| Wednesday, January 2 |
| Future Senator Red Kress is born in Columbia, CA. |
| Wednesday, January 16 |
| Future Senator Buck Jordan is born in Cooleemee, NC. |
| Sunday, January 20 |
| Future Senator Jesse Hill is born in Yates, MO. |
| Wednesday, January 23 |
| Future Senator Bobby Burke is born in Joliet, IL. |
| Wednesday, March 20 |
| Future Senator Vern Kennedy is born in Kansas City, MO. |
| Sunday, March 24 |
| Future Senator Gus Dugas is born in St. Jean De Matha, PQ. |
| Wednesday, April 10 |
| Future Senator Cliff Bolton is born in High Point, NC. |
| Thursday, April 11 |
| » Lost to Yankees (1-0), 3-2 | American League Park II (0-1) | 0-1 | |
| » Starters: Al Orth vs Tom Hughes | Second | 1 out |
| » Major-league debuts: Nig Perrine (Senators) |
| Saturday, April 13 |
| » Tied Yankees, 4-4 | American League Park II (0-1) | 0-1 | |
| » Starters: Bill Hogg vs Oscar Graham | Third | 1 out |
| Monday, April 15 |
| » Defeated Yankees (1-1), 9-4 | American League Park II (1-1) | 1-1 | |
| » Starters: Walter Clarkson vs Casey Patten | Second | ½ out |
| Tuesday, April 16 |
| » Lost to Red Sox (2-2), 4-2 | Huntington Ave Baseball Grounds (0-1) | 1-2 | |
| » Starters: Oscar Graham vs Cy Young | Fifth | 1½ out |
| Wednesday, April 17 |
| » Lost to Red Sox (3-2), 2-1 | Huntington Ave Baseball Grounds (0-2) | 1-3 | Lost 2 |
| » Starters: Charlie Smith vs Ralph Glaze | Fourth | 1½ out |
| Thursday, April 18 |
| » Defeated Red Sox (3-3), 4-0 | Huntington Ave Baseball Grounds (1-2) | 2-3 | |
| » Starters: Tom Hughes vs Frank Oberlin | Fifth | 1½ out |
| Saturday, April 20 |
| » Lost to Athletics (4-3), 6-5 | Columbia Park (0-1) | 2-4 | |
| » Starters: Frank Kitson vs Chief Bender | Fifth | 3 out |
| Monday, April 22 |
| » Lost to Athletics (5-3), 8-7 | Columbia Park (0-2) | 2-5 | Lost 2 |
| » Starters: Charlie Smith vs Eddie Plank | Seventh | 3 out |
| Wednesday, April 24 |
| » Defeated Yankees (5-3), 5-1 | Hilltop Park (1-0) | 3-5 | |
| » Starters: Casey Patten vs Slow Joe Doyle | Fourth | 2½ out |
| Thursday, April 25 |
| » Lost to Yankees (6-3), 11-2 | Hilltop Park (1-1) | 3-6 | |
| » Starters: Tom Hughes vs Al Orth | Fifth | 3½ out |
| » Major-league debuts: Lew Brockett (Yankees) |
| Friday, April 26 |
| » Lost to Yankees (7-3), 4-0 | Hilltop Park (1-2) | 3-7 | Lost 2 |
| » Starters: Oscar Graham vs Lew Brockett | Fifth | 4½ out |
| Saturday, April 27 |
| » Defeated Yankees (7-4), 3-2 | Hilltop Park (2-2) | 4-7 | |
| » Starters: Casey Patten vs Bill Hogg | Fourth | 3½ out |
| Monday, April 29 |
| » Lost to Athletics (9-4), 3-1 | American League Park II (1-2) | 4-8 | |
| » Starters: Jack Coombs vs Cy Falkenberg | Sixth | 4½ out |
| Tuesday, April 30 |
| » Lost to Athletics (10-4), 3-2 | American League Park II (1-3) | 4-9 | Lost 2 |
| » Starters: Eddie Plank vs Frank Kitson | Sixth | 5½ out |
| Thursday, May 2 |
| » Defeated Athletics (10-5), 4-1 | American League Park II (2-3) | 5-9 | |
| » Starters: Chief Bender vs Tom Hughes | Seventh | 5 out |
| Friday, May 3 |
| » Lost to Red Sox (7-10), 3-0 | American League Park II (2-4) | 5-10 | |
| » Starters: Cy Young vs Cy Falkenberg | Sixth | 5½ out |
| Saturday, May 4 |
| » Lost to Red Sox (8-10), 6-0 | American League Park II (2-5) | 5-11 | Lost 2 |
| » Starters: Ralph Glaze vs Casey Patten | Seventh | 6½ out |
| Monday, May 6 |
| » Major-league debuts: Heinie Berger (Indians) |
| Thursday, May 9 |
| » Defeated Browns (5-15), 9-4 | Sportsman's Park II (1-0) | 6-11 | |
| » Starters: Oscar Graham vs Harry Howell | Seventh | 6½ out |
| Saturday, May 11 |
| » Lost to Browns (6-15), 5-4 | Sportsman's Park II (1-1) | 6-12 | |
| » Starters: Casey Patten vs Fred Glade | Sixth | 7½ out |
| Sunday, May 12 |
| » Defeated Browns (6-16), 2-0 | Sportsman's Park II (2-1) | 7-12 | |
| » Starters: Casey Patten vs Barney Pelty | Sixth | 7½ out |
| Monday, May 13 |
| » Lost to Browns (7-16), 5-4 | Sportsman's Park II (2-2) | 7-13 | |
| » Starters: Cy Falkenberg vs Beany Jacobson | Sixth | 7½ out |
| Thursday, May 16 |
| » Lost to White Sox (18-8), 7-2 | South Side Park III (0-1) | 7-14 | Lost 2 |
| » Starters: Tom Hughes vs Frank Smith | Sixth | 8½ out |
| Friday, May 17 |
| » Defeated White Sox (18-9), 4-1 | South Side Park III (1-1) | 8-14 | |
| » Starters: Casey Patten vs Ed Walsh | Seventh | 7½ out |
| Saturday, May 18 |
| » Lost to Indians (17-11), 5-4 | League Park I (0-1) | 8-15 | |
| » Starters: Charlie Smith vs Bob Rhoads | Seventh | 8½ out |
| Monday, May 20 |
| » Defeated Indians (17-12), 8-0 | League Park I (1-1) | 9-15 | |
| » Starters: Tom Hughes vs Glenn Liebhardt | Sixth | 8 out |
| Tuesday, May 21 |
| » Lost to Indians (18-12), 4-1 | League Park I (1-2) | 9-16 | |
| » Starters: Cy Falkenberg vs Addie Joss | Seventh | 9 out |
| Wednesday, May 22 |
| » Lost to Indians (19-12), 3-2 | League Park I (1-3) | 9-17 | Lost 2 |
| » Starters: Tom Hughes vs Otto Hess | Eighth | 9½ out |
| Thursday, May 23 |
| » Lost to Tigers (17-12), 10-0 | Bennett Park (0-1) | 9-18 | Lost 3 |
| » Starters: Casey Patten vs Ed Killian | Eighth | 10 out |
| Friday, May 24 |
| » Lost to Tigers (18-12), 9-2 | Bennett Park (0-2) | 9-19 | Lost 4 |
| » Starters: Frank Kitson vs Bill Donovan | Eighth | 10½ out |
| Tuesday, May 28 |
| » Lost to Yankees (16-15), 2-1 | American League Park II (2-6) | 9-20 | Lost 5 |
| » Starters: Slow Joe Doyle vs Oscar Graham | Eighth | 12 out |
| Wednesday, May 29 |
| » Lost to Yankees (17-15), 2-0 | American League Park II (2-7) | 9-21 | Lost 6 |
| » Starters: Jack Chesbro vs Casey Patten | Eighth | 13 out |
| Thursday, May 30 |
| » Lost to Yankees (18-15), 3-1 | American League Park II (2-8) | 9-22 | Lost 7 |
| » Starters: Al Orth vs Charlie Smith | Eighth | 13 out |
| » Defeated Yankees (18-16), 9-2 | American League Park II (3-8) | 10-22 | |
| » Starters: Earl Moore vs Cy Falkenberg | Eighth | 13 out |
| Friday, May 31 |
| » Lost to Athletics (19-18), 8-2 | American League Park II (3-9) | 10-23 | |
| » Starters: Eddie Plank vs Tom Hughes | Eighth | 14 out |
| Monday, June 3 |
| » Defeated Athletics (19-19), 2-1 | American League Park II (4-9) | 11-23 | |
| » Starters: Jack Coombs vs Charlie Smith | Eighth | 14½ out |
| » Lost to Athletics (20-19), 8-4 | American League Park II (4-10) | 11-24 | |
| » Starters: Rube Waddell vs Cy Falkenberg | Eighth | 14½ out |
| Tuesday, June 4 |
| » Defeated Browns (16-25), 7-1 | American League Park II (5-10) | 12-24 | |
| » Starters: Jack Powell vs Casey Patten | Eighth | 14½ out |
| Wednesday, June 5 |
| » Lost to Browns (17-25), 10-1 | American League Park II (5-11) | 12-25 | |
| » Starters: Fred Glade vs Oscar Graham | Eighth | 15 out |
| Thursday, June 6 |
| » Lost to Browns (18-25), 5-2 | American League Park II (5-12) | 12-26 | Lost 2 |
| » Starters: Barney Pelty vs Charlie Smith | Eighth | 15 out |
| Friday, June 7 |
| » Defeated Browns (18-26), 2-1 | American League Park II (6-12) | 13-26 | |
| » Starters: Harry Howell vs Casey Patten | Seventh | 14 out |
| Saturday, June 8 |
| » Defeated White Sox (29-15), 8-2 | American League Park II (7-12) | 14-26 | Won 2 |
| » Starters: Frank Smith vs Oscar Graham | Seventh | 13 out |
| Monday, June 10 |
| » Lost to White Sox (30-15), 2-1 | American League Park II (7-13) | 14-27 | |
| » Starters: Ed Walsh vs Tom Hughes | Seventh | 14 out |
| Wednesday, June 12 |
| » Lost to White Sox (31-15), 13-1 | American League Park II (7-14) | 14-28 | Lost 2 |
| » Starters: Frank Smith vs Casey Patten | Seventh | 15 out |
| Saturday, June 15 |
| » Defeated Tigers (26-18), 10-0 | American League Park II (8-14) | 15-28 | |
| » Starters: George Mullin vs Charlie Smith | Seventh | 14½ out |
| Monday, June 17 |
| » Lost to Tigers (27-18), 5-4 | American League Park II (8-15) | 15-29 | |
| » Starters: Ed Siever vs Oscar Graham | Seventh | 14½ out |
| Tuesday, June 18 |
| » Defeated Indians (32-20), 2-1 | American League Park II (9-15) | 16-29 | |
| » Starters: Bob Rhoads vs Tom Hughes | Seventh | 13½ out |
| Wednesday, June 19 |
| » Defeated Indians (32-21), 1-0 | American League Park II (10-15) | 17-29 | Won 2 |
| » Starters: Bill Bernhard vs Charlie Smith | Seventh | 13½ out |
| Thursday, June 20 |
| » Lost to Indians (33-21), 4-2 | American League Park II (10-16) | 17-30 | |
| » Starters: Glenn Liebhardt vs Cy Falkenberg | Seventh | 14½ out |
| Friday, June 21 |
| » Lost to Indians (34-21), 9-0 | American League Park II (10-17) | 17-31 | Lost 2 |
| » Starters: Jake Thielman vs Tom Hughes | Seventh | 15 out |
| Saturday, June 22 |
| » Lost to Athletics (30-24), 4-0 | Columbia Park (0-3) | 17-32 | Lost 3 |
| » Starters: Casey Patten vs Jack Coombs | Eighth | 16 out |
| Monday, June 24 |
| » Lost to Athletics (31-24), 9-2 | Columbia Park (0-4) | 17-33 | Lost 4 |
| » Starters: Charlie Smith vs Eddie Plank | Eighth | 16 out |
| » Lost to Athletics (32-24), 6-3 | Columbia Park (0-5) | 17-34 | Lost 5 |
| » Starters: Cy Falkenberg vs Jimmy Dygert | Eighth | 16 out |
| Tuesday, June 25 |
| » Lost to Athletics (33-24), 3-1 | Columbia Park (0-6) | 17-35 | Lost 6 |
| » Starters: Tom Hughes vs Rube Waddell | Eighth | 17½ out |
| » Lost to Athletics (34-24), 3-2 | Columbia Park (0-7) | 17-36 | Lost 7 |
| » Starters: Charlie Smith vs Chief Bender | Eighth | 17½ out |
| Thursday, June 27 |
| » Lost to Yankees (27-29), 15-7 | Hilltop Park (2-3) | 17-37 | Lost 8 |
| » Starters: Casey Patten vs Jack Chesbro | Eighth | 18 out |
| Friday, June 28 |
| » Defeated Yankees (27-30), 16-5 | Hilltop Park (3-3) | 18-37 | |
| » Starters: Tom Hughes vs Earl Moore | Eighth | 18 out |
| Future Senator Joe Cascarella is born in Philadelphia, PA. |
| Monday, July 1 |
| » Lost to Yankees (28-30), 16-15 | Hilltop Park (3-4) | 18-38 | |
| » Starters: Cy Falkenberg vs Al Orth | Eighth | 20½ out |
| » Lost to Yankees (29-30), 8-4 | Hilltop Park (3-5) | 18-39 | Lost 2 |
| » Starters: Tom Hughes vs Bill Hogg | Eighth | 20½ out |
| Tuesday, July 2 |
| » Defeated Red Sox (23-40), 6-2 | Huntington Ave Baseball Grounds (2-2) | 19-39 | |
| » Starters: Casey Patten vs Jesse Tannehill | Eighth | 19½ out |
| Wednesday, July 3 |
| » Defeated Red Sox (23-41), 6-4 | Huntington Ave Baseball Grounds (3-2) | 20-39 | Won 2 |
| » Starters: Cy Falkenberg vs George Winter | Eighth | 18½ out |
| Thursday, July 4 |
| » Lost to Red Sox (24-41), 3-1 | Huntington Ave Baseball Grounds (3-3) | 20-40 | |
| » Starters: Charlie Smith vs Ralph Glaze | Eighth | 20½ out |
| » Lost to Red Sox (25-41), 7-0 | Huntington Ave Baseball Grounds (3-4) | 20-41 | Lost 2 |
| » Starters: Oscar Graham vs Tex Pruiett | Eighth | 20½ out |
| Saturday, July 6 |
| » Defeated Browns (28-42), 9-5 | Sportsman's Park II (3-2) | 21-41 | |
| » Starters: Casey Patten vs Harry Howell | Eighth | 20 out |
| Sunday, July 7 |
| » Defeated Browns (28-43), 12-6 | Sportsman's Park II (4-2) | 22-41 | Won 2 |
| » Starters: Oscar Graham vs Fred Glade | Eighth | 20 out |
| Monday, July 8 |
| » Lost to Browns (29-43), 3-2 | Sportsman's Park II (4-3) | 22-42 | |
| » Starters: Charlie Smith vs Barney Pelty | Eighth | 20 out |
| Tuesday, July 9 |
| » Lost to Browns (30-43), 5-4 | Sportsman's Park II (4-4) | 22-43 | Lost 2 |
| » Starters: Charlie Smith vs Jack Powell | Eighth | 21 out |
| Thursday, July 11 |
| » Lost to White Sox (46-25), 10-2 | South Side Park III (1-2) | 22-44 | Lost 3 |
| » Starters: Casey Patten vs Frank Smith | Eighth | 21½ out |
| Friday, July 12 |
| » Lost to White Sox (47-25), 9-2 | South Side Park III (1-3) | 22-45 | Lost 4 |
| » Starters: Tom Hughes vs Roy Patterson | Eighth | 22½ out |
| Saturday, July 13 |
| » Lost to White Sox (48-25), 6-4 | South Side Park III (1-4) | 22-46 | Lost 5 |
| » Starters: Oscar Graham vs Ed Walsh | Eighth | 23½ out |
| Sunday, July 14 |
| » Lost to White Sox (49-25), 3-1 | South Side Park III (1-5) | 22-47 | Lost 6 |
| » Starters: Cy Falkenberg vs Frank Smith | Eighth | 23½ out |
| » Defeated White Sox (49-26), 5-3 | South Side Park III (2-5) | 23-47 | |
| » Starters: Casey Patten vs Frank Smith | Eighth | 23½ out |
| Tuesday, July 16 |
| » Lost to Tigers (42-30), 3-0 | Bennett Park (0-3) | 23-48 | |
| » Starters: Charlie Smith vs Ed Siever | Eighth | 24½ out |
| » Defeated Tigers (42-31), 6-1 | Bennett Park (1-3) | 24-48 | |
| » Starters: Tom Hughes vs Ed Willett | Eighth | 24½ out |
| Wednesday, July 17 |
| » Defeated Tigers (42-32), 13-2 | Bennett Park (2-3) | 25-48 | Won 2 |
| » Starters: Oscar Graham vs Ed Killian | Eighth | 24 out |
| Thursday, July 18 |
| » Lost to Tigers (43-32), 5-2 | Bennett Park (2-4) | 25-49 | |
| » Starters: Hank Gehring vs George Mullin | Eighth | 24 out |
| » Lost to Tigers (44-32), 11-2 | Bennett Park (2-5) | 25-50 | Lost 2 |
| » Starters: Casey Patten vs Ed Killian | Eighth | 24 out |
| Friday, July 19 |
| » Tied Indians, 0-0 | League Park I (1-3) | 25-50 | |
| » Starters: Charlie Smith vs Glenn Liebhardt | Eighth | 24 out |
| Saturday, July 20 |
| » Lost to Indians (48-33), 4-1 | League Park I (1-4) | 25-51 | Lost 3 |
| » Starters: Tom Hughes vs Addie Joss | Eighth | 24 out |
| Monday, July 22 |
| » Lost to Indians (49-33), 6-2 | League Park I (1-5) | 25-52 | Lost 4 |
| » Starters: Cy Falkenberg vs Glenn Liebhardt | Eighth | 24½ out |
| Tuesday, July 23 |
| » Lost to Indians (50-33), 3-1 | League Park I (1-6) | 25-53 | Lost 5 |
| » Starters: Charlie Smith vs Walter Clarkson | Eighth | 25 out |
| Wednesday, July 24 |
| » Defeated Browns (34-50), 6-5 | American League Park II (11-17) | 26-53 | |
| » Starters: Cy Morgan vs Casey Patten | Eighth | 24 out |
| Thursday, July 25 |
| » Lost to Browns (35-50), 5-3 | American League Park II (11-18) | 26-54 | |
| » Starters: Jack Powell vs Tom Hughes | Eighth | 23½ out |
| Friday, July 26 |
| » Lost to Browns (36-50), 5-4 | American League Park II (11-19) | 26-55 | Lost 2 |
| » Starters: Harry Howell vs Oscar Graham | Eighth | 23½ out |
| Saturday, July 27 |
| » Defeated Browns (36-51), 8-1 | American League Park II (12-19) | 27-55 | |
| » Starters: Fred Glade vs Charlie Smith | Eighth | 23½ out |
| Monday, July 29 |
| » Major-league debuts: Harry Hinchman (Indians) |
| Tuesday, July 30 |
| » Lost to White Sox (55-35), 4-2 | American League Park II (12-20) | 27-56 | |
| » Starters: Roy Patterson vs Casey Patten | Eighth | 23½ out |
| » Defeated White Sox (55-36), 6-4 | American League Park II (13-20) | 28-56 | |
| » Starters: Doc White vs Cy Falkenberg | Eighth | 23½ out |
| Wednesday, July 31 |
| » Lost to White Sox (56-36), 3-0 | American League Park II (13-21) | 28-57 | |
| » Starters: Ed Walsh vs Hank Gehring | Eighth | 24½ out |
| Thursday, August 1 |
| » Lost to White Sox (57-36), 7-3 | American League Park II (13-22) | 28-58 | Lost 2 |
| » Starters: Frank Smith vs Charlie Smith | Eighth | 25½ out |
| Friday, August 2 |
| » Lost to Tigers (53-35), 3-2 | American League Park II (13-23) | 28-59 | Lost 3 |
| » Starters: Ed Siever vs Walter Johnson | Eighth | 25½ out |
| » Lost to Tigers (54-35), 9-6 | American League Park II (13-24) | 28-60 | Lost 4 |
| » Starters: John Eubank vs Tom Hughes | Eighth | 25½ out |
| Saturday, August 3 |
| » Lost to Tigers (55-35), 12-4 | American League Park II (13-25) | 28-61 | Lost 5 |
| » Starters: George Mullin vs Hank Gehring | Eighth | 27½ out |
| Monday, August 5 |
| » Lost to Tigers (56-35), 8-2 | American League Park II (13-26) | 28-62 | Lost 6 |
| » Starters: Ed Siever vs Oscar Graham | Eighth | 28½ out |
| » Lost to Tigers (57-35), 5-2 | American League Park II (13-27) | 28-63 | Lost 7 |
| » Starters: Bill Donovan vs Charlie Smith | Eighth | 28½ out |
| » Major-league debuts: Bruno Block (Senators) |
| Wednesday, August 7 |
| » Defeated Indians (55-43), 7-2 | American League Park II (14-27) | 29-63 | |
| » Starters: Glenn Liebhardt vs Walter Johnson | Eighth | 27½ out |
| Thursday, August 8 |
| » Lost to Indians (56-43), 4-2 | American League Park II (14-28) | 29-64 | |
| » Starters: Bob Rhoads vs Cy Falkenberg | Eighth | 28½ out |
| Saturday, August 10 |
| » Lost to Indians (57-43), 2-1 | American League Park II (14-29) | 29-65 | Lost 2 |
| » Starters: Addie Joss vs Charlie Smith | Eighth | 28½ out |
| Sunday, August 11 |
| Future Senator Bobo Newsom is born in Hartsville, SC. |
| Monday, August 12 |
| » Lost to Browns (41-57), 7-3 | Sportsman's Park II (4-5) | 29-66 | Lost 3 |
| » Starters: Casey Patten vs Fred Glade | Eighth | 29 out |
| » Major-league debuts: Tony Smith (Senators) |
| Tuesday, August 13 |
| » Lost to Browns (42-57), 6-5 | Sportsman's Park II (4-6) | 29-67 | Lost 4 |
| » Starters: Frank Oberlin vs Jack Powell | Eighth | 30 out |
| Future Senator Art Shires is born in Italy, TX. |
| Wednesday, August 14 |
| » Lost to Browns (43-57), 1-0 | Sportsman's Park II (4-7) | 29-68 | Lost 5 |
| » Starters: Walter Johnson vs Barney Pelty | Eighth | 30 out |
| Friday, August 16 |
| » Lost to White Sox (64-44), 3-2 | South Side Park III (2-6) | 29-69 | Lost 6 |
| » Starters: Cy Falkenberg vs Ed Walsh | Eighth | 31 out |
| Saturday, August 17 |
| » Defeated White Sox (64-45), 2-0 | South Side Park III (3-6) | 30-69 | |
| » Starters: Charlie Smith vs Roy Patterson | Eighth | 30 out |
| Sunday, August 18 |
| » Defeated White Sox (64-46), 5-2 | South Side Park III (4-6) | 31-69 | Won 2 |
| » Starters: Casey Patten vs Nick Altrock | Eighth | 29½ out |
| Monday, August 19 |
| » Lost to White Sox (65-46), 16-2 | South Side Park III (4-7) | 31-70 | |
| » Starters: Frank Oberlin vs Doc White | Eighth | 30½ out |
| » Major-league debuts: Clyde Milan (Senators) |
| Tuesday, August 20 |
| » Lost to Indians (62-47), 3-0 | League Park I (1-7) | 31-71 | Lost 2 |
| » Starters: Walter Johnson vs Bob Rhoads | Eighth | 30½ out |
| » Tied Indians, 1-1 | League Park I (1-7) | 31-71 | |
| » Starters: Cy Falkenberg vs Addie Joss | Eighth | 30½ out |
| Wednesday, August 21 |
| » Lost to Indians (63-47), 2-1 | League Park I (1-8) | 31-72 | Lost 3 |
| » Starters: Charlie Smith vs Jake Thielman | Eighth | 31 out |
| » Lost to Indians (64-47), 6-4 | League Park I (1-9) | 31-73 | Lost 4 |
| » Starters: Hank Gehring vs Glenn Liebhardt | Eighth | 31 out |
| Thursday, August 22 |
| » Lost to Indians (65-47), 2-1 | League Park I (1-10) | 31-74 | Lost 5 |
| » Starters: Casey Patten vs Walter Clarkson | Eighth | 32 out |
| Friday, August 23 |
| » Defeated Tigers (63-44), 3-1 | Bennett Park (3-5) | 32-74 | |
| » Starters: Cy Falkenberg vs Ed Siever | Eighth | 32 out |
| Saturday, August 24 |
| » Lost to Tigers (64-44), 8-5 | Bennett Park (3-6) | 32-75 | |
| » Starters: Frank Oberlin vs George Mullin | Eighth | 32½ out |
| Monday, August 26 |
| » Lost to Tigers (66-44), 7-4 | Bennett Park (3-7) | 32-76 | Lost 2 |
| » Starters: Charlie Smith vs Ed Siever | Eighth | 33 out |
| » Major-league debuts: Tex Erwin (Tigers) |
| Tuesday, August 27 |
| » Lost to Tigers (67-44), 4-3 | Bennett Park (3-8) | 32-77 | Lost 3 |
| » Starters: Cy Falkenberg vs George Mullin | Eighth | 34 out |
| Thursday, August 29 |
| » Defeated Red Sox (51-67), 3-2 | American League Park II (15-29) | 33-77 | |
| » Starters: George Winter vs Charlie Smith | Eighth | 34 out |
| » Defeated Red Sox (51-68), 2-1 | American League Park II (16-29) | 34-77 | Won 2 |
| » Starters: Ralph Glaze vs Walter Johnson | Eighth | 34 out |
| Friday, August 30 |
| » Lost to Red Sox (52-68), 4-3 | American League Park II (16-30) | 34-78 | |
| » Starters: Cy Morgan vs Casey Patten | Eighth | 34½ out |
| Saturday, August 31 |
| » Defeated Red Sox (52-69), 1-0 | American League Park II (17-30) | 35-78 | |
| » Starters: Rube Kroh vs Hank Gehring | Eighth | 34½ out |
| Monday, September 2 |
| » Defeated Athletics (69-47), 3-1 | Columbia Park (1-7) | 36-78 | Won 2 |
| » Starters: Charlie Smith vs Jack Coombs | Eighth | 34 out |
| » Lost to Athletics (70-47), 3-2 | Columbia Park (1-8) | 36-79 | |
| » Starters: Walter Johnson vs Eddie Plank | Eighth | 34 out |
| Tuesday, September 3 |
| » Lost to Athletics (71-47), 15-6 | Columbia Park (1-9) | 36-80 | Lost 2 |
| » Starters: Frank Oberlin vs Jimmy Dygert | Eighth | 35½ out |
| » Lost to Athletics (72-47), 9-1 | Columbia Park (1-10) | 36-81 | Lost 3 |
| » Starters: Cy Falkenberg vs Rube Waddell | Eighth | 35½ out |
| » Major-league debuts: John McDonald (Senators) |
| Friday, September 6 |
| » Lost to Red Sox (55-70), 9-2 | Huntington Ave Baseball Grounds (3-5) | 36-82 | Lost 4 |
| » Starters: Casey Patten vs Cy Young | Eighth | 37 out |
| » Lost to Red Sox (56-70), 3-2 | Huntington Ave Baseball Grounds (3-6) | 36-83 | Lost 5 |
| » Starters: Cy Falkenberg vs Ralph Glaze | Eighth | 37 out |
| Saturday, September 7 |
| » Defeated Red Sox (56-71), 1-0 | Huntington Ave Baseball Grounds (4-6) | 37-83 | |
| » Starters: Walter Johnson vs Cy Morgan | Eighth | 36½ out |
| » Defeated Red Sox (56-72), 4-1 | Huntington Ave Baseball Grounds (5-6) | 38-83 | Won 2 |
| » Starters: Charlie Smith vs Rube Kroh | Eighth | 36½ out |
| Monday, September 9 |
| » Lost to Yankees (57-68), 10-0 | American League Park II (17-31) | 38-84 | |
| » Starters: Tex Neuer vs Tom Hughes | Eighth | 37½ out |
| » Lost to Yankees (58-68), 2-0 | American League Park II (17-32) | 38-85 | Lost 2 |
| » Starters: Jack Chesbro vs Hank Gehring | Eighth | 37½ out |
| Tuesday, September 10 |
| » Lost to Yankees (59-68), 1-0 | American League Park II (17-33) | 38-86 | Lost 3 |
| » Starters: Slow Joe Doyle vs Frank Oberlin | Eighth | 38½ out |
| » Lost to Yankees (60-68), 5-3 | American League Park II (17-34) | 38-87 | Lost 4 |
| » Starters: Al Orth vs Casey Patten | Eighth | 38½ out |
| Wednesday, September 11 |
| » Lost to Yankees (61-68), 4-2 | American League Park II (17-35) | 38-88 | Lost 5 |
| » Starters: Bill Hogg vs Cy Falkenberg | Eighth | 38½ out |
| Thursday, September 12 |
| » Defeated Yankees (61-69), 2-0 | Hilltop Park (4-5) | 39-88 | |
| » Starters: Walter Johnson vs Doc Newton | Eighth | 38½ out |
| » Major-league debuts: Neal Ball (Yankees) |
| Friday, September 13 |
| » Defeated Yankees (61-70), 10-2 | Hilltop Park (5-5) | 40-88 | Won 2 |
| » Starters: Hank Gehring vs Tex Neuer | Eighth | 38 out |
| » Major-league debuts: Baldy Louden (Yankees) |
| Saturday, September 14 |
| » Lost to Yankees (62-70), 8-2 | Hilltop Park (5-6) | 40-89 | |
| » Starters: Sam Lanford vs Slow Joe Doyle | Eighth | 39½ out |
| Monday, September 16 |
| » Defeated Red Sox (58-77), 3-2 | American League Park II (18-35) | 41-89 | |
| » Starters: Ralph Glaze vs Charlie Smith | Eighth | 38 out |
| » Defeated Red Sox (58-78), 6-0 | American League Park II (19-35) | 42-89 | Won 2 |
| » Starters: Elmer Steele vs Cy Falkenberg | Eighth | 38 out |
| Tuesday, September 17 |
| » Defeated Red Sox (58-79), 9-1 | American League Park II (20-35) | 43-89 | Won 3 |
| » Starters: George Winter vs Tom Hughes | Eighth | 37 out |
| Wednesday, September 18 |
| » Defeated Red Sox (58-80), 2-1 | American League Park II (21-35) | 44-89 | Won 4 |
| » Starters: Cy Morgan vs Frank Oberlin | Eighth | 36½ out |
| Friday, September 20 |
| » Lost to White Sox (81-58), 2-1 | American League Park II (21-36) | 44-90 | |
| » Starters: Frank Smith vs Walter Johnson | Eighth | 37 out |
| » Lost to White Sox (82-58), 13-6 | American League Park II (21-37) | 44-91 | Lost 2 |
| » Starters: Ed Walsh vs Casey Patten | Eighth | 37 out |
| Saturday, September 21 |
| » Lost to White Sox (83-58), 5-3 | American League Park II (21-38) | 44-92 | Lost 3 |
| » Starters: Doc White vs Charlie Smith | Eighth | 38 out |
| Tuesday, September 24 |
| » Lost to Browns (60-80), 10-3 | American League Park II (21-39) | 44-93 | Lost 4 |
| » Starters: Barney Pelty vs Walter Johnson | Eighth | 38½ out |
| Wednesday, September 25 |
| » Defeated Browns (60-81), 5-4 | American League Park II (22-39) | 45-93 | |
| » Starters: Bill Bailey vs Charlie Smith | Eighth | 38½ out |
| Thursday, September 26 |
| » Lost to Browns (61-81), 2-1 | American League Park II (22-40) | 45-94 | |
| » Starters: Jack Powell vs Casey Patten | Eighth | 39½ out |
| Friday, September 27 |
| » Lost to Indians (83-61), 3-0 | American League Park II (22-41) | 45-95 | Lost 2 |
| » Starters: Jake Thielman vs Tom Hughes | Eighth | 40 out |
| » Defeated Indians (83-62), 9-4 | American League Park II (23-41) | 46-95 | |
| » Starters: Bill Bernhard vs Cy Falkenberg | Eighth | 40 out |
| Saturday, September 28 |
| » Defeated Indians (83-63), 3-1 | American League Park II (24-41) | 47-95 | Won 2 |
| » Starters: Glenn Liebhardt vs Frank Oberlin | Eighth | 39½ out |
| Monday, September 30 |
| » Defeated Indians (83-64), 6-0 | American League Park II (25-41) | 48-95 | Won 3 |
| » Starters: Addie Joss vs Hank Gehring | Eighth | 39 out |
| Tuesday, October 1 |
| » Lost to Tigers (88-56), 5-3 | American League Park II (25-42) | 48-96 | |
| » Starters: Ed Siever vs Walter Johnson | Eighth | 40 out |
| Wednesday, October 2 |
| » Lost to Tigers (89-56), 9-5 | American League Park II (25-43) | 48-97 | Lost 2 |
| » Starters: Ed Killian vs Charlie Smith | Eighth | 42 out |
| » Lost to Tigers (90-56), 10-2 | American League Park II (25-44) | 48-98 | Lost 3 |
| » Starters: George Mullin vs Frank Oberlin | Eighth | 42 out |
| Thursday, October 3 |
| » Lost to Tigers (91-56), 9-3 | American League Park II (25-45) | 48-99 | Lost 4 |
| » Starters: Bill Donovan vs Hank Gehring | Eighth | 43 out |
| Friday, October 4 |
| » Defeated Athletics (85-57), 2-1 | American League Park II (26-45) | 49-99 | |
| » Starters: Eddie Plank vs Walter Johnson | Eighth | 43 out |
| » Lost to Athletics (86-57), 8-0 | American League Park II (26-46) | 49-100 | |
| » Starters: Jimmy Dygert vs Tom Hughes | Eighth | 43 out |
| Saturday, October 5 |
| » Lost to Athletics (87-57), 4-2 | American League Park II (26-47) | 49-101 | Lost 2 |
| » Starters: Charlie Fritz vs Charlie Smith | Eighth | 44½ out |
| » Lost to Athletics (88-57), 4-0 | American League Park II (26-48) | 49-102 | Lost 3 |
| » Starters: Rube Vickers vs Cy Falkenberg | Eighth | 44½ out |
| » Major-league debuts: Charlie Fritz (Athletics) |
Game information provided by Retrosheet (www.retrosheet.org) |