| Monday, January 12 |
| Former Senator Win Mercer dies in San Francisco, CA at the age of 29. |
| Sunday, February 1 |
| Future Senator Carl Reynolds is born in LaRue, TX. |
| Thursday, April 16 |
| » Major-league debuts: Bill Hanlon (Cubs) |
| Monday, April 20 |
| » Major-league debuts: Jake Stahl and George Stone (Red Sox) |
| Wednesday, April 22 |
| » Defeated Yankees (0-1), 3-1 | American League Park II (1-0) | 1-0 | |
| » Starters: Jack Chesbro vs Al Orth | First | -- |
| » Major-league debuts: Rabbit Robinson (Senators) |
| Thursday, April 23 |
| » Lost to Yankees (1-1), 7-2 | American League Park II (1-1) | 1-1 | |
| » Starters: Harry Howell vs Watty Lee | Third | 1 out |
| Friday, April 24 |
| » Defeated Yankees (1-2), 7-1 | American League Park II (2-1) | 2-1 | |
| » Starters: Jesse Tannehill vs Casey Patten | Second | ½ out |
| » Major-league debuts: Monte Beville and Barney Wolfe (Yankees) |
| Saturday, April 25 |
| » Lost to Yankees (2-2), 11-1 | American League Park II (2-2) | 2-2 | |
| » Starters: Jack Chesbro vs Highball Wilson | Third | 1½ out |
| Monday, April 27 |
| » Defeated Red Sox (3-4), 6-3 | American League Park II (3-2) | 3-2 | |
| » Starters: Bill Dinneen vs Al Orth | Second | 1½ out |
| Tuesday, April 28 |
| » Lost to Red Sox (4-4), 11-4 | American League Park II (3-3) | 3-3 | |
| » Starters: Cy Young vs Watty Lee | Fourth | 1½ out |
| Wednesday, April 29 |
| » Defeated Red Sox (4-5), 9-5 | American League Park II (4-3) | 4-3 | |
| » Starters: Norwood Gibson vs Casey Patten | Second | 1½ out |
| » Major-league debuts: Norwood Gibson (Red Sox) |
| Thursday, April 30 |
| » Lost to Yankees (4-4), 6-2 | Hilltop Park (0-1) | 4-4 | |
| » Starters: Happy Townsend vs Jack Chesbro | Fourth | 2 out |
| Friday, May 1 |
| » Lost to Yankees (5-4), 8-3 | Hilltop Park (0-2) | 4-5 | Lost 2 |
| » Starters: Al Orth vs Harry Howell | Sixth | 2 out |
| Saturday, May 2 |
| » Defeated Yankees (5-5), 4-3 | Hilltop Park (1-2) | 5-5 | |
| » Starters: Highball Wilson vs Barney Wolfe | Fourth | 2 out |
| Monday, May 4 |
| » Lost to Red Sox (6-7), 6-4 | Huntington Ave Baseball Grounds (0-1) | 5-6 | |
| » Starters: Casey Patten vs Tom Hughes | Sixth | 2½ out |
| Wednesday, May 6 |
| » Lost to Red Sox (7-7), 6-3 | Huntington Ave Baseball Grounds (0-2) | 5-7 | Lost 2 |
| » Starters: Watty Lee vs Cy Young | Seventh | 4 out |
| Thursday, May 7 |
| » Lost to Athletics (9-7), 19-5 | Columbia Park (0-1) | 5-8 | Lost 3 |
| » Starters: Al Orth vs Chief Bender | Seventh | 5 out |
| Friday, May 8 |
| » Lost to Athletics (10-7), 5-3 | Columbia Park (0-2) | 5-9 | Lost 4 |
| » Starters: Highball Wilson vs Rube Waddell | Eighth | 5 out |
| Saturday, May 9 |
| » Lost to Athletics (11-7), 13-4 | Columbia Park (0-3) | 5-10 | Lost 5 |
| » Starters: Casey Patten vs Eddie Plank | Eighth | 6 out |
| Monday, May 11 |
| » Lost to Browns (7-7), 2-0 | Sportsman's Park II (0-1) | 5-11 | Lost 6 |
| » Starters: Happy Townsend vs Willie Sudhoff | Eighth | 5½ out |
| Tuesday, May 12 |
| » Lost to Browns (8-7), 13-2 | Sportsman's Park II (0-2) | 5-12 | Lost 7 |
| » Starters: Watty Lee vs Red Donahue | Eighth | 6½ out |
| Wednesday, May 13 |
| » Defeated Browns (8-8), 3-0 | Sportsman's Park II (1-2) | 6-12 | |
| » Starters: Al Orth vs Jack Powell | Seventh | 5½ out |
| Thursday, May 14 |
| » Defeated Browns (8-9), 4-3 | Sportsman's Park II (2-2) | 7-12 | Won 2 |
| » Starters: Casey Patten vs Bill Reidy | Eighth | 5½ out |
| Friday, May 15 |
| » Lost to White Sox (14-7), 7-4 | South Side Park III (0-1) | 7-13 | |
| » Starters: Happy Townsend vs Davey Dunkle | Seventh | 6½ out |
| Saturday, May 16 |
| » Lost to White Sox (15-7), 4-3 | South Side Park III (0-2) | 7-14 | Lost 2 |
| » Starters: Highball Wilson vs Frank Owen | Eighth | 7½ out |
| Sunday, May 17 |
| » Defeated White Sox (15-8), 6-2 | South Side Park III (1-2) | 8-14 | |
| » Starters: Casey Patten vs Roy Patterson | Eighth | 6½ out |
| Monday, May 18 |
| » Defeated White Sox (15-9), 7-1 | South Side Park III (2-2) | 9-14 | Won 2 |
| » Starters: Watty Lee vs Doc White | Eighth | 5½ out |
| Tuesday, May 19 |
| » Lost to Indians (11-11), 9-1 | League Park I (0-1) | 9-15 | |
| » Starters: Al Orth vs Gene Wright | Eighth | 6 out |
| Wednesday, May 20 |
| » Lost to Indians (12-11), 5-4 | League Park I (0-2) | 9-16 | Lost 2 |
| » Starters: Highball Wilson vs Addie Joss | Eighth | 6 out |
| Thursday, May 21 |
| » Lost to Indians (13-11), 5-2 | League Park I (0-3) | 9-17 | Lost 3 |
| » Starters: Casey Patten vs Bill Bernhard | Eighth | 6½ out |
| Saturday, May 23 |
| » Lost to Tigers (15-12), 4-3 | Bennett Park (0-1) | 9-18 | Lost 4 |
| » Starters: Watty Lee vs Bill Donovan | Eighth | 7 out |
| Sunday, May 24 |
| » Lost to Tigers (16-12), 5-4 | Ramona Park (0-1) | 9-19 | Lost 5 |
| » Starters: Happy Townsend vs John Deering | Seventh | 7 out |
| Monday, May 25 |
| » Defeated Tigers (16-13), 5-1 | Bennett Park (1-1) | 10-19 | |
| » Starters: Casey Patten vs George Mullin | Eighth | 6½ out |
| Thursday, May 28 |
| » Lost to Red Sox (16-15), 5-4 | Huntington Ave Baseball Grounds (0-3) | 10-20 | |
| » Starters: Highball Wilson vs George Winter | Seventh | 8 out |
| Friday, May 29 |
| » Lost to Red Sox (17-15), 7-2 | Huntington Ave Baseball Grounds (0-4) | 10-21 | Lost 2 |
| » Starters: Watty Lee vs Bill Dinneen | Seventh | 9 out |
| Saturday, May 30 |
| » Lost to Red Sox (18-15), 3-2 | Huntington Ave Baseball Grounds (0-5) | 10-22 | Lost 3 |
| » Starters: Al Orth vs Norwood Gibson | Eighth | 9 out |
| » Lost to Red Sox (19-15), 4-0 | Huntington Ave Baseball Grounds (0-6) | 10-23 | Lost 4 |
| » Starters: Casey Patten vs Cy Young | Eighth | 9 out |
| Monday, June 1 |
| » Lost to Athletics (20-16), 1-0 | American League Park II (4-4) | 10-24 | Lost 5 |
| » Starters: Rube Waddell vs Happy Townsend | Eighth | 9½ out |
| Tuesday, June 2 |
| » Lost to Athletics (21-16), 12-3 | American League Park II (4-5) | 10-25 | Lost 6 |
| » Starters: Chief Bender vs Al Orth | Eighth | 10½ out |
| Wednesday, June 3 |
| » Lost to Athletics (22-16), 5-2 | American League Park II (4-6) | 10-26 | Lost 7 |
| » Starters: Eddie Plank vs Highball Wilson | Eighth | 11½ out |
| Thursday, June 4 |
| » Lost to Browns (20-14), 9-1 | American League Park II (4-7) | 10-27 | Lost 8 |
| » Starters: Willie Sudhoff vs Casey Patten | Eighth | 12½ out |
| Friday, June 5 |
| » Lost to Browns (21-14), 3-1 | American League Park II (4-8) | 10-28 | Lost 9 |
| » Starters: Jack Powell vs Happy Townsend | Eighth | 13½ out |
| Saturday, June 6 |
| » Defeated Browns (21-15), 10-0 | American League Park II (5-8) | 11-28 | |
| » Starters: Bill Reidy vs Watty Lee | Eighth | 13½ out |
| Monday, June 8 |
| » Lost to Indians (20-17), 6-2 | American League Park II (5-9) | 11-29 | |
| » Starters: Addie Joss vs Al Orth | Eighth | 14½ out |
| Tuesday, June 9 |
| » Lost to Indians (21-17), 8-6 | American League Park II (5-10) | 11-30 | Lost 2 |
| » Starters: Gene Wright vs Highball Wilson | Eighth | 14½ out |
| Wednesday, June 10 |
| » Lost to Indians (22-17), 8-6 | American League Park II (5-11) | 11-31 | Lost 3 |
| » Starters: Bill Bernhard vs Casey Patten | Seventh | 14½ out |
| Friday, June 12 |
| » Lost to White Sox (21-20), 11-6 | American League Park II (5-12) | 11-32 | Lost 4 |
| » Starters: Roy Patterson vs Watty Lee | Eighth | 15½ out |
| Saturday, June 13 |
| » Defeated White Sox (21-21), 10-0 | American League Park II (6-12) | 12-32 | |
| » Starters: Doc White vs Al Orth | Eighth | 15½ out |
| Monday, June 15 |
| » Defeated Tigers (20-25), 2-1 | American League Park II (7-12) | 13-32 | Won 2 |
| » Starters: George Mullin vs Casey Patten | Eighth | 15 out |
| Tuesday, June 16 |
| » Defeated Tigers (20-26), 5-1 | American League Park II (8-12) | 14-32 | Won 3 |
| » Starters: Bill Donovan vs Happy Townsend | Eighth | 15 out |
| Friday, June 19 |
| » Lost to Browns (22-21), 4-0 | Sportsman's Park II (2-3) | 14-33 | |
| » Starters: Casey Patten vs Jack Powell | Eighth | 15½ out |
| Saturday, June 20 |
| » Lost to Browns (23-21), 7-6 | Sportsman's Park II (2-4) | 14-34 | Lost 2 |
| » Starters: Al Orth vs Red Donahue | Eighth | 16½ out |
| Sunday, June 21 |
| » Lost to Browns (24-21), 2-1 | Sportsman's Park II (2-5) | 14-35 | Lost 3 |
| » Starters: Happy Townsend vs Willie Sudhoff | Seventh | 16½ out |
| Tuesday, June 23 |
| » Lost to White Sox (24-24), 7-2 | South Side Park III (2-3) | 14-36 | Lost 4 |
| » Starters: Casey Patten vs Roy Patterson | Eighth | 17½ out |
| Wednesday, June 24 |
| » Lost to White Sox (25-24), 4-1 | South Side Park III (2-4) | 14-37 | Lost 5 |
| » Starters: Al Orth vs Frank Owen | Eighth | 17½ out |
| Thursday, June 25 |
| » Lost to Indians (28-24), 4-0 | League Park I (0-4) | 14-38 | Lost 6 |
| » Starters: Happy Townsend vs Earl Moore | Eighth | 18½ out |
| Friday, June 26 |
| » Lost to Indians (29-24), 1-0 | League Park I (0-5) | 14-39 | Lost 7 |
| » Starters: Casey Patten vs Gus Dorner | Eighth | 19 out |
| Saturday, June 27 |
| » Lost to Indians (30-24), 8-0 | League Park I (0-6) | 14-40 | Lost 8 |
| » Starters: Al Orth vs Bill Bernhard | Eighth | 19½ out |
| » Defeated Indians (30-25), 5-2 | League Park I (1-6) | 15-40 | |
| » Starters: Highball Wilson vs Addie Joss | Eighth | 19½ out |
| Monday, June 29 |
| » Lost to Tigers (25-29), 3-0 | Bennett Park (1-2) | 15-41 | |
| » Starters: Casey Patten vs George Mullin | Eighth | 21½ out |
| Tuesday, June 30 |
| » Lost to Tigers (26-29), 8-0 | Bennett Park (1-3) | 15-42 | Lost 2 |
| » Starters: Happy Townsend vs Frank Kitson | Eighth | 21½ out |
| Wednesday, July 1 |
| » Defeated Tigers (26-30), 4-1 | Bennett Park (2-3) | 16-42 | |
| » Starters: Al Orth vs John Deering | Seventh | 21½ out |
| Former Senator Jimmy Cooney, Sr. dies in Cranston, RI at the age of 38. |
| Thursday, July 2 |
| » Lost to Tigers (27-30), 1-0 | Bennett Park (2-4) | 16-43 | |
| » Starters: Highball Wilson vs George Mullin | Eighth | 21½ out |
| Former Senator Ed Delahanty dies in Niagara Falls, ON at the age of 36. |
| Saturday, July 4 |
| » Defeated Indians (32-28), 10-3 | American League Park II (9-12) | 17-43 | |
| » Starters: Gene Wright vs Happy Townsend | Eighth | 22 out |
| Monday, July 6 |
| » Lost to Indians (33-28), 1-0 | American League Park II (9-13) | 17-44 | |
| » Starters: Bill Bernhard vs Casey Patten | Eighth | 23½ out |
| » Lost to Indians (34-28), 3-1 | American League Park II (9-14) | 17-45 | Lost 2 |
| » Starters: Addie Joss vs Highball Wilson | Eighth | 23½ out |
| Tuesday, July 7 |
| » Defeated Indians (34-29), 5-2 | American League Park II (10-14) | 18-45 | |
| » Starters: Gus Dorner vs Al Orth | Eighth | 22½ out |
| Wednesday, July 8 |
| » Lost to Tigers (30-32), 7-5 | American League Park II (10-15) | 18-46 | |
| » Starters: John Deering vs Casey Patten | Eighth | 23½ out |
| Thursday, July 9 |
| » Defeated Tigers (30-33), 17-4 | American League Park II (11-15) | 19-46 | |
| » Starters: George Mullin vs Highball Wilson | Eighth | 23½ out |
| Friday, July 10 |
| » Lost to Tigers (31-33), 10-6 | American League Park II (11-16) | 19-47 | |
| » Starters: Bill Donovan vs Al Orth | Eighth | 23½ out |
| Future Senator Johnny Niggeling is born in Remsen, IA. |
| Saturday, July 11 |
| » Lost to Tigers (32-33), 4-0 | American League Park II (11-17) | 19-48 | Lost 2 |
| » Starters: George Mullin vs Casey Patten | Seventh | 24½ out |
| Monday, July 13 |
| » Defeated Browns (28-36), 4-2 | American League Park II (12-17) | 20-48 | |
| » Starters: Willie Sudhoff vs Watty Lee | Eighth | 24 out |
| Tuesday, July 14 |
| » Lost to Browns (29-36), 4-2 | American League Park II (12-18) | 20-49 | |
| » Starters: Ed Siever vs Al Orth | Eighth | 24 out |
| Wednesday, July 15 |
| » Defeated Browns (29-37), 2-1 | American League Park II (13-18) | 21-49 | |
| » Starters: Jack Powell vs Casey Patten | Eighth | 23½ out |
| Thursday, July 16 |
| » Lost to Browns (30-37), 4-3 | American League Park II (13-19) | 21-50 | |
| » Starters: Roy Evans vs Highball Wilson | Eighth | 24½ out |
| Friday, July 17 |
| » Lost to White Sox (34-36), 6-4 | American League Park II (13-20) | 21-51 | Lost 2 |
| » Starters: Davey Dunkle vs Al Orth | Eighth | 25½ out |
| Saturday, July 18 |
| » Defeated White Sox (34-37), 3-2 | American League Park II (14-20) | 22-51 | |
| » Starters: Roy Patterson vs Casey Patten | Eighth | 25 out |
| » Defeated White Sox (34-38), 3-1 | American League Park II (15-20) | 23-51 | Won 2 |
| » Starters: Patsy Flaherty vs Watty Lee | Eighth | 25 out |
| Monday, July 20 |
| » Defeated White Sox (34-39), 4-3 | American League Park II (16-20) | 24-51 | Won 3 |
| » Starters: Frank Owen vs Highball Wilson | Eighth | 24 out |
| Tuesday, July 21 |
| » Defeated White Sox (34-40), 10-7 | American League Park II (17-20) | 25-51 | Won 4 |
| » Starters: Doc White vs Al Orth | Eighth | 23½ out |
| Wednesday, July 22 |
| » Lost to Athletics (47-32), 3-1 | American League Park II (17-21) | 25-52 | |
| » Starters: Eddie Plank vs Davey Dunkle | Eighth | 24 out |
| Thursday, July 23 |
| » Lost to Athletics (48-32), 11-3 | American League Park II (17-22) | 25-53 | Lost 2 |
| » Starters: Rube Waddell vs Casey Patten | Seventh | 24½ out |
| Friday, July 24 |
| » Defeated Athletics (48-33), 5-4 | American League Park II (18-22) | 26-53 | |
| » Starters: Chief Bender vs Highball Wilson | Eighth | 24½ out |
| Saturday, July 25 |
| » Defeated Athletics (48-34), 2-1 | American League Park II (19-22) | 27-53 | Won 2 |
| » Starters: Rube Waddell vs Davey Dunkle | Eighth | 24½ out |
| Monday, July 27 |
| » Lost to Athletics (49-34), 3-0 | Columbia Park (0-4) | 27-54 | |
| » Starters: Al Orth vs Rube Waddell | Eighth | 25½ out |
| Tuesday, July 28 |
| » Lost to Athletics (50-34), 4-3 | Columbia Park (0-5) | 27-55 | Lost 2 |
| » Starters: Casey Patten vs Eddie Plank | Eighth | 26½ out |
| Wednesday, July 29 |
| » Tied Athletics, 4-4 | Columbia Park (0-5) | 27-55 | |
| » Starters: Highball Wilson vs Weldon Henley | Eighth | 26 out |
| Thursday, July 30 |
| » Lost to Athletics (51-34), 12-1 | Columbia Park (0-6) | 27-56 | Lost 3 |
| » Starters: Davey Dunkle vs Eddie Plank | Eighth | 26½ out |
| » Lost to Athletics (52-34), 6-5 | Columbia Park (0-7) | 27-57 | Lost 4 |
| » Starters: Al Orth vs Rube Waddell | Eighth | 26½ out |
| Friday, July 31 |
| » Tied Red Sox, 4-4 | American League Park II (19-22) | 27-57 | |
| » Starters: Bill Dinneen vs Casey Patten | Eighth | 26½ out |
| Saturday, August 1 |
| » Defeated Red Sox (54-32), 1-0 | American League Park II (20-22) | 28-57 | |
| » Starters: Cy Young vs Highball Wilson | Eighth | 26½ out |
| » Lost to Red Sox (55-32), 5-1 | American League Park II (20-23) | 28-58 | |
| » Starters: Tom Hughes vs Davey Dunkle | Eighth | 26½ out |
| Monday, August 3 |
| » Defeated Red Sox (55-33), 5-2 | American League Park II (21-23) | 29-58 | |
| » Starters: Norwood Gibson vs Al Orth | Seventh | 25½ out |
| Wednesday, August 5 |
| » Lost to Yankees (42-41), 2-1 | American League Park II (21-24) | 29-59 | |
| » Starters: Jack Chesbro vs Casey Patten | Seventh | 26½ out |
| Thursday, August 6 |
| » Lost to Yankees (43-41), 4-0 | American League Park II (21-25) | 29-60 | Lost 2 |
| » Starters: Jesse Tannehill vs Highball Wilson | Eighth | 26½ out |
| Friday, August 7 |
| » Lost to Yankees (44-41), 10-4 | American League Park II (21-26) | 29-61 | Lost 3 |
| » Starters: Harry Howell vs Davey Dunkle | Seventh | 27½ out |
| Saturday, August 8 |
| » Lost to Yankees (45-41), 7-2 | Hilltop Park (1-3) | 29-62 | Lost 4 |
| » Starters: Casey Patten vs Clark Griffith | Eighth | 28½ out |
| Monday, August 10 |
| » Lost to Yankees (46-41), 6-1 | Hilltop Park (1-4) | 29-63 | Lost 5 |
| » Starters: Highball Wilson vs Jack Chesbro | Eighth | 29½ out |
| Tuesday, August 11 |
| » Lost to Yankees (47-41), 16-2 | Hilltop Park (1-5) | 29-64 | Lost 6 |
| » Starters: Al Orth vs Harry Howell | Eighth | 30½ out |
| Friday, August 14 |
| » Defeated Browns (42-50), 1-0 | Sportsman's Park II (3-5) | 30-64 | |
| » Starters: Watty Lee vs Jack Powell | Eighth | 31 out |
| » Lost to Browns (43-50), 7-2 | Sportsman's Park II (3-6) | 30-65 | |
| » Starters: Al Orth vs Willie Sudhoff | Eighth | 31 out |
| Saturday, August 15 |
| » Defeated Browns (43-51), 5-1 | Sportsman's Park II (4-6) | 31-65 | |
| » Starters: Davey Dunkle vs Gene Wright | Eighth | 31 out |
| Sunday, August 16 |
| » Lost to White Sox (44-54), 2-0 | South Side Park III (2-5) | 31-66 | |
| » Starters: Watty Lee vs Frank Owen | Eighth | 32 out |
| » Lost to White Sox (45-54), 3-1 | South Side Park III (2-6) | 31-67 | Lost 2 |
| » Starters: Happy Townsend vs Doc White | Eighth | 32 out |
| Monday, August 17 |
| » Defeated White Sox (45-55), 2-1 | South Side Park III (3-6) | 32-67 | |
| » Starters: Al Orth vs Frank Owen | Eighth | 31 out |
| Tuesday, August 18 |
| » Lost to White Sox (46-55), 3-1 | South Side Park III (3-7) | 32-68 | |
| » Starters: Highball Wilson vs Roy Patterson | Eighth | 32 out |
| Wednesday, August 19 |
| » Lost to Indians (56-46), 2-0 | League Park I (1-7) | 32-69 | Lost 2 |
| » Starters: Davey Dunkle vs Earl Moore | Eighth | 33 out |
| Thursday, August 20 |
| » Lost to Indians (57-46), 5-1 | League Park I (1-8) | 32-70 | Lost 3 |
| » Starters: Al Orth vs Addie Joss | Eighth | 33 out |
| Friday, August 21 |
| » Lost to Indians (58-46), 10-0 | League Park I (1-9) | 32-71 | Lost 4 |
| » Starters: Highball Wilson vs Red Donahue | Eighth | 34 out |
| Saturday, August 22 |
| » Lost to Tigers (53-50), 3-0 | Bennett Park (2-5) | 32-72 | Lost 5 |
| » Starters: Casey Patten vs George Mullin | Eighth | 34 out |
| Monday, August 24 |
| » Defeated Tigers (53-51), 6-4 | Bennett Park (3-5) | 33-72 | |
| » Starters: Watty Lee vs Rube Kisinger | Eighth | 33½ out |
| » Defeated Tigers (53-52), 3-2 | Bennett Park (4-5) | 34-72 | Won 2 |
| » Starters: Highball Wilson vs Frank Kitson | Eighth | 33½ out |
| Wednesday, August 26 |
| » Defeated Yankees (52-52), 2-1 | Hilltop Park (2-5) | 35-72 | Won 3 |
| » Starters: Davey Dunkle vs Jesse Tannehill | Eighth | 33½ out |
| Thursday, August 27 |
| » Lost to Yankees (53-52), 6-5 | Hilltop Park (2-6) | 35-73 | |
| » Starters: Al Orth vs Jack Chesbro | Eighth | 34½ out |
| Saturday, August 29 |
| » Lost to Red Sox (71-39), 3-2 | American League Park II (21-27) | 35-74 | Lost 2 |
| » Starters: Cy Young vs Watty Lee | Eighth | 35½ out |
| » Tied Red Sox, 1-1 | American League Park II (21-27) | 35-74 | |
| » Starters: George Winter vs Highball Wilson | Eighth | 35½ out |
| Monday, August 31 |
| » Defeated Red Sox (71-40), 2-1 | American League Park II (22-27) | 36-74 | |
| » Starters: Bill Dinneen vs Casey Patten | Eighth | 35½ out |
| » Lost to Red Sox (72-40), 5-2 | American League Park II (22-28) | 36-75 | |
| » Starters: Norwood Gibson vs Davey Dunkle | Eighth | 35½ out |
| Tuesday, September 1 |
| » Lost to Red Sox (73-40), 2-1 | American League Park II (22-29) | 36-76 | Lost 2 |
| » Starters: Tom Hughes vs Al Orth | Eighth | 36½ out |
| Wednesday, September 2 |
| » Lost to Yankees (55-52), 11-3 | American League Park II (22-30) | 36-77 | Lost 3 |
| » Starters: Jack Chesbro vs Watty Lee | Seventh | 37 out |
| Thursday, September 3 |
| » Lost to Yankees (56-52), 3-1 | American League Park II (22-31) | 36-78 | Lost 4 |
| » Starters: Jesse Tannehill vs Highball Wilson | Eighth | 38 out |
| Friday, September 4 |
| » Defeated Yankees (56-53), 8-1 | American League Park II (23-31) | 37-78 | |
| » Starters: Harry Howell vs Casey Patten | Eighth | 37½ out |
| Saturday, September 5 |
| » Lost to Yankees (57-53), 10-3 | Hilltop Park (2-7) | 37-79 | |
| » Starters: Davey Dunkle vs Barney Wolfe | Seventh | 38½ out |
| Monday, September 7 |
| » Lost to Athletics (61-54), 6-0 | Columbia Park (0-8) | 37-80 | Lost 2 |
| » Starters: Al Orth vs Eddie Plank | Eighth | 39½ out |
| » Lost to Athletics (62-54), 3-2 | Columbia Park (0-9) | 37-81 | Lost 3 |
| » Starters: Highball Wilson vs Weldon Henley | Eighth | 39½ out |
| Wednesday, September 9 |
| » Lost to Red Sox (77-42), 9-4 | Huntington Ave Baseball Grounds (0-7) | 37-82 | Lost 4 |
| » Starters: Casey Patten vs Tom Hughes | Eighth | 41 out |
| » Lost to Red Sox (78-42), 3-2 | Huntington Ave Baseball Grounds (0-8) | 37-83 | Lost 5 |
| » Starters: Watty Lee vs George Winter | Eighth | 41 out |
| Thursday, September 10 |
| » Lost to Red Sox (79-42), 3-0 | Huntington Ave Baseball Grounds (0-9) | 37-84 | Lost 6 |
| » Starters: Al Orth vs Cy Young | Eighth | 42 out |
| Friday, September 11 |
| » Lost to Red Sox (80-42), 2-1 | Huntington Ave Baseball Grounds (0-10) | 37-85 | Lost 7 |
| » Starters: Davey Dunkle vs Norwood Gibson | Eighth | 43 out |
| Saturday, September 12 |
| » Lost to Athletics (65-56), 5-3 | American League Park II (23-32) | 37-86 | Lost 8 |
| » Starters: Chief Bender vs Highball Wilson | Eighth | 44 out |
| Monday, September 14 |
| » Lost to Athletics (66-56), 13-1 | American League Park II (23-33) | 37-87 | Lost 9 |
| » Starters: Weldon Henley vs Casey Patten | Eighth | 44 out |
| Tuesday, September 15 |
| » Defeated Athletics (66-57), 4-2 | American League Park II (24-33) | 38-87 | |
| » Starters: Eddie Plank vs Al Orth | Eighth | 44 out |
| Wednesday, September 16 |
| » Defeated Tigers (61-63), 10-8 | American League Park II (25-33) | 39-87 | Won 2 |
| » Starters: Bill Donovan vs Watty Lee | Eighth | 44 out |
| Friday, September 18 |
| » Defeated Tigers (61-64), 4-0 | American League Park II (26-33) | 40-87 | Won 3 |
| » Starters: Rube Kisinger vs Highball Wilson | Eighth | 44 out |
| » Defeated Tigers (61-65), 6-5 | American League Park II (27-33) | 41-87 | Won 4 |
| » Starters: Frank Kitson vs Casey Patten | Eighth | 44 out |
| » Major-league debuts: Champ Osteen (Senators) Simon Nicholls (Tigers) |
| Saturday, September 19 |
| » Lost to Browns (62-66), 9-1 | American League Park II (27-34) | 41-88 | |
| » Starters: Barney Pelty vs Watty Lee | Eighth | 45 out |
| Monday, September 21 |
| » Defeated Browns (62-67), 6-4 | American League Park II (28-34) | 42-88 | |
| » Starters: Gene Wright vs Davey Dunkle | Eighth | 45 out |
| Tuesday, September 22 |
| » Lost to Browns (63-67), 8-2 | American League Park II (28-35) | 42-89 | |
| » Starters: Willie Sudhoff vs Casey Patten | Eighth | 45 out |
| Wednesday, September 23 |
| » Defeated Indians (74-61), 7-5 | American League Park II (29-35) | 43-89 | |
| » Starters: Ed Killian vs Happy Townsend | Eighth | 43½ out |
| Thursday, September 24 |
| » Lost to Indians (75-61), 12-2 | American League Park II (29-36) | 43-90 | |
| » Starters: Red Donahue vs Al Orth | Eighth | 44½ out |
| Friday, September 25 |
| » Lost to Indians (76-61), 14-5 | American League Park II (29-37) | 43-91 | Lost 2 |
| » Starters: Martin Glendon vs Davey Dunkle | Eighth | 45 out |
| Saturday, September 26 |
| » Lost to White Sox (58-77), 7-4 | American League Park II (29-38) | 43-92 | Lost 3 |
| » Starters: Frank Owen vs Casey Patten | Eighth | 45½ out |
| Sunday, September 27 |
| » Major-league debuts: George Moriarty (Cubs) |
| Monday, September 28 |
| » Lost to White Sox (59-77), 6-5 | American League Park II (29-39) | 43-93 | Lost 4 |
| » Starters: Roy Patterson vs Watty Lee | Eighth | 47½ out |
| » Lost to White Sox (60-77), 10-3 | American League Park II (29-40) | 43-94 | Lost 5 |
| » Starters: Nick Altrock vs Highball Wilson | Eighth | 47½ out |
| Future Senator Jim Brillheart is born in Dublin, VA. |
| Monday, November 2 |
| Future Senator Chief Hogsett is born in Brownell, KS. |
| Wednesday, November 25 |
| Future Senator Jim Weaver is born in Obion County, TN. |
Game information provided by Retrosheet (www.retrosheet.org) |
