| Friday, April 14 |
| » Defeated Senators (0-1), 4-2 | American League Park II (1-0) | 1-0 | |
| » Starters: Jack Chesbro vs Casey Patten | First | -- |
| » Major-league debuts: Hal Chase (Yankees) |
| Saturday, April 15 |
| » Defeated Senators (0-2), 4-0 | American League Park II (2-0) | 2-0 | Won 2 |
| » Starters: Al Orth vs Tom Hughes | First | -- |
| Sunday, April 16 |
| » Major-league debuts: Jim Buchanan (Browns) |
| Monday, April 17 |
| » Defeated Senators (0-3), 13-7 | American League Park II (3-0) | 3-0 | Won 3 |
| » Starters: Ambrose Puttmann vs Happy Townsend | First | -- |
| » Major-league debuts: Shag Shaughnessy (Senators) |
| Wednesday, April 19 |
| » Lost to Athletics (3-0), 7-6 | Columbia Park (0-1) | 3-1 | |
| » Starters: Jack Chesbro vs Eddie Plank | Second | ½ out |
| Thursday, April 20 |
| » Lost to Athletics (4-0), 8-1 | Columbia Park (0-2) | 3-2 | Lost 2 |
| » Starters: Jack Powell vs Chief Bender | Second | 1½ out |
| Saturday, April 22 |
| » Defeated Senators (3-4), 5-3 | Hilltop Park (1-0) | 4-2 | |
| » Starters: Barney Wolfe vs Walter Clarkson | Second | 1 out |
| Monday, April 24 |
| » Lost to Senators (4-4), 4-3 | Hilltop Park (1-1) | 4-3 | |
| » Starters: Casey Patten vs Ambrose Puttmann | Third | 1 out |
| Tuesday, April 25 |
| » Defeated Senators (4-5), 6-5 | Hilltop Park (2-1) | 5-3 | |
| » Starters: Tom Hughes vs Walter Clarkson | Third | 1 out |
| » Major-league debuts: Bill Hogg (Yankees) |
| Wednesday, April 26 |
| » Defeated Athletics (6-3), 4-3 | Hilltop Park (3-1) | 6-3 | Won 2 |
| » Starters: Andy Coakley vs Jack Chesbro | Second | 1 out |
| Thursday, April 27 |
| » Defeated Athletics (6-4), 1-0 | Hilltop Park (4-1) | 7-3 | Won 3 |
| » Starters: Eddie Plank vs Clark Griffith | First | -- |
| Friday, April 28 |
| » Lost to Athletics (7-4), 7-5 | Hilltop Park (4-2) | 7-4 | |
| » Starters: Chief Bender vs Al Orth | First | -- |
| Monday, May 1 |
| » Lost to Red Sox (4-10), 4-3 | Hilltop Park (4-3) | 7-5 | Lost 2 |
| » Starters: Cy Young vs Bill Hogg | First | -- |
| Tuesday, May 2 |
| » Lost to Red Sox (5-10), 9-4 | Hilltop Park (4-4) | 7-6 | Lost 3 |
| » Starters: George Winter vs Ambrose Puttmann | Third | 1 out |
| Wednesday, May 3 |
| » Defeated Red Sox (5-11), 3-2 | Hilltop Park (5-4) | 8-6 | |
| » Starters: Jesse Tannehill vs Jack Chesbro | Second | 1 out |
| Thursday, May 4 |
| » Lost to Red Sox (6-11), 9-4 | Hilltop Park (5-5) | 8-7 | |
| » Starters: Norwood Gibson vs Al Orth | Third | 1 out |
| Friday, May 5 |
| » Lost to Red Sox (7-11), 4-2 | Huntington Ave Baseball Grounds (0-1) | 8-8 | Lost 2 |
| » Starters: Jack Powell vs George Winter | Third | 2 out |
| Saturday, May 6 |
| » Lost to Red Sox (8-11), 8-2 | Huntington Ave Baseball Grounds (0-2) | 8-9 | Lost 3 |
| » Starters: Jack Chesbro vs Bill Dinneen | Fifth | 2 out |
| Monday, May 8 |
| » Defeated Red Sox (8-12), 9-3 | Huntington Ave Baseball Grounds (1-2) | 9-9 | |
| » Starters: Al Orth vs Cy Young | Fourth | 1½ out |
| Tuesday, May 9 |
| » Lost to Red Sox (9-12), 5-2 | Huntington Ave Baseball Grounds (1-3) | 9-10 | |
| » Starters: Jack Powell vs Jesse Tannehill | Fourth | 2 out |
| Friday, May 12 |
| » Defeated White Sox (10-10), 7-3 | South Side Park III (1-0) | 10-10 | |
| » Starters: Al Orth vs Doc White | Third | 1½ out |
| Saturday, May 13 |
| » Tied White Sox, 0-0 | South Side Park III (1-0) | 10-10 | |
| » Starters: Bill Hogg vs Frank Smith | Third | 2 out |
| Sunday, May 14 |
| » Lost to White Sox (11-10), 9-3 | South Side Park III (1-1) | 10-11 | |
| » Starters: Ambrose Puttmann vs Nick Altrock | Fifth | 2½ out |
| Monday, May 15 |
| » Lost to White Sox (12-10), 10-4 | South Side Park III (1-2) | 10-12 | Lost 2 |
| » Starters: Al Orth vs Ed Walsh | Fifth | 2½ out |
| Tuesday, May 16 |
| » Defeated Browns (10-13), 3-2 | Sportsman's Park II (1-0) | 11-12 | |
| » Starters: Jack Powell vs Harry Howell | Fourth | 2 out |
| Wednesday, May 17 |
| » Lost to Browns (11-13), 10-2 | Sportsman's Park II (1-1) | 11-13 | |
| » Starters: Bill Hogg vs Barney Pelty | Fifth | 2½ out |
| Thursday, May 18 |
| » Lost to Browns (12-13), 3-1 | Sportsman's Park II (1-2) | 11-14 | Lost 2 |
| » Starters: Bill Hogg vs Willie Sudhoff | Seventh | 3 out |
| Future Yankee Arndt Jorgens is born in Modum, Norway. |
| Friday, May 19 |
| » Defeated Browns (12-14), 3-0 | Sportsman's Park II (2-2) | 12-14 | |
| » Starters: Jack Powell vs Harry Howell | Fifth | 3 out |
| Saturday, May 20 |
| » Lost to Tigers (13-12), 6-0 | Bennett Park (0-1) | 12-15 | |
| » Starters: Al Orth vs Bill Donovan | Sixth | 4 out |
| Monday, May 22 |
| » Defeated Tigers (13-13), 3-0 | Bennett Park (1-1) | 13-15 | |
| » Starters: Clark Griffith vs George Mullin | Sixth | 3 out |
| Tuesday, May 23 |
| » Lost to Tigers (14-13), 5-4 | Bennett Park (1-2) | 13-16 | |
| » Starters: Clark Griffith vs Ed Killian | Sixth | 4 out |
| Wednesday, May 24 |
| » Lost to Tigers (15-13), 12-6 | Bennett Park (1-3) | 13-17 | Lost 2 |
| » Starters: Jack Powell vs Frank Kitson | Sixth | 5 out |
| Thursday, May 25 |
| » Lost to Indians (16-11), 9-1 | League Park I (0-1) | 13-18 | Lost 3 |
| » Starters: Jack Powell vs Addie Joss | Seventh | 5½ out |
| Friday, May 26 |
| » Lost to Indians (17-11), 1-0 | League Park I (0-2) | 13-19 | Lost 4 |
| » Starters: Al Orth vs Otto Hess | Seventh | 6½ out |
| Saturday, May 27 |
| » Lost to Indians (18-11), 6-3 | League Park I (0-3) | 13-20 | Lost 5 |
| » Starters: Bill Hogg vs Earl Moore | Seventh | 7½ out |
| Monday, May 29 |
| » Lost to Athletics (18-14), 2-1 | Columbia Park (0-3) | 13-21 | Lost 6 |
| » Starters: Al Orth vs Rube Waddell | Eighth | 8 out |
| Tuesday, May 30 |
| » Lost to Athletics (19-14), 6-5 | Columbia Park (0-4) | 13-22 | Lost 7 |
| » Starters: Jack Powell vs Andy Coakley | Eighth | 9½ out |
| Wednesday, May 31 |
| » Defeated Athletics (19-15), 8-3 | Columbia Park (1-4) | 14-22 | |
| » Starters: Bill Hogg vs Chief Bender | Eighth | 9½ out |
| Thursday, June 1 |
| » Defeated Red Sox (15-20), 15-5 | Hilltop Park (6-5) | 15-22 | Won 2 |
| » Starters: Bill Dinneen vs Jack Chesbro | Seventh | 8½ out |
| Saturday, June 3 |
| » Lost to Red Sox (16-20), 10-3 | Hilltop Park (6-6) | 15-23 | |
| » Starters: Jesse Tannehill vs Al Orth | Seventh | 9½ out |
| Monday, June 5 |
| » Defeated Red Sox (16-21), 5-2 | Hilltop Park (7-6) | 16-23 | |
| » Starters: Cy Young vs Bill Hogg | Seventh | 9½ out |
| Thursday, June 8 |
| » Lost to Indians (25-12), 4-0 | Hilltop Park (7-7) | 16-24 | |
| » Starters: Earl Moore vs Jack Chesbro | Seventh | 10½ out |
| Friday, June 9 |
| » Lost to Indians (26-12), 4-2 | Hilltop Park (7-8) | 16-25 | Lost 2 |
| » Starters: Addie Joss vs Al Orth | Sixth | 11½ out |
| Saturday, June 10 |
| » Defeated Browns (17-28), 9-3 | Hilltop Park (8-8) | 17-25 | |
| » Starters: Willie Sudhoff vs Jack Powell | Sixth | 10½ out |
| Future Yankee Danny MacFayden is born in North Truro, MA. |
| Wednesday, June 14 |
| » Defeated Browns (17-29), 7-5 | Hilltop Park (9-8) | 18-25 | Won 2 |
| » Starters: Barney Pelty vs Jack Powell | Sixth | 10 out |
| Thursday, June 15 |
| » Lost to White Sox (28-19), 5-1 | Hilltop Park (9-9) | 18-26 | |
| » Starters: Doc White vs Jack Chesbro | Sixth | 11 out |
| Friday, June 16 |
| » Defeated White Sox (28-20), 3-0 | Hilltop Park (10-9) | 19-26 | |
| » Starters: Nick Altrock vs Al Orth | Sixth | 11 out |
| Saturday, June 17 |
| » Lost to White Sox (29-20), 6-3 | Hilltop Park (10-10) | 19-27 | |
| » Starters: Frank Owen vs Bill Hogg | Sixth | 12 out |
| Monday, June 19 |
| » Lost to White Sox (30-20), 9-6 | Hilltop Park (10-11) | 19-28 | Lost 2 |
| » Starters: Doc White vs Jack Chesbro | Sixth | 13 out |
| Tuesday, June 20 |
| » Lost to Tigers (27-23), 5-3 | Hilltop Park (10-12) | 19-29 | Lost 3 |
| » Starters: Frank Kitson vs Al Orth | Sixth | 14 out |
| Friday, June 23 |
| » Defeated Tigers (27-24), 7-0 | Hilltop Park (11-12) | 20-29 | |
| » Starters: George Mullin vs Jack Chesbro | Sixth | 12 out |
| Saturday, June 24 |
| » Lost to Red Sox (23-26), 3-0 | Huntington Ave Baseball Grounds (1-4) | 20-30 | |
| » Starters: Bill Hogg vs Jesse Tannehill | Sixth | 12 out |
| Wednesday, June 28 |
| » Defeated Red Sox (23-27), 5-2 | Huntington Ave Baseball Grounds (2-4) | 21-30 | |
| » Starters: Jack Chesbro vs Bill Dinneen | Sixth | 11½ out |
| » Defeated Red Sox (23-28), 3-1 | Huntington Ave Baseball Grounds (3-4) | 22-30 | Won 2 |
| » Starters: Jack Chesbro vs George Winter | Sixth | 11½ out |
| Thursday, June 29 |
| » Defeated Athletics (33-23), 13-4 | Hilltop Park (12-12) | 23-30 | Won 3 |
| » Starters: Chief Bender vs Al Orth | Fifth | 10½ out |
| Friday, June 30 |
| » Lost to Athletics (34-23), 7-4 | Hilltop Park (12-13) | 23-31 | |
| » Starters: Eddie Plank vs Bill Hogg | Sixth | 11½ out |
| Saturday, July 1 |
| » Lost to Athletics (35-23), 1-0 | Hilltop Park (12-14) | 23-32 | Lost 2 |
| » Starters: Andy Coakley vs Jack Chesbro | Fifth | 13 out |
| » Lost to Athletics (36-23), 3-2 | Hilltop Park (12-15) | 23-33 | Lost 3 |
| » Starters: Rube Waddell vs Bill Hogg | Fifth | 13 out |
| Monday, July 3 |
| » Defeated Athletics (36-24), 3-0 | Hilltop Park (13-15) | 24-33 | |
| » Starters: Weldon Henley vs Al Orth | Fifth | 13 out |
| Tuesday, July 4 |
| » Defeated Senators (22-39), 8-5 | Hilltop Park (14-15) | 25-33 | Won 2 |
| » Starters: Tom Hughes vs Jack Powell | Fifth | 12 out |
| » Defeated Senators (22-40), 3-2 | Hilltop Park (15-15) | 26-33 | Won 3 |
| » Starters: Barney Wolfe vs Jack Chesbro | Fifth | 12 out |
| Wednesday, July 5 |
| » Lost to Senators (23-40), 8-1 | Hilltop Park (15-16) | 26-34 | |
| » Starters: Casey Patten vs Bill Hogg | Sixth | 13 out |
| Friday, July 7 |
| » Defeated Senators (23-41), 3-0 | American League Park II (4-0) | 27-34 | |
| » Starters: Al Orth vs Happy Townsend | Sixth | 12 out |
| » Defeated Senators (23-42), 5-1 | American League Park II (5-0) | 28-34 | Won 2 |
| » Starters: Jack Powell vs Tom Hughes | Sixth | 12 out |
| Saturday, July 8 |
| » Defeated Senators (23-43), 6-4 | American League Park II (6-0) | 29-34 | Won 3 |
| » Starters: Jack Chesbro vs Barney Wolfe | Sixth | 11½ out |
| » Tied Senators, 5-5 | American League Park II (6-0) | 29-34 | |
| » Starters: Bill Hogg vs Casey Patten | Sixth | 11½ out |
| Monday, July 10 |
| » Defeated Tigers (33-35), 3-0 | Bennett Park (2-3) | 30-34 | Won 4 |
| » Starters: Jack Chesbro vs Ed Killian | Fourth | 10½ out |
| Tuesday, July 11 |
| » Lost to Tigers (34-35), 3-1 | Bennett Park (2-4) | 30-35 | |
| » Starters: Jack Powell vs Bill Donovan | Sixth | 11 out |
| Wednesday, July 12 |
| » Defeated Tigers (34-36), 7-0 | Bennett Park (3-4) | 31-35 | |
| » Starters: Bill Hogg vs Frank Kitson | Fifth | 10½ out |
| Thursday, July 13 |
| » Lost to Tigers (35-36), 6-3 | Bennett Park (3-5) | 31-36 | |
| » Starters: Jack Chesbro vs George Mullin | Sixth | 11½ out |
| Friday, July 14 |
| » Lost to Indians (45-26), 7-2 | League Park I (0-4) | 31-37 | Lost 2 |
| » Starters: Jack Powell vs Addie Joss | Sixth | 12½ out |
| Saturday, July 15 |
| » Defeated Indians (45-27), 6-5 | League Park I (1-4) | 32-37 | |
| » Starters: Jack Chesbro vs Earl Moore | Sixth | 11½ out |
| Monday, July 17 |
| » Lost to Indians (46-27), 4-1 | League Park I (1-5) | 32-38 | |
| » Starters: Bill Hogg vs Bill Bernhard | Sixth | 12½ out |
| Tuesday, July 18 |
| » Defeated Indians (46-28), 2-0 | League Park I (2-5) | 33-38 | |
| » Starters: Al Orth vs Red Donahue | Sixth | 11½ out |
| Wednesday, July 19 |
| » Defeated White Sox (44-30), 2-1 | South Side Park III (2-2) | 34-38 | Won 2 |
| » Starters: Jack Chesbro vs Doc White | Fifth | 12 out |
| Thursday, July 20 |
| » Lost to White Sox (45-30), 6-4 | South Side Park III (2-3) | 34-39 | |
| » Starters: Bill Hogg vs Frank Owen | Fourth | 13½ out |
| Friday, July 21 |
| » Lost to White Sox (46-30), 2-1 | South Side Park III (2-4) | 34-40 | Lost 2 |
| » Starters: Al Orth vs Nick Altrock | Sixth | 13½ out |
| Saturday, July 22 |
| » Lost to White Sox (47-30), 2-1 | South Side Park III (2-5) | 34-41 | Lost 3 |
| » Starters: Jack Chesbro vs Doc White | Sixth | 14½ out |
| Sunday, July 23 |
| » Defeated Browns (31-50), 5-2 | Sportsman's Park II (3-2) | 35-41 | |
| » Starters: Jack Powell vs Willie Sudhoff | Sixth | 14 out |
| » Major-league debuts: Tubby Spencer (Browns) |
| Monday, July 24 |
| » Defeated Browns (31-51), 10-5 | Sportsman's Park II (4-2) | 36-41 | Won 2 |
| » Starters: Jack Chesbro vs Jim Buchanan | Sixth | 14 out |
| Tuesday, July 25 |
| » Defeated Browns (31-52), 10-4 | Sportsman's Park II (5-2) | 37-41 | Won 3 |
| » Starters: Al Orth vs Barney Pelty | Fifth | 13 out |
| Thursday, July 27 |
| Future Yankee Leo Durocher is born in West Springfield, MA. |
| Saturday, July 29 |
| » Defeated Indians (53-34), 7-0 | Hilltop Park (16-16) | 38-41 | Won 4 |
| » Starters: Bill Bernhard vs Jack Chesbro | Fifth | 10 out |
| » Defeated Indians (53-35), 10-9 | Hilltop Park (17-16) | 39-41 | Won 5 |
| » Starters: Bob Rhoads vs Al Orth | Fifth | 10 out |
| Tuesday, August 1 |
| » Defeated Indians (53-36), 3-2 | Hilltop Park (18-16) | 40-41 | Won 6 |
| » Starters: Earl Moore vs Al Orth | Fourth | 9 out |
| Wednesday, August 2 |
| » Defeated Indians (53-37), 4-3 | Hilltop Park (19-16) | 41-41 | Won 7 |
| » Starters: Red Donahue vs Jack Chesbro | Fourth | 8 out |
| Thursday, August 3 |
| » Defeated Browns (32-55), 5-4 | Hilltop Park (20-16) | 42-41 | Won 8 |
| » Starters: Fred Glade vs Jack Powell | Fourth | 8 out |
| Friday, August 4 |
| » Defeated Browns (32-56), 7-3 | Hilltop Park (21-16) | 43-41 | Won 9 |
| » Starters: Harry Howell vs Doc Newton | Fourth | 7½ out |
| Saturday, August 5 |
| » Defeated Browns (32-57), 3-1 | Hilltop Park (22-16) | 44-41 | Won 10 |
| » Starters: Willie Sudhoff vs Jack Chesbro | Fourth | 7 out |
| » Defeated Browns (32-58), 6-5 | Hilltop Park (23-16) | 45-41 | Won 11 |
| » Starters: Barney Pelty vs Al Orth | Fourth | 7 out |
| Monday, August 7 |
| » Defeated Browns (32-59), 14-4 | Hilltop Park (24-16) | 46-41 | Won 12 |
| » Starters: Willie Sudhoff vs Jack Powell | Fourth | 6 out |
| Thursday, August 10 |
| » Lost to White Sox (52-38), 8-2 | Hilltop Park (24-17) | 46-42 | |
| » Starters: Frank Smith vs Jack Chesbro | Fourth | 6 out |
| Friday, August 11 |
| » Defeated White Sox (52-39), 2-1 | Hilltop Park (25-17) | 47-42 | |
| » Starters: Doc White vs Al Orth | Fourth | 6 out |
| Saturday, August 12 |
| » Defeated Tigers (46-52), 2-1 | Hilltop Park (26-17) | 48-42 | Won 2 |
| » Starters: Bill Donovan vs Jack Chesbro | Fourth | 6½ out |
| » Lost to Tigers (47-52), 2-1 | Hilltop Park (26-18) | 48-43 | |
| » Starters: George Mullin vs Jack Powell | Fourth | 6½ out |
| Monday, August 14 |
| » Defeated Tigers (47-53), 7-1 | Hilltop Park (27-18) | 49-43 | |
| » Starters: Charlie Jackson vs Doc Newton | Fourth | 6½ out |
| Tuesday, August 15 |
| » Lost to Tigers (48-53), 6-4 | Hilltop Park (27-19) | 49-44 | |
| » Starters: Ed Killian vs Al Orth | Fourth | 7½ out |
| Thursday, August 17 |
| » Defeated Indians (57-43), 2-1 | League Park I (3-5) | 50-44 | |
| » Starters: Jack Chesbro vs Addie Joss | Fourth | 8 out |
| Friday, August 18 |
| » Lost to White Sox (54-40), 6-0 | South Side Park III (2-6) | 50-45 | |
| » Starters: Al Orth vs Doc White | Fourth | 8½ out |
| » Major-league debuts: Wilbur Good (Yankees) |
| Saturday, August 19 |
| » Defeated White Sox (54-41), 4-2 | South Side Park III (3-6) | 51-45 | |
| » Starters: Doc Newton vs Frank Smith | Fourth | 7½ out |
| Sunday, August 20 |
| » Lost to White Sox (55-41), 2-1 | South Side Park III (3-7) | 51-46 | |
| » Starters: Al Orth vs Doc White | Fourth | 7 out |
| Monday, August 21 |
| » Defeated White Sox (55-42), 5-3 | South Side Park III (4-7) | 52-46 | |
| » Starters: Jack Chesbro vs Frank Smith | Fourth | 7 out |
| Wednesday, August 23 |
| » Lost to Browns (38-66), 5-0 | Sportsman's Park II (5-3) | 52-47 | |
| » Starters: Jack Powell vs Fred Glade | Fourth | 7 out |
| » Defeated Browns (38-67), 1-0 | Sportsman's Park II (6-3) | 53-47 | |
| » Starters: Doc Newton vs Harry Howell | Fourth | 7 out |
| » Major-league debuts: Frank Delahanty (Yankees) |
| Thursday, August 24 |
| » Lost to Browns (39-67), 2-1 | Sportsman's Park II (6-4) | 53-48 | |
| » Starters: Al Orth vs Barney Pelty | Fourth | 7 out |
| » Defeated Browns (39-68), 3-1 | Sportsman's Park II (7-4) | 54-48 | |
| » Starters: Jack Powell vs Willie Sudhoff | Fourth | 7 out |
| Friday, August 25 |
| » Defeated Indians (59-49), 3-1 | League Park I (4-5) | 55-48 | Won 2 |
| » Starters: Jack Chesbro vs Red Donahue | Fourth | 7 out |
| Saturday, August 26 |
| » Lost to Indians (60-49), 1-0 | League Park I (4-6) | 55-49 | |
| » Starters: Jack Powell vs Addie Joss | Fourth | 7 out |
| Monday, August 28 |
| » Lost to Indians (61-49), 5-4 | League Park I (4-7) | 55-50 | Lost 2 |
| » Starters: Al Orth vs Otto Hess | Fourth | 8 out |
| Tuesday, August 29 |
| » Lost to Tigers (52-60), 2-0 | Bennett Park (3-6) | 55-51 | Lost 3 |
| » Starters: Doc Newton vs Ed Killian | Fourth | 9½ out |
| Wednesday, August 30 |
| » Lost to Tigers (53-60), 5-3 | Bennett Park (3-7) | 55-52 | Lost 4 |
| » Starters: Jack Chesbro vs George Mullin | Fourth | 10½ out |
| » Major-league debuts: Ty Cobb (Tigers) |
| Thursday, August 31 |
| » Lost to Tigers (54-60), 5-0 | Bennett Park (3-8) | 55-53 | Lost 5 |
| » Starters: Jack Powell vs Bill Donovan | Fifth | 11½ out |
| » Major-league debuts: Ed Hahn (Yankees) |
| Saturday, September 2 |
| » Defeated Red Sox (56-55), 1-0 | Hilltop Park (28-19) | 56-53 | |
| » Starters: George Winter vs Al Orth | Fourth | 11 out |
| Sunday, September 3 |
| » Major-league debuts: Eddie Cicotte (Tigers) |
| Monday, September 4 |
| » Lost to Red Sox (57-55), 9-4 | Hilltop Park (28-20) | 56-54 | |
| » Starters: Ed Barry vs Jack Chesbro | Fourth | 12 out |
| » Defeated Red Sox (57-56), 8-5 | Hilltop Park (29-20) | 57-54 | |
| » Starters: Norwood Gibson vs Jack Powell | Fourth | 12 out |
| Tuesday, September 5 |
| » Defeated Senators (47-68), 6-4 | American League Park II (7-0) | 58-54 | Won 2 |
| » Starters: Jack Chesbro vs Tom Hughes | Fourth | 11 out |
| Wednesday, September 6 |
| » Defeated Senators (47-69), 2-0 | American League Park II (8-0) | 59-54 | Won 3 |
| » Starters: Clark Griffith vs Rick Adams | Fourth | 11 out |
| Thursday, September 7 |
| » Lost to Senators (48-69), 11-6 | American League Park II (8-1) | 59-55 | |
| » Starters: Al Orth vs Casey Patten | Fourth | 12½ out |
| » Lost to Senators (49-69), 10-2 | American League Park II (8-2) | 59-56 | Lost 2 |
| » Starters: Wilbur Good vs Happy Townsend | Fourth | 12½ out |
| Friday, September 8 |
| » Lost to Senators (50-69), 6-5 | American League Park II (8-3) | 59-57 | Lost 3 |
| » Starters: Jack Chesbro vs Beany Jacobson | Fourth | 13½ out |
| Saturday, September 9 |
| » Lost to Athletics (75-45), 6-2 | Columbia Park (1-5) | 59-58 | Lost 4 |
| » Starters: Clark Griffith vs Eddie Plank | Fourth | 14½ out |
| » Tied Athletics, 7-7 | Columbia Park (1-5) | 59-58 | |
| » Starters: Bill Hogg vs Chief Bender | Fourth | 14½ out |
| Tuesday, September 12 |
| » Lost to Athletics (76-45), 4-3 | Columbia Park (1-6) | 59-59 | Lost 5 |
| » Starters: Jack Chesbro vs Andy Coakley | Fourth | 14½ out |
| » Defeated Athletics (76-46), 7-4 | Columbia Park (2-6) | 60-59 | |
| » Starters: Al Orth vs Jimmy Dygert | Fourth | 14½ out |
| Wednesday, September 13 |
| » Defeated Senators (51-72), 6-1 | Hilltop Park (30-20) | 61-59 | Won 2 |
| » Starters: Happy Townsend vs Al Orth | Fourth | 14½ out |
| Thursday, September 14 |
| » Defeated Senators (51-73), 7-6 | Hilltop Park (31-20) | 62-59 | Won 3 |
| » Starters: Rick Adams vs Bill Hogg | Fourth | 13½ out |
| Friday, September 15 |
| » Lost to Senators (52-73), 6-2 | Hilltop Park (31-21) | 62-60 | |
| » Starters: Cy Falkenberg vs Jack Chesbro | Fourth | 14 out |
| Saturday, September 16 |
| » Defeated Senators (52-74), 5-2 | Hilltop Park (32-21) | 63-60 | |
| » Starters: Barney Wolfe vs Al Orth | Fourth | 14½ out |
| » Lost to Senators (53-74), 3-0 | Hilltop Park (32-22) | 63-61 | |
| » Starters: Casey Patten vs Clark Griffith | Fourth | 14½ out |
| Tuesday, September 19 |
| » Defeated Athletics (79-49), 5-0 | Hilltop Park (33-22) | 64-61 | |
| » Starters: Andy Coakley vs Ambrose Puttmann | Fourth | 14½ out |
| » Lost to Athletics (80-49), 3-0 | Hilltop Park (33-23) | 64-62 | |
| » Starters: Chief Bender vs Wilbur Good | Fourth | 14½ out |
| Wednesday, September 20 |
| » Defeated Athletics (80-50), 1-0 | Hilltop Park (34-23) | 65-62 | |
| » Starters: Weldon Henley vs Bill Hogg | Fourth | 13½ out |
| Thursday, September 21 |
| » Lost to White Sox (79-53), 3-2 | Hilltop Park (34-24) | 65-63 | |
| » Starters: Doc White vs Jack Chesbro | Sixth | 15 out |
| » Lost to White Sox (80-53), 6-2 | Hilltop Park (34-25) | 65-64 | Lost 2 |
| » Starters: Frank Smith vs Al Orth | Sixth | 15 out |
| Friday, September 22 |
| » Defeated White Sox (80-54), 5-2 | Hilltop Park (35-25) | 66-64 | |
| » Starters: Nick Altrock vs Louis LeRoy | Fourth | 14½ out |
| Saturday, September 23 |
| » Lost to White Sox (81-54), 3-1 | Hilltop Park (35-26) | 66-65 | |
| » Starters: Frank Owen vs Ambrose Puttmann | Fifth | 16½ out |
| » Lost to White Sox (82-54), 10-1 | Hilltop Park (35-27) | 66-66 | Lost 2 |
| » Starters: Frank Smith vs Bill Hogg | Fifth | 16½ out |
| Monday, September 25 |
| » Defeated Browns (48-91), 13-10 | Hilltop Park (36-27) | 67-66 | |
| » Starters: Cy Morgan vs Al Orth | Fifth | 16½ out |
| Tuesday, September 26 |
| » Lost to Browns (49-91), 6-3 | Hilltop Park (36-28) | 67-67 | |
| » Starters: Jack Powell vs Doc Newton | Fifth | 17 out |
| » Lost to Browns (50-91), 7-2 | Hilltop Park (36-29) | 67-68 | Lost 2 |
| » Starters: Jim Buchanan vs Louis LeRoy | Fifth | 17 out |
| Wednesday, September 27 |
| » Lost to Browns (51-91), 7-2 | Hilltop Park (36-30) | 67-69 | Lost 3 |
| » Starters: Harry Howell vs Ambrose Puttmann | Sixth | 17 out |
| Thursday, September 28 |
| » Defeated Indians (72-72), 9-4 | Hilltop Park (37-30) | 68-69 | |
| » Starters: Otto Hess vs Jack Chesbro | Fifth | 17½ out |
| » Lost to Indians (73-72), 3-1 | Hilltop Park (37-31) | 68-70 | |
| » Starters: Addie Joss vs Al Orth | Fifth | 17½ out |
| Friday, September 29 |
| » Lost to Indians (74-72), 1-0 | Hilltop Park (37-32) | 68-71 | Lost 2 |
| » Starters: Bob Rhoads vs Walter Clarkson | Sixth | 18½ out |
| » Major-league debuts: Frank LaPorte (Yankees) |
| Saturday, September 30 |
| » Defeated Indians (74-73), 7-5 | Hilltop Park (38-32) | 69-71 | |
| » Starters: Bill Bernhard vs Louis LeRoy | Sixth | 18 out |
| » Lost to Indians (75-73), 1-0 | Hilltop Park (38-33) | 69-72 | |
| » Starters: Hi West vs Ambrose Puttmann | Sixth | 18 out |
| Future Yankee Johnny Allen is born in Lenoir, NC. |
| Monday, October 2 |
| » Lost to Tigers (76-71), 7-2 | Hilltop Park (38-34) | 69-73 | Lost 2 |
| » Starters: Bill Donovan vs Jack Chesbro | Sixth | 19½ out |
| » Lost to Tigers (77-71), 7-1 | Hilltop Park (38-35) | 69-74 | Lost 3 |
| » Starters: John Eubank vs Bill Hogg | Sixth | 19½ out |
| » Major-league debuts: Rube Oldring (Yankees) |
| Tuesday, October 3 |
| » Defeated Tigers (77-72), 3-0 | Hilltop Park (39-35) | 70-74 | |
| » Starters: George Mullin vs Al Orth | Sixth | 19 out |
| » Defeated Tigers (77-73), 10-1 | Hilltop Park (40-35) | 71-74 | Won 2 |
| » Starters: Jimmy Wiggs vs Clark Griffith | Sixth | 19 out |
| Thursday, October 5 |
| » Lost to Red Sox (75-74), 10-5 | Huntington Ave Baseball Grounds (3-5) | 71-75 | |
| » Starters: Ambrose Puttmann vs Cy Young | Sixth | 21 out |
| Friday, October 6 |
| » Lost to Red Sox (76-74), 3-1 | Huntington Ave Baseball Grounds (3-6) | 71-76 | Lost 2 |
| » Starters: Walter Clarkson vs Norwood Gibson | Sixth | 21 out |
| Saturday, October 7 |
| » Lost to Red Sox (77-74), 7-6 | Huntington Ave Baseball Grounds (3-7) | 71-77 | Lost 3 |
| » Starters: Bill Hogg vs Jesse Tannehill | Sixth | 21½ out |
| » Lost to Red Sox (78-74), 12-9 | Huntington Ave Baseball Grounds (3-8) | 71-78 | Lost 4 |
| » Starters: Doc Newton vs Ed Hughes | Sixth | 21½ out |
Game information provided by Retrosheet (www.retrosheet.org) |