| Sunday, February 2 |
| Future Senator Wes Ferrell is born in Greensboro, NC. |
| Tuesday, February 25 |
| Future Senator Al Hollingsworth is born in St. Louis, MO. |
| Thursday, March 19 |
| Future Senator Gee Walker is born in Gulfport, MS. |
| Tuesday, April 14 |
| » Lost to Red Sox (1-0), 3-1 | Huntington Ave Baseball Grounds (0-1) | 0-1 | |
| » Starters: Charlie Smith vs Cy Young | Second | 1 out |
| » Major-league debuts: Jerry Freeman (Senators) |
| Thursday, April 16 |
| » Lost to Red Sox (2-0), 3-1 | Huntington Ave Baseball Grounds (0-2) | 0-2 | Lost 2 |
| » Starters: Tom Hughes vs Cy Morgan | Third | 2 out |
| Friday, April 17 |
| » Defeated Red Sox (2-1), 2-1 | Huntington Ave Baseball Grounds (1-2) | 1-2 | |
| » Starters: Cy Falkenberg vs Tex Pruiett | Third | 2 out |
| » Major-league debuts: Amby McConnell (Red Sox) |
| Saturday, April 18 |
| » Lost to Yankees (3-1), 6-5 | Hilltop Park (0-1) | 1-3 | |
| » Starters: Bill Burns vs Doc Newton | Fourth | 2 out |
| » Major-league debuts: Bill Burns (Senators) |
| Sunday, April 19 |
| Future Senator Babe Phelps is born in Odenton, MD. |
| Monday, April 20 |
| » Lost to Yankees (4-1), 4-3 | Hilltop Park (0-2) | 1-4 | Lost 2 |
| » Starters: Hank Gehring vs Slow Joe Doyle | Seventh | 3 out |
| Tuesday, April 21 |
| » Lost to Yankees (5-1), 16-13 | Hilltop Park (0-3) | 1-5 | Lost 3 |
| » Starters: Casey Patten vs Joe Lake | Seventh | 4 out |
| » Major-league debuts: Joe Lake (Yankees) |
| Wednesday, April 22 |
| » Lost to Red Sox (5-3), 5-3 | American League Park II (0-1) | 1-6 | Lost 4 |
| » Starters: George Winter vs Charlie Smith | Seventh | 4½ out |
| Thursday, April 23 |
| » Defeated Red Sox (5-4), 6-4 | American League Park II (1-1) | 2-6 | |
| » Starters: Fred Burchell vs Bill Burns | Seventh | 4 out |
| Friday, April 24 |
| » Lost to Red Sox (6-4), 7-0 | American League Park II (1-2) | 2-7 | |
| » Starters: Cy Young vs Cy Falkenberg | Eighth | 4½ out |
| Saturday, April 25 |
| » Defeated Red Sox (6-5), 3-1 | American League Park II (2-2) | 3-7 | |
| » Starters: Cy Morgan vs Burt Keeley | Seventh | 3½ out |
| Monday, April 27 |
| » Lost to Athletics (7-5), 2-1 | Columbia Park (0-1) | 3-8 | |
| » Starters: Tom Hughes vs Rube Vickers | Sixth | 4 out |
| Tuesday, April 28 |
| » Defeated Athletics (7-6), 6-4 | Columbia Park (1-1) | 4-8 | |
| » Starters: Charlie Smith vs Eddie Plank | Sixth | 4 out |
| Wednesday, April 29 |
| » Lost to Athletics (8-6), 3-2 | Columbia Park (1-2) | 4-9 | |
| » Starters: Eli Cates vs Jimmy Dygert | Fifth | 4½ out |
| Thursday, April 30 |
| » Defeated Athletics (8-7), 2-1 | Columbia Park (2-2) | 5-9 | |
| » Starters: Tom Hughes vs Nick Carter | Fifth | 3½ out |
| Friday, May 1 |
| » Lost to Yankees (9-5), 9-4 | American League Park II (2-3) | 5-10 | |
| » Starters: Doc Newton vs Casey Patten | Sixth | 4½ out |
| Saturday, May 2 |
| » Defeated Yankees (9-6), 6-3 | American League Park II (3-3) | 6-10 | |
| » Starters: Fred Glade vs Bill Burns | Seventh | 4 out |
| Monday, May 4 |
| » Lost to Yankees (10-6), 11-5 | American League Park II (3-4) | 6-11 | |
| » Starters: Slow Joe Doyle vs Charlie Smith | Eighth | 4½ out |
| Friday, May 8 |
| » Defeated Athletics (12-8), 3-2 | American League Park II (4-4) | 7-11 | |
| » Starters: Chief Bender vs Tom Hughes | Seventh | 4 out |
| Saturday, May 9 |
| » Defeated Athletics (12-9), 6-2 | American League Park II (5-4) | 8-11 | Won 2 |
| » Starters: Nick Carter vs Bill Burns | Sixth | 4 out |
| Monday, May 11 |
| » Lost to Athletics (13-9), 7-2 | American League Park II (5-5) | 8-12 | |
| » Starters: Biff Schlitzer vs Eli Cates | Seventh | 5 out |
| Tuesday, May 12 |
| » Lost to Browns (12-11), 6-3 | American League Park II (5-6) | 8-13 | Lost 2 |
| » Starters: Jack Powell vs Charlie Smith | Seventh | 5 out |
| Wednesday, May 13 |
| » Lost to Browns (13-11), 2-1 | American League Park II (5-7) | 8-14 | Lost 3 |
| » Starters: Bill Grahame vs Bill Burns | Seventh | 6 out |
| Thursday, May 14 |
| » Defeated Browns (13-12), 4-0 | American League Park II (6-7) | 9-14 | |
| » Starters: Rube Waddell vs Tom Hughes | Seventh | 6 out |
| Saturday, May 16 |
| » Lost to White Sox (12-12), 5-0 | American League Park II (6-8) | 9-15 | |
| » Starters: Doc White vs Bill Burns | Seventh | 7 out |
| Monday, May 18 |
| » Defeated White Sox (12-13), 5-1 | American League Park II (7-8) | 10-15 | |
| » Starters: Ed Walsh vs Tom Hughes | Seventh | 6 out |
| Tuesday, May 19 |
| » Lost to White Sox (13-13), 2-0 | American League Park II (7-9) | 10-16 | |
| » Starters: Doc White vs Charlie Smith | Seventh | 7 out |
| Thursday, May 21 |
| » Defeated Tigers (12-14), 1-0 | American League Park II (8-9) | 11-16 | |
| » Starters: Ed Siever vs Bill Burns | Seventh | 6 out |
| Friday, May 22 |
| » Lost to Tigers (13-14), 4-1 | American League Park II (8-10) | 11-17 | |
| » Starters: Ed Summers vs Casey Patten | Seventh | 6½ out |
| Saturday, May 23 |
| » Lost to Tigers (14-14), 3-2 | American League Park II (8-11) | 11-18 | Lost 2 |
| » Starters: Ed Killian vs Tom Hughes | Sixth | 7½ out |
| Monday, May 25 |
| » Lost to Tigers (15-14), 1-0 | American League Park II (8-12) | 11-19 | Lost 3 |
| » Starters: Ed Siever vs Bill Burns | Seventh | 7½ out |
| Tuesday, May 26 |
| » Defeated Indians (18-13), 3-2 | American League Park II (9-12) | 12-19 | |
| » Starters: Addie Joss vs Charlie Smith | Eighth | 6½ out |
| Wednesday, May 27 |
| » Defeated Indians (18-14), 3-2 | American League Park II (10-12) | 13-19 | Won 2 |
| » Starters: Heinie Berger vs Tom Hughes | Eighth | 5½ out |
| Thursday, May 28 |
| » Defeated Indians (18-15), 8-2 | American League Park II (11-12) | 14-19 | Won 3 |
| » Starters: Bill Lattimore vs Cy Falkenberg | Seventh | 4½ out |
| Friday, May 29 |
| » Defeated Red Sox (14-22), 6-1 | Huntington Ave Baseball Grounds (2-2) | 15-19 | Won 4 |
| » Starters: Eli Cates vs Cy Morgan | Seventh | 3½ out |
| » Defeated Red Sox (14-23), 7-5 | Huntington Ave Baseball Grounds (3-2) | 16-19 | Won 5 |
| » Starters: Burt Keeley vs Fred Burchell | Seventh | 3½ out |
| » Major-league debuts: Pat Donahue (Red Sox) |
| Saturday, May 30 |
| » Lost to Red Sox (15-23), 6-0 | Huntington Ave Baseball Grounds (3-3) | 16-20 | |
| » Starters: Bill Burns vs Cy Young | Fifth | 3½ out |
| » Defeated Red Sox (15-24), 7-4 | Huntington Ave Baseball Grounds (4-3) | 17-20 | |
| » Starters: Cy Falkenberg vs Jesse Tannehill | Fifth | 3½ out |
| Monday, June 1 |
| » Lost to Athletics (21-18), 6-1 | Columbia Park (2-3) | 17-21 | |
| » Starters: Charlie Smith vs Eddie Plank | Seventh | 4½ out |
| Tuesday, June 2 |
| » Defeated Athletics (21-19), 5-2 | Columbia Park (3-3) | 18-21 | |
| » Starters: Tom Hughes vs Jimmy Dygert | Sixth | 3½ out |
| Wednesday, June 3 |
| » Lost to Athletics (22-19), 11-5 | Columbia Park (3-4) | 18-22 | |
| » Starters: Cy Falkenberg vs Chief Bender | Fifth | 3½ out |
| Friday, June 5 |
| » Lost to White Sox (20-20), 2-1 | South Side Park III (0-1) | 18-23 | Lost 2 |
| » Starters: Bill Burns vs Doc White | Fifth | 5 out |
| Saturday, June 6 |
| » Lost to White Sox (21-20), 5-4 | South Side Park III (0-2) | 18-24 | Lost 3 |
| » Starters: Jesse Tannehill vs Andy Nelson | Sixth | 5 out |
| Sunday, June 7 |
| » Lost to White Sox (22-20), 2-1 | South Side Park III (0-3) | 18-25 | Lost 4 |
| » Starters: Burt Keeley vs Nick Altrock | Eighth | 5½ out |
| Monday, June 8 |
| » Lost to White Sox (23-20), 2-1 | South Side Park III (0-4) | 18-26 | Lost 5 |
| » Starters: Bill Burns vs Doc White | Seventh | 5½ out |
| Tuesday, June 9 |
| » Lost to Browns (25-21), 4-3 | Sportsman's Park II (0-1) | 18-27 | Lost 6 |
| » Starters: Tom Hughes vs Bill Grahame | Seventh | 6½ out |
| Wednesday, June 10 |
| » Lost to Browns (26-21), 4-2 | Sportsman's Park II (0-2) | 18-28 | Lost 7 |
| » Starters: Eli Cates vs Bill Bailey | Seventh | 7½ out |
| Thursday, June 11 |
| » Lost to Browns (27-21), 6-3 | Sportsman's Park II (0-3) | 18-29 | Lost 8 |
| » Starters: Walter Johnson vs Jack Powell | Eighth | 8½ out |
| Friday, June 12 |
| » Lost to Browns (28-21), 7-5 | Sportsman's Park II (0-4) | 18-30 | Lost 9 |
| » Starters: Charlie Smith vs Rube Waddell | Eighth | 9½ out |
| Saturday, June 13 |
| » Lost to Indians (28-22), 1-0 | League Park I (0-1) | 18-31 | Lost 10 |
| » Starters: Tom Hughes vs Glenn Liebhardt | Seventh | 10½ out |
| Monday, June 15 |
| » Lost to Indians (29-22), 2-1 | League Park I (0-2) | 18-32 | Lost 11 |
| » Starters: Charlie Smith vs Heinie Berger | Eighth | 12 out |
| Tuesday, June 16 |
| » Defeated Indians (29-23), 9-3 | League Park I (1-2) | 19-32 | |
| » Starters: Burt Keeley vs Charlie Chech | Eighth | 12 out |
| Wednesday, June 17 |
| » Lost to Indians (30-23), 2-0 | League Park I (1-3) | 19-33 | |
| » Starters: Eli Cates vs Addie Joss | Eighth | 12 out |
| Thursday, June 18 |
| » Defeated Tigers (28-25), 5-0 | Bennett Park (1-0) | 20-33 | |
| » Starters: Bill Burns vs Ed Siever | Eighth | 12 out |
| Saturday, June 20 |
| » Lost to Tigers (29-25), 4-2 | Bennett Park (1-1) | 20-34 | |
| » Starters: Tom Hughes vs Ed Killian | Seventh | 13½ out |
| Sunday, June 21 |
| » Lost to Tigers (30-25), 5-2 | Burns Park (0-1) | 20-35 | Lost 2 |
| » Starters: Bill Burns vs Ed Summers | Eighth | 14½ out |
| Tuesday, June 23 |
| » Lost to Red Sox (26-34), 3-2 | Huntington Ave Baseball Grounds (4-4) | 20-36 | Lost 3 |
| » Starters: Walter Johnson vs Eddie Cicotte | Seventh | 14 out |
| Wednesday, June 24 |
| » Defeated Red Sox (26-35), 8-2 | Huntington Ave Baseball Grounds (5-4) | 21-36 | |
| » Starters: Charlie Smith vs George Winter | Seventh | 13 out |
| Thursday, June 25 |
| » Lost to Red Sox (27-35), 2-1 | Huntington Ave Baseball Grounds (5-5) | 21-37 | |
| » Starters: Eli Cates vs Cy Young | Eighth | 14 out |
| » Major-league debuts: Larry Gardner (Red Sox) |
| Friday, June 26 |
| » Defeated Red Sox (27-36), 8-0 | Huntington Ave Baseball Grounds (6-5) | 22-37 | |
| » Starters: Cy Falkenberg vs Tex Pruiett | Eighth | 14 out |
| Saturday, June 27 |
| » Lost to Athletics (29-31), 6-0 | Columbia Park (3-5) | 22-38 | |
| » Starters: Tom Hughes vs Jimmy Dygert | Eighth | 14 out |
| Monday, June 29 |
| » Lost to Athletics (30-31), 4-0 | Columbia Park (3-6) | 22-39 | Lost 2 |
| » Starters: Walter Johnson vs Rube Vickers | Eighth | 15 out |
| Tuesday, June 30 |
| » Lost to Athletics (31-31), 3-1 | Columbia Park (3-7) | 22-40 | Lost 3 |
| » Starters: Bill Burns vs Jack Coombs | Eighth | 15 out |
| Wednesday, July 1 |
| » Lost to Athletics (32-31), 2-0 | Columbia Park (3-8) | 22-41 | Lost 4 |
| » Starters: Tom Hughes vs Jimmy Dygert | Eighth | 15½ out |
| Thursday, July 2 |
| » Defeated Yankees (26-38), 4-3 | American League Park II (12-12) | 23-41 | |
| » Starters: Al Orth vs Jesse Tannehill | Eighth | 14 out |
| » Defeated Yankees (26-39), 5-3 | American League Park II (13-12) | 24-41 | Won 2 |
| » Starters: Bill Hogg vs Cy Falkenberg | Eighth | 14 out |
| Friday, July 3 |
| » Defeated Yankees (26-40), 7-4 | American League Park II (14-12) | 25-41 | Won 3 |
| » Starters: Joe Lake vs Charlie Smith | Eighth | 13½ out |
| Saturday, July 4 |
| » Lost to Yankees (27-40), 5-1 | American League Park II (14-13) | 25-42 | |
| » Starters: Rube Manning vs Burt Keeley | Eighth | 13½ out |
| » Defeated Yankees (27-41), 6-2 | American League Park II (15-13) | 26-42 | |
| » Starters: Joe Lake vs Walter Johnson | Eighth | 13½ out |
| Tuesday, July 7 |
| » Lost to White Sox (39-32), 1-0 | American League Park II (15-14) | 26-43 | |
| » Starters: Doc White vs Bill Burns | Eighth | 15½ out |
| » Lost to White Sox (40-32), 7-4 | American League Park II (15-15) | 26-44 | Lost 2 |
| » Starters: Nick Altrock vs Bill Burns | Eighth | 15½ out |
| Wednesday, July 8 |
| » Defeated White Sox (40-33), 7-1 | American League Park II (16-15) | 27-44 | |
| » Starters: Moxie Manuel vs Jesse Tannehill | Sixth | 14½ out |
| Thursday, July 9 |
| » Lost to White Sox (41-33), 5-3 | American League Park II (16-16) | 27-45 | |
| » Starters: Doc White vs Walter Johnson | Sixth | 15½ out |
| Friday, July 10 |
| » Tied White Sox, 2-2 | American League Park II (16-16) | 27-45 | |
| » Starters: Nick Altrock vs Bill Burns | Sixth | 16 out |
| Saturday, July 11 |
| » Defeated Browns (44-31), 4-2 | American League Park II (17-16) | 28-45 | |
| » Starters: Bill Dinneen vs Tom Hughes | Sixth | 15 out |
| Sunday, July 12 |
| Future Senator Allen Benson is born in Hurley, SD. |
| Monday, July 13 |
| » Lost to Browns (45-31), 3-2 | American League Park II (17-17) | 28-46 | |
| » Starters: Bill Grahame vs Walter Johnson | Eighth | 17 out |
| » Lost to Browns (46-31), 4-2 | American League Park II (17-18) | 28-47 | Lost 2 |
| » Starters: Jack Powell vs Charlie Smith | Eighth | 17 out |
| Tuesday, July 14 |
| » Defeated Browns (46-32), 7-4 | American League Park II (18-18) | 29-47 | |
| » Starters: Rube Waddell vs Eli Cates | Sixth | 16 out |
| Wednesday, July 15 |
| » Defeated Browns (46-33), 3-2 | American League Park II (19-18) | 30-47 | Won 2 |
| » Starters: Bill Bailey vs Bill Burns | Seventh | 16 out |
| Future Senator Jake Powell is born in Silver Spring, MD. |
| Thursday, July 16 |
| » Defeated Indians (44-35), 6-1 | American League Park II (20-18) | 31-47 | Won 3 |
| » Starters: Glenn Liebhardt vs Tom Hughes | Seventh | 15 out |
| Friday, July 17 |
| » Lost to Indians (45-35), 3-1 | American League Park II (20-19) | 31-48 | |
| » Starters: Addie Joss vs Walter Johnson | Seventh | 16 out |
| Saturday, July 18 |
| » Defeated Indians (45-36), 3-1 | American League Park II (21-19) | 32-48 | |
| » Starters: Bob Rhoads vs Charlie Smith | Seventh | 15 out |
| Monday, July 20 |
| » Defeated Indians (45-37), 5-3 | American League Park II (22-19) | 33-48 | Won 2 |
| » Starters: Jake Thielman vs Cy Falkenberg | Seventh | 15 out |
| Tuesday, July 21 |
| » Lost to Tigers (50-34), 4-1 | American League Park II (22-20) | 33-49 | |
| » Starters: Ed Killian vs Bill Burns | Seventh | 16 out |
| Wednesday, July 22 |
| » Lost to Tigers (51-34), 6-0 | American League Park II (22-21) | 33-50 | Lost 2 |
| » Starters: George Mullin vs Tom Hughes | Seventh | 17 out |
| Thursday, July 23 |
| » Lost to Tigers (52-34), 4-2 | American League Park II (22-22) | 33-51 | Lost 3 |
| » Starters: Ed Willett vs Walter Johnson | Seventh | 18 out |
| Saturday, July 25 |
| » Lost to Browns (51-37), 5-2 | Sportsman's Park II (0-5) | 33-52 | Lost 4 |
| » Starters: Charlie Smith vs Rube Waddell | Seventh | 19½ out |
| Sunday, July 26 |
| » Lost to Browns (52-37), 8-3 | Sportsman's Park II (0-6) | 33-53 | Lost 5 |
| » Starters: Walter Johnson vs Bill Bailey | Seventh | 20½ out |
| Monday, July 27 |
| » Lost to Browns (53-37), 6-0 | Sportsman's Park II (0-7) | 33-54 | Lost 6 |
| » Starters: Tom Hughes vs Jack Powell | Seventh | 21½ out |
| Tuesday, July 28 |
| » Defeated Browns (53-38), 2-1 | Sportsman's Park II (1-7) | 34-54 | |
| » Starters: Walter Johnson vs Bill Dinneen | Seventh | 21 out |
| Thursday, July 30 |
| » Defeated White Sox (51-41), 5-4 | South Side Park III (1-4) | 35-54 | Won 2 |
| » Starters: Jesse Tannehill vs Doc White | Seventh | 21 out |
| Friday, July 31 |
| » Lost to White Sox (52-41), 4-1 | South Side Park III (1-5) | 35-55 | |
| » Starters: Charlie Smith vs Frank Smith | Seventh | 21 out |
| Saturday, August 1 |
| » Defeated White Sox (52-42), 5-3 | South Side Park III (2-5) | 36-55 | |
| » Starters: Walter Johnson vs Ed Walsh | Seventh | 21 out |
| Sunday, August 2 |
| » Lost to White Sox (53-42), 2-1 | South Side Park III (2-6) | 36-56 | |
| » Starters: Burt Keeley vs Frank Smith | Seventh | 21 out |
| Tuesday, August 4 |
| » Lost to Indians (52-43), 7-5 | League Park I (1-4) | 36-57 | Lost 2 |
| » Starters: Tom Hughes vs Glenn Liebhardt | Seventh | 22 out |
| Wednesday, August 5 |
| » Lost to Indians (53-43), 12-1 | League Park I (1-5) | 36-58 | Lost 3 |
| » Starters: Eli Cates vs Heinie Berger | Seventh | 23 out |
| Thursday, August 6 |
| » Lost to Indians (54-43), 6-1 | League Park I (1-6) | 36-59 | Lost 4 |
| » Starters: Walter Johnson vs Cy Falkenberg | Seventh | 23½ out |
| Friday, August 7 |
| » Defeated Indians (54-44), 2-1 | League Park I (2-6) | 37-59 | |
| » Starters: Charlie Smith vs Addie Joss | Seventh | 22½ out |
| Saturday, August 8 |
| » Lost to Tigers (61-37), 18-1 | Bennett Park (1-2) | 37-60 | |
| » Starters: Burt Keeley vs Ed Willett | Seventh | 23½ out |
| Sunday, August 9 |
| » Lost to Tigers (62-37), 5-2 | Burns Park (0-2) | 37-61 | Lost 2 |
| » Starters: Tom Hughes vs Ed Killian | Seventh | 24½ out |
| Monday, August 10 |
| » Defeated Tigers (62-38), 3-2 | Bennett Park (2-2) | 38-61 | |
| » Starters: Walter Johnson vs George Mullin | Seventh | 23½ out |
| Future Senator Bill Trotter is born in Cisne, IL. |
| Tuesday, August 11 |
| » Defeated Tigers (62-39), 3-2 | Bennett Park (3-2) | 39-61 | Won 2 |
| » Starters: Charlie Smith vs Bill Donovan | Seventh | 22½ out |
| Friday, August 14 |
| » Defeated White Sox (58-46), 1-0 | American League Park II (23-22) | 40-61 | Won 3 |
| » Starters: Doc White vs Walter Johnson | Seventh | 22 out |
| » Defeated White Sox (58-47), 3-2 | American League Park II (24-22) | 41-61 | Won 4 |
| » Starters: Frank Smith vs Tom Hughes | Seventh | 22 out |
| Saturday, August 15 |
| » Lost to White Sox (59-47), 5-3 | American League Park II (24-23) | 41-62 | |
| » Starters: Ed Walsh vs Charlie Smith | Seventh | 22 out |
| Monday, August 17 |
| » Tied White Sox, 4-4 | American League Park II (24-23) | 41-62 | |
| » Starters: Doc White vs Walter Johnson | Seventh | 22½ out |
| Tuesday, August 18 |
| » Tied Browns, 3-3 | American League Park II (24-23) | 41-62 | |
| » Starters: Bill Bailey vs Eli Cates | Seventh | 23 out |
| Wednesday, August 19 |
| » Lost to Browns (62-44), 4-2 | American League Park II (24-24) | 41-63 | Lost 2 |
| » Starters: Rube Waddell vs Charlie Smith | Seventh | 22½ out |
| » Defeated Browns (62-45), 4-1 | American League Park II (25-24) | 42-63 | |
| » Starters: Jack Powell vs Tom Hughes | Seventh | 22½ out |
| Thursday, August 20 |
| » Defeated Browns (62-46), 2-0 | American League Park II (26-24) | 43-63 | Won 2 |
| » Starters: Bill Bailey vs Burt Keeley | Seventh | 21½ out |
| Friday, August 21 |
| » Defeated Tigers (65-43), 3-1 | American League Park II (27-24) | 44-63 | Won 3 |
| » Starters: Ed Willett vs Walter Johnson | Seventh | 20½ out |
| Saturday, August 22 |
| » Lost to Tigers (66-43), 6-4 | American League Park II (27-25) | 44-64 | |
| » Starters: Ed Summers vs Tom Hughes | Seventh | 21½ out |
| Monday, August 24 |
| » Lost to Tigers (67-43), 1-0 | American League Park II (27-26) | 44-65 | Lost 2 |
| » Starters: Bill Donovan vs Walter Johnson | Seventh | 22½ out |
| Friday, August 28 |
| » Defeated Indians (64-50), 2-0 | American League Park II (28-26) | 45-65 | |
| » Starters: Addie Joss vs Tom Hughes | Sixth | 21½ out |
| » Defeated Indians (64-51), 8-0 | American League Park II (29-26) | 46-65 | Won 2 |
| » Starters: Glenn Liebhardt vs Walter Johnson | Sixth | 21½ out |
| Saturday, August 29 |
| » Defeated Indians (64-52), 4-2 | American League Park II (30-26) | 47-65 | Won 3 |
| » Starters: Cy Falkenberg vs Burt Keeley | Seventh | 19½ out |
| » Defeated Indians (64-53), 3-0 | American League Park II (31-26) | 48-65 | Won 4 |
| » Starters: Heinie Berger vs Tom Hughes | Seventh | 19½ out |
| Monday, August 31 |
| » Lost to Red Sox (56-62), 7-3 | American League Park II (31-27) | 48-66 | |
| » Starters: Cy Young vs Jesse Tannehill | Seventh | 19 out |
| Tuesday, September 1 |
| » Defeated Red Sox (56-63), 6-0 | American League Park II (32-27) | 49-66 | |
| » Starters: Eddie Cicotte vs Charlie Smith | Seventh | 18 out |
| Wednesday, September 2 |
| » Defeated Red Sox (56-64), 3-2 | American League Park II (33-27) | 50-66 | Won 2 |
| » Starters: Elmer Steele vs Tom Hughes | Seventh | 18 out |
| Thursday, September 3 |
| » Lost to Red Sox (57-64), 5-2 | American League Park II (33-28) | 50-67 | |
| » Starters: Fred Burchell vs Jesse Tannehill | Seventh | 19 out |
| Friday, September 4 |
| » Defeated Yankees (40-82), 3-0 | Hilltop Park (1-3) | 51-67 | |
| » Starters: Walter Johnson vs Jack Chesbro | Seventh | 18 out |
| Saturday, September 5 |
| » Defeated Yankees (40-83), 6-0 | Hilltop Park (2-3) | 52-67 | Won 2 |
| » Starters: Walter Johnson vs Rube Manning | Seventh | 17 out |
| Monday, September 7 |
| » Defeated Yankees (40-84), 4-0 | Hilltop Park (3-3) | 53-67 | Won 3 |
| » Starters: Walter Johnson vs Jack Chesbro | Seventh | 17½ out |
| » Defeated Yankees (40-85), 9-3 | Hilltop Park (4-3) | 54-67 | Won 4 |
| » Starters: Tom Hughes vs Bill Hogg | Seventh | 17½ out |
| Tuesday, September 8 |
| » Lost to Red Sox (62-65), 3-1 | American League Park II (33-29) | 54-68 | |
| » Starters: Cy Young vs Charlie Smith | Seventh | 17½ out |
| Wednesday, September 9 |
| » Defeated Red Sox (62-66), 5-4 | American League Park II (34-29) | 55-68 | |
| » Starters: Elmer Steele vs Jesse Tannehill | Seventh | 17½ out |
| Thursday, September 10 |
| » Lost to Red Sox (63-66), 7-1 | American League Park II (34-30) | 55-69 | |
| » Starters: Fred Burchell vs Burt Keeley | Seventh | 18½ out |
| Friday, September 11 |
| » Defeated Athletics (62-65), 2-1 | American League Park II (35-30) | 56-69 | |
| » Starters: Eddie Plank vs Walter Johnson | Seventh | 18 out |
| » Lost to Athletics (63-65), 7-0 | American League Park II (35-31) | 56-70 | |
| » Starters: Jack Coombs vs Tom Hughes | Seventh | 18 out |
| Saturday, September 12 |
| » Defeated Athletics (63-66), 5-4 | American League Park II (36-31) | 57-70 | |
| » Starters: Biff Schlitzer vs Walter Johnson | Seventh | 17 out |
| Monday, September 14 |
| » Defeated Athletics (63-67), 2-1 | American League Park II (37-31) | 58-70 | Won 2 |
| » Starters: Gus Salve vs Burt Keeley | Seventh | 16 out |
| » Lost to Athletics (64-67), 5-0 | American League Park II (37-32) | 58-71 | |
| » Starters: Jack Coombs vs Burt Keeley | Seventh | 16 out |
| Tuesday, September 15 |
| » Defeated Athletics (64-68), 6-1 | American League Park II (38-32) | 59-71 | |
| » Starters: Biff Schlitzer vs Eli Cates | Seventh | 16 out |
| Thursday, September 17 |
| » Lost to White Sox (76-61), 5-0 | South Side Park III (2-7) | 59-72 | |
| » Starters: Jesse Tannehill vs Doc White | Seventh | 17½ out |
| Friday, September 18 |
| » Lost to White Sox (77-61), 1-0 | South Side Park III (2-8) | 59-73 | Lost 2 |
| » Starters: Walter Johnson vs Ed Walsh | Seventh | 17½ out |
| Saturday, September 19 |
| » Lost to White Sox (78-61), 7-2 | South Side Park III (2-9) | 59-74 | Lost 3 |
| » Starters: Roy Witherup vs Doc White | Seventh | 17½ out |
| Sunday, September 20 |
| » Lost to Browns (76-62), 2-1 | Sportsman's Park II (1-8) | 59-75 | Lost 4 |
| » Starters: Walter Johnson vs Rube Waddell | Seventh | 18½ out |
| Future Senator Zeke Bonura is born in New Orleans, LA. |
| Monday, September 21 |
| » Lost to Browns (77-62), 5-0 | Sportsman's Park II (1-9) | 59-76 | Lost 5 |
| » Starters: Burt Keeley vs Jack Powell | Seventh | 19 out |
| Wednesday, September 23 |
| » Lost to Browns (78-62), 5-4 | Sportsman's Park II (1-10) | 59-77 | Lost 6 |
| » Starters: Roy Witherup vs Harry Howell | Seventh | 20½ out |
| Thursday, September 24 |
| » Defeated Indians (83-61), 2-1 | League Park I (3-6) | 60-77 | |
| » Starters: Walter Johnson vs Glenn Liebhardt | Seventh | 19½ out |
| Friday, September 25 |
| » Defeated Indians (83-62), 6-1 | League Park I (4-6) | 61-77 | Won 2 |
| » Starters: Roy Witherup vs Charlie Chech | Seventh | 18½ out |
| Saturday, September 26 |
| » Lost to Indians (84-62), 5-4 | League Park I (4-7) | 61-78 | |
| » Starters: Tom Hughes vs Addie Joss | Seventh | 19½ out |
| Monday, September 28 |
| » Lost to Tigers (84-61), 4-1 | Bennett Park (3-3) | 61-79 | Lost 2 |
| » Starters: Tom Hughes vs Ed Killian | Seventh | 20½ out |
| Tuesday, September 29 |
| » Lost to Tigers (85-61), 4-1 | Bennett Park (3-4) | 61-80 | Lost 3 |
| » Starters: Roy Witherup vs Ed Willett | Seventh | 22½ out |
| » Lost to Tigers (86-61), 7-3 | Bennett Park (3-5) | 61-81 | Lost 4 |
| » Starters: Walter Johnson vs Ed Summers | Seventh | 22½ out |
| Wednesday, September 30 |
| » Lost to Tigers (87-61), 7-5 | Bennett Park (3-6) | 61-82 | Lost 5 |
| » Starters: Jesse Tannehill vs Bill Donovan | Seventh | 23½ out |
| Thursday, October 1 |
| » Lost to Yankees (49-97), 2-1 | Hilltop Park (4-4) | 61-83 | Lost 6 |
| » Starters: Walter Johnson vs Jack Chesbro | Seventh | 24 out |
| Friday, October 2 |
| » Defeated Yankees (49-98), 12-2 | Hilltop Park (5-4) | 62-83 | |
| » Starters: Burt Keeley vs Bill Hogg | Seventh | 24 out |
| Saturday, October 3 |
| » Lost to Yankees (50-98), 2-1 | Hilltop Park (5-5) | 62-84 | |
| » Starters: Roy Witherup vs Jack Warhop | Seventh | 25½ out |
| » Lost to Yankees (51-98), 3-2 | Hilltop Park (5-6) | 62-85 | Lost 2 |
| » Starters: Walter Johnson vs Pete Wilson | Seventh | 25½ out |
| Monday, October 5 |
| » Defeated Athletics (67-83), 3-0 | American League Park II (39-32) | 63-85 | |
| » Starters: Jack Coombs vs Charlie Smith | Seventh | 24 out |
| Tuesday, October 6 |
| » Defeated Athletics (67-84), 3-2 | American League Park II (40-32) | 64-85 | Won 2 |
| » Starters: Rube Vickers vs Tom Hughes | Seventh | 24 out |
| Future Senator Tom Padden is born in Manchester, NH. |
| Wednesday, October 7 |
| » Defeated Yankees (51-101), 1-0 | American League Park II (41-32) | 65-85 | Won 3 |
| » Starters: Jack Warhop vs Walter Johnson | Seventh | 23 out |
| » Defeated Yankees (51-102), 9-4 | American League Park II (42-32) | 66-85 | Won 4 |
| » Starters: Pete Wilson vs Roy Witherup | Seventh | 23 out |
| Thursday, October 8 |
| » Defeated Yankees (51-103), 7-5 | American League Park II (43-32) | 67-85 | Won 5 |
| » Starters: Joe Lake vs Burt Keeley | Seventh | 22½ out |
| Thursday, November 19 |
| Future Senator Harley Boss is born in Hodge, LA. |
| Thursday, November 26 |
| Future Senator Lefty Gomez is born in Rodeo, CA. |
| Friday, December 25 |
| Future Senator Ben Chapman is born in Nashville, TN. |
Game information provided by Retrosheet (www.retrosheet.org) |