (43-76), 4-3 | Polo Grounds V (37-16) | 82-35 | |
| » Starters: Pat Ragan vs Jeff Tesreau | First | -- |
| Friday, August 30 |
| » Lost to Dodgers (44-76), 7-5 | Polo Grounds V (37-17) | 82-36 | |
| » Starters: Eddie Stack vs Hooks Wiltse | First | -- |
| Monday, September 2 |
| » Defeated Braves (37-85), 5-2 | South End Grounds III (8-1) | 83-36 | |
| » Starters: Christy Mathewson vs Hub Perdue | First | -- |
| » Defeated Braves (37-86), 6-1 | South End Grounds III (9-1) | 84-36 | Won 2 |
| » Starters: Rube Marquard vs Ed Donnelly | First | -- |
| Tuesday, September 3 |
| » Lost to Braves (38-86), 5-1 | South End Grounds III (9-2) | 84-37 | |
| » Starters: Doc Crandall vs Otto Hess | First | -- |
| Wednesday, September 4 |
| » Defeated Phillies (61-62), 5-2 | Baker Bowl (5-0) | 85-37 | |
| » Starters: Jeff Tesreau vs Earl Moore | First | -- |
| » Lost to Phillies (62-62), 4-2 | Baker Bowl (5-1) | 85-38 | |
| » Starters: Rube Marquard vs George Chalmers | First | -- |
| » Major-league debuts: Erskine Mayer (Phillies) |
| Thursday, September 5 |
| » Defeated Phillies (62-63), 8-1 | Baker Bowl (6-1) | 86-38 | |
| » Starters: Christy Mathewson vs Tom Seaton | First | -- |
| » Defeated Phillies (62-64), 4-2 | Baker Bowl (7-1) | 87-38 | Won 2 |
| » Starters: Red Ames vs Pete Alexander | First | -- |
| Friday, September 6 |
| » Defeated Phillies (62-65), 3-0 | Baker Bowl (8-1) | 88-38 | Won 3 |
| » Starters: Jeff Tesreau vs Eppa Rixey | First | -- |
| » Defeated Phillies (62-66), 9-8 | Baker Bowl (9-1) | 89-38 | Won 4 |
| » Starters: Rube Marquard vs Happy Finneran | First | -- |
| Future Giant Vince DiMaggio is born in Martinez, CA. |
| Saturday, September 7 |
| » Lost to Phillies (63-66), 5-0 | Baker Bowl (9-2) | 89-39 | |
| » Starters: Hooks Wiltse vs Tom Seaton | First | -- |
| Former Giant Bugs Raymond dies in Chicago, IL at the age of 31. |
| Monday, September 9 |
| » Defeated Dodgers (49-80), 2-1 | Polo Grounds V (38-17) | 90-39 | |
| » Starters: Nap Rucker vs Jeff Tesreau | First | -- |
| » Defeated Dodgers (49-81), 7-2 | Polo Grounds V (39-17) | 91-39 | Won 2 |
| » Starters: Pat Ragan vs Christy Mathewson | First | -- |
| Tuesday, September 10 |
| » Defeated Cardinals (55-77), 4-3 | Polo Grounds V (40-17) | 92-39 | Won 3 |
| » Starters: Slim Sallee vs Rube Marquard | First | -- |
| Thursday, September 12 |
| » Lost to Cardinals (56-77), 4-2 | Polo Grounds V (40-18) | 92-40 | |
| » Starters: Bob Harmon vs Christy Mathewson | First | -- |
| » Defeated Cardinals (56-78), 4-1 | Polo Grounds V (41-18) | 93-40 | |
| » Starters: Rube Geyer vs Jeff Tesreau | First | -- |
| Friday, September 13 |
| » Defeated Cardinals (56-79), 3-2 | Polo Grounds V (42-18) | 94-40 | Won 2 |
| » Starters: Slim Sallee vs Rube Marquard | First | -- |
| Saturday, September 14 |
| » Defeated Cubs (83-51), 5-0 | Polo Grounds V (43-18) | 95-40 | Won 3 |
| » Starters: Lew Richie vs Jeff Tesreau | First | -- |
| Monday, September 16 |
| » Lost to Cubs (84-51), 4-3 | Polo Grounds V (43-19) | 95-41 | |
| » Starters: Jimmy Lavender vs Christy Mathewson | First | -- |
| Tuesday, September 17 |
| » Lost to Cubs (85-51), 5-3 | Polo Grounds V (43-20) | 95-42 | Lost 2 |
| » Starters: Larry Cheney vs Rube Marquard | First | -- |
| Thursday, September 19 |
| » Lost to Reds (71-69), 3-1 | Polo Grounds V (43-21) | 95-43 | Lost 3 |
| » Starters: George Suggs vs Jeff Tesreau | First | -- |
| » Tied Reds, 2-2 | Polo Grounds V (43-21) | 95-43 | |
| » Starters: Art Fromme vs Christy Mathewson | First | -- |
| Friday, September 20 |
| » Lost to Reds (72-69), 4-2 | Polo Grounds V (43-22) | 95-44 | Lost 4 |
| » Starters: Rube Benton vs Rube Marquard | First | -- |
| » Defeated Reds (72-70), 4-1 | Polo Grounds V (44-22) | 96-44 | |
| » Starters: Frank Harter vs Red Ames | First | -- |
| Saturday, September 21 |
| » Defeated Pirates (86-56), 2-1 | Polo Grounds V (45-22) | 97-44 | Won 2 |
| » Starters: Howie Camnitz vs Jeff Tesreau | First | -- |
| Monday, September 23 |
| » Major-league debuts: Ted Cather (Cardinals) |
| Thursday, September 26 |
| » Defeated Braves (47-97), 8-3 | Polo Grounds V (46-22) | 98-44 | Won 3 |
| » Starters: Hub Perdue vs Christy Mathewson | First | -- |
| » Defeated Braves (47-98), 4-0 | Polo Grounds V (47-22) | 99-44 | Won 4 |
| » Starters: Lefty Tyler vs Al Demaree | First | -- |
| » Major-league debuts: Al Demaree (Giants) |
| Friday, September 27 |
| » Defeated Braves (47-99), 7-6 | Polo Grounds V (48-22) | 100-44 | Won 5 |
| » Starters: Walt Dickson vs LaRue Kirby | First | -- |
| Saturday, September 28 |
| » Lost to Braves (48-99), 2-1 | Polo Grounds V (48-23) | 100-45 | |
| » Starters: Otto Hess vs Jeff Tesreau | First | -- |
| » Tied Braves, 6-6 | Polo Grounds V (48-23) | 100-45 | |
| » Starters: Ed Donnelly vs Ted Goulait | First | -- |
| » Major-league debuts: Mike Gonzales Joe Schultz and Sr. (Braves) |
| Sunday, September 29 |
| Future Giant Glen Stewart is born in Tullahoma, TN. |
| Monday, September 30 |
| » Defeated Phillies (70-77), 4-2 | Polo Grounds V (49-23) | 101-45 | |
| » Starters: Pete Alexander vs King Bader | First | -- |
| » Major-league debuts: Lore Bader (Giants) |
| Tuesday, October 1 |
| » Lost to Phillies (71-77), 9-2 | Polo Grounds V (49-24) | 101-46 | |
| » Starters: George Chalmers vs Rube Marquard | First | -- |
| Wednesday, October 2 |
| » Lost to Phillies (72-77), 2-1 | Polo Grounds V (49-25) | 101-47 | Lost 2 |
| » Starters: Tom Seaton vs Red Ames | First | -- |
| Thursday, October 3 |
| » Defeated Dodgers (57-94), 4-3 | Washington Park III (7-2) | 102-47 | |
| » Starters: Al Demaree vs Nap Rucker | First | -- |
| Friday, October 4 |
| » Lost to Dodgers (58-94), 8-3 | Washington Park III (7-3) | 102-48 | |
| » Starters: Rube Marquard vs Cliff Curtis | First | -- |
| Saturday, October 5 |
| » Defeated Dodgers (58-95), 1-0 | Washington Park III (8-3) | 103-48 | |
| » Starters: Jeff Tesreau vs Pat Ragan | First | -- |
| Wednesday, November 13 |
| Future Giant Alex Kampouris is born in Sacramento, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |
