| Sunday, January 3 |
| Future Indian Bill Cissell is born in Perryville, MO. |
| Thursday, April 14 |
| » Defeated White Sox (0-1), 6-1 | South Side Park III (1-0) | 1-0 | |
| » Starters: Bill Bernhard vs Frank Owen | First | -- |
| » Major-league debuts: Gus Dundon (White Sox) |
| Friday, April 15 |
| » Major-league debuts: Doc Marshall (Phillies) |
| Saturday, April 16 |
| » Lost to White Sox (1-1), 10-8 | South Side Park III (1-1) | 1-1 | |
| » Starters: Jack Hickey vs Nick Altrock | Third | 1 out |
| Sunday, April 17 |
| » Defeated White Sox (1-2), 5-0 | South Side Park III (2-1) | 2-1 | |
| » Starters: Red Donahue vs Doc White | Second | ½ out |
| Monday, April 18 |
| » Defeated Browns (1-3), 10-4 | Sportsman's Park II (1-0) | 3-1 | Won 2 |
| » Starters: Bill Bernhard vs Gene Wright | Second | ½ out |
| Tuesday, April 19 |
| » Lost to Browns (2-3), 4-2 | Sportsman's Park II (1-1) | 3-2 | |
| » Starters: Bob Rhoads vs Ed Siever | Third | 1½ out |
| Friday, April 22 |
| » Defeated White Sox (3-4), 10-2 | League Park I (1-0) | 4-2 | |
| » Starters: Elmer Stricklett vs Bill Bernhard | Second | 1½ out |
| » Major-league debuts: Claude Berry and Elmer Stricklett (White Sox) |
| Saturday, April 23 |
| » Lost to White Sox (4-4), 6-5 | League Park I (1-1) | 4-3 | |
| » Starters: Doc White vs Red Donahue | Second | 2½ out |
| Sunday, April 24 |
| » Lost to White Sox (5-4), 5-4 | South Side Park III (2-2) | 4-4 | Lost 2 |
| » Starters: Otto Hess vs Patsy Flaherty | Fifth | 3 out |
| » Major-league debuts: Tom Dougherty (White Sox) |
| Monday, April 25 |
| » Lost to White Sox (6-4), 7-4 | League Park I (1-2) | 4-5 | Lost 3 |
| » Starters: Frank Owen vs Addie Joss | Sixth | 3 out |
| Saturday, April 30 |
| » Lost to Browns (5-4), 7-1 | League Park I (1-3) | 4-6 | Lost 4 |
| » Starters: Harry Howell vs Bill Bernhard | Seventh | 5 out |
| Monday, May 2 |
| » Lost to Tigers (7-6), 6-2 | Bennett Park (0-1) | 4-7 | Lost 5 |
| » Starters: Red Donahue vs Bill Donovan | Seventh | 5 out |
| Tuesday, May 3 |
| » Defeated Tigers (7-7), 10-2 | Bennett Park (1-1) | 5-7 | |
| » Starters: Bob Rhoads vs Frank Kitson | Sixth | 5 out |
| Wednesday, May 4 |
| » Lost to Tigers (8-7), 3-2 | Bennett Park (1-2) | 5-8 | |
| » Starters: Jack Hickey vs Ed Killian | Sixth | 6 out |
| Thursday, May 5 |
| » Defeated Tigers (8-8), 5-3 | Bennett Park (2-2) | 6-8 | |
| » Starters: Bill Bernhard vs George Mullin | Sixth | 6 out |
| Friday, May 6 |
| » Defeated Tigers (8-9), 3-1 | League Park I (2-3) | 7-8 | Won 2 |
| » Starters: Jesse Stovall vs Red Donahue | Fifth | 6 out |
| Saturday, May 7 |
| » Defeated Tigers (8-10), 5-2 | League Park I (3-3) | 8-8 | Won 3 |
| » Starters: Bill Donovan vs Addie Joss | Fourth | 5 out |
| Monday, May 9 |
| » Defeated Tigers (8-11), 7-2 | League Park I (4-3) | 9-8 | Won 4 |
| » Starters: George Mullin vs Earl Moore | Fifth | 4½ out |
| Wednesday, May 11 |
| » Lost to Yankees (11-7), 4-3 | Hilltop Park (0-1) | 9-9 | |
| » Starters: Bill Bernhard vs Tom Hughes | Fourth | 5 out |
| Thursday, May 12 |
| » Defeated Yankees (11-8), 7-0 | Hilltop Park (1-1) | 10-9 | |
| » Starters: Red Donahue vs Jack Chesbro | Fourth | 5 out |
| Friday, May 13 |
| » Lost to Yankees (12-8), 7-6 | Hilltop Park (1-2) | 10-10 | |
| » Starters: Earl Moore vs Jack Powell | Fourth | 6 out |
| Saturday, May 14 |
| » Lost to Yankees (13-8), 10-1 | Hilltop Park (1-3) | 10-11 | Lost 2 |
| » Starters: Bob Rhoads vs Jack Chesbro | Fourth | 7 out |
| Monday, May 16 |
| » Defeated Red Sox (18-6), 9-4 | Huntington Ave Baseball Grounds (1-0) | 11-11 | |
| » Starters: Bill Bernhard vs Norwood Gibson | Fourth | 6 out |
| Tuesday, May 17 |
| » Defeated Red Sox (18-7), 3-1 | Huntington Ave Baseball Grounds (2-0) | 12-11 | Won 2 |
| » Starters: Red Donahue vs Cy Young | Third | 5 out |
| Friday, May 20 |
| » Defeated Athletics (15-11), 8-5 | Columbia Park (1-0) | 13-11 | Won 3 |
| » Starters: Earl Moore vs Weldon Henley | Fourth | 5 out |
| Future Indian Pete Appleton is born in Terryville, CT. |
| Saturday, May 21 |
| » Lost to Athletics (16-11), 7-0 | Columbia Park (1-1) | 13-12 | |
| » Starters: Bill Bernhard vs Eddie Plank | Fifth | 5 out |
| Sunday, May 22 |
| Future Indian Ed Morgan is born in Cairo, IL. |
| Monday, May 23 |
| » Defeated Athletics (16-12), 4-3 | Columbia Park (2-1) | 14-12 | |
| » Starters: Red Donahue vs Rube Waddell | Fifth | 4 out |
| Tuesday, May 24 |
| » Defeated Senators (6-20), 10-6 | American League Park II (1-0) | 15-12 | Won 2 |
| » Starters: Bob Rhoads vs Davey Dunkle | Third | 4 out |
| Wednesday, May 25 |
| » Defeated Senators (6-21), 7-3 | American League Park II (2-0) | 16-12 | Won 3 |
| » Starters: Earl Moore vs Happy Townsend | Second | 4 out |
| Thursday, May 26 |
| » Defeated Senators (6-22), 7-3 | American League Park II (3-0) | 17-12 | Won 4 |
| » Starters: Bill Bernhard vs Beany Jacobson | Second | 3 out |
| Friday, May 27 |
| » Defeated Browns (14-17), 5-2 | League Park I (5-3) | 18-12 | Won 5 |
| » Starters: Fred Glade vs Red Donahue | Second | 3 out |
| Saturday, May 28 |
| » Defeated White Sox (18-17), 9-4 | League Park I (6-3) | 19-12 | Won 6 |
| » Starters: Doc White vs Earl Moore | Second | 3 out |
| Sunday, May 29 |
| » Lost to White Sox (19-17), 4-3 | South Side Park III (2-3) | 19-13 | |
| » Starters: Otto Hess vs Nick Altrock | Second | 3½ out |
| Wednesday, June 1 |
| » Lost to Red Sox (26-10), 4-2 | League Park I (6-4) | 19-14 | Lost 2 |
| » Starters: Cy Young vs Bill Bernhard | Second | 5½ out |
| Thursday, June 2 |
| » Defeated Red Sox (26-11), 6-5 | League Park I (7-4) | 20-14 | |
| » Starters: Bill Dinneen vs Otto Hess | Second | 4½ out |
| Friday, June 3 |
| » Defeated Red Sox (26-12), 2-1 | League Park I (8-4) | 21-14 | Won 2 |
| » Starters: Norwood Gibson vs Red Donahue | Second | 3½ out |
| Saturday, June 4 |
| » Lost to Red Sox (27-12), 3-2 | League Park I (8-5) | 21-15 | |
| » Starters: Jesse Tannehill vs Earl Moore | Second | 4½ out |
| Monday, June 6 |
| » Defeated Yankees (22-17), 5-1 | League Park I (9-5) | 22-15 | |
| » Starters: Tom Hughes vs Bill Bernhard | Second | 4½ out |
| Wednesday, June 8 |
| » Lost to Yankees (23-17), 4-1 | League Park I (9-6) | 22-16 | |
| » Starters: Jack Powell vs Red Donahue | Second | 5 out |
| Thursday, June 9 |
| » Lost to Yankees (24-17), 3-2 | League Park I (9-7) | 22-17 | Lost 2 |
| » Starters: Jack Chesbro vs Earl Moore | Fourth | 5 out |
| Friday, June 10 |
| » Defeated Athletics (22-20), 3-1 | League Park I (10-7) | 23-17 | |
| » Starters: Weldon Henley vs Bill Bernhard | Third | 5 out |
| Saturday, June 11 |
| » Lost to Athletics (23-20), 1-0 | League Park I (10-8) | 23-18 | |
| » Starters: Eddie Plank vs Bob Rhoads | Fourth | 5 out |
| Monday, June 13 |
| » Lost to Athletics (24-20), 9-2 | League Park I (10-9) | 23-19 | Lost 2 |
| » Starters: Rube Waddell vs Earl Moore | Fourth | 6½ out |
| Tuesday, June 14 |
| » Lost to Athletics (25-20), 4-0 | League Park I (10-10) | 23-20 | Lost 3 |
| » Starters: Chief Bender vs Bill Bernhard | Fifth | 7 out |
| Wednesday, June 15 |
| » Defeated Senators (8-36), 8-0 | League Park I (11-10) | 24-20 | |
| » Starters: Davey Dunkle vs Red Donahue | Fourth | 6 out |
| Thursday, June 16 |
| » Lost to Senators (9-36), 5-3 | League Park I (11-11) | 24-21 | |
| » Starters: Al Orth vs Bob Rhoads | Fourth | 6 out |
| Friday, June 17 |
| » Defeated Senators (9-37), 10-2 | League Park I (12-11) | 25-21 | |
| » Starters: Casey Patten vs Earl Moore | Fourth | 5½ out |
| Saturday, June 18 |
| » Defeated Senators (9-38), 8-4 | League Park I (13-11) | 26-21 | Won 2 |
| » Starters: Happy Townsend vs Addie Joss | Fourth | 5½ out |
| Tuesday, June 21 |
| » Lost to White Sox (30-23), 2-1 | South Side Park III (2-4) | 26-22 | |
| » Starters: Red Donahue vs Frank Owen | Fourth | 6½ out |
| Wednesday, June 22 |
| » Lost to White Sox (31-23), 6-5 | South Side Park III (2-5) | 26-23 | Lost 2 |
| » Starters: Earl Moore vs Doc White | Fourth | 7½ out |
| Thursday, June 23 |
| » Lost to White Sox (32-23), 2-1 | South Side Park III (2-6) | 26-24 | Lost 3 |
| » Starters: Bill Bernhard vs Frank Smith | Fifth | 7½ out |
| Saturday, June 25 |
| » Lost to Browns (25-26), 5-2 | Sportsman's Park II (1-2) | 26-25 | Lost 4 |
| » Starters: Red Donahue vs Harry Howell | Fifth | 7 out |
| Sunday, June 26 |
| » Defeated Browns (25-27), 7-4 | Sportsman's Park II (2-2) | 27-25 | |
| » Starters: Earl Moore vs Ed Siever | Fifth | 6½ out |
| Tuesday, June 28 |
| » Defeated Browns (25-28), 4-0 | Sportsman's Park II (3-2) | 28-25 | Won 2 |
| » Starters: Addie Joss vs Barney Pelty | Fifth | 6 out |
| Saturday, July 2 |
| » Defeated Tigers (23-35), 3-2 | Bennett Park (3-2) | 29-25 | Won 3 |
| » Starters: Bill Bernhard vs Jesse Stovall | Fifth | 6½ out |
| » Lost to Tigers (24-35), 5-2 | Bennett Park (3-3) | 29-26 | |
| » Starters: Red Donahue vs Frank Kitson | Fifth | 6½ out |
| Sunday, July 3 |
| » Defeated Browns (26-31), 3-1 | Sportsman's Park II (4-2) | 30-26 | |
| » Starters: Bob Rhoads vs Harry Howell | Fifth | 6 out |
| Monday, July 4 |
| » Lost to Browns (27-31), 12-10 | League Park I (13-12) | 30-27 | |
| » Starters: Barney Pelty vs Addie Joss | Fourth | 7 out |
| » Defeated Browns (27-32), 9-4 | League Park I (14-12) | 31-27 | |
| » Starters: Fred Glade vs Earl Moore | Fourth | 7 out |
| » Major-league debuts: George Stovall (Indians) |
| Tuesday, July 5 |
| » Defeated Browns (27-33), 14-4 | League Park I (15-12) | 32-27 | Won 2 |
| » Starters: Ed Siever vs Bill Bernhard | Fourth | 7 out |
| Thursday, July 7 |
| » Defeated Tigers (27-36), 4-2 | League Park I (16-12) | 33-27 | Won 3 |
| » Starters: George Mullin vs Addie Joss | Fourth | 7½ out |
| Friday, July 8 |
| » Defeated Tigers (27-37), 3-1 | League Park I (17-12) | 34-27 | Won 4 |
| » Starters: Ed Killian vs Bob Rhoads | Fourth | 7 out |
| » Defeated Tigers (27-38), 2-1 | League Park I (18-12) | 35-27 | Won 5 |
| » Starters: Frank Kitson vs Otto Hess | Fourth | 7 out |
| Saturday, July 9 |
| » Lost to Tigers (28-38), 5-3 | League Park I (18-13) | 35-28 | |
| » Starters: Bill Donovan vs Earl Moore | Fourth | 8 out |
| Monday, July 11 |
| » Lost to White Sox (43-29), 11-1 | League Park I (18-14) | 35-29 | Lost 2 |
| » Starters: Frank Smith vs Bill Bernhard | Fourth | 8 out |
| Tuesday, July 12 |
| » Defeated Yankees (41-27), 3-1 | Hilltop Park (2-3) | 36-29 | |
| » Starters: Addie Joss vs Tom Hughes | Fourth | 8 out |
| Wednesday, July 13 |
| » Defeated Yankees (41-28), 16-3 | Hilltop Park (3-3) | 37-29 | Won 2 |
| » Starters: Bill Bernhard vs Clark Griffith | Fourth | 8 out |
| Thursday, July 14 |
| » Lost to Yankees (42-28), 21-3 | Hilltop Park (3-4) | 37-30 | |
| » Starters: Bob Rhoads vs Jack Chesbro | Fourth | 8 out |
| Friday, July 15 |
| » Lost to Yankees (43-28), 3-2 | Hilltop Park (3-5) | 37-31 | Lost 2 |
| » Starters: Earl Moore vs Jack Powell | Fifth | 9 out |
| Saturday, July 16 |
| » Lost to Red Sox (49-24), 13-3 | Huntington Ave Baseball Grounds (2-1) | 37-32 | Lost 3 |
| » Starters: Addie Joss vs Cy Young | Fifth | 10 out |
| Monday, July 18 |
| » Lost to Red Sox (50-24), 4-3 | Huntington Ave Baseball Grounds (2-2) | 37-33 | Lost 4 |
| » Starters: Red Donahue vs Jesse Tannehill | Fifth | 11 out |
| Tuesday, July 19 |
| » Defeated Red Sox (50-25), 3-1 | Huntington Ave Baseball Grounds (3-2) | 38-33 | |
| » Starters: Bill Bernhard vs Bill Dinneen | Fifth | 10 out |
| Wednesday, July 20 |
| » Defeated Red Sox (50-26), 5-1 | Huntington Ave Baseball Grounds (4-2) | 39-33 | Won 2 |
| » Starters: Earl Moore vs Norwood Gibson | Fifth | 8 out |
| » Defeated Red Sox (50-27), 9-0 | Huntington Ave Baseball Grounds (5-2) | 40-33 | Won 3 |
| » Starters: Addie Joss vs Cy Young | Fifth | 8 out |
| Thursday, July 21 |
| » Defeated Athletics (42-34), 14-8 | Columbia Park (3-1) | 41-33 | Won 4 |
| » Starters: Red Donahue vs Weldon Henley | Fourth | 7 out |
| Friday, July 22 |
| » Defeated Athletics (42-35), 4-0 | Columbia Park (4-1) | 42-33 | Won 5 |
| » Starters: Bill Bernhard vs Chief Bender | Fourth | 6 out |
| Saturday, July 23 |
| » Defeated Athletics (42-36), 3-2 | Columbia Park (5-1) | 43-33 | Won 6 |
| » Starters: Earl Moore vs Rube Waddell | Fourth | 4½ out |
| » Defeated Athletics (42-37), 4-1 | Columbia Park (6-1) | 44-33 | Won 7 |
| » Starters: Addie Joss vs Eddie Plank | Fourth | 4½ out |
| Wednesday, July 27 |
| » Lost to Senators (17-61), 3-2 | American League Park II (3-1) | 44-34 | |
| » Starters: Red Donahue vs Casey Patten | Fourth | 5 out |
| » Defeated Senators (17-62), 7-0 | American League Park II (4-1) | 45-34 | |
| » Starters: Bill Bernhard vs Happy Townsend | Fourth | 5 out |
| Friday, July 29 |
| » Lost to Senators (18-62), 1-0 | American League Park II (4-2) | 45-35 | |
| » Starters: Earl Moore vs Beany Jacobson | Fourth | 4½ out |
| » Defeated Senators (18-63), 6-2 | American League Park II (5-2) | 46-35 | |
| » Starters: Addie Joss vs Barney Wolfe | Fourth | 4½ out |
| Saturday, July 30 |
| » Defeated Senators (18-64), 9-4 | League Park I (19-14) | 47-35 | Won 2 |
| » Starters: Casey Patten vs Red Donahue | Fourth | 3½ out |
| Monday, August 1 |
| » Lost to Red Sox (53-33), 8-0 | League Park I (19-15) | 47-36 | |
| » Starters: Cy Young vs Bill Bernhard | Fourth | 4½ out |
| Tuesday, August 2 |
| » Lost to Red Sox (54-33), 4-1 | League Park I (19-16) | 47-37 | Lost 2 |
| » Starters: Jesse Tannehill vs Addie Joss | Fourth | 5½ out |
| Wednesday, August 3 |
| » Lost to Red Sox (55-33), 7-2 | League Park I (19-17) | 47-38 | Lost 3 |
| » Starters: Bill Dinneen vs Earl Moore | Fifth | 6½ out |
| Thursday, August 4 |
| » Defeated Red Sox (55-34), 11-1 | League Park I (20-17) | 48-38 | |
| » Starters: Norwood Gibson vs Red Donahue | Fifth | 6 out |
| Friday, August 5 |
| » Lost to Yankees (54-34), 5-0 | League Park I (20-18) | 48-39 | |
| » Starters: Jack Powell vs Bill Bernhard | Fifth | 5½ out |
| Saturday, August 6 |
| » Lost to Yankees (55-34), 4-3 | League Park I (20-19) | 48-40 | Lost 2 |
| » Starters: Jack Chesbro vs Addie Joss | Fifth | 6½ out |
| Monday, August 8 |
| » Defeated Yankees (55-35), 9-1 | League Park I (21-19) | 49-40 | |
| » Starters: Al Orth vs Red Donahue | Fifth | 5½ out |
| Tuesday, August 9 |
| » Defeated Yankees (55-36), 6-3 | League Park I (22-19) | 50-40 | Won 2 |
| » Starters: Jack Powell vs Earl Moore | Fifth | 5 out |
| Thursday, August 11 |
| » Lost to Athletics (53-39), 2-1 | League Park I (22-20) | 50-41 | |
| » Starters: Rube Waddell vs Bill Bernhard | Fifth | 6½ out |
| Friday, August 12 |
| » Lost to Athletics (54-39), 5-0 | League Park I (22-21) | 50-42 | Lost 2 |
| » Starters: Weldon Henley vs Addie Joss | Fifth | 6½ out |
| Saturday, August 13 |
| » Defeated Athletics (54-40), 7-2 | League Park I (23-21) | 51-42 | |
| » Starters: Eddie Plank vs Red Donahue | Fifth | 6 out |
| Monday, August 15 |
| » Defeated Senators (22-74), 1-0 | League Park I (24-21) | 52-42 | Won 2 |
| » Starters: Happy Townsend vs Earl Moore | Fifth | 5½ out |
| Tuesday, August 16 |
| » Defeated Senators (22-75), 7-1 | League Park I (25-21) | 53-42 | Won 3 |
| » Starters: Beany Jacobson vs Bill Bernhard | Fifth | 5½ out |
| Wednesday, August 17 |
| » Defeated Senators (22-76), 3-2 | League Park I (26-21) | 54-42 | Won 4 |
| » Starters: Tom Hughes vs Bob Rhoads | Fifth | 4½ out |
| Thursday, August 18 |
| » Lost to Browns (39-56), 6-1 | League Park I (26-22) | 54-43 | |
| » Starters: Harry Howell vs Red Donahue | Fifth | 4½ out |
| » Defeated Browns (39-57), 8-1 | League Park I (27-22) | 55-43 | |
| » Starters: Willie Sudhoff vs Otto Hess | Fifth | 4½ out |
| Friday, August 19 |
| » Defeated Athletics (56-41), 2-1 | Columbia Park (7-1) | 56-43 | Won 2 |
| » Starters: Earl Moore vs Rube Waddell | Fifth | 4 out |
| Saturday, August 20 |
| » Lost to Athletics (57-41), 2-0 | Columbia Park (7-2) | 56-44 | |
| » Starters: Bill Bernhard vs Weldon Henley | Fifth | 4½ out |
| Monday, August 22 |
| » Lost to Athletics (58-41), 3-1 | Columbia Park (7-3) | 56-45 | Lost 2 |
| » Starters: Bob Rhoads vs Eddie Plank | Fifth | 5 out |
| Tuesday, August 23 |
| » Defeated Athletics (58-42), 4-3 | Columbia Park (8-3) | 57-45 | |
| » Starters: Red Donahue vs Rube Waddell | Fifth | 5 out |
| Wednesday, August 24 |
| » Lost to Senators (24-80), 2-1 | American League Park II (5-3) | 57-46 | |
| » Starters: Otto Hess vs Happy Townsend | Fifth | 6 out |
| Thursday, August 25 |
| » Defeated Senators (24-81), 8-4 | American League Park II (6-3) | 58-46 | |
| » Starters: Bill Bernhard vs Barney Wolfe | Fifth | 6 out |
| Friday, August 26 |
| » Defeated Senators (24-82), 1-0 | American League Park II (7-3) | 59-46 | Won 2 |
| » Starters: Addie Joss vs Casey Patten | Fifth | 6 out |
| Saturday, August 27 |
| » Defeated Senators (24-83), 1-0 | American League Park II (8-3) | 60-46 | Won 3 |
| » Starters: Red Donahue vs Tom Hughes | Fifth | 4½ out |
| Monday, August 29 |
| » Defeated Yankees (65-43), 4-2 | Hilltop Park (4-5) | 61-46 | Won 4 |
| » Starters: Bill Bernhard vs Jack Powell | Fifth | 4½ out |
| Tuesday, August 30 |
| » Lost to Yankees (66-43), 1-0 | Hilltop Park (4-6) | 61-47 | |
| » Starters: Addie Joss vs Al Orth | Fifth | 5½ out |
| Wednesday, August 31 |
| » Lost to Yankees (67-43), 3-1 | Hilltop Park (4-7) | 61-48 | Lost 2 |
| » Starters: Otto Hess vs Jack Chesbro | Fifth | 6½ out |
| Thursday, September 1 |
| » Defeated Red Sox (69-44), 4-1 | Huntington Ave Baseball Grounds (6-2) | 62-48 | |
| » Starters: Bob Rhoads vs Jesse Tannehill | Fifth | 6½ out |
| » Lost to Red Sox (70-44), 5-1 | Huntington Ave Baseball Grounds (6-3) | 62-49 | |
| » Starters: Red Donahue vs Norwood Gibson | Fifth | 6½ out |
| Friday, September 2 |
| » Lost to Red Sox (71-44), 4-3 | Huntington Ave Baseball Grounds (6-4) | 62-50 | Lost 2 |
| » Starters: Bill Bernhard vs Bill Dinneen | Fifth | 7½ out |
| Saturday, September 3 |
| » Defeated Red Sox (71-45), 9-1 | Huntington Ave Baseball Grounds (7-4) | 63-50 | |
| » Starters: Addie Joss vs Cy Young | Fifth | 7 out |
| Monday, September 5 |
| » Defeated Browns (46-67), 4-3 | League Park I (28-22) | 64-50 | Won 2 |
| » Starters: Barney Pelty vs Otto Hess | Fifth | 7½ out |
| » Lost to Browns (47-67), 5-2 | League Park I (28-23) | 64-51 | |
| » Starters: Fred Glade vs Red Donahue | Fifth | 7½ out |
| Tuesday, September 6 |
| » Lost to Browns (48-67), 6-3 | League Park I (28-24) | 64-52 | Lost 2 |
| » Starters: Harry Howell vs Bob Rhoads | Fifth | 8½ out |
| Wednesday, September 7 |
| » Defeated Browns (48-68), 5-1 | League Park I (29-24) | 65-52 | |
| » Starters: Willie Sudhoff vs Bill Bernhard | Fifth | 7½ out |
| Thursday, September 8 |
| » Defeated White Sox (70-53), 6-0 | League Park I (30-24) | 66-52 | Won 2 |
| » Starters: Frank Smith vs Addie Joss | Fifth | 8½ out |
| » Lost to White Sox (71-53), 3-2 | League Park I (30-25) | 66-53 | |
| » Starters: Frank Owen vs Otto Hess | Fifth | 8½ out |
| Friday, September 9 |
| » Defeated White Sox (71-54), 4-0 | League Park I (31-25) | 67-53 | |
| » Starters: Roy Patterson vs Red Donahue | Fifth | 9 out |
| » Lost to White Sox (72-54), 5-3 | League Park I (31-26) | 67-54 | |
| » Starters: Doc White vs Bob Rhoads | Fifth | 9 out |
| Saturday, September 10 |
| » Defeated White Sox (72-55), 5-4 | League Park I (32-26) | 68-54 | |
| » Starters: Nick Altrock vs Bill Bernhard | Fifth | 7½ out |
| » Defeated White Sox (72-56), 11-6 | League Park I (33-26) | 69-54 | Won 2 |
| » Starters: Frank Smith vs Earl Moore | Fifth | 7½ out |
| Monday, September 12 |
| » Lost to White Sox (73-56), 1-0 | South Side Park III (2-7) | 69-55 | |
| » Starters: Addie Joss vs Doc White | Fifth | 8 out |
| Wednesday, September 14 |
| » Lost to White Sox (74-56), 3-1 | South Side Park III (2-8) | 69-56 | Lost 2 |
| » Starters: Red Donahue vs Frank Owen | Fifth | 9 out |
| » Lost to White Sox (75-56), 6-2 | South Side Park III (2-9) | 69-57 | Lost 3 |
| » Starters: Otto Hess vs Roy Patterson | Fifth | 9 out |
| Thursday, September 15 |
| » Tied Tigers, 0-0 | League Park I (33-26) | 69-57 | |
| » Starters: George Mullin vs Bill Bernhard | Fifth | 9 out |
| Friday, September 16 |
| » Lost to Tigers (54-75), 1-0 | League Park I (33-27) | 69-58 | Lost 4 |
| » Starters: Jesse Stovall vs Addie Joss | Fifth | 10 out |
| » Lost to Tigers (55-75), 3-2 | League Park I (33-28) | 69-59 | Lost 5 |
| » Starters: Charlie Jaeger vs Earl Moore | Fifth | 10 out |
| » Major-league debuts: Claude Rossman (Indians) |
| Saturday, September 17 |
| » Lost to Tigers (56-75), 9-5 | League Park I (33-29) | 69-60 | Lost 6 |
| » Starters: Bill Donovan vs Red Donahue | Fifth | 10½ out |
| » Tied Tigers, 0-0 | League Park I (33-29) | 69-60 | |
| » Starters: George Mullin vs Otto Hess | Fifth | 10½ out |
| Monday, September 19 |
| » Lost to Browns (57-74), 5-4 | Sportsman's Park II (4-3) | 69-61 | Lost 7 |
| » Starters: Bill Bernhard vs Willie Sudhoff | Fifth | 11 out |
| » Defeated Browns (57-75), 2-1 | Sportsman's Park II (5-3) | 70-61 | |
| » Starters: Addie Joss vs Barney Pelty | Fifth | 11 out |
| Tuesday, September 20 |
| » Defeated Browns (57-76), 2-1 | Sportsman's Park II (6-3) | 71-61 | Won 2 |
| » Starters: Bob Rhoads vs Harry Howell | Fifth | 12 out |
| » Lost to Browns (58-76), 1-0 | Sportsman's Park II (6-4) | 71-62 | |
| » Starters: Earl Moore vs Ed Siever | Fifth | 12 out |
| Wednesday, September 21 |
| » Defeated Browns (58-77), 9-1 | Sportsman's Park II (7-4) | 72-62 | |
| » Starters: Otto Hess vs Fred Glade | Fifth | 11 out |
| Friday, September 23 |
| » Tied Yankees, 1-1 | League Park I (33-29) | 72-62 | |
| » Starters: Jack Powell vs Bill Bernhard | Fifth | 11 out |
| Monday, September 26 |
| » Defeated Yankees (83-52), 4-3 | League Park I (34-29) | 73-62 | Won 2 |
| » Starters: Jack Chesbro vs Addie Joss | Fifth | 11 out |
| » Defeated Yankees (83-53), 6-2 | League Park I (35-29) | 74-62 | Won 3 |
| » Starters: Jack Powell vs Red Donahue | Fifth | 11 out |
| Tuesday, September 27 |
| » Defeated Red Sox (87-54), 3-1 | League Park I (36-29) | 75-62 | Won 4 |
| » Starters: Norwood Gibson vs Bob Rhoads | Fifth | 10 out |
| Wednesday, September 28 |
| » Defeated Red Sox (87-55), 5-0 | League Park I (37-29) | 76-62 | Won 5 |
| » Starters: Bill Dinneen vs Otto Hess | Fourth | 9 out |
| Thursday, September 29 |
| » Defeated Red Sox (87-56), 3-1 | League Park I (38-29) | 77-62 | Won 6 |
| » Starters: Cy Young vs Bill Bernhard | Fourth | 8 out |
| Friday, September 30 |
| » Defeated Senators (34-107), 3-0 | League Park I (39-29) | 78-62 | Won 7 |
| » Starters: Happy Townsend vs Addie Joss | Fourth | 7 out |
| Saturday, October 1 |
| » Defeated Senators (34-108), 4-0 | League Park I (40-29) | 79-62 | Won 8 |
| » Starters: Tom Hughes vs Red Donahue | Fourth | 6½ out |
| » Defeated Senators (34-109), 9-2 | League Park I (41-29) | 80-62 | Won 9 |
| » Starters: Beany Jacobson vs Bob Rhoads | Fourth | 6½ out |
| Monday, October 3 |
| » Lost to Athletics (77-66), 2-0 | League Park I (41-30) | 80-63 | |
| » Starters: Andy Coakley vs Otto Hess | Fourth | 7½ out |
| » Defeated Athletics (77-67), 7-2 | League Park I (42-30) | 81-63 | |
| » Starters: Fred Applegate vs Bill Bernhard | Fourth | 7½ out |
| Tuesday, October 4 |
| » Lost to Athletics (78-67), 4-0 | League Park I (42-31) | 81-64 | |
| » Starters: Weldon Henley vs Red Donahue | Fourth | 8½ out |
| Thursday, October 6 |
| » Defeated Tigers (61-86), 6-2 | League Park I (43-31) | 82-64 | |
| » Starters: Ed Killian vs Bob Rhoads | Fourth | 8 out |
| » Defeated Tigers (61-87), 8-0 | League Park I (44-31) | 83-64 | Won 2 |
| » Starters: Frank Kitson vs Otto Hess | Fourth | 8 out |
| Friday, October 7 |
| » Defeated Tigers (61-88), 8-1 | Bennett Park (4-3) | 84-64 | Won 3 |
| » Starters: Addie Joss vs Jesse Stovall | Fourth | 7 out |
| » Defeated Tigers (61-89), 9-0 | Bennett Park (5-3) | 85-64 | Won 4 |
| » Starters: Bill Bernhard vs Charlie Jaeger | Fourth | 7 out |
| Saturday, October 8 |
| » Lost to Tigers (62-89), 2-1 | Bennett Park (5-4) | 85-65 | |
| » Starters: Bob Rhoads vs George Mullin | Fourth | 7½ out |
| » Defeated Tigers (62-90), 3-0 | Bennett Park (6-4) | 86-65 | |
| » Starters: Otto Hess vs George Mullin | Fourth | 7½ out |
| Tuesday, November 1 |
| Future Indian Johnny Burnett is born in Bartow, FL. |
| Friday, December 16 |
| Future Indian Joe Berry is born in Huntsville, AR. |
| Sunday, December 25 |
| Future Indian Lloyd Brown is born in Beeville, TX. |
Game information provided by Retrosheet (www.retrosheet.org) |
