| Thursday, April 14 |
| » Defeated Senators (0-1), 8-3 | American League Park II (1-0) | 1-0 | |
| » Starters: Eddie Plank vs Highball Wilson | First | -- |
| Friday, April 15 |
| » Tied Senators, 6-6 | American League Park II (1-0) | 1-0 | |
| » Starters: Weldon Henley vs Casey Patten | First | -- |
| Saturday, April 16 |
| » Defeated Senators (0-2), 12-2 | American League Park II (2-0) | 2-0 | Won 2 |
| » Starters: Rube Waddell vs Happy Townsend | First | -- |
| Monday, April 18 |
| » Defeated Yankees (1-3), 5-1 | Hilltop Park (1-0) | 3-0 | Won 3 |
| » Starters: Chief Bender vs Jack Chesbro | First | -- |
| Tuesday, April 19 |
| » Lost to Yankees (2-3), 5-4 | Hilltop Park (1-1) | 3-1 | |
| » Starters: Eddie Plank vs Tom Hughes | Second | 1 out |
| Thursday, April 21 |
| » Defeated Yankees (2-4), 3-2 | Columbia Park (1-0) | 4-1 | |
| » Starters: Jack Powell vs Rube Waddell | Second | ½ out |
| Friday, April 22 |
| » Lost to Red Sox (6-1), 3-1 | Columbia Park (1-1) | 4-2 | |
| » Starters: Bill Dinneen vs Weldon Henley | Second | 1½ out |
| Saturday, April 23 |
| » Lost to Red Sox (7-1), 3-1 | Columbia Park (1-2) | 4-3 | Lost 2 |
| » Starters: Jesse Tannehill vs Eddie Plank | Second | 2½ out |
| Monday, April 25 |
| » Defeated Red Sox (7-2), 2-0 | Columbia Park (2-2) | 5-3 | |
| » Starters: Cy Young vs Rube Waddell | Second | 1½ out |
| Tuesday, April 26 |
| » Lost to Red Sox (8-2), 2-1 | Columbia Park (2-3) | 5-4 | |
| » Starters: Norwood Gibson vs Weldon Henley | Third | 2½ out |
| Saturday, April 30 |
| » Defeated Yankees (5-5), 6-2 | Columbia Park (3-3) | 6-4 | |
| » Starters: Jack Chesbro vs Eddie Plank | Second | 3 out |
| Monday, May 2 |
| » Defeated Red Sox (10-3), 3-0 | Huntington Ave Baseball Grounds (1-0) | 7-4 | Won 2 |
| » Starters: Rube Waddell vs Jesse Tannehill | Second | 2 out |
| Tuesday, May 3 |
| » Lost to Red Sox (11-3), 4-2 | Huntington Ave Baseball Grounds (1-1) | 7-5 | |
| » Starters: Weldon Henley vs Bill Dinneen | Second | 3 out |
| Wednesday, May 4 |
| » Lost to Red Sox (12-3), 3-2 | Huntington Ave Baseball Grounds (1-2) | 7-6 | Lost 2 |
| » Starters: Eddie Plank vs Norwood Gibson | Third | 4 out |
| Thursday, May 5 |
| » Lost to Red Sox (13-3), 3-0 | Huntington Ave Baseball Grounds (1-3) | 7-7 | Lost 3 |
| » Starters: Rube Waddell vs Cy Young | Fourth | 5 out |
| Friday, May 6 |
| » Defeated Senators (1-14), 16-6 | Columbia Park (4-3) | 8-7 | |
| » Starters: Casey Patten vs Weldon Henley | Second | 5 out |
| Saturday, May 7 |
| » Defeated Senators (1-15), 11-4 | Columbia Park (5-3) | 9-7 | Won 2 |
| » Starters: Beany Jacobson vs Rube Waddell | Second | 4 out |
| Monday, May 9 |
| » Defeated Senators (1-16), 6-3 | Columbia Park (6-3) | 10-7 | Won 3 |
| » Starters: Davey Dunkle vs Eddie Plank | Second | 3½ out |
| Wednesday, May 11 |
| » Defeated White Sox (12-10), 6-5 | Columbia Park (7-3) | 11-7 | Won 4 |
| » Starters: Roy Patterson vs Rube Waddell | Second | 3 out |
| Thursday, May 12 |
| » Defeated White Sox (12-11), 9-3 | Columbia Park (8-3) | 12-7 | Won 5 |
| » Starters: Doc White vs Weldon Henley | Second | 3 out |
| Friday, May 13 |
| » Lost to White Sox (13-11), 3-2 | Columbia Park (8-4) | 12-8 | |
| » Starters: Frank Owen vs Eddie Plank | Second | 4 out |
| Saturday, May 14 |
| » Defeated White Sox (13-12), 2-1 | Columbia Park (9-4) | 13-8 | |
| » Starters: Nick Altrock vs Rube Waddell | Second | 4 out |
| Monday, May 16 |
| » Defeated Browns (9-12), 5-4 | Columbia Park (10-4) | 14-8 | Won 2 |
| » Starters: Ed Siever vs Weldon Henley | Second | 3 out |
| Tuesday, May 17 |
| » Lost to Browns (10-12), 2-0 | Columbia Park (10-5) | 14-9 | |
| » Starters: Harry Howell vs Rube Waddell | Second | 3 out |
| Wednesday, May 18 |
| » Defeated Browns (10-13), 9-4 | Columbia Park (11-5) | 15-9 | |
| » Starters: Cy Morgan vs Eddie Plank | Second | 2½ out |
| Thursday, May 19 |
| » Lost to Browns (11-13), 4-3 | Columbia Park (11-6) | 15-10 | |
| » Starters: Fred Glade vs Chief Bender | Second | 3 out |
| Friday, May 20 |
| » Lost to Indians (13-11), 8-5 | Columbia Park (11-7) | 15-11 | Lost 2 |
| » Starters: Earl Moore vs Weldon Henley | Third | 4 out |
| Saturday, May 21 |
| » Defeated Indians (13-12), 7-0 | Columbia Park (12-7) | 16-11 | |
| » Starters: Bill Bernhard vs Eddie Plank | Second | 3 out |
| Monday, May 23 |
| » Lost to Indians (14-12), 4-3 | Columbia Park (12-8) | 16-12 | |
| » Starters: Red Donahue vs Rube Waddell | Second | 3 out |
| Tuesday, May 24 |
| » Lost to Tigers (11-18), 6-4 | Columbia Park (12-9) | 16-13 | Lost 2 |
| » Starters: Ed Killian vs Chief Bender | Fourth | 4 out |
| Wednesday, May 25 |
| » Defeated Tigers (11-19), 5-4 | Columbia Park (13-9) | 17-13 | |
| » Starters: George Mullin vs Eddie Plank | Third | 4 out |
| Thursday, May 26 |
| » Defeated Tigers (11-20), 5-0 | Columbia Park (14-9) | 18-13 | Won 2 |
| » Starters: Bill Donovan vs Rube Waddell | Third | 3 out |
| Friday, May 27 |
| » Defeated Yankees (17-14), 7-5 | Columbia Park (15-9) | 19-13 | Won 3 |
| » Starters: Clark Griffith vs Weldon Henley | Third | 3 out |
| Saturday, May 28 |
| » Lost to Yankees (18-14), 1-0 | Columbia Park (15-10) | 19-14 | |
| » Starters: Jack Chesbro vs Eddie Plank | Third | 4 out |
| Monday, May 30 |
| » Lost to Yankees (19-14), 7-4 | Hilltop Park (1-2) | 19-15 | Lost 2 |
| » Starters: Chief Bender vs Jack Powell | Third | 5 out |
| » Defeated Yankees (19-15), 1-0 | Hilltop Park (2-2) | 20-15 | |
| » Starters: Rube Waddell vs Tom Hughes | Third | 5 out |
| Wednesday, June 1 |
| » Lost to Browns (16-18), 3-1 | Sportsman's Park II (0-1) | 20-16 | |
| » Starters: Eddie Plank vs Harry Howell | Fourth | 6 out |
| » Major-league debuts: Jim Mullin (Athletics) |
| Saturday, June 4 |
| » Defeated Browns (16-19), 5-2 | Sportsman's Park II (1-1) | 21-16 | |
| » Starters: Eddie Plank vs Fred Glade | Fourth | 5 out |
| Sunday, June 5 |
| » Lost to White Sox (23-18), 14-2 | South Side Park III (0-1) | 21-17 | |
| » Starters: Rube Waddell vs Frank Owen | Fifth | 5½ out |
| Monday, June 6 |
| » Defeated White Sox (23-19), 6-3 | South Side Park III (1-1) | 22-17 | |
| » Starters: Rube Waddell vs Nick Altrock | Third | 5½ out |
| Tuesday, June 7 |
| » Lost to White Sox (24-19), 6-1 | South Side Park III (1-2) | 22-18 | |
| » Starters: Rube Waddell vs Roy Patterson | Fifth | 6½ out |
| Wednesday, June 8 |
| » Lost to White Sox (25-19), 8-2 | South Side Park III (1-3) | 22-19 | Lost 2 |
| » Starters: Eddie Plank vs Frank Owen | Fifth | 6½ out |
| Friday, June 10 |
| » Lost to Indians (23-17), 3-1 | League Park I (0-1) | 22-20 | Lost 3 |
| » Starters: Weldon Henley vs Bill Bernhard | Fifth | 7 out |
| Saturday, June 11 |
| » Defeated Indians (23-18), 1-0 | League Park I (1-1) | 23-20 | |
| » Starters: Eddie Plank vs Bob Rhoads | Fifth | 6 out |
| Monday, June 13 |
| » Defeated Indians (23-19), 9-2 | League Park I (2-1) | 24-20 | Won 2 |
| » Starters: Rube Waddell vs Earl Moore | Fifth | 6½ out |
| Tuesday, June 14 |
| » Defeated Indians (23-20), 4-0 | League Park I (3-1) | 25-20 | Won 3 |
| » Starters: Chief Bender vs Bill Bernhard | Fourth | 6 out |
| Wednesday, June 15 |
| » Lost to Tigers (18-27), 1-0 | Bennett Park (0-1) | 25-21 | |
| » Starters: Weldon Henley vs Bill Donovan | Fifth | 6 out |
| Thursday, June 16 |
| » Lost to Tigers (19-27), 6-5 | Bennett Park (0-2) | 25-22 | Lost 2 |
| » Starters: Eddie Plank vs George Mullin | Fifth | 6 out |
| Friday, June 17 |
| » Defeated Tigers (19-28), 7-1 | Bennett Park (1-2) | 26-22 | |
| » Starters: Rube Waddell vs Ed Killian | Fifth | 5½ out |
| Saturday, June 18 |
| » Lost to Tigers (20-28), 7-3 | Bennett Park (1-3) | 26-23 | |
| » Starters: Chief Bender vs Bill Donovan | Fifth | 6½ out |
| Monday, June 20 |
| » Defeated Senators (9-39), 11-3 | Columbia Park (16-10) | 27-23 | |
| » Starters: Beany Jacobson vs Weldon Henley | Fifth | 6½ out |
| » Major-league debuts: Pete Noonan (Athletics) |
| Wednesday, June 22 |
| » Lost to Red Sox (35-17), 7-6 | Columbia Park (16-11) | 27-24 | |
| » Starters: Cy Young vs Rube Waddell | Fifth | 7½ out |
| Thursday, June 23 |
| » Defeated Red Sox (35-18), 5-1 | Columbia Park (17-11) | 28-24 | |
| » Starters: Norwood Gibson vs Eddie Plank | Fourth | 6½ out |
| Friday, June 24 |
| » Defeated Red Sox (35-19), 8-4 | Columbia Park (18-11) | 29-24 | Won 2 |
| » Starters: Bill Dinneen vs Weldon Henley | Fourth | 5½ out |
| Saturday, June 25 |
| » Defeated Senators (9-44), 6-3 | Columbia Park (19-11) | 30-24 | Won 3 |
| » Starters: Happy Townsend vs Rube Waddell | Fourth | 4½ out |
| Monday, June 27 |
| » Defeated Senators (9-45), 3-2 | American League Park II (3-0) | 31-24 | Won 4 |
| » Starters: Chief Bender vs Beany Jacobson | Fourth | 3½ out |
| Tuesday, June 28 |
| » Lost to Senators (10-45), 2-1 | American League Park II (3-1) | 31-25 | |
| » Starters: Eddie Plank vs Casey Patten | Fourth | 4½ out |
| Thursday, June 30 |
| » Lost to Red Sox (37-21), 4-3 | Huntington Ave Baseball Grounds (1-4) | 31-26 | Lost 2 |
| » Starters: Rube Waddell vs Cy Young | Fourth | 5½ out |
| Friday, July 1 |
| » Defeated Red Sox (37-22), 5-4 | Huntington Ave Baseball Grounds (2-4) | 32-26 | |
| » Starters: Chief Bender vs Jesse Tannehill | Fourth | 4½ out |
| Saturday, July 2 |
| » Lost to Red Sox (38-22), 2-1 | Huntington Ave Baseball Grounds (2-5) | 32-27 | |
| » Starters: Eddie Plank vs George Winter | Fourth | 5½ out |
| Monday, July 4 |
| » Lost to Yankees (37-23), 9-3 | Columbia Park (19-12) | 32-28 | Lost 2 |
| » Starters: Jack Chesbro vs Weldon Henley | Fifth | 7½ out |
| » Lost to Yankees (38-23), 5-2 | Columbia Park (19-13) | 32-29 | Lost 3 |
| » Starters: Clark Griffith vs Rube Waddell | Fifth | 7½ out |
| Tuesday, July 5 |
| » Lost to Yankees (39-23), 6-3 | Hilltop Park (2-3) | 32-30 | Lost 4 |
| » Starters: Chief Bender vs Jack Powell | Fifth | 8½ out |
| Wednesday, July 6 |
| » Lost to Yankees (40-23), 7-1 | Hilltop Park (2-4) | 32-31 | Lost 5 |
| » Starters: Eddie Plank vs Tom Hughes | Fifth | 9½ out |
| Friday, July 8 |
| » Defeated Senators (11-52), 2-1 | Columbia Park (20-13) | 33-31 | |
| » Starters: Happy Townsend vs Eddie Plank | Fifth | 10 out |
| Saturday, July 9 |
| » Defeated Senators (11-53), 3-0 | Columbia Park (21-13) | 34-31 | Won 2 |
| » Starters: Casey Patten vs Rube Waddell | Fifth | 10½ out |
| » Lost to Senators (12-53), 11-3 | Columbia Park (21-14) | 34-32 | |
| » Starters: Al Orth vs Weldon Henley | Fifth | 10½ out |
| Monday, July 11 |
| » Defeated Senators (12-54), 3-1 | Columbia Park (22-14) | 35-32 | |
| » Starters: Beany Jacobson vs Eddie Plank | Fifth | 9½ out |
| Tuesday, July 12 |
| » Defeated White Sox (43-30), 6-4 | Columbia Park (23-14) | 36-32 | Won 2 |
| » Starters: Frank Owen vs Weldon Henley | Fifth | 9½ out |
| Wednesday, July 13 |
| » Defeated White Sox (43-31), 3-0 | Columbia Park (24-14) | 37-32 | Won 3 |
| » Starters: Nick Altrock vs Chief Bender | Fifth | 9½ out |
| Thursday, July 14 |
| » Defeated White Sox (43-32), 2-1 | Columbia Park (25-14) | 38-32 | Won 4 |
| » Starters: Roy Patterson vs Rube Waddell | Fifth | 8½ out |
| Friday, July 15 |
| » Defeated White Sox (43-33), 5-1 | Columbia Park (26-14) | 39-32 | Won 5 |
| » Starters: Doc White vs Eddie Plank | Fourth | 8½ out |
| Saturday, July 16 |
| » Defeated Browns (30-39), 8-1 | Columbia Park (27-14) | 40-32 | Won 6 |
| » Starters: Harry Howell vs Weldon Henley | Fourth | 8½ out |
| Monday, July 18 |
| » Defeated Browns (30-40), 5-4 | Columbia Park (28-14) | 41-32 | Won 7 |
| » Starters: Barney Pelty vs Chief Bender | Fourth | 8½ out |
| Tuesday, July 19 |
| » Lost to Browns (31-40), 1-0 | Columbia Park (28-15) | 41-33 | |
| » Starters: Fred Glade vs Rube Waddell | Fourth | 8½ out |
| Wednesday, July 20 |
| » Defeated Browns (31-41), 2-0 | Columbia Park (29-15) | 42-33 | |
| » Starters: Harry Howell vs Eddie Plank | Fourth | 7 out |
| Thursday, July 21 |
| » Lost to Indians (41-33), 14-8 | Columbia Park (29-16) | 42-34 | |
| » Starters: Red Donahue vs Weldon Henley | Fifth | 7 out |
| Friday, July 22 |
| » Lost to Indians (42-33), 4-0 | Columbia Park (29-17) | 42-35 | Lost 2 |
| » Starters: Bill Bernhard vs Chief Bender | Fifth | 7 out |
| Saturday, July 23 |
| » Lost to Indians (43-33), 3-2 | Columbia Park (29-18) | 42-36 | Lost 3 |
| » Starters: Earl Moore vs Rube Waddell | Fifth | 7½ out |
| » Lost to Indians (44-33), 4-1 | Columbia Park (29-19) | 42-37 | Lost 4 |
| » Starters: Addie Joss vs Eddie Plank | Fifth | 7½ out |
| Tuesday, July 26 |
| » Lost to Tigers (33-46), 2-1 | Columbia Park (29-20) | 42-38 | Lost 5 |
| » Starters: Ed Killian vs Eddie Plank | Fifth | 8 out |
| Wednesday, July 27 |
| » Defeated Tigers (33-47), 5-0 | Columbia Park (30-20) | 43-38 | |
| » Starters: Jesse Stovall vs Rube Waddell | Fifth | 8 out |
| Thursday, July 28 |
| » Defeated Tigers (33-48), 4-0 | Columbia Park (31-20) | 44-38 | Won 2 |
| » Starters: Frank Kitson vs Weldon Henley | Fifth | 7½ out |
| Friday, July 29 |
| » Defeated Tigers (33-49), 2-0 | Columbia Park (32-20) | 45-38 | Won 3 |
| » Starters: George Mullin vs Eddie Plank | Fifth | 6½ out |
| Saturday, July 30 |
| » Defeated Tigers (33-50), 4-1 | Columbia Park (33-20) | 46-38 | Won 4 |
| » Starters: Ed Killian vs Rube Waddell | Fifth | 5½ out |
| Monday, August 1 |
| » Defeated Browns (34-46), 4-0 | Sportsman's Park II (2-1) | 47-38 | Won 5 |
| » Starters: Chief Bender vs Harry Howell | Fifth | 5½ out |
| Tuesday, August 2 |
| » Defeated Browns (34-47), 9-3 | Sportsman's Park II (3-1) | 48-38 | Won 6 |
| » Starters: Rube Waddell vs Barney Pelty | Fifth | 5½ out |
| Wednesday, August 3 |
| » Defeated Browns (34-48), 10-4 | Sportsman's Park II (4-1) | 49-38 | Won 7 |
| » Starters: Weldon Henley vs Ed Siever | Fourth | 5½ out |
| Friday, August 5 |
| » Defeated White Sox (57-36), 4-3 | South Side Park III (2-3) | 50-38 | Won 8 |
| » Starters: Eddie Plank vs Frank Owen | Fourth | 4 out |
| Saturday, August 6 |
| » Lost to White Sox (58-36), 8-1 | South Side Park III (2-4) | 50-39 | |
| » Starters: Chief Bender vs Nick Altrock | Fourth | 5 out |
| Sunday, August 7 |
| » Defeated White Sox (58-37), 5-2 | South Side Park III (3-4) | 51-39 | |
| » Starters: Rube Waddell vs Frank Smith | Fourth | 4½ out |
| Monday, August 8 |
| » Defeated White Sox (58-38), 6-5 | South Side Park III (4-4) | 52-39 | Won 2 |
| » Starters: Eddie Plank vs Frank Owen | Fourth | 3½ out |
| Thursday, August 11 |
| » Defeated Indians (50-41), 2-1 | League Park I (4-1) | 53-39 | Won 3 |
| » Starters: Rube Waddell vs Bill Bernhard | Fourth | 4 out |
| Friday, August 12 |
| » Defeated Indians (50-42), 5-0 | League Park I (5-1) | 54-39 | Won 4 |
| » Starters: Weldon Henley vs Addie Joss | Fourth | 3 out |
| Saturday, August 13 |
| » Lost to Indians (51-42), 7-2 | League Park I (5-2) | 54-40 | |
| » Starters: Eddie Plank vs Red Donahue | Fourth | 3½ out |
| Monday, August 15 |
| » Defeated Tigers (41-56), 2-0 | Bennett Park (2-3) | 55-40 | |
| » Starters: Rube Waddell vs Frank Kitson | Fourth | 3 out |
| Tuesday, August 16 |
| » Defeated Tigers (41-57), 6-3 | Bennett Park (3-3) | 56-40 | Won 2 |
| » Starters: Weldon Henley vs Ed Killian | Fourth | 3 out |
| Wednesday, August 17 |
| » Tied Tigers, 3-3 | Bennett Park (3-3) | 56-40 | |
| » Starters: Eddie Plank vs George Mullin | Fourth | 3½ out |
| Friday, August 19 |
| » Lost to Indians (56-43), 2-1 | Columbia Park (33-21) | 56-41 | |
| » Starters: Earl Moore vs Rube Waddell | Fourth | 3 out |
| Saturday, August 20 |
| » Defeated Indians (56-44), 2-0 | Columbia Park (34-21) | 57-41 | |
| » Starters: Bill Bernhard vs Weldon Henley | Fourth | 3½ out |
| Monday, August 22 |
| » Defeated Indians (56-45), 3-1 | Columbia Park (35-21) | 58-41 | Won 2 |
| » Starters: Bob Rhoads vs Eddie Plank | Fourth | 2 out |
| Tuesday, August 23 |
| » Lost to Indians (57-45), 4-3 | Columbia Park (35-22) | 58-42 | |
| » Starters: Red Donahue vs Rube Waddell | Fourth | 3 out |
| Wednesday, August 24 |
| » Lost to Tigers (46-58), 7-5 | Columbia Park (35-23) | 58-43 | Lost 2 |
| » Starters: Ed Killian vs Weldon Henley | Fourth | 4 out |
| Thursday, August 25 |
| » Lost to Tigers (47-58), 7-2 | Columbia Park (35-24) | 58-44 | Lost 3 |
| » Starters: Frank Kitson vs Rube Waddell | Fourth | 5 out |
| Friday, August 26 |
| » Defeated Tigers (47-59), 7-4 | Columbia Park (36-24) | 59-44 | |
| » Starters: George Mullin vs Chief Bender | Fourth | 5 out |
| Saturday, August 27 |
| » Defeated Tigers (47-60), 4-3 | Columbia Park (37-24) | 60-44 | Won 2 |
| » Starters: Bill Donovan vs Eddie Plank | Fourth | 3½ out |
| Monday, August 29 |
| » Defeated White Sox (64-48), 4-1 | Columbia Park (38-24) | 61-44 | Won 3 |
| » Starters: Nick Altrock vs Rube Waddell | Third | 3½ out |
| Tuesday, August 30 |
| » Lost to White Sox (65-48), 3-0 | Columbia Park (38-25) | 61-45 | |
| » Starters: Roy Patterson vs Weldon Henley | Fourth | 4½ out |
| Wednesday, August 31 |
| » Defeated White Sox (65-49), 1-0 | Columbia Park (39-25) | 62-45 | |
| » Starters: Frank Owen vs Eddie Plank | Third | 4½ out |
| Thursday, September 1 |
| » Lost to Browns (45-65), 2-0 | Columbia Park (39-26) | 62-46 | |
| » Starters: Fred Glade vs Rube Waddell | Third | 5 out |
| Saturday, September 3 |
| » Lost to Browns (46-65), 4-2 | Columbia Park (39-27) | 62-47 | Lost 2 |
| » Starters: Barney Pelty vs Weldon Henley | Third | 5½ out |
| » Defeated Browns (46-66), 5-2 | Columbia Park (40-27) | 63-47 | |
| » Starters: Harry Howell vs Eddie Plank | Third | 5½ out |
| Monday, September 5 |
| » Lost to Yankees (71-43), 2-1 | Hilltop Park (2-5) | 63-48 | |
| » Starters: Andy Coakley vs Jack Chesbro | Fourth | 6 out |
| » Defeated Yankees (71-44), 7-2 | Hilltop Park (3-5) | 64-48 | |
| » Starters: Rube Waddell vs Jack Powell | Fourth | 6 out |
| Tuesday, September 6 |
| » Lost to Yankees (72-44), 5-2 | Hilltop Park (3-6) | 64-49 | |
| » Starters: Rube Waddell vs Al Orth | Fourth | 7½ out |
| » Lost to Yankees (73-44), 2-1 | Hilltop Park (3-7) | 64-50 | Lost 2 |
| » Starters: Weldon Henley vs Clark Griffith | Fourth | 7½ out |
| Wednesday, September 7 |
| » Defeated Yankees (73-45), 3-0 | Columbia Park (41-27) | 65-50 | |
| » Starters: Jack Powell vs Eddie Plank | Fourth | 6½ out |
| Thursday, September 8 |
| » Lost to Yankees (74-45), 3-2 | Columbia Park (41-28) | 65-51 | |
| » Starters: Jack Chesbro vs Rube Waddell | Fourth | 8½ out |
| » Lost to Yankees (75-45), 5-1 | Columbia Park (41-29) | 65-52 | Lost 2 |
| » Starters: Al Orth vs Chief Bender | Fourth | 8½ out |
| Friday, September 9 |
| » Defeated Yankees (75-46), 3-2 | Columbia Park (42-29) | 66-52 | |
| » Starters: Jack Powell vs Weldon Henley | Fourth | 8 out |
| » Defeated Yankees (75-47), 5-1 | Columbia Park (43-29) | 67-52 | Won 2 |
| » Starters: Clark Griffith vs Rube Waddell | Fourth | 8 out |
| Saturday, September 10 |
| » Defeated Red Sox (78-48), 1-0 | Columbia Park (44-29) | 68-52 | Won 3 |
| » Starters: Cy Young vs Eddie Plank | Third | 7 out |
| Monday, September 12 |
| » Lost to Red Sox (79-48), 6-4 | Columbia Park (44-30) | 68-53 | |
| » Starters: Norwood Gibson vs Rube Waddell | Fourth | 7 out |
| » Defeated Red Sox (79-49), 6-2 | Columbia Park (45-30) | 69-53 | |
| » Starters: Bill Dinneen vs Andy Coakley | Fourth | 7 out |
| Tuesday, September 13 |
| » Tied Red Sox, 0-0 | Columbia Park (45-30) | 69-53 | |
| » Starters: Jesse Tannehill vs Weldon Henley | Fourth | 7 out |
| Thursday, September 15 |
| » Defeated Senators (31-97), 8-4 | Columbia Park (46-30) | 70-53 | Won 2 |
| » Starters: Tom Hughes vs Eddie Plank | Fourth | 6 out |
| » Defeated Senators (31-98), 4-3 | Columbia Park (47-30) | 71-53 | Won 3 |
| » Starters: Beany Jacobson vs Rube Waddell | Fourth | 6 out |
| Friday, September 16 |
| » Lost to Senators (32-98), 5-3 | Columbia Park (47-31) | 71-54 | |
| » Starters: Casey Patten vs Weldon Henley | Fourth | 6½ out |
| Saturday, September 17 |
| » Defeated Red Sox (81-52), 4-3 | Huntington Ave Baseball Grounds (3-5) | 72-54 | |
| » Starters: Andy Coakley vs Norwood Gibson | Third | 6 out |
| Monday, September 19 |
| » Defeated Red Sox (81-53), 6-1 | Huntington Ave Baseball Grounds (4-5) | 73-54 | Won 2 |
| » Starters: Eddie Plank vs Jesse Tannehill | Third | 6 out |
| Tuesday, September 20 |
| » Lost to Red Sox (82-53), 11-1 | Huntington Ave Baseball Grounds (4-6) | 73-55 | |
| » Starters: Chief Bender vs Cy Young | Fourth | 7½ out |
| Wednesday, September 21 |
| » Lost to Red Sox (83-53), 5-1 | Huntington Ave Baseball Grounds (4-7) | 73-56 | Lost 2 |
| » Starters: Weldon Henley vs Bill Dinneen | Fourth | 8 out |
| » Lost to Red Sox (84-53), 4-3 | Huntington Ave Baseball Grounds (4-8) | 73-57 | Lost 3 |
| » Starters: Andy Coakley vs Norwood Gibson | Fourth | 8 out |
| Friday, September 23 |
| » Major-league debuts: Bugs Raymond (Tigers) |
| Saturday, September 24 |
| » Lost to White Sox (80-58), 4-0 | South Side Park III (4-5) | 73-58 | Lost 4 |
| » Starters: Eddie Plank vs Roy Patterson | Fourth | 8½ out |
| Sunday, September 25 |
| » Lost to White Sox (81-58), 4-0 | South Side Park III (4-6) | 73-59 | Lost 5 |
| » Starters: Andy Coakley vs Doc White | Fourth | 9 out |
| Monday, September 26 |
| » Defeated White Sox (81-59), 2-1 | South Side Park III (5-6) | 74-59 | |
| » Starters: Eddie Plank vs Roy Patterson | Fourth | 9½ out |
| Tuesday, September 27 |
| » Lost to Browns (60-78), 4-2 | Sportsman's Park II (4-2) | 74-60 | |
| » Starters: Weldon Henley vs Ed Siever | Fourth | 9½ out |
| » Tied Browns, 0-0 | Sportsman's Park II (4-2) | 74-60 | |
| » Starters: Chief Bender vs Willie Sudhoff | Fourth | 9½ out |
| Wednesday, September 28 |
| » Lost to Browns (61-78), 5-1 | Sportsman's Park II (4-3) | 74-61 | Lost 2 |
| » Starters: Andy Coakley vs Harry Howell | Fifth | 10 out |
| » Lost to Browns (62-78), 5-0 | Sportsman's Park II (4-4) | 74-62 | Lost 3 |
| » Starters: Jim Fairbank vs Barney Pelty | Fifth | 10 out |
| Thursday, September 29 |
| » Defeated Browns (62-79), 1-0 | Sportsman's Park II (5-4) | 75-62 | |
| » Starters: Rube Waddell vs Cy Morgan | Fifth | 9½ out |
| » Lost to Browns (63-79), 6-1 | Sportsman's Park II (5-5) | 75-63 | |
| » Starters: Weldon Henley vs Fred Glade | Fifth | 9½ out |
| Friday, September 30 |
| » Defeated Tigers (57-84), 9-4 | Bennett Park (4-3) | 76-63 | |
| » Starters: Eddie Plank vs Ed Killian | Fifth | 9 out |
| » Lost to Tigers (58-84), 5-4 | Bennett Park (4-4) | 76-64 | |
| » Starters: Fred Applegate vs Charlie Jaeger | Fifth | 9 out |
| Saturday, October 1 |
| » Lost to Tigers (59-84), 3-2 | Bennett Park (4-5) | 76-65 | Lost 2 |
| » Starters: Rube Waddell vs Jesse Stovall | Fifth | 10½ out |
| » Lost to Tigers (60-84), 2-1 | Bennett Park (4-6) | 76-66 | Lost 3 |
| » Starters: Chief Bender vs George Mullin | Fifth | 10½ out |
| Monday, October 3 |
| » Defeated Indians (80-63), 2-0 | League Park I (6-2) | 77-66 | |
| » Starters: Andy Coakley vs Otto Hess | Fifth | 11½ out |
| » Lost to Indians (81-63), 7-2 | League Park I (6-3) | 77-67 | |
| » Starters: Fred Applegate vs Bill Bernhard | Fifth | 11½ out |
| Tuesday, October 4 |
| » Defeated Indians (81-64), 4-0 | League Park I (7-3) | 78-67 | |
| » Starters: Weldon Henley vs Red Donahue | Fifth | 11½ out |
| Friday, October 7 |
| » Defeated Senators (35-111), 3-2 | American League Park II (4-1) | 79-67 | Won 2 |
| » Starters: Rube Waddell vs Tom Hughes | Fifth | 12 out |
| » Lost to Senators (36-111), 3-2 | American League Park II (4-2) | 79-68 | |
| » Starters: Chief Bender vs Casey Patten | Fifth | 12 out |
| Saturday, October 8 |
| » Lost to Senators (37-111), 12-5 | American League Park II (4-3) | 79-69 | Lost 2 |
| » Starters: Eddie Plank vs Happy Townsend | Fifth | 12½ out |
| » Defeated Senators (37-112), 2-0 | American League Park II (5-3) | 80-69 | |
| » Starters: Andy Coakley vs Beany Jacobson | Fifth | 12½ out |
| Monday, October 10 |
| » Defeated Senators (37-113), 7-6 | American League Park II (6-3) | 81-69 | Won 2 |
| » Starters: Fred Applegate vs Tom Hughes | Fifth | 12½ out |
| » Lost to Senators (38-113), 4-3 | American League Park II (6-4) | 81-70 | |
| » Starters: Rube Waddell vs Barney Wolfe | Fifth | 12½ out |
Game information provided by Retrosheet (www.retrosheet.org) |