| Thursday, March 5 |
| Future Indian Chick Autry is born in Martindale, TX. |
| Thursday, April 16 |
| » Major-league debuts: Bill Hanlon (Cubs) |
| Monday, April 20 |
| » Major-league debuts: Jake Stahl and George Stone (Red Sox) |
| Wednesday, April 22 |
| » Lost to Tigers (1-0), 4-2 | Bennett Park (0-1) | 0-1 | |
| » Starters: Addie Joss vs George Mullin | Fourth | 1 out |
| Thursday, April 23 |
| » Lost to Tigers (2-0), 11-1 | Bennett Park (0-2) | 0-2 | Lost 2 |
| » Starters: Bill Bernhard vs Bill Donovan | Fifth | 2 out |
| » Major-league debuts: Doc Gessler (Tigers) |
| Saturday, April 25 |
| » Lost to Tigers (3-0), 2-0 | Bennett Park (0-3) | 0-3 | Lost 3 |
| » Starters: Earl Moore vs Mal Eason | Sixth | 3 out |
| » Major-league debuts: Fred Abbott (Indians) |
| Tuesday, April 28 |
| » Defeated Browns (1-3), 6-3 | League Park I (1-0) | 1-3 | |
| » Starters: Jack Powell vs Addie Joss | Seventh | 2½ out |
| Wednesday, April 29 |
| » Defeated Browns (1-4), 4-1 | League Park I (2-0) | 2-3 | Won 2 |
| » Starters: Red Donahue vs Bill Bernhard | Seventh | 2½ out |
| Friday, May 1 |
| » Lost to Browns (2-4), 9-8 | League Park I (2-1) | 2-4 | |
| » Starters: Willie Sudhoff vs Ed Walker | Seventh | 2½ out |
| Saturday, May 2 |
| » Lost to White Sox (5-3), 16-6 | South Side Park III (0-1) | 2-5 | Lost 2 |
| » Starters: Gene Wright vs Doc White | Sixth | 3½ out |
| Sunday, May 3 |
| » Lost to White Sox (6-3), 6-3 | South Side Park III (0-2) | 2-6 | Lost 3 |
| » Starters: Addie Joss vs Nixey Callahan | Sixth | 3½ out |
| Monday, May 4 |
| » Lost to Browns (4-5), 6-1 | Sportsman's Park II (0-1) | 2-7 | Lost 4 |
| » Starters: Earl Moore vs Jack Powell | Eighth | 4½ out |
| Thursday, May 7 |
| » Defeated Tigers (6-7), 6-5 | League Park I (3-1) | 3-7 | |
| » Starters: George Mullin vs Bill Bernhard | Eighth | 5½ out |
| Friday, May 8 |
| » Defeated Tigers (6-8), 7-6 | League Park I (4-1) | 4-7 | Won 2 |
| » Starters: Frank Kitson vs Addie Joss | Seventh | 4½ out |
| Saturday, May 9 |
| » Lost to Tigers (7-8), 13-1 | League Park I (4-2) | 4-8 | |
| » Starters: Bill Donovan vs Gus Dorner | Seventh | 5½ out |
| Sunday, May 10 |
| » Defeated Tigers (7-9), 6-2 | Mahaffey Park (1-0) | 5-8 | |
| » Starters: Mal Eason vs Earl Moore | Seventh | 4½ out |
| Monday, May 11 |
| » Defeated Red Sox (9-9), 6-5 | League Park I (5-2) | 6-8 | Won 2 |
| » Starters: Tom Hughes vs Bill Bernhard | Sixth | 3½ out |
| Tuesday, May 12 |
| » Lost to Red Sox (10-9), 10-5 | League Park I (5-3) | 6-9 | |
| » Starters: Bill Dinneen vs Gene Wright | Seventh | 4½ out |
| Wednesday, May 13 |
| » Defeated Red Sox (10-10), 2-1 | League Park I (6-3) | 7-9 | |
| » Starters: Cy Young vs Addie Joss | Sixth | 3½ out |
| Thursday, May 14 |
| » Lost to Red Sox (11-10), 10-4 | League Park I (6-4) | 7-10 | |
| » Starters: Norwood Gibson vs Earl Moore | Seventh | 4½ out |
| Friday, May 15 |
| » Defeated Yankees (9-12), 5-3 | League Park I (7-4) | 8-10 | |
| » Starters: Jesse Tannehill vs Gene Wright | Fifth | 4½ out |
| Saturday, May 16 |
| » Lost to Yankees (10-12), 3-2 | League Park I (7-5) | 8-11 | |
| » Starters: Jack Chesbro vs Bill Bernhard | Seventh | 5½ out |
| Sunday, May 17 |
| » Defeated Yankees (10-13), 9-2 | Neil Park I (1-0) | 9-11 | |
| » Starters: Clark Griffith vs Addie Joss | Sixth | 4½ out |
| Monday, May 18 |
| » Defeated Yankees (10-14), 7-3 | League Park I (8-5) | 10-11 | Won 2 |
| » Starters: Snake Wiltse vs Earl Moore | Sixth | 3½ out |
| Tuesday, May 19 |
| » Defeated Senators (9-15), 9-1 | League Park I (9-5) | 11-11 | Won 3 |
| » Starters: Al Orth vs Gene Wright | Fourth | 3 out |
| Wednesday, May 20 |
| » Defeated Senators (9-16), 5-4 | League Park I (10-5) | 12-11 | Won 4 |
| » Starters: Highball Wilson vs Addie Joss | Third | 2 out |
| Thursday, May 21 |
| » Defeated Senators (9-17), 5-2 | League Park I (11-5) | 13-11 | Won 5 |
| » Starters: Casey Patten vs Bill Bernhard | Second | 1½ out |
| Saturday, May 23 |
| » Lost to Athletics (16-13), 4-2 | League Park I (11-6) | 13-12 | |
| » Starters: Rube Waddell vs Addie Joss | Fourth | 2 out |
| Monday, May 25 |
| » Defeated Athletics (16-14), 2-1 | League Park I (12-6) | 14-12 | |
| » Starters: Eddie Plank vs Earl Moore | Third | 1 out |
| Tuesday, May 26 |
| » Lost to Athletics (17-14), 8-2 | League Park I (12-7) | 14-13 | |
| » Starters: Rube Waddell vs Gene Wright | Fourth | 2 out |
| Wednesday, May 27 |
| » Lost to White Sox (18-12), 1-0 | League Park I (12-8) | 14-14 | Lost 2 |
| » Starters: Patsy Flaherty vs Bill Bernhard | Fourth | 3 out |
| Friday, May 29 |
| » Lost to White Sox (19-12), 3-2 | League Park I (12-9) | 14-15 | Lost 3 |
| » Starters: Doc White vs Addie Joss | Sixth | 4 out |
| Saturday, May 30 |
| » Defeated White Sox (19-13), 3-2 | League Park I (13-9) | 15-15 | |
| » Starters: Frank Owen vs Earl Moore | Fifth | 2 out |
| » Defeated White Sox (19-14), 15-4 | League Park I (14-9) | 16-15 | Won 2 |
| » Starters: Patsy Flaherty vs Bill Bernhard | Fifth | 2 out |
| Sunday, May 31 |
| » Defeated White Sox (19-15), 4-1 | South Side Park III (1-2) | 17-15 | Won 3 |
| » Starters: Ed Walker vs Roy Patterson | Fourth | 1 out |
| Tuesday, June 2 |
| » Lost to White Sox (20-15), 3-2 | South Side Park III (1-3) | 17-16 | |
| » Starters: Addie Joss vs Doc White | Fifth | 2½ out |
| Thursday, June 4 |
| » Defeated Yankees (15-22), 6-3 | Hilltop Park (1-0) | 18-16 | |
| » Starters: Earl Moore vs Jack Chesbro | Fifth | 3 out |
| Friday, June 5 |
| » Lost to Yankees (16-22), 8-7 | Hilltop Park (1-1) | 18-17 | |
| » Starters: Gus Dorner vs Jesse Tannehill | Fifth | 4 out |
| Saturday, June 6 |
| » Defeated Yankees (16-23), 8-4 | Hilltop Park (2-1) | 19-17 | |
| » Starters: Bill Bernhard vs Jesse Tannehill | Fourth | 4 out |
| Monday, June 8 |
| » Defeated Senators (11-29), 6-2 | American League Park II (1-0) | 20-17 | Won 2 |
| » Starters: Addie Joss vs Al Orth | Fourth | 4 out |
| Tuesday, June 9 |
| » Defeated Senators (11-30), 8-6 | American League Park II (2-0) | 21-17 | Won 3 |
| » Starters: Gene Wright vs Highball Wilson | Fourth | 3 out |
| Wednesday, June 10 |
| » Defeated Senators (11-31), 8-6 | American League Park II (3-0) | 22-17 | Won 4 |
| » Starters: Bill Bernhard vs Casey Patten | Third | 2 out |
| Thursday, June 11 |
| » Defeated Athletics (26-18), 3-2 | Columbia Park (1-0) | 23-17 | Won 5 |
| » Starters: Earl Moore vs Weldon Henley | Third | 2 out |
| Friday, June 12 |
| » Lost to Athletics (27-18), 2-1 | Columbia Park (1-1) | 23-18 | |
| » Starters: Addie Joss vs Rube Waddell | Third | 2½ out |
| Saturday, June 13 |
| » Lost to Athletics (28-18), 12-1 | Columbia Park (1-2) | 23-19 | Lost 2 |
| » Starters: Gus Dorner vs Chief Bender | Third | 3½ out |
| Tuesday, June 16 |
| » Defeated Red Sox (28-18), 7-0 | Huntington Ave Baseball Grounds (1-0) | 24-19 | |
| » Starters: Gus Dorner vs Bill Dinneen | Third | 3½ out |
| Wednesday, June 17 |
| » Defeated Red Sox (28-19), 3-1 | Huntington Ave Baseball Grounds (2-0) | 25-19 | Won 2 |
| » Starters: Earl Moore vs Norwood Gibson | Third | 4 out |
| » Lost to Red Sox (29-19), 6-1 | Huntington Ave Baseball Grounds (2-1) | 25-20 | |
| » Starters: Addie Joss vs Tom Hughes | Third | 4 out |
| Thursday, June 18 |
| » Defeated Red Sox (29-20), 5-4 | League Park I (15-9) | 26-20 | |
| » Starters: George Winter vs Bill Bernhard | Third | 3½ out |
| Friday, June 19 |
| » Lost to Red Sox (30-20), 5-3 | League Park I (15-10) | 26-21 | |
| » Starters: Bill Dinneen vs Gene Wright | Third | 3½ out |
| Saturday, June 20 |
| » Lost to Red Sox (31-20), 5-4 | League Park I (15-11) | 26-22 | Lost 2 |
| » Starters: Norwood Gibson vs Earl Moore | Third | 4½ out |
| Sunday, June 21 |
| » Lost to Red Sox (32-20), 12-7 | Mahaffey Park (1-1) | 26-23 | Lost 3 |
| » Starters: Tom Hughes vs Ed Walker | Third | 4½ out |
| Wednesday, June 24 |
| » Lost to Yankees (22-24), 6-3 | League Park I (15-12) | 26-24 | Lost 4 |
| » Starters: Jack Chesbro vs Bill Bernhard | Fourth | 4½ out |
| » Defeated Yankees (22-25), 3-0 | League Park I (16-12) | 27-24 | |
| » Starters: Clark Griffith vs Addie Joss | Fourth | 4½ out |
| Thursday, June 25 |
| » Defeated Senators (14-38), 4-0 | League Park I (17-12) | 28-24 | Won 2 |
| » Starters: Happy Townsend vs Earl Moore | Fourth | 4½ out |
| Friday, June 26 |
| » Defeated Senators (14-39), 1-0 | League Park I (18-12) | 29-24 | Won 3 |
| » Starters: Casey Patten vs Gus Dorner | Third | 4 out |
| Saturday, June 27 |
| » Defeated Senators (14-40), 8-0 | League Park I (19-12) | 30-24 | Won 4 |
| » Starters: Al Orth vs Bill Bernhard | Third | 4½ out |
| » Lost to Senators (15-40), 5-2 | League Park I (19-13) | 30-25 | |
| » Starters: Highball Wilson vs Addie Joss | Third | 4½ out |
| Monday, June 29 |
| » Lost to Athletics (35-24), 4-2 | League Park I (19-14) | 30-26 | Lost 2 |
| » Starters: Eddie Plank vs Earl Moore | Third | 6½ out |
| Tuesday, June 30 |
| » Defeated Athletics (35-25), 4-3 | League Park I (20-14) | 31-26 | |
| » Starters: Rube Waddell vs Bill Bernhard | Third | 5½ out |
| Wednesday, July 1 |
| » Lost to Athletics (36-25), 9-8 | League Park I (20-15) | 31-27 | |
| » Starters: Weldon Henley vs Addie Joss | Third | 6½ out |
| Thursday, July 2 |
| » Defeated Athletics (36-26), 11-6 | League Park I (21-15) | 32-27 | |
| » Starters: Chief Bender vs Gus Dorner | Third | 5½ out |
| Saturday, July 4 |
| » Lost to Senators (17-43), 10-3 | American League Park II (3-1) | 32-28 | |
| » Starters: Gene Wright vs Happy Townsend | Third | 7 out |
| Monday, July 6 |
| » Defeated Senators (17-44), 1-0 | American League Park II (4-1) | 33-28 | |
| » Starters: Bill Bernhard vs Casey Patten | Third | 6½ out |
| » Defeated Senators (17-45), 3-1 | American League Park II (5-1) | 34-28 | Won 2 |
| » Starters: Addie Joss vs Highball Wilson | Third | 6½ out |
| Tuesday, July 7 |
| » Lost to Senators (18-45), 5-2 | American League Park II (5-2) | 34-29 | |
| » Starters: Gus Dorner vs Al Orth | Third | 6½ out |
| Wednesday, July 8 |
| » Lost to Athletics (39-28), 4-3 | Columbia Park (1-3) | 34-30 | Lost 2 |
| » Starters: Earl Moore vs Chief Bender | Third | 7½ out |
| Future Indian Clint Brown is born in Blackash, PA. |
| Thursday, July 9 |
| » Lost to Athletics (40-28), 9-8 | Columbia Park (1-4) | 34-31 | Lost 3 |
| » Starters: Gene Wright vs Eddie Plank | Third | 8½ out |
| Friday, July 10 |
| » Defeated Athletics (40-29), 4-1 | Columbia Park (2-4) | 35-31 | |
| » Starters: Addie Joss vs Andy Coakley | Third | 7½ out |
| Saturday, July 11 |
| » Defeated Athletics (40-30), 10-3 | Columbia Park (3-4) | 36-31 | Won 2 |
| » Starters: Bill Bernhard vs Rube Waddell | Third | 7½ out |
| Tuesday, July 14 |
| » Defeated Red Sox (45-26), 4-3 | Huntington Ave Baseball Grounds (3-1) | 37-31 | Won 3 |
| » Starters: Earl Moore vs Bill Dinneen | Third | 6½ out |
| Wednesday, July 15 |
| » Lost to Red Sox (46-26), 4-3 | Huntington Ave Baseball Grounds (3-2) | 37-32 | |
| » Starters: Addie Joss vs Tom Hughes | Third | 6½ out |
| » Defeated Red Sox (46-27), 4-2 | Huntington Ave Baseball Grounds (4-2) | 38-32 | |
| » Starters: Bill Bernhard vs George Winter | Third | 6½ out |
| Thursday, July 16 |
| » Lost to Red Sox (47-27), 11-4 | Huntington Ave Baseball Grounds (4-3) | 38-33 | |
| » Starters: Gus Dorner vs Tom Hughes | Third | 7½ out |
| Friday, July 17 |
| » Defeated Yankees (34-34), 11-4 | Hilltop Park (3-1) | 39-33 | |
| » Starters: Earl Moore vs Jack Chesbro | Third | 7½ out |
| Monday, July 20 |
| » Lost to Yankees (35-34), 7-3 | Hilltop Park (3-2) | 39-34 | |
| » Starters: Addie Joss vs Clark Griffith | Third | 7½ out |
| » Defeated Yankees (35-35), 2-0 | Hilltop Park (4-2) | 40-34 | |
| » Starters: Bill Bernhard vs Barney Wolfe | Third | 7½ out |
| Tuesday, July 21 |
| » Lost to Yankees (36-35), 9-3 | Hilltop Park (4-3) | 40-35 | |
| » Starters: Gene Wright vs Harry Howell | Third | 8 out |
| Wednesday, July 22 |
| » Defeated Browns (31-41), 7-0 | League Park I (22-15) | 41-35 | |
| » Starters: Roy Evans vs Earl Moore | Third | 7½ out |
| Thursday, July 23 |
| » Defeated Browns (31-42), 2-0 | League Park I (23-15) | 42-35 | Won 2 |
| » Starters: Ed Siever vs Addie Joss | Third | 7 out |
| Friday, July 24 |
| » Lost to Browns (32-42), 2-0 | League Park I (23-16) | 42-36 | |
| » Starters: Willie Sudhoff vs Bill Bernhard | Third | 8 out |
| Saturday, July 25 |
| » Defeated Browns (32-43), 7-4 | League Park I (24-16) | 43-36 | |
| » Starters: Jack Powell vs Alex Pearson | Third | 8 out |
| Sunday, July 26 |
| » Lost to Browns (33-43), 5-3 | Sportsman's Park II (0-2) | 43-37 | |
| » Starters: Gene Wright vs Ed Siever | Third | 8½ out |
| Monday, July 27 |
| » Lost to Browns (34-43), 9-5 | Sportsman's Park II (0-3) | 43-38 | Lost 2 |
| » Starters: Addie Joss vs Willie Sudhoff | Third | 9½ out |
| Tuesday, July 28 |
| » Defeated Browns (34-44), 10-2 | Sportsman's Park II (1-3) | 44-38 | |
| » Starters: Earl Moore vs Jack Powell | Third | 9½ out |
| Thursday, July 30 |
| » Lost to White Sox (37-44), 10-0 | South Side Park III (1-4) | 44-39 | |
| » Starters: Gene Wright vs Doc White | Third | 9 out |
| Friday, July 31 |
| » Defeated White Sox (37-45), 5-2 | South Side Park III (2-4) | 45-39 | |
| » Starters: Addie Joss vs Patsy Flaherty | Third | 8½ out |
| Saturday, August 1 |
| » Lost to White Sox (38-45), 5-0 | South Side Park III (2-5) | 45-40 | |
| » Starters: Earl Moore vs Roy Patterson | Third | 9 out |
| Sunday, August 2 |
| » Lost to White Sox (39-45), 2-0 | South Side Park III (2-6) | 45-41 | Lost 2 |
| » Starters: Alex Pearson vs Doc White | Third | 9½ out |
| Monday, August 3 |
| » Defeated Tigers (42-43), 5-4 | League Park I (25-16) | 46-41 | |
| » Starters: Bill Donovan vs Addie Joss | Third | 8½ out |
| Tuesday, August 4 |
| » Lost to Tigers (43-43), 5-2 | League Park I (25-17) | 46-42 | |
| » Starters: George Mullin vs Red Donahue | Third | 9 out |
| Wednesday, August 5 |
| » Defeated Tigers (43-44), 8-2 | League Park I (26-17) | 47-42 | |
| » Starters: Rube Kisinger vs Earl Moore | Third | 9 out |
| Thursday, August 6 |
| » Lost to Tigers (44-44), 7-6 | League Park I (26-18) | 47-43 | |
| » Starters: Bill Donovan vs Alex Pearson | Third | 9 out |
| Friday, August 7 |
| » Lost to Tigers (45-44), 5-3 | League Park I (26-19) | 47-44 | Lost 2 |
| » Starters: Frank Kitson vs Addie Joss | Fourth | 10 out |
| Saturday, August 8 |
| » Indians forfeited to Tigers. | League Park I (26-20) | 47-45 | Lost 3 |
| » Starters: George Mullin vs Red Donahue | Fourth | 11 out |
| Monday, August 10 |
| » Defeated White Sox (42-50), 10-2 | League Park I (27-20) | 48-45 | |
| » Starters: Roy Patterson vs Earl Moore | Fourth | 11 out |
| Tuesday, August 11 |
| » Defeated White Sox (42-51), 4-2 | League Park I (28-20) | 49-45 | Won 2 |
| » Starters: Frank Owen vs Addie Joss | Fourth | 11 out |
| Wednesday, August 12 |
| » Defeated White Sox (42-52), 6-0 | League Park I (29-20) | 50-45 | Won 3 |
| » Starters: Patsy Flaherty vs Red Donahue | Fourth | 10½ out |
| Thursday, August 13 |
| » Defeated Yankees (47-42), 5-2 | League Park I (30-20) | 51-45 | Won 4 |
| » Starters: Jesse Tannehill vs Earl Moore | Third | 9½ out |
| » Defeated Yankees (47-43), 8-2 | League Park I (31-20) | 52-45 | Won 5 |
| » Starters: John Deering vs Addie Joss | Third | 9½ out |
| Friday, August 14 |
| » Defeated Yankees (47-44), 3-0 | League Park I (32-20) | 53-45 | Won 6 |
| » Starters: Jack Chesbro vs Red Donahue | Third | 9½ out |
| Saturday, August 15 |
| » Defeated Yankees (47-45), 6-5 | League Park I (33-20) | 54-45 | Won 7 |
| » Starters: Clark Griffith vs Earl Moore | Third | 9½ out |
| Monday, August 17 |
| » Defeated Red Sox (63-36), 9-3 | League Park I (34-20) | 55-45 | Won 8 |
| » Starters: Bill Dinneen vs Addie Joss | Third | 8½ out |
| Tuesday, August 18 |
| » Lost to Red Sox (64-36), 10-2 | League Park I (34-21) | 55-46 | |
| » Starters: Cy Young vs Red Donahue | Third | 9½ out |
| Wednesday, August 19 |
| » Defeated Senators (32-69), 2-0 | League Park I (35-21) | 56-46 | |
| » Starters: Davey Dunkle vs Earl Moore | Third | 9½ out |
| Thursday, August 20 |
| » Defeated Senators (32-70), 5-1 | League Park I (36-21) | 57-46 | Won 2 |
| » Starters: Al Orth vs Addie Joss | Third | 8½ out |
| Friday, August 21 |
| » Defeated Senators (32-71), 10-0 | League Park I (37-21) | 58-46 | Won 3 |
| » Starters: Highball Wilson vs Red Donahue | Second | 8½ out |
| Saturday, August 22 |
| » Defeated Athletics (59-48), 11-3 | League Park I (38-21) | 59-46 | Won 4 |
| » Starters: Chief Bender vs Earl Moore | Second | 7½ out |
| Monday, August 24 |
| » Defeated Athletics (59-49), 3-0 | League Park I (39-21) | 60-46 | Won 5 |
| » Starters: Eddie Plank vs Addie Joss | Second | 7½ out |
| Tuesday, August 25 |
| » Lost to Athletics (60-49), 9-3 | League Park I (39-22) | 60-47 | |
| » Starters: Weldon Henley vs Red Donahue | Second | 8 out |
| » Major-league debuts: Ed Killian (Indians) |
| Wednesday, August 26 |
| » Defeated Browns (49-57), 12-4 | League Park I (40-22) | 61-47 | |
| » Starters: Barney Pelty vs Earl Moore | Second | 8 out |
| Saturday, August 29 |
| » Lost to Browns (50-57), 4-0 | Sportsman's Park II (1-4) | 61-48 | |
| » Starters: Ed Killian vs Jack Powell | Second | 9½ out |
| Sunday, August 30 |
| » Defeated Browns (50-58), 7-4 | Sportsman's Park II (2-4) | 62-48 | |
| » Starters: Addie Joss vs Ed Siever | Second | 8½ out |
| » Defeated Browns (50-59), 10-1 | Sportsman's Park II (3-4) | 63-48 | Won 2 |
| » Starters: Red Donahue vs Willie Sudhoff | Second | 8½ out |
| Monday, August 31 |
| » Lost to Browns (51-59), 8-3 | Sportsman's Park II (3-5) | 63-49 | |
| » Starters: Earl Moore vs Gene Wright | Second | 9½ out |
| » Lost to Browns (52-59), 6-2 | Sportsman's Park II (3-6) | 63-50 | Lost 2 |
| » Starters: Jesse Stovall vs Jack Powell | Second | 9½ out |
| » Major-league debuts: Jesse Stovall (Indians) |
| Tuesday, September 1 |
| » Defeated Browns (52-60), 4-0 | Sportsman's Park II (4-6) | 64-50 | |
| » Starters: Ed Killian vs Barney Pelty | Second | 9½ out |
| Wednesday, September 2 |
| » Lost to Tigers (56-54), 4-2 | Bennett Park (0-4) | 64-51 | |
| » Starters: Red Donahue vs Bill Donovan | Second | 10 out |
| Thursday, September 3 |
| » Defeated Tigers (56-55), 1-0 | Bennett Park (1-4) | 65-51 | |
| » Starters: Jesse Stovall vs George Mullin | Second | 10 out |
| Friday, September 4 |
| » Lost to Tigers (57-55), 11-3 | Bennett Park (1-5) | 65-52 | |
| » Starters: Bob Rhoads vs Frank Kitson | Second | 10½ out |
| Saturday, September 5 |
| » Lost to White Sox (53-62), 2-1 | South Side Park III (2-7) | 65-53 | Lost 2 |
| » Starters: Ed Killian vs Roy Patterson | Second | 11½ out |
| Sunday, September 6 |
| » Lost to White Sox (54-62), 1-0 | South Side Park III (2-8) | 65-54 | Lost 3 |
| » Starters: Martin Glendon vs Doc White | Second | 12 out |
| Monday, September 7 |
| » Defeated White Sox (54-63), 4-1 | League Park I (41-22) | 66-54 | |
| » Starters: Frank Owen vs Red Donahue | Second | 11 out |
| » Defeated White Sox (54-64), 7-0 | League Park I (42-22) | 67-54 | Won 2 |
| » Starters: Patsy Flaherty vs Ed Killian | Second | 11 out |
| Tuesday, September 8 |
| » Defeated White Sox (54-65), 6-0 | League Park I (43-22) | 68-54 | Won 3 |
| » Starters: Roy Patterson vs Jesse Stovall | Second | 10 out |
| Wednesday, September 9 |
| » Lost to Browns (57-63), 6-0 | League Park I (43-23) | 68-55 | |
| » Starters: Jack Powell vs Red Donahue | Second | 11 out |
| » Defeated Browns (57-64), 2-1 | League Park I (44-23) | 69-55 | |
| » Starters: Gene Wright vs Bob Rhoads | Second | 11 out |
| Friday, September 11 |
| » Lost to Tigers (60-58), 3-0 | League Park I (44-24) | 69-56 | |
| » Starters: George Mullin vs Martin Glendon | Second | 12 out |
| » Defeated Tigers (60-59), 6-0 | League Park I (45-24) | 70-56 | |
| » Starters: John Skopec vs Ed Killian | Second | 12 out |
| » Major-league debuts: Jack Burns (Tigers) |
| Saturday, September 12 |
| » Defeated Tigers (60-60), 3-2 | League Park I (46-24) | 71-56 | Won 2 |
| » Starters: Bill Donovan vs Jesse Stovall | Second | 11½ out |
| » Defeated Tigers (60-61), 4-0 | League Park I (47-24) | 72-56 | Won 3 |
| » Starters: Frank Kitson vs Red Donahue | Second | 11½ out |
| Wednesday, September 16 |
| » Lost to Red Sox (83-43), 14-7 | Huntington Ave Baseball Grounds (4-4) | 72-57 | |
| » Starters: Ed Killian vs Tom Hughes | Second | 12½ out |
| Thursday, September 17 |
| » Lost to Red Sox (84-43), 14-3 | Huntington Ave Baseball Grounds (4-5) | 72-58 | Lost 2 |
| » Starters: Bob Rhoads vs George Winter | Second | 13½ out |
| Friday, September 18 |
| » Lost to Red Sox (85-43), 7-6 | Huntington Ave Baseball Grounds (4-6) | 72-59 | Lost 3 |
| » Starters: Ed Killian vs Bill Dinneen | Second | 14½ out |
| Saturday, September 19 |
| » Lost to Yankees (65-58), 3-1 | Hilltop Park (4-4) | 72-60 | Lost 4 |
| » Starters: Red Donahue vs Jack Chesbro | Second | 15½ out |
| Future Indian Carl Lind is born in New Orleans, LA. |
| Monday, September 21 |
| » Defeated Yankees (65-59), 8-4 | Hilltop Park (5-4) | 73-60 | |
| » Starters: Bob Rhoads vs Clark Griffith | Second | 15½ out |
| Tuesday, September 22 |
| » Defeated Yankees (65-60), 5-4 | Hilltop Park (6-4) | 74-60 | Won 2 |
| » Starters: Jesse Stovall vs Jesse Tannehill | Second | 14½ out |
| Wednesday, September 23 |
| » Lost to Senators (43-89), 7-5 | American League Park II (5-3) | 74-61 | |
| » Starters: Ed Killian vs Happy Townsend | Second | 14 out |
| Thursday, September 24 |
| » Defeated Senators (43-90), 12-2 | American League Park II (6-3) | 75-61 | |
| » Starters: Red Donahue vs Al Orth | Second | 14 out |
| Friday, September 25 |
| » Defeated Senators (43-91), 14-5 | American League Park II (7-3) | 76-61 | Won 2 |
| » Starters: Martin Glendon vs Davey Dunkle | Second | 13½ out |
| Saturday, September 26 |
| » Lost to Athletics (74-59), 4-2 | Columbia Park (3-5) | 76-62 | |
| » Starters: Bob Rhoads vs Weldon Henley | Third | 14 out |
| Sunday, September 27 |
| » Major-league debuts: George Moriarty (Cubs) |
| Monday, September 28 |
| » Lost to Athletics (75-59), 4-3 | Columbia Park (3-6) | 76-63 | Lost 2 |
| » Starters: Red Donahue vs Eddie Plank | Third | 15½ out |
| Tuesday, September 29 |
| » Defeated Athletics (75-60), 7-5 | Columbia Park (4-6) | 77-63 | |
| » Starters: Jesse Stovall vs Ed Pinnance | Third | 15 out |
| Saturday, October 10 |
| Future Indian Fay Thomas is born in Holyrood, KS. |
| Monday, December 14 |
| Future Indian Jim Moore is born in Prescott, AR. |
Game information provided by Retrosheet (www.retrosheet.org) |
