| Friday, April 14 |
| » Defeated Red Sox (0-1), 3-2 | Columbia Park (1-0) | 1-0 | |
| » Starters: Cy Young vs Chief Bender | First | -- |
| Saturday, April 15 |
| » Defeated Red Sox (0-2), 6-5 | Columbia Park (2-0) | 2-0 | Won 2 |
| » Starters: Jesse Tannehill vs Andy Coakley | First | -- |
| » Major-league debuts: Harry Barton (Athletics) |
| Sunday, April 16 |
| » Major-league debuts: Jim Buchanan (Browns) |
| Wednesday, April 19 |
| » Defeated Yankees (3-1), 7-6 | Columbia Park (3-0) | 3-0 | Won 3 |
| » Starters: Jack Chesbro vs Eddie Plank | First | -- |
| Thursday, April 20 |
| » Defeated Yankees (3-2), 8-1 | Columbia Park (4-0) | 4-0 | Won 4 |
| » Starters: Jack Powell vs Chief Bender | First | -- |
| Friday, April 21 |
| » Defeated Red Sox (0-6), 5-4 | Huntington Ave Baseball Grounds (1-0) | 5-0 | Won 5 |
| » Starters: Andy Coakley vs Norwood Gibson | First | -- |
| Saturday, April 22 |
| » Lost to Red Sox (1-6), 3-0 | Huntington Ave Baseball Grounds (1-1) | 5-1 | |
| » Starters: Weldon Henley vs George Winter | First | -- |
| Monday, April 24 |
| » Lost to Red Sox (2-6), 3-1 | Huntington Ave Baseball Grounds (1-2) | 5-2 | Lost 2 |
| » Starters: Eddie Plank vs Jesse Tannehill | Second | 1 out |
| Tuesday, April 25 |
| » Defeated Red Sox (2-7), 10-6 | Huntington Ave Baseball Grounds (2-2) | 6-2 | |
| » Starters: Chief Bender vs Bill Dinneen | First | -- |
| » Major-league debuts: Myron Grimshaw (Red Sox) |
| Wednesday, April 26 |
| » Lost to Yankees (6-3), 4-3 | Hilltop Park (0-1) | 6-3 | |
| » Starters: Andy Coakley vs Jack Chesbro | Second | 1 out |
| Thursday, April 27 |
| » Lost to Yankees (7-3), 1-0 | Hilltop Park (0-2) | 6-4 | Lost 2 |
| » Starters: Eddie Plank vs Clark Griffith | Third | 1 out |
| Friday, April 28 |
| » Defeated Yankees (7-4), 7-5 | Hilltop Park (1-2) | 7-4 | |
| » Starters: Chief Bender vs Al Orth | First | -- |
| Monday, May 1 |
| » Lost to Senators (8-6), 5-4 | Columbia Park (4-1) | 7-5 | |
| » Starters: Tom Hughes vs Andy Coakley | First | -- |
| Tuesday, May 2 |
| » Lost to Senators (9-6), 9-5 | Columbia Park (4-2) | 7-6 | Lost 2 |
| » Starters: Casey Patten vs Eddie Plank | Third | 1 out |
| Wednesday, May 3 |
| » Lost to Senators (10-6), 5-4 | Columbia Park (4-3) | 7-7 | Lost 3 |
| » Starters: Happy Townsend vs Chief Bender | Fourth | 2 out |
| Thursday, May 4 |
| » Defeated Senators (10-7), 6-0 | Columbia Park (5-3) | 8-7 | |
| » Starters: Beany Jacobson vs Rube Waddell | Third | 1 out |
| Friday, May 5 |
| » Lost to Senators (11-7), 4-2 | American League Park II (0-1) | 8-8 | |
| » Starters: Weldon Henley vs Barney Wolfe | Third | 2 out |
| Saturday, May 6 |
| » Defeated Senators (11-8), 2-1 | American League Park II (1-1) | 9-8 | |
| » Starters: Eddie Plank vs Tom Hughes | Third | 1 out |
| Monday, May 8 |
| » Defeated Senators (11-9), 3-2 | American League Park II (2-1) | 10-8 | Won 2 |
| » Starters: Rube Waddell vs Casey Patten | Second | ½ out |
| Tuesday, May 9 |
| » Lost to Senators (12-9), 3-1 | American League Park II (2-2) | 10-9 | |
| » Starters: Chief Bender vs Happy Townsend | Third | 1 out |
| Friday, May 12 |
| » Lost to Browns (10-10), 4-1 | Sportsman's Park II (0-1) | 10-10 | Lost 2 |
| » Starters: Weldon Henley vs Harry Howell | Third | 1½ out |
| Sunday, May 14 |
| » Defeated Browns (10-11), 10-2 | Sportsman's Park II (1-1) | 11-10 | |
| » Starters: Eddie Plank vs Willie Sudhoff | Second | 1½ out |
| Monday, May 15 |
| » Defeated Browns (10-12), 4-0 | Sportsman's Park II (2-1) | 12-10 | Won 2 |
| » Starters: Chief Bender vs Fred Glade | Second | ½ out |
| Thursday, May 18 |
| » Defeated White Sox (12-11), 3-0 | South Side Park III (1-0) | 13-10 | Won 3 |
| » Starters: Rube Waddell vs Frank Smith | Second | 1 out |
| Friday, May 19 |
| » Lost to White Sox (13-11), 2-1 | South Side Park III (1-1) | 13-11 | |
| » Starters: Eddie Plank vs Nick Altrock | Second | 1 out |
| Saturday, May 20 |
| » Lost to Indians (14-9), 4-1 | League Park I (0-1) | 13-12 | Lost 2 |
| » Starters: Chief Bender vs Addie Joss | Third | 2 out |
| Monday, May 22 |
| » Defeated Indians (14-10), 6-1 | League Park I (1-1) | 14-12 | |
| » Starters: Rube Waddell vs Bill Bernhard | Third | 1 out |
| Tuesday, May 23 |
| » Defeated Indians (14-11), 7-4 | League Park I (2-1) | 15-12 | Won 2 |
| » Starters: Eddie Plank vs Red Donahue | Third | 1 out |
| Wednesday, May 24 |
| » Lost to Indians (15-11), 6-5 | League Park I (2-2) | 15-13 | |
| » Starters: Weldon Henley vs Bob Rhoads | Third | 2 out |
| Thursday, May 25 |
| » Defeated Tigers (15-14), 9-7 | Bennett Park (1-0) | 16-13 | |
| » Starters: Rube Waddell vs Bill Donovan | Third | 1½ out |
| Friday, May 26 |
| » Defeated Tigers (15-15), 5-2 | Bennett Park (2-0) | 17-13 | Won 2 |
| » Starters: Chief Bender vs Ed Killian | Third | 1½ out |
| Saturday, May 27 |
| » Lost to Tigers (16-15), 3-2 | Bennett Park (2-1) | 17-14 | |
| » Starters: Eddie Plank vs George Mullin | Third | 2½ out |
| Monday, May 29 |
| » Defeated Yankees (13-21), 2-1 | Columbia Park (6-3) | 18-14 | |
| » Starters: Al Orth vs Rube Waddell | Third | 2 out |
| Tuesday, May 30 |
| » Defeated Yankees (13-22), 6-5 | Columbia Park (7-3) | 19-14 | Won 2 |
| » Starters: Jack Powell vs Andy Coakley | Third | 2½ out |
| Wednesday, May 31 |
| » Lost to Yankees (14-22), 8-3 | Columbia Park (7-4) | 19-15 | |
| » Starters: Bill Hogg vs Chief Bender | Third | 3½ out |
| Thursday, June 1 |
| » Defeated Senators (16-21), 6-5 | Columbia Park (8-4) | 20-15 | |
| » Starters: Tom Hughes vs Eddie Plank | Third | 2½ out |
| Friday, June 2 |
| » Defeated Senators (16-22), 3-1 | Columbia Park (9-4) | 21-15 | Won 2 |
| » Starters: Barney Wolfe vs Rube Waddell | Third | 2 out |
| Saturday, June 3 |
| » Defeated Senators (16-23), 8-1 | Columbia Park (10-4) | 22-15 | Won 3 |
| » Starters: Happy Townsend vs Andy Coakley | Second | 2 out |
| Monday, June 5 |
| » Lost to Senators (17-23), 6-4 | Columbia Park (10-5) | 22-16 | |
| » Starters: Casey Patten vs Weldon Henley | Second | 3 out |
| Tuesday, June 6 |
| » Defeated White Sox (22-17), 4-1 | Columbia Park (11-5) | 23-16 | |
| » Starters: Frank Smith vs Rube Waddell | Second | 2½ out |
| Wednesday, June 7 |
| » Lost to White Sox (23-17), 8-0 | Columbia Park (11-6) | 23-17 | |
| » Starters: Nick Altrock vs Chief Bender | Second | 3 out |
| Thursday, June 8 |
| » Defeated White Sox (23-18), 6-3 | Columbia Park (12-6) | 24-17 | |
| » Starters: Roy Patterson vs Eddie Plank | Second | 3 out |
| Friday, June 9 |
| » Lost to White Sox (24-18), 3-2 | Columbia Park (12-7) | 24-18 | |
| » Starters: Doc White vs Rube Waddell | Second | 4 out |
| Saturday, June 10 |
| » Defeated Tigers (22-21), 15-8 | Columbia Park (13-7) | 25-18 | |
| » Starters: George Mullin vs Andy Coakley | Second | 3 out |
| Tuesday, June 13 |
| » Lost to Tigers (23-21), 1-0 | Columbia Park (13-8) | 25-19 | |
| » Starters: Bill Donovan vs Rube Waddell | Third | 4 out |
| Wednesday, June 14 |
| » Defeated Tigers (23-22), 4-1 | Columbia Park (14-8) | 26-19 | |
| » Starters: Ed Killian vs Eddie Plank | Third | 3 out |
| Thursday, June 15 |
| » Lost to Browns (18-29), 5-0 | Columbia Park (14-9) | 26-20 | |
| » Starters: Harry Howell vs Chief Bender | Third | 4 out |
| Friday, June 16 |
| » Defeated Browns (18-30), 10-1 | Columbia Park (15-9) | 27-20 | |
| » Starters: Fred Glade vs Rube Waddell | Third | 4 out |
| » Major-league debuts: Branch Rickey (Browns) |
| Saturday, June 17 |
| » Defeated Browns (18-31), 3-1 | Columbia Park (16-9) | 28-20 | Won 2 |
| » Starters: Fred Glade vs Eddie Plank | Third | 4 out |
| Monday, June 19 |
| » Defeated Browns (18-32), 5-4 | Columbia Park (17-9) | 29-20 | Won 3 |
| » Starters: Harry Howell vs Weldon Henley | Third | 4 out |
| Tuesday, June 20 |
| » Lost to Indians (32-14), 3-2 | Columbia Park (17-10) | 29-21 | |
| » Starters: Addie Joss vs Rube Waddell | Third | 5 out |
| Wednesday, June 21 |
| » Defeated Indians (32-15), 7-3 | Columbia Park (18-10) | 30-21 | |
| » Starters: Earl Moore vs Eddie Plank | Third | 4 out |
| Thursday, June 22 |
| » Defeated Indians (32-16), 2-0 | Columbia Park (19-10) | 31-21 | Won 2 |
| » Starters: Otto Hess vs Andy Coakley | Third | 3 out |
| Friday, June 23 |
| » Defeated Indians (32-17), 3-0 | Columbia Park (20-10) | 32-21 | Won 3 |
| » Starters: Bob Rhoads vs Rube Waddell | Third | 2 out |
| Tuesday, June 27 |
| » Defeated Senators (21-34), 1-0 | American League Park II (3-2) | 33-21 | Won 4 |
| » Starters: Eddie Plank vs Casey Patten | Third | 1½ out |
| Wednesday, June 28 |
| » Lost to Senators (22-34), 6-3 | American League Park II (3-3) | 33-22 | |
| » Starters: Rube Waddell vs Happy Townsend | Third | 2 out |
| Thursday, June 29 |
| » Lost to Yankees (23-30), 13-4 | Hilltop Park (1-3) | 33-23 | Lost 2 |
| » Starters: Chief Bender vs Al Orth | Second | 2 out |
| Friday, June 30 |
| » Defeated Yankees (23-31), 7-4 | Hilltop Park (2-3) | 34-23 | |
| » Starters: Eddie Plank vs Bill Hogg | Third | 2 out |
| Saturday, July 1 |
| » Defeated Yankees (23-32), 1-0 | Hilltop Park (3-3) | 35-23 | Won 2 |
| » Starters: Andy Coakley vs Jack Chesbro | Second | 1½ out |
| » Defeated Yankees (23-33), 3-2 | Hilltop Park (4-3) | 36-23 | Won 3 |
| » Starters: Rube Waddell vs Bill Hogg | Second | 1½ out |
| Monday, July 3 |
| » Lost to Yankees (24-33), 3-0 | Hilltop Park (4-4) | 36-24 | |
| » Starters: Weldon Henley vs Al Orth | Second | 2½ out |
| Tuesday, July 4 |
| » Defeated Red Sox (27-29), 5-2 | Huntington Ave Baseball Grounds (3-2) | 37-24 | |
| » Starters: Eddie Plank vs Jesse Tannehill | Second | 1½ out |
| » Defeated Red Sox (27-30), 4-2 | Huntington Ave Baseball Grounds (4-2) | 38-24 | Won 2 |
| » Starters: Rube Waddell vs Cy Young | Second | 1½ out |
| Wednesday, July 5 |
| » Lost to Red Sox (28-30), 4-3 | Huntington Ave Baseball Grounds (4-3) | 38-25 | |
| » Starters: Weldon Henley vs Bill Dinneen | Third | 2½ out |
| Thursday, July 6 |
| » Defeated Red Sox (28-31), 7-4 | Columbia Park (21-10) | 39-25 | |
| » Starters: George Winter vs Andy Coakley | Second | 1½ out |
| Friday, July 7 |
| » Defeated Red Sox (28-32), 2-1 | Columbia Park (22-10) | 40-25 | Won 2 |
| » Starters: Cy Young vs Rube Waddell | Third | 1½ out |
| Saturday, July 8 |
| » Lost to Red Sox (29-32), 11-8 | Columbia Park (22-11) | 40-26 | |
| » Starters: Bill Dinneen vs Eddie Plank | Third | 1½ out |
| » Defeated Red Sox (29-33), 11-4 | Columbia Park (23-11) | 41-26 | |
| » Starters: George Winter vs Weldon Henley | Third | 1½ out |
| Monday, July 10 |
| » Defeated Indians (42-26), 6-3 | League Park I (3-2) | 42-26 | Won 2 |
| » Starters: Andy Coakley vs Addie Joss | Second | 1½ out |
| Tuesday, July 11 |
| » Lost to Indians (43-26), 7-0 | League Park I (3-3) | 42-27 | |
| » Starters: Eddie Plank vs Earl Moore | Third | 2 out |
| Thursday, July 13 |
| » Lost to Indians (44-26), 9-3 | League Park I (3-4) | 42-28 | Lost 2 |
| » Starters: Rube Waddell vs Red Donahue | Third | 2 out |
| Saturday, July 15 |
| » Lost to Tigers (36-36), 5-2 | Bennett Park (2-2) | 42-29 | Lost 3 |
| » Starters: Eddie Plank vs Ed Killian | Third | 2 out |
| » Defeated Tigers (36-37), 9-1 | Bennett Park (3-2) | 43-29 | |
| » Starters: Andy Coakley vs Bill Donovan | Third | 2 out |
| Monday, July 17 |
| » Lost to Tigers (37-37), 4-3 | Bennett Park (3-3) | 43-30 | |
| » Starters: Rube Waddell vs George Mullin | Third | 3 out |
| Tuesday, July 18 |
| » Defeated Tigers (37-38), 6-3 | Bennett Park (4-3) | 44-30 | |
| » Starters: Eddie Plank vs Bill Donovan | Third | 2 out |
| Wednesday, July 19 |
| » Defeated Browns (29-48), 7-3 | Sportsman's Park II (3-1) | 45-30 | Won 2 |
| » Starters: Rube Waddell vs Jim Buchanan | Second | 2½ out |
| Friday, July 21 |
| » Lost to Browns (30-48), 3-2 | Sportsman's Park II (3-2) | 45-31 | |
| » Starters: Andy Coakley vs Fred Glade | Third | 3½ out |
| Saturday, July 22 |
| » Defeated Browns (30-49), 6-0 | Sportsman's Park II (4-2) | 46-31 | |
| » Starters: Weldon Henley vs Barney Pelty | Third | 4 out |
| » Lost to Browns (31-49), 3-2 | Sportsman's Park II (4-3) | 46-32 | |
| » Starters: Rube Waddell vs Harry Howell | Third | 4 out |
| Future Athletic Doc Cramer is born in Beach Haven, NJ. |
| Sunday, July 23 |
| » Defeated White Sox (47-31), 1-0 | South Side Park III (2-1) | 47-32 | |
| » Starters: Eddie Plank vs Frank Owen | Third | 3½ out |
| Monday, July 24 |
| » Lost to White Sox (48-31), 2-1 | South Side Park III (2-2) | 47-33 | |
| » Starters: Chief Bender vs Nick Altrock | Third | 4½ out |
| Tuesday, July 25 |
| » Defeated White Sox (48-32), 8-2 | South Side Park III (3-2) | 48-33 | |
| » Starters: Rube Waddell vs Doc White | Third | 3½ out |
| Wednesday, July 26 |
| » Lost to White Sox (49-32), 5-2 | South Side Park III (3-3) | 48-34 | |
| » Starters: Andy Coakley vs Frank Owen | Third | 4 out |
| Thursday, July 27 |
| » Tied White Sox, 4-4 | South Side Park III (3-3) | 48-34 | |
| » Starters: Eddie Plank vs Nick Altrock | Third | 3½ out |
| Saturday, July 29 |
| » Lost to White Sox (50-32), 5-2 | Columbia Park (23-12) | 48-35 | Lost 2 |
| » Starters: Frank Owen vs Rube Waddell | Third | 2½ out |
| Monday, July 31 |
| » Defeated White Sox (50-33), 4-1 | Columbia Park (24-12) | 49-35 | |
| » Starters: Doc White vs Eddie Plank | Third | 2 out |
| Tuesday, August 1 |
| » Defeated White Sox (50-34), 5-4 | Columbia Park (25-12) | 50-35 | Won 2 |
| » Starters: Nick Altrock vs Weldon Henley | Third | 2 out |
| Wednesday, August 2 |
| » Defeated White Sox (50-35), 4-3 | Columbia Park (26-12) | 51-35 | Won 3 |
| » Starters: Frank Owen vs Rube Waddell | First | -- |
| Thursday, August 3 |
| » Defeated Tigers (43-46), 3-2 | Columbia Park (27-12) | 52-35 | Won 4 |
| » Starters: George Mullin vs Andy Coakley | First | -- |
| Friday, August 4 |
| » Defeated Tigers (43-47), 8-0 | Columbia Park (28-12) | 53-35 | Won 5 |
| » Starters: Bill Donovan vs Eddie Plank | First | -- |
| » Lost to Tigers (44-47), 3-2 | Columbia Park (28-13) | 53-36 | |
| » Starters: Frank Kitson vs Weldon Henley | First | -- |
| Saturday, August 5 |
| » Defeated Tigers (44-48), 5-3 | Columbia Park (29-13) | 54-36 | |
| » Starters: Ed Killian vs Rube Waddell | First | -- |
| Monday, August 7 |
| » Lost to Tigers (45-48), 9-3 | Columbia Park (29-14) | 54-37 | |
| » Starters: George Mullin vs Chief Bender | First | -- |
| Tuesday, August 8 |
| » Lost to Indians (54-41), 5-4 | Columbia Park (29-15) | 54-38 | Lost 2 |
| » Starters: Bob Rhoads vs Eddie Plank | First | -- |
| Friday, August 11 |
| » Defeated Indians (54-42), 7-6 | Columbia Park (30-15) | 55-38 | |
| » Starters: Addie Joss vs Rube Waddell | First | -- |
| Saturday, August 12 |
| » Defeated Browns (34-62), 6-4 | Columbia Park (31-15) | 56-38 | Won 2 |
| » Starters: Fred Glade vs Eddie Plank | First | -- |
| Monday, August 14 |
| » Defeated Browns (34-63), 2-1 | Columbia Park (32-15) | 57-38 | Won 3 |
| » Starters: Barney Pelty vs Chief Bender | First | -- |
| Tuesday, August 15 |
| » Defeated Browns (34-64), 2-0 | Columbia Park (33-15) | 58-38 | Won 4 |
| » Starters: Harry Howell vs Rube Waddell | First | -- |
| Wednesday, August 16 |
| » Defeated Browns (34-65), 6-4 | Columbia Park (34-15) | 59-38 | Won 5 |
| » Starters: Willie Sudhoff vs Andy Coakley | First | -- |
| Thursday, August 17 |
| » Defeated Tigers (48-54), 6-2 | Bennett Park (5-3) | 60-38 | Won 6 |
| » Starters: Eddie Plank vs George Mullin | First | -- |
| Friday, August 18 |
| » Tied Browns, 3-3 | Sportsman's Park II (4-3) | 60-38 | |
| » Starters: Weldon Henley vs Fred Glade | First | -- |
| Saturday, August 19 |
| » Lost to Browns (35-65), 1-0 | Sportsman's Park II (4-4) | 60-39 | |
| » Starters: Andy Coakley vs Harry Howell | First | -- |
| Sunday, August 20 |
| » Lost to Browns (36-65), 3-2 | Sportsman's Park II (4-5) | 60-40 | Lost 2 |
| » Starters: Eddie Plank vs Barney Pelty | First | -- |
| » Lost to Browns (37-65), 6-4 | Sportsman's Park II (4-6) | 60-41 | Lost 3 |
| » Starters: Rube Waddell vs Willie Sudhoff | First | -- |
| Monday, August 21 |
| » Defeated Browns (37-66), 4-2 | Sportsman's Park II (5-6) | 61-41 | |
| » Starters: Andy Coakley vs Jim Buchanan | First | -- |
| Tuesday, August 22 |
| » Defeated White Sox (55-43), 4-0 | South Side Park III (4-3) | 62-41 | Won 2 |
| » Starters: Rube Waddell vs Roy Patterson | First | -- |
| » Lost to White Sox (56-43), 2-1 | South Side Park III (4-4) | 62-42 | |
| » Starters: Weldon Henley vs Nick Altrock | First | -- |
| Wednesday, August 23 |
| » Lost to White Sox (57-43), 3-1 | South Side Park III (4-5) | 62-43 | Lost 2 |
| » Starters: Eddie Plank vs Doc White | First | -- |
| » Defeated White Sox (57-44), 4-2 | South Side Park III (5-5) | 63-43 | |
| » Starters: Andy Coakley vs Frank Smith | First | -- |
| Friday, August 25 |
| » Defeated Tigers (50-59), 6-3 | Bennett Park (6-3) | 64-43 | Won 2 |
| » Starters: Andy Coakley vs George Mullin | First | -- |
| Saturday, August 26 |
| » Lost to Tigers (51-59), 5-4 | Bennett Park (6-4) | 64-44 | |
| » Starters: Weldon Henley vs Bill Donovan | First | -- |
| Monday, August 28 |
| » Defeated Tigers (51-60), 5-4 | Bennett Park (7-4) | 65-44 | |
| » Starters: Eddie Plank vs Frank Kitson | First | -- |
| Tuesday, August 29 |
| » Defeated Indians (61-50), 6-0 | League Park I (4-4) | 66-44 | Won 2 |
| » Starters: Rube Waddell vs Red Donahue | First | -- |
| » Defeated Indians (61-51), 4-2 | League Park I (5-4) | 67-44 | Won 3 |
| » Starters: Andy Coakley vs Bill Bernhard | First | -- |
| Wednesday, August 30 |
| » Defeated Indians (61-52), 6-2 | League Park I (6-4) | 68-44 | Won 4 |
| » Starters: Eddie Plank vs Earl Moore | First | -- |
| Thursday, August 31 |
| » Defeated Indians (61-53), 2-0 | League Park I (7-4) | 69-44 | Won 5 |
| » Starters: Rube Waddell vs Addie Joss | First | -- |
| Sunday, September 3 |
| » Major-league debuts: Eddie Cicotte (Tigers) |
| Monday, September 4 |
| » Defeated Senators (47-66), 5-0 | Columbia Park (35-15) | 70-44 | Won 6 |
| » Starters: Casey Patten vs Chief Bender | First | -- |
| » Defeated Senators (47-67), 5-4 | Columbia Park (36-15) | 71-44 | Won 7 |
| » Starters: Happy Townsend vs Andy Coakley | First | -- |
| Tuesday, September 5 |
| » Lost to Red Sox (58-56), 3-2 | Huntington Ave Baseball Grounds (4-4) | 71-45 | |
| » Starters: Rube Waddell vs George Winter | First | -- |
| Wednesday, September 6 |
| » Defeated Red Sox (58-57), 2-1 | Huntington Ave Baseball Grounds (5-4) | 72-45 | |
| » Starters: Eddie Plank vs Ed Barry | First | -- |
| Thursday, September 7 |
| » Defeated Red Sox (58-58), 3-2 | Huntington Ave Baseball Grounds (6-4) | 73-45 | Won 2 |
| » Starters: Andy Coakley vs Norwood Gibson | First | -- |
| Friday, September 8 |
| » Defeated Red Sox (58-59), 5-3 | Huntington Ave Baseball Grounds (7-4) | 74-45 | Won 3 |
| » Starters: Rube Waddell vs Cy Young | First | -- |
| Saturday, September 9 |
| » Defeated Yankees (59-58), 6-2 | Columbia Park (37-15) | 75-45 | Won 4 |
| » Starters: Clark Griffith vs Eddie Plank | First | -- |
| » Tied Yankees, 7-7 | Columbia Park (37-15) | 75-45 | |
| » Starters: Bill Hogg vs Chief Bender | First | -- |
| Future Athletic Charlie Perkins is born in Ensley, AL. |
| Tuesday, September 12 |
| » Defeated Yankees (59-59), 4-3 | Columbia Park (38-15) | 76-45 | Won 5 |
| » Starters: Jack Chesbro vs Andy Coakley | First | -- |
| » Lost to Yankees (60-59), 7-4 | Columbia Park (38-16) | 76-46 | |
| » Starters: Al Orth vs Jimmy Dygert | First | -- |
| Wednesday, September 13 |
| » Defeated Red Sox (60-61), 1-0 | Columbia Park (39-16) | 77-46 | |
| » Starters: Jesse Tannehill vs Eddie Plank | First | -- |
| Thursday, September 14 |
| » Lost to Red Sox (61-61), 4-3 | Columbia Park (39-17) | 77-47 | |
| » Starters: Norwood Gibson vs Chief Bender | First | -- |
| Friday, September 15 |
| » Defeated Red Sox (61-62), 4-3 | Columbia Park (40-17) | 78-47 | |
| » Starters: George Winter vs Andy Coakley | First | -- |
| » Lost to Red Sox (62-62), 3-2 | Columbia Park (40-18) | 78-48 | |
| » Starters: Ed Hughes vs Jimmy Dygert | First | -- |
| Saturday, September 16 |
| » Defeated Red Sox (62-63), 6-2 | Columbia Park (41-18) | 79-48 | |
| » Starters: Jesse Tannehill vs Eddie Plank | First | -- |
| Tuesday, September 19 |
| » Lost to Yankees (64-61), 5-0 | Hilltop Park (4-5) | 79-49 | |
| » Starters: Andy Coakley vs Ambrose Puttmann | First | -- |
| » Defeated Yankees (64-62), 3-0 | Hilltop Park (5-5) | 80-49 | |
| » Starters: Chief Bender vs Wilbur Good | First | -- |
| Wednesday, September 20 |
| » Lost to Yankees (65-62), 1-0 | Hilltop Park (5-6) | 80-50 | |
| » Starters: Weldon Henley vs Bill Hogg | First | -- |
| Thursday, September 21 |
| » Defeated Indians (69-66), 2-1 | Columbia Park (42-18) | 81-50 | |
| » Starters: Addie Joss vs Eddie Plank | First | -- |
| Friday, September 22 |
| » Lost to Indians (70-66), 8-4 | Columbia Park (42-19) | 81-51 | |
| » Starters: Bob Rhoads vs Jimmy Dygert | First | -- |
| » Defeated Indians (70-67), 2-1 | Columbia Park (43-19) | 82-51 | |
| » Starters: Earl Moore vs Andy Coakley | First | -- |
| Saturday, September 23 |
| » Defeated Indians (70-68), 5-2 | Columbia Park (44-19) | 83-51 | Won 2 |
| » Starters: Red Donahue vs Weldon Henley | First | -- |
| » Defeated Indians (70-69), 3-2 | Columbia Park (45-19) | 84-51 | Won 3 |
| » Starters: Bill Bernhard vs Eddie Plank | First | -- |
| Monday, September 25 |
| » Defeated Tigers (70-70), 3-2 | Columbia Park (46-19) | 85-51 | Won 4 |
| » Starters: Jimmy Wiggs vs Chief Bender | First | -- |
| Tuesday, September 26 |
| » Lost to Tigers (71-70), 6-4 | Columbia Park (46-20) | 85-52 | |
| » Starters: George Mullin vs Andy Coakley | First | -- |
| Wednesday, September 27 |
| » Lost to Tigers (72-70), 8-7 | Columbia Park (46-21) | 85-53 | Lost 2 |
| » Starters: John Eubank vs Weldon Henley | First | -- |
| Thursday, September 28 |
| » Defeated White Sox (87-56), 3-2 | Columbia Park (47-21) | 86-53 | |
| » Starters: Roy Patterson vs Eddie Plank | First | -- |
| Friday, September 29 |
| » Defeated White Sox (87-57), 11-1 | Columbia Park (48-21) | 87-53 | Won 2 |
| » Starters: Nick Altrock vs Chief Bender | First | -- |
| Saturday, September 30 |
| » Lost to White Sox (88-57), 4-3 | Columbia Park (48-22) | 87-54 | |
| » Starters: Frank Owen vs Eddie Plank | First | -- |
| Monday, October 2 |
| » Defeated Browns (52-95), 5-0 | Columbia Park (49-22) | 88-54 | |
| » Starters: Jim Buchanan vs Andy Coakley | First | -- |
| Tuesday, October 3 |
| » Defeated Browns (52-96), 5-2 | Columbia Park (50-22) | 89-54 | Won 2 |
| » Starters: Willie Sudhoff vs Weldon Henley | First | -- |
| Wednesday, October 4 |
| » Defeated Browns (52-97), 4-1 | Columbia Park (51-22) | 90-54 | Won 3 |
| » Starters: Harry Howell vs Eddie Plank | First | -- |
| Thursday, October 5 |
| » Defeated Senators (62-86), 8-0 | American League Park II (4-3) | 91-54 | Won 4 |
| » Starters: Chief Bender vs Happy Townsend | First | -- |
| » Defeated Senators (62-87), 9-7 | American League Park II (5-3) | 92-54 | Won 5 |
| » Starters: Andy Coakley vs Casey Patten | First | -- |
| Friday, October 6 |
| » Lost to Senators (63-87), 10-4 | American League Park II (5-4) | 92-55 | |
| » Starters: Andy Coakley vs Cy Falkenberg | First | -- |
| Saturday, October 7 |
| » Lost to Senators (64-87), 5-4 | American League Park II (5-5) | 92-56 | Lost 2 |
| » Starters: Rube Waddell vs Harry Hardy | First | -- |
| » Tied Senators, 3-3 | American League Park II (5-5) | 92-56 | |
| » Starters: Joseph Myers vs Moxie Manuel | First | -- |
| Saturday, November 4 |
| Future Athletic Lefty Willis is born in Leetown, WV. |
Game information provided by Retrosheet (www.retrosheet.org) |
