| Friday, January 26 |
| Future Red Sox Charley Gelbert is born in Scranton, PA. |
| Sunday, January 28 |
| Future Red Sox Lyn Lary is born in Armona, CA. |
| Saturday, March 17 |
| Future Red Sox Hy Vandenberg is born in Abilene, KS. |
| Thursday, March 22 |
| Future Red Sox Marv Owen is born in Agnew, CA. Future Red Sox Moose Solters is born in Pittsburgh, PA. |
| Thursday, April 12 |
| » Major-league debuts: Pug Bennett (Cardinals) |
| Saturday, April 14 |
| » Lost to Yankees (1-0), 2-1 | Hilltop Park (0-1) | 0-1 | |
| » Starters: Cy Young vs Jack Chesbro | Third | 1 out |
| Sunday, April 15 |
| » Major-league debuts: Ed Karger (Pirates) |
| Monday, April 16 |
| » Lost to Yankees (2-0), 4-3 | Hilltop Park (0-2) | 0-2 | Lost 2 |
| » Starters: Bill Dinneen vs Doc Newton | Third | 2 out |
| Tuesday, April 17 |
| » Lost to Yankees (3-0), 4-3 | Huntington Ave Baseball Grounds (0-1) | 0-3 | Lost 3 |
| » Starters: Bill Hogg vs George Winter | Sixth | 3 out |
| Wednesday, April 18 |
| » Tied Yankees, 3-3 | Huntington Ave Baseball Grounds (0-1) | 0-3 | |
| » Starters: Walter Clarkson vs Joe Harris | Seventh | 3 out |
| » Major-league debuts: Bob Peterson (Red Sox) |
| Thursday, April 19 |
| » Defeated Yankees (3-1), 2-0 | Huntington Ave Baseball Grounds (1-1) | 1-3 | |
| » Starters: Jack Chesbro vs Jesse Tannehill | Fourth | 2 out |
| » Defeated Yankees (3-2), 3-1 | Huntington Ave Baseball Grounds (2-1) | 2-3 | Won 2 |
| » Starters: Doc Newton vs Cy Young | Fourth | 2 out |
| Friday, April 20 |
| » Lost to Senators (3-3), 10-1 | American League Park II (0-1) | 2-4 | |
| » Starters: George Winter vs Cy Falkenberg | Fifth | 2½ out |
| Saturday, April 21 |
| » Lost to Senators (4-3), 4-3 | American League Park II (0-2) | 2-5 | Lost 2 |
| » Starters: Bill Dinneen vs Charlie Smith | Seventh | 2½ out |
| Tuesday, April 24 |
| » Defeated Senators (4-4), 19-2 | American League Park II (1-2) | 3-5 | |
| » Starters: Jesse Tannehill vs Cy Falkenberg | Sixth | 2 out |
| Wednesday, April 25 |
| » Lost to Athletics (6-3), 5-0 | Columbia Park (0-1) | 3-6 | |
| » Starters: Cy Young vs Rube Waddell | Sixth | 3 out |
| Thursday, April 26 |
| » Defeated Athletics (6-4), 12-0 | Columbia Park (1-1) | 4-6 | |
| » Starters: George Winter vs Andy Coakley | Fifth | 2 out |
| Friday, April 27 |
| » Lost to Athletics (7-4), 3-0 | Columbia Park (1-2) | 4-7 | |
| » Starters: Cy Young vs Eddie Plank | Fourth | 3 out |
| Saturday, April 28 |
| » Defeated Athletics (7-5), 7-6 | Columbia Park (2-2) | 5-7 | |
| » Starters: Bill Dinneen vs Rube Waddell | Fifth | 2 out |
| Monday, April 30 |
| » Defeated Yankees (5-8), 13-4 | Hilltop Park (1-2) | 6-7 | Won 2 |
| » Starters: Jesse Tannehill vs Jack Chesbro | Fourth | 2 out |
| Tuesday, May 1 |
| » Lost to Yankees (6-8), 8-0 | Hilltop Park (1-3) | 6-8 | |
| » Starters: Norwood Gibson vs Bill Hogg | Sixth | 3 out |
| Wednesday, May 2 |
| » Lost to Senators (8-7), 3-2 | Huntington Ave Baseball Grounds (2-2) | 6-9 | Lost 2 |
| » Starters: Casey Patten vs Cy Young | Seventh | 3½ out |
| Thursday, May 3 |
| » Lost to Senators (9-7), 6-4 | Huntington Ave Baseball Grounds (2-3) | 6-10 | Lost 3 |
| » Starters: Frank Kitson vs George Winter | Seventh | 3½ out |
| Friday, May 4 |
| » Lost to Senators (10-7), 4-2 | Huntington Ave Baseball Grounds (2-4) | 6-11 | Lost 4 |
| » Starters: Tom Hughes vs Bill Dinneen | Seventh | 4 out |
| Monday, May 7 |
| » Lost to Athletics (11-7), 4-0 | Huntington Ave Baseball Grounds (2-5) | 6-12 | Lost 5 |
| » Starters: Rube Waddell vs George Winter | Seventh | 5 out |
| Tuesday, May 8 |
| » Lost to Athletics (12-7), 11-4 | Huntington Ave Baseball Grounds (2-6) | 6-13 | Lost 6 |
| » Starters: Andy Coakley vs Jesse Tannehill | Seventh | 6 out |
| Wednesday, May 9 |
| » Lost to Athletics (13-7), 9-6 | Huntington Ave Baseball Grounds (2-7) | 6-14 | Lost 7 |
| » Starters: Eddie Plank vs Cy Young | Eighth | 7 out |
| Thursday, May 10 |
| » Lost to Athletics (14-7), 5-1 | Huntington Ave Baseball Grounds (2-8) | 6-15 | Lost 8 |
| » Starters: Chief Bender vs Joe Harris | Eighth | 8 out |
| Friday, May 11 |
| » Lost to Browns (11-10), 8-3 | Huntington Ave Baseball Grounds (2-9) | 6-16 | Lost 9 |
| » Starters: Ed Smith vs Bill Dinneen | Eighth | 8½ out |
| Saturday, May 12 |
| » Lost to Browns (12-10), 9-1 | Huntington Ave Baseball Grounds (2-10) | 6-17 | Lost 10 |
| » Starters: Fred Glade vs Norwood Gibson | Eighth | 9½ out |
| Monday, May 14 |
| » Lost to Browns (13-10), 11-1 | Huntington Ave Baseball Grounds (2-11) | 6-18 | Lost 11 |
| » Starters: Harry Howell vs Cy Young | Eighth | 10 out |
| Tuesday, May 15 |
| » Lost to Browns (14-10), 9-5 | Huntington Ave Baseball Grounds (2-12) | 6-19 | Lost 12 |
| » Starters: Barney Pelty vs Jesse Tannehill | Eighth | 11 out |
| Wednesday, May 16 |
| » Lost to Indians (12-9), 7-6 | Huntington Ave Baseball Grounds (2-13) | 6-20 | Lost 13 |
| » Starters: Bob Rhoads vs George Winter | Eighth | 12 out |
| Thursday, May 17 |
| » Lost to Indians (13-9), 7-4 | Huntington Ave Baseball Grounds (2-14) | 6-21 | Lost 14 |
| » Starters: Otto Hess vs Joe Harris | Eighth | 13 out |
| Friday, May 18 |
| » Lost to Indians (14-9), 14-1 | Huntington Ave Baseball Grounds (2-15) | 6-22 | Lost 15 |
| » Starters: Addie Joss vs Bill Dinneen | Seventh | 14 out |
| Saturday, May 19 |
| » Lost to Indians (15-9), 3-2 | Huntington Ave Baseball Grounds (2-16) | 6-23 | Lost 16 |
| » Starters: Bill Bernhard vs Cy Young | Eighth | 15 out |
| Monday, May 21 |
| » Lost to Tigers (14-13), 2-1 | Huntington Ave Baseball Grounds (2-17) | 6-24 | Lost 17 |
| » Starters: George Mullin vs George Winter | Seventh | 15 out |
| Future Red Sox Hank Johnson is born in Bradenton, FL. |
| Tuesday, May 22 |
| » Lost to Tigers (15-13), 6-3 | Huntington Ave Baseball Grounds (2-18) | 6-25 | Lost 18 |
| » Starters: Ed Siever vs Joe Harris | Seventh | 15 out |
| Wednesday, May 23 |
| » Lost to Tigers (16-13), 3-2 | Huntington Ave Baseball Grounds (2-19) | 6-26 | Lost 19 |
| » Starters: Ed Killian vs Bill Dinneen | Seventh | 16 out |
| Thursday, May 24 |
| » Lost to White Sox (14-15), 7-5 | Huntington Ave Baseball Grounds (2-20) | 6-27 | Lost 20 |
| » Starters: Nick Altrock vs Cy Young | Eighth | 16 out |
| Friday, May 25 |
| » Defeated White Sox (14-16), 3-0 | Huntington Ave Baseball Grounds (3-20) | 7-27 | |
| » Starters: Doc White vs Jesse Tannehill | Eighth | 16 out |
| Saturday, May 26 |
| » Defeated White Sox (14-17), 4-2 | Huntington Ave Baseball Grounds (4-20) | 8-27 | Won 2 |
| » Starters: Frank Owen vs Cy Young | Eighth | 16 out |
| Tuesday, May 29 |
| » Lost to Athletics (24-10), 2-1 | Huntington Ave Baseball Grounds (4-21) | 8-28 | |
| » Starters: Eddie Plank vs Joe Harris | Eighth | 17 out |
| Wednesday, May 30 |
| » Defeated Athletics (24-11), 5-1 | Huntington Ave Baseball Grounds (5-21) | 9-28 | |
| » Starters: Andy Coakley vs Bill Dinneen | Eighth | 15 out |
| » Defeated Athletics (24-12), 5-3 | Huntington Ave Baseball Grounds (6-21) | 10-28 | Won 2 |
| » Starters: Chief Bender vs George Winter | Eighth | 15 out |
| Thursday, May 31 |
| » Lost to Senators (14-23), 9-2 | Huntington Ave Baseball Grounds (6-22) | 10-29 | |
| » Starters: Cy Falkenberg vs Jesse Tannehill | Eighth | 15 out |
| Friday, June 1 |
| » Lost to Senators (15-23), 4-0 | Huntington Ave Baseball Grounds (6-23) | 10-30 | Lost 2 |
| » Starters: Casey Patten vs Joe Harris | Eighth | 15 out |
| » Defeated Senators (15-24), 12-8 | Huntington Ave Baseball Grounds (7-23) | 11-30 | |
| » Starters: Willie Sudhoff vs Ralph Glaze | Eighth | 15 out |
| » Major-league debuts: Ralph Glaze (Red Sox) |
| Saturday, June 2 |
| » Defeated Senators (15-25), 6-2 | Huntington Ave Baseball Grounds (8-23) | 12-30 | Won 2 |
| » Starters: Tom Hughes vs Jesse Tannehill | Eighth | 14½ out |
| Monday, June 4 |
| » Defeated Indians (23-15), 6-5 | League Park I (1-0) | 13-30 | Won 3 |
| » Starters: Cy Young vs Bill Bernhard | Eighth | 14½ out |
| Wednesday, June 6 |
| » Lost to Indians (24-15), 3-1 | League Park I (1-1) | 13-31 | |
| » Starters: George Winter vs Bob Rhoads | Eighth | 14 out |
| Thursday, June 7 |
| » Lost to Indians (25-15), 4-0 | League Park I (1-2) | 13-32 | Lost 2 |
| » Starters: Joe Harris vs Addie Joss | Eighth | 15 out |
| Friday, June 8 |
| » Lost to Tigers (23-19), 4-2 | Bennett Park (0-1) | 13-33 | Lost 3 |
| » Starters: Bill Dinneen vs George Mullin | Eighth | 16 out |
| Saturday, June 9 |
| » Lost to Tigers (24-19), 7-6 | Bennett Park (0-2) | 13-34 | Lost 4 |
| » Starters: Cy Young vs Bill Donovan | Eighth | 17 out |
| Monday, June 11 |
| » Defeated Tigers (24-20), 7-5 | Bennett Park (1-2) | 14-34 | |
| » Starters: Jesse Tannehill vs Ed Siever | Eighth | 16½ out |
| Tuesday, June 12 |
| » Lost to Browns (25-24), 15-3 | Sportsman's Park II (0-1) | 14-35 | |
| » Starters: George Winter vs Barney Pelty | Eighth | 16½ out |
| Wednesday, June 13 |
| » Lost to Browns (26-24), 1-0 | Sportsman's Park II (0-2) | 14-36 | Lost 2 |
| » Starters: Bill Dinneen vs Fred Glade | Eighth | 17½ out |
| Friday, June 15 |
| » Defeated Browns (26-25), 3-2 | Sportsman's Park II (1-2) | 15-36 | |
| » Starters: Cy Young vs Beany Jacobson | Eighth | 16 out |
| Future Red Sox Monte Weaver is born in Helton, NC. |
| Saturday, June 16 |
| » Lost to White Sox (24-25), 6-0 | South Side Park III (0-1) | 15-37 | |
| » Starters: Jesse Tannehill vs Nick Altrock | Eighth | 17 out |
| Sunday, June 17 |
| » Lost to White Sox (25-25), 3-1 | South Side Park III (0-2) | 15-38 | Lost 2 |
| » Starters: Joe Harris vs Doc White | Eighth | 17½ out |
| Monday, June 18 |
| » Lost to White Sox (26-25), 4-3 | South Side Park III (0-3) | 15-39 | Lost 3 |
| » Starters: Bill Dinneen vs Frank Owen | Eighth | 17½ out |
| Wednesday, June 20 |
| » Lost to White Sox (27-25), 2-1 | South Side Park III (0-4) | 15-40 | Lost 4 |
| » Starters: Cy Young vs Nick Altrock | Eighth | 18 out |
| Friday, June 22 |
| » Defeated Athletics (32-23), 6-4 | Columbia Park (3-2) | 16-40 | |
| » Starters: George Winter vs Andy Coakley | Eighth | 19 out |
| Saturday, June 23 |
| » Lost to Athletics (33-23), 8-0 | Columbia Park (3-3) | 16-41 | |
| » Starters: Joe Harris vs Eddie Plank | Eighth | 19 out |
| Monday, June 25 |
| » Lost to Athletics (34-23), 1-0 | Columbia Park (3-4) | 16-42 | Lost 2 |
| » Starters: Bill Dinneen vs Rube Waddell | Eighth | 20 out |
| Tuesday, June 26 |
| » Lost to Athletics (35-23), 3-1 | Columbia Park (3-5) | 16-43 | Lost 3 |
| » Starters: Cy Young vs Chief Bender | Seventh | 20 out |
| Wednesday, June 27 |
| » Lost to Yankees (35-24), 6-5 | Hilltop Park (1-4) | 16-44 | Lost 4 |
| » Starters: George Winter vs Al Orth | Eighth | 20½ out |
| Thursday, June 28 |
| » Lost to Yankees (36-24), 7-4 | Hilltop Park (1-5) | 16-45 | Lost 5 |
| » Starters: Joe Harris vs Bill Hogg | Fifth | 20½ out |
| Friday, June 29 |
| » Lost to Yankees (37-24), 8-4 | Hilltop Park (1-6) | 16-46 | Lost 6 |
| » Starters: Bill Dinneen vs Jack Chesbro | Seventh | 21½ out |
| Monday, July 2 |
| » Defeated Senators (22-41), 4-3 | American League Park II (2-2) | 17-46 | |
| » Starters: Cy Young vs Charlie Smith | Seventh | 21½ out |
| » Lost to Senators (23-41), 17-3 | American League Park II (2-3) | 17-47 | |
| » Starters: George Winter vs Cy Falkenberg | Seventh | 21½ out |
| Tuesday, July 3 |
| » Lost to Senators (24-41), 5-0 | American League Park II (2-4) | 17-48 | Lost 2 |
| » Starters: Joe Harris vs Frank Kitson | Eighth | 22½ out |
| Wednesday, July 4 |
| » Lost to Senators (25-41), 8-1 | American League Park II (2-5) | 17-49 | Lost 3 |
| » Starters: Bill Dinneen vs Casey Patten | Eighth | 23½ out |
| » Defeated Senators (25-42), 9-3 | American League Park II (3-5) | 18-49 | |
| » Starters: Cy Young vs Tom Hughes | Eighth | 23½ out |
| Thursday, July 5 |
| » Lost to Yankees (40-26), 8-3 | Huntington Ave Baseball Grounds (8-24) | 18-50 | |
| » Starters: Bill Hogg vs Joe Harris | Eighth | 23½ out |
| Friday, July 6 |
| » Lost to Yankees (41-26), 4-0 | Huntington Ave Baseball Grounds (8-25) | 18-51 | Lost 2 |
| » Starters: Jack Chesbro vs Bill Dinneen | Seventh | 25 out |
| » Lost to Yankees (42-26), 8-0 | Huntington Ave Baseball Grounds (8-26) | 18-52 | Lost 3 |
| » Starters: Doc Newton vs Cy Young | Seventh | 25 out |
| Saturday, July 7 |
| » Lost to White Sox (39-31), 12-0 | Huntington Ave Baseball Grounds (8-27) | 18-53 | Lost 4 |
| » Starters: Doc White vs Joe Harris | Eighth | 25½ out |
| » Major-league debuts: Bill Carrigan (Red Sox) |
| Monday, July 9 |
| » Defeated White Sox (39-32), 5-2 | Huntington Ave Baseball Grounds (9-27) | 19-53 | |
| » Starters: Frank Owen vs Bill Dinneen | Seventh | 25 out |
| Tuesday, July 10 |
| » Lost to White Sox (40-32), 6-3 | Huntington Ave Baseball Grounds (9-28) | 19-54 | |
| » Starters: Ed Walsh vs Jesse Tannehill | Seventh | 25½ out |
| Wednesday, July 11 |
| » Lost to White Sox (41-32), 2-1 | Huntington Ave Baseball Grounds (9-29) | 19-55 | Lost 2 |
| » Starters: Nick Altrock vs Cy Young | Seventh | 26½ out |
| » Lost to White Sox (42-32), 8-0 | Huntington Ave Baseball Grounds (9-30) | 19-56 | Lost 3 |
| » Starters: Roy Patterson vs Joe Harris | Seventh | 26½ out |
| Thursday, July 12 |
| » Lost to Browns (37-38), 4-1 | Huntington Ave Baseball Grounds (9-31) | 19-57 | Lost 4 |
| » Starters: Jack Powell vs Bill Dinneen | Seventh | 27½ out |
| Friday, July 13 |
| » Lost to Browns (38-38), 8-1 | Huntington Ave Baseball Grounds (9-32) | 19-58 | Lost 5 |
| » Starters: Barney Pelty vs Jesse Tannehill | Seventh | 27½ out |
| Saturday, July 14 |
| » Lost to Browns (39-38), 3-0 | Huntington Ave Baseball Grounds (9-33) | 19-59 | Lost 6 |
| » Starters: Harry Howell vs Cy Young | Seventh | 28½ out |
| Monday, July 16 |
| » Lost to Browns (40-38), 2-0 | Huntington Ave Baseball Grounds (9-34) | 19-60 | Lost 7 |
| » Starters: Fred Glade vs Ralph Glaze | Eighth | 29½ out |
| Tuesday, July 17 |
| » Lost to Tigers (41-37), 5-3 | Huntington Ave Baseball Grounds (9-35) | 19-61 | Lost 8 |
| » Starters: Ed Killian vs Jesse Tannehill | Eighth | 30 out |
| Wednesday, July 18 |
| » Defeated Tigers (41-38), 5-2 | Huntington Ave Baseball Grounds (10-35) | 20-61 | |
| » Starters: George Mullin vs Bill Dinneen | Eighth | 29½ out |
| Thursday, July 19 |
| » Lost to Tigers (42-38), 6-1 | Huntington Ave Baseball Grounds (10-36) | 20-62 | |
| » Starters: George Mullin vs Cy Young | Eighth | 29½ out |
| Friday, July 20 |
| » Lost to Tigers (43-38), 4-3 | Huntington Ave Baseball Grounds (10-37) | 20-63 | Lost 2 |
| » Starters: Ed Siever vs Ralph Glaze | Eighth | 30½ out |
| Monday, July 23 |
| » Defeated Indians (48-34), 3-1 | Huntington Ave Baseball Grounds (11-37) | 21-63 | |
| » Starters: Happy Townsend vs Bill Dinneen | Eighth | 30½ out |
| Tuesday, July 24 |
| » Defeated Indians (48-35), 5-1 | Huntington Ave Baseball Grounds (12-37) | 22-63 | Won 2 |
| » Starters: Addie Joss vs Cy Young | Eighth | 30 out |
| » Defeated Indians (48-36), 9-2 | Huntington Ave Baseball Grounds (13-37) | 23-63 | Won 3 |
| » Starters: Bob Rhoads vs Jesse Tannehill | Eighth | 30 out |
| Wednesday, July 25 |
| » Lost to Indians (49-36), 3-2 | Huntington Ave Baseball Grounds (13-38) | 23-64 | |
| » Starters: Bill Bernhard vs Joe Harris | Eighth | 31½ out |
| Thursday, July 26 |
| » Lost to Tigers (45-42), 7-4 | Bennett Park (1-3) | 23-65 | Lost 2 |
| » Starters: Cy Young vs Ed Killian | Eighth | 32 out |
| Friday, July 27 |
| » Defeated Browns (42-44), 1-0 | Sportsman's Park II (2-2) | 24-65 | |
| » Starters: Bill Dinneen vs Jack Powell | Eighth | 31½ out |
| Saturday, July 28 |
| » Lost to Browns (43-44), 5-1 | Sportsman's Park II (2-3) | 24-66 | |
| » Starters: Ralph Glaze vs Barney Pelty | Eighth | 32½ out |
| Sunday, July 29 |
| » Lost to Browns (44-44), 8-5 | Sportsman's Park II (2-4) | 24-67 | Lost 2 |
| » Starters: Jesse Tannehill vs Harry Howell | Eighth | 33 out |
| Monday, July 30 |
| » Defeated Browns (44-45), 5-3 | Sportsman's Park II (3-4) | 25-67 | |
| » Starters: Joe Harris vs Fred Glade | Eighth | 33 out |
| Tuesday, July 31 |
| » Lost to Browns (45-45), 2-1 | Sportsman's Park II (3-5) | 25-68 | |
| » Starters: Bill Dinneen vs Jack Powell | Eighth | 33 out |
| Wednesday, August 1 |
| » Defeated White Sox (50-43), 3-1 | South Side Park III (1-4) | 26-68 | |
| » Starters: Jesse Tannehill vs Nick Altrock | Eighth | 32 out |
| Thursday, August 2 |
| » Lost to White Sox (51-43), 3-0 | South Side Park III (1-5) | 26-69 | |
| » Starters: Cy Young vs Doc White | Seventh | 33 out |
| Friday, August 3 |
| » Lost to White Sox (52-43), 4-0 | South Side Park III (1-6) | 26-70 | Lost 2 |
| » Starters: Joe Harris vs Ed Walsh | Eighth | 34 out |
| Saturday, August 4 |
| » Lost to White Sox (53-43), 1-0 | South Side Park III (1-7) | 26-71 | Lost 3 |
| » Starters: Bill Dinneen vs Roy Patterson | Eighth | 35 out |
| Monday, August 6 |
| » Lost to Indians (53-41), 4-0 | League Park I (1-3) | 26-72 | Lost 4 |
| » Starters: Jesse Tannehill vs Addie Joss | Eighth | 34½ out |
| Wednesday, August 8 |
| » Defeated Indians (53-42), 3-1 | League Park I (2-3) | 27-72 | |
| » Starters: Cy Young vs Bill Bernhard | Eighth | 32½ out |
| » Defeated Indians (53-43), 1-0 | League Park I (3-3) | 28-72 | Won 2 |
| » Starters: Joe Harris vs Bob Rhoads | Eighth | 32½ out |
| Friday, August 10 |
| » Defeated Tigers (49-51), 4-3 | Bennett Park (2-3) | 29-72 | Won 3 |
| » Starters: Bill Dinneen vs John Eubank | Eighth | 31 out |
| Saturday, August 11 |
| » Defeated Tigers (49-52), 3-2 | Bennett Park (3-3) | 30-72 | Won 4 |
| » Starters: Jesse Tannehill vs Red Donahue | Eighth | 30½ out |
| » Lost to Tigers (50-52), 7-3 | Bennett Park (3-4) | 30-73 | |
| » Starters: George Winter vs George Mullin | Eighth | 30½ out |
| Monday, August 13 |
| » Defeated Tigers (50-53), 5-4 | Bennett Park (4-4) | 31-73 | |
| » Starters: Cy Young vs Ed Siever | Eighth | 30 out |
| Wednesday, August 15 |
| » Lost to White Sox (62-43), 6-0 | Huntington Ave Baseball Grounds (13-39) | 31-74 | |
| » Starters: Ed Walsh vs Jesse Tannehill | Eighth | 31 out |
| Thursday, August 16 |
| » Lost to White Sox (63-43), 9-4 | Huntington Ave Baseball Grounds (13-40) | 31-75 | Lost 2 |
| » Starters: Roy Patterson vs Joe Harris | Eighth | 32 out |
| Friday, August 17 |
| » Lost to White Sox (64-43), 4-3 | Huntington Ave Baseball Grounds (13-41) | 31-76 | Lost 3 |
| » Starters: Frank Owen vs Cy Young | Eighth | 33 out |
| Saturday, August 18 |
| » Defeated Tigers (52-55), 8-4 | Huntington Ave Baseball Grounds (14-41) | 32-76 | |
| » Starters: Bill Donovan vs George Winter | Eighth | 33 out |
| Monday, August 20 |
| » Lost to Tigers (53-55), 6-4 | Huntington Ave Baseball Grounds (14-42) | 32-77 | |
| » Starters: George Mullin vs Ralph Glaze | Eighth | 34 out |
| Tuesday, August 21 |
| » Defeated Tigers (53-56), 5-2 | Huntington Ave Baseball Grounds (15-42) | 33-77 | |
| » Starters: Ed Siever vs Bill Dinneen | Eighth | 33½ out |
| Wednesday, August 22 |
| » Defeated Tigers (53-57), 3-2 | Huntington Ave Baseball Grounds (16-42) | 34-77 | Won 2 |
| » Starters: Red Donahue vs Cy Young | Eighth | 34 out |
| Thursday, August 23 |
| » Lost to Browns (58-52), 3-1 | Huntington Ave Baseball Grounds (16-43) | 34-78 | |
| » Starters: Jack Powell vs George Winter | Eighth | 35 out |
| Friday, August 24 |
| » Lost to Browns (59-52), 7-5 | Huntington Ave Baseball Grounds (16-44) | 34-79 | Lost 2 |
| » Starters: Fred Glade vs Joe Harris | Eighth | 35½ out |
| Saturday, August 25 |
| » Defeated Browns (59-53), 3-1 | Huntington Ave Baseball Grounds (17-44) | 35-79 | |
| » Starters: Harry Howell vs Jesse Tannehill | Eighth | 34 out |
| Monday, August 27 |
| » Lost to Indians (61-50), 6-5 | Huntington Ave Baseball Grounds (17-45) | 35-80 | |
| » Manager: Chick Stahl |
| » Starters: Bill Bernhard vs Bill Dinneen | Eighth | 35 out |
| Tuesday, August 28 |
| » Lost to Indians (62-50), 9-3 | Huntington Ave Baseball Grounds (17-46) | 35-81 | Lost 2 |
| » Starters: Bob Rhoads vs Bill Dinneen | Eighth | 35½ out |
| Wednesday, August 29 |
| » Defeated Indians (62-51), 6-2 | Huntington Ave Baseball Grounds (18-46) | 36-81 | |
| » Starters: Otto Hess vs Cy Young | Eighth | 34½ out |
| Thursday, August 30 |
| » Defeated Athletics (65-50), 3-2 | Huntington Ave Baseball Grounds (19-46) | 37-81 | Won 2 |
| » Starters: Jack Coombs vs George Winter | Eighth | 34 out |
| Friday, August 31 |
| » Defeated Athletics (65-51), 8-1 | Huntington Ave Baseball Grounds (20-46) | 38-81 | Won 3 |
| » Starters: Rube Waddell vs Ralph Glaze | Eighth | 34 out |
| Saturday, September 1 |
| » Lost to Athletics (66-51), 4-1 | Huntington Ave Baseball Grounds (20-47) | 38-82 | |
| » Starters: Jack Coombs vs Joe Harris | Eighth | 34 out |
| Monday, September 3 |
| » Defeated Senators (46-74), 3-1 | Huntington Ave Baseball Grounds (21-47) | 39-82 | |
| » Starters: Cy Falkenberg vs Cy Young | Eighth | 33½ out |
| » Lost to Senators (47-74), 6-3 | Huntington Ave Baseball Grounds (21-48) | 39-83 | |
| » Starters: Casey Patten vs George Winter | Eighth | 33½ out |
| Tuesday, September 4 |
| » Lost to Yankees (71-48), 7-0 | Huntington Ave Baseball Grounds (21-49) | 39-84 | Lost 2 |
| » Starters: Walter Clarkson vs Bill Dinneen | Eighth | 35 out |
| » Lost to Yankees (72-48), 1-0 | Huntington Ave Baseball Grounds (21-50) | 39-85 | Lost 3 |
| » Starters: Al Orth vs Ralph Glaze | Eighth | 35 out |
| Wednesday, September 5 |
| » Lost to Yankees (73-48), 6-1 | Huntington Ave Baseball Grounds (21-51) | 39-86 | Lost 4 |
| » Starters: Bill Hogg vs Cy Young | Eighth | 36 out |
| Thursday, September 6 |
| » Lost to Yankees (74-48), 6-5 | Hilltop Park (1-7) | 39-87 | Lost 5 |
| » Starters: George Winter vs Slow Joe Doyle | Eighth | 37 out |
| Friday, September 7 |
| » Defeated Senators (48-77), 4-1 | Huntington Ave Baseball Grounds (22-51) | 40-87 | |
| » Starters: Casey Patten vs Jesse Tannehill | Eighth | 37 out |
| Saturday, September 8 |
| » Lost to Senators (49-77), 5-2 | Huntington Ave Baseball Grounds (22-52) | 40-88 | |
| » Starters: Frank Kitson vs Ralph Glaze | Eighth | 38 out |
| Monday, September 10 |
| » Defeated Yankees (76-49), 4-1 | Hilltop Park (2-7) | 41-88 | |
| » Starters: George Winter vs Bill Hogg | Eighth | 37 out |
| Tuesday, September 11 |
| » Lost to Yankees (77-49), 11-3 | Hilltop Park (2-8) | 41-89 | |
| » Starters: Ed Barry vs Walter Clarkson | Eighth | 38 out |
| Wednesday, September 12 |
| » Defeated Yankees (77-50), 4-2 | Hilltop Park (3-8) | 42-89 | |
| » Starters: Ralph Glaze vs Al Orth | Eighth | 37 out |
| Thursday, September 13 |
| » Defeated Athletics (71-56), 4-3 | Columbia Park (4-5) | 43-89 | Won 2 |
| » Starters: Jesse Tannehill vs Eddie Plank | Eighth | 37 out |
| » Major-league debuts: Jack Cameron (Red Sox) |
| Friday, September 14 |
| » Lost to Athletics (72-56), 4-0 | Columbia Park (4-6) | 43-90 | |
| » Starters: Cy Young vs Rube Waddell | Eighth | 37½ out |
| Saturday, September 15 |
| » Lost to Athletics (73-56), 3-1 | Columbia Park (4-7) | 43-91 | Lost 2 |
| » Starters: George Winter vs Jack Coombs | Eighth | 39 out |
| » Lost to Athletics (74-56), 2-0 | Columbia Park (4-8) | 43-92 | Lost 3 |
| » Starters: Ed Barry vs Jimmy Dygert | Eighth | 39 out |
| Monday, September 17 |
| » Defeated Tigers (60-72), 7-2 | Bennett Park (5-4) | 44-92 | |
| » Starters: Jesse Tannehill vs Bill Donovan | Eighth | 39½ out |
| » Major-league debuts: Chet Chadbourne (Red Sox) |
| Tuesday, September 18 |
| » Defeated Tigers (60-73), 7-5 | Bennett Park (6-4) | 45-92 | Won 2 |
| » Starters: Ralph Glaze vs George Mullin | Eighth | 39½ out |
| Wednesday, September 19 |
| » Lost to Tigers (61-73), 9-2 | Bennett Park (6-5) | 45-93 | |
| » Starters: Ed Barry vs Ed Killian | Eighth | 39½ out |
| Thursday, September 20 |
| » Lost to Indians (77-58), 7-2 | League Park I (3-4) | 45-94 | Lost 2 |
| » Starters: Frank Oberlin vs Bob Rhoads | Eighth | 40½ out |
| » Lost to Indians (78-58), 4-3 | League Park I (3-5) | 45-95 | Lost 3 |
| » Starters: Jesse Tannehill vs Addie Joss | Eighth | 40½ out |
| Friday, September 21 |
| » Lost to Indians (79-58), 5-1 | League Park I (3-6) | 45-96 | Lost 4 |
| » Starters: George Winter vs Otto Hess | Eighth | 40 out |
| » Defeated Indians (79-59), 4-1 | League Park I (4-6) | 46-96 | |
| » Starters: Cy Young vs Happy Townsend | Eighth | 40 out |
| Saturday, September 22 |
| » Lost to Indians (80-59), 7-0 | League Park I (4-7) | 46-97 | |
| » Starters: Joe Harris vs Bill Bernhard | Eighth | 40½ out |
| Monday, September 24 |
| » Lost to White Sox (85-55), 4-1 | South Side Park III (1-8) | 46-98 | Lost 2 |
| » Starters: Jesse Tannehill vs Nick Altrock | Eighth | 41 out |
| Tuesday, September 25 |
| » Lost to White Sox (86-55), 3-2 | South Side Park III (1-9) | 46-99 | Lost 3 |
| » Starters: Jesse Tannehill vs Doc White | Eighth | 42 out |
| Wednesday, September 26 |
| » Lost to White Sox (87-55), 2-0 | South Side Park III (1-10) | 46-100 | Lost 4 |
| » Starters: Frank Oberlin vs Ed Walsh | Eighth | 43 out |
| Thursday, September 27 |
| » Lost to Browns (73-69), 9-3 | Sportsman's Park II (3-6) | 46-101 | Lost 5 |
| » Starters: Cy Young vs Beany Jacobson | Eighth | 44 out |
| Sunday, September 30 |
| » Lost to Browns (74-69), 7-1 | Sportsman's Park II (3-7) | 46-102 | Lost 6 |
| » Starters: Joe Harris vs Harry Howell | Eighth | 44 out |
| » Defeated Browns (74-70), 2-0 | Sportsman's Park II (4-7) | 47-102 | |
| » Starters: Rube Kroh vs Beany Jacobson | Eighth | 44 out |
| » Major-league debuts: Rube Kroh (Red Sox) |
| Tuesday, October 2 |
| » Defeated Senators (54-94), 6-5 | American League Park II (4-5) | 48-102 | Won 2 |
| » Starters: Frank Oberlin vs Clyde Goodwin | Eighth | 44½ out |
| Wednesday, October 3 |
| » Lost to Senators (55-94), 2-1 | American League Park II (4-6) | 48-103 | |
| » Starters: Joe Harris vs Cy Falkenberg | Eighth | 44½ out |
| » Defeated Senators (55-95), 2-1 | American League Park II (5-6) | 49-103 | |
| » Starters: Len Swormstedt vs Willy Wilson | Eighth | 44½ out |
| Friday, October 5 |
| » Lost to Yankees (88-61), 6-4 | Huntington Ave Baseball Grounds (22-53) | 49-104 | |
| » Starters: Al Orth vs Frank Oberlin | Eighth | 46 out |
| Saturday, October 6 |
| » Lost to Yankees (89-61), 5-4 | Huntington Ave Baseball Grounds (22-54) | 49-105 | Lost 2 |
| » Starters: Tom Hughes vs Len Swormstedt | Eighth | 46 out |
| Thursday, October 11 |
| Future Red Sox Tom Carey is born in Hoboken, NJ. |
| Friday, October 12 |
| Future Red Sox Joe Cronin is born in San Francisco, CA. |
| Thursday, November 15 |
| Future Red Sox Gene Rye is born in Chicago, IL. |
| Sunday, December 2 |
| Future Red Sox Johnny Welch is born in Washington, DC. |
Game information provided by Retrosheet (www.retrosheet.org) |