| Tuesday, January 14 |
| Future Red Sox Smead Jolley is born in Wesson, AR. |
| Sunday, March 2 |
| Future Red Sox Moe Berg is born in New York, NY. |
| Thursday, April 17 |
| » Major-league debuts: Homer Smoot (Cardinals) |
| Friday, April 18 |
| » Major-league debuts: Red Dooin (Phillies) |
| Saturday, April 19 |
| » Defeated Orioles (0-1), 7-6 | Huntington Ave Baseball Grounds (1-0) | 1-0 | |
| » Starters: Tom Hughes vs Cy Young | First | -- |
| » Major-league debuts: Patsy Dougherty (Red Sox) |
| Monday, April 21 |
| » Major-league debuts: Jack O'Neill (Cardinals) |
| Wednesday, April 23 |
| » Lost to Senators (1-0), 7-3 | American League Park I (0-1) | 1-1 | |
| » Starters: Bill Dinneen vs Al Orth | Second | ½ out |
| » Major-league debuts: Lew Drill (Senators) |
| Thursday, April 24 |
| » Defeated Senators (1-1), 11-3 | American League Park I (1-1) | 2-1 | |
| » Starters: Cy Young vs Bill Carrick | Second | ½ out |
| Friday, April 25 |
| » Lost to Senators (2-1), 15-4 | American League Park I (1-2) | 2-2 | |
| » Starters: Bert Husting vs Happy Townsend | Third | ½ out |
| Saturday, April 26 |
| » Lost to Senators (3-1), 15-7 | American League Park I (1-3) | 2-3 | Lost 2 |
| » Starters: Bill Dinneen vs Watty Lee | Fourth | 1½ out |
| Monday, April 28 |
| » Defeated Orioles (2-3), 7-3 | Oriole Park IV (1-0) | 3-3 | |
| » Starters: Cy Young vs Joe McGinnity | Fourth | 1½ out |
| Wednesday, April 30 |
| » Lost to Orioles (3-3), 5-4 | Oriole Park IV (1-1) | 3-4 | |
| » Starters: George Winter vs Tom Hughes | Fifth | 1½ out |
| Thursday, May 1 |
| » Defeated Orioles (3-4), 6-4 | Oriole Park IV (2-1) | 4-4 | |
| » Starters: Bill Dinneen vs Harry Howell | Third | 1 out |
| Friday, May 2 |
| » Lost to Orioles (4-4), 14-6 | Huntington Ave Baseball Grounds (1-1) | 4-5 | |
| » Starters: Joe McGinnity vs Cy Young | Fourth | 2 out |
| Saturday, May 3 |
| » Defeated Orioles (4-5), 10-1 | Huntington Ave Baseball Grounds (2-1) | 5-5 | |
| » Starters: Charlie Shields vs Cy Young | Fourth | 2 out |
| Monday, May 5 |
| » Defeated Orioles (4-6), 5-2 | Huntington Ave Baseball Grounds (3-1) | 6-5 | Won 2 |
| » Starters: Tom Hughes vs George Winter | Third | 1 out |
| Tuesday, May 6 |
| » Defeated Orioles (4-7), 5-4 | Huntington Ave Baseball Grounds (4-1) | 7-5 | Won 3 |
| » Starters: Frank Foreman vs Bill Dinneen | Fourth | 1½ out |
| Wednesday, May 7 |
| » Defeated Senators (5-8), 12-8 | Huntington Ave Baseball Grounds (5-1) | 8-5 | Won 4 |
| » Starters: Happy Townsend vs Cy Young | Third | ½ out |
| Thursday, May 8 |
| » Lost to Senators (6-8), 5-1 | Huntington Ave Baseball Grounds (5-2) | 8-6 | |
| » Starters: Casey Patten vs George Winter | Fourth | 1½ out |
| Friday, May 9 |
| » Lost to Senators (7-8), 5-4 | Huntington Ave Baseball Grounds (5-3) | 8-7 | Lost 2 |
| » Starters: Watty Lee vs Bill Dinneen | Fourth | 2 out |
| Saturday, May 10 |
| » Defeated Senators (7-9), 3-1 | Huntington Ave Baseball Grounds (6-3) | 9-7 | |
| » Starters: Al Orth vs Cy Young | Fourth | 1½ out |
| Monday, May 12 |
| » Defeated Athletics (10-6), 8-2 | Columbia Park (1-0) | 10-7 | Won 2 |
| » Starters: George Winter vs Eddie Plank | Third | 1½ out |
| Wednesday, May 14 |
| » Lost to Athletics (11-6), 5-1 | Columbia Park (1-1) | 10-8 | |
| » Starters: Bill Dinneen vs Bert Husting | Third | 1½ out |
| Thursday, May 15 |
| » Defeated Athletics (11-7), 6-3 | Columbia Park (2-1) | 11-8 | |
| » Starters: Cy Young vs Eddie Plank | Third | 1½ out |
| Friday, May 16 |
| » Defeated Athletics (11-8), 4-2 | Huntington Ave Baseball Grounds (7-3) | 12-8 | Won 2 |
| » Starters: Snake Wiltse vs George Winter | Second | 1½ out |
| Saturday, May 17 |
| » Lost to Athletics (12-8), 7-5 | Huntington Ave Baseball Grounds (7-4) | 12-9 | |
| » Starters: Bert Husting vs Bill Dinneen | Fourth | 1½ out |
| Tuesday, May 20 |
| » Defeated Athletics (12-9), 2-1 | Huntington Ave Baseball Grounds (8-4) | 13-9 | |
| » Starters: Eddie Plank vs Cy Young | Second | 1 out |
| Wednesday, May 21 |
| » Lost to White Sox (13-8), 2-1 | Huntington Ave Baseball Grounds (8-5) | 13-10 | |
| » Starters: Wiley Piatt vs George Winter | Third | 1 out |
| Future Red Sox Earl Averill is born in Snohomish, WA. |
| Thursday, May 22 |
| » Lost to White Sox (14-8), 4-3 | Huntington Ave Baseball Grounds (8-6) | 13-11 | Lost 2 |
| » Starters: Roy Patterson vs Bill Dinneen | Fifth | 2 out |
| Friday, May 23 |
| » Defeated White Sox (14-9), 6-3 | Huntington Ave Baseball Grounds (9-6) | 14-11 | |
| » Starters: Clark Griffith vs Cy Young | Fourth | 1 out |
| Saturday, May 24 |
| » Defeated White Sox (14-10), 5-3 | Huntington Ave Baseball Grounds (10-6) | 15-11 | Won 2 |
| » Starters: Wiley Piatt vs George Winter | Second | 1 out |
| Monday, May 26 |
| » Lost to Browns (14-10), 3-0 | Huntington Ave Baseball Grounds (10-7) | 15-12 | |
| » Starters: Jack Powell vs Bill Dinneen | Fifth | 1 out |
| Tuesday, May 27 |
| » Defeated Browns (14-11), 6-2 | Huntington Ave Baseball Grounds (11-7) | 16-12 | |
| » Starters: Bill Reidy vs Cy Young | Second | 1 out |
| Wednesday, May 28 |
| » Defeated Browns (14-12), 6-2 | Huntington Ave Baseball Grounds (12-7) | 17-12 | Won 2 |
| » Starters: Jack Harper vs George Winter | Second | 1 out |
| Thursday, May 29 |
| » Defeated Browns (14-13), 6-2 | Huntington Ave Baseball Grounds (13-7) | 18-12 | Won 3 |
| » Starters: Red Donahue vs Bill Dinneen | Second | 1 out |
| Friday, May 30 |
| » Lost to Tigers (15-13), 10-5 | Huntington Ave Baseball Grounds (13-8) | 18-13 | |
| » Starters: Roscoe Miller vs Pep Deininger | Second | 1 out |
| » Defeated Tigers (15-14), 12-0 | Huntington Ave Baseball Grounds (14-8) | 19-13 | |
| » Starters: Win Mercer vs Cy Young | Second | 1 out |
| Saturday, May 31 |
| » Lost to Tigers (16-14), 13-7 | Huntington Ave Baseball Grounds (14-9) | 19-14 | |
| » Starters: Joe Yeager vs George Winter | Third | 1 out |
| Monday, June 2 |
| » Defeated Tigers (16-15), 4-2 | Huntington Ave Baseball Grounds (15-9) | 20-14 | |
| » Starters: Roscoe Miller vs Bill Dinneen | Second | 1 out |
| Wednesday, June 4 |
| » Lost to Indians (12-24), 4-3 | League Park I (0-1) | 20-15 | |
| » Starters: George Prentiss vs Earl Moore | Second | 1½ out |
| Thursday, June 5 |
| » Defeated Indians (12-25), 3-2 | League Park I (1-1) | 21-15 | |
| » Starters: Cy Young vs Addie Joss | Second | ½ out |
| Friday, June 6 |
| » Lost to Indians (13-25), 14-3 | League Park I (1-2) | 21-16 | |
| » Starters: George Winter vs Gene Wright | Third | 1 out |
| Saturday, June 7 |
| » Lost to Browns (18-17), 4-3 | Sportsman's Park II (0-1) | 21-17 | Lost 2 |
| » Starters: Bill Dinneen vs Jack Powell | Third | 1 out |
| Sunday, June 8 |
| » Defeated Browns (18-18), 7-1 | Sportsman's Park II (1-1) | 22-17 | |
| » Starters: Cy Young vs Jack Harper | Third | 1 out |
| Monday, June 9 |
| » Lost to Browns (19-18), 8-3 | Sportsman's Park II (1-2) | 22-18 | |
| » Starters: George Winter vs Red Donahue | Third | 1½ out |
| Tuesday, June 10 |
| » Defeated Browns (19-19), 5-4 | Sportsman's Park II (2-2) | 23-18 | |
| » Starters: Bill Dinneen vs Jack Harper | Third | 1½ out |
| Wednesday, June 11 |
| » Lost to White Sox (24-15), 3-2 | South Side Park III (0-1) | 23-19 | |
| » Starters: Cy Young vs Clark Griffith | Third | 2½ out |
| Thursday, June 12 |
| » Lost to White Sox (25-15), 5-2 | South Side Park III (0-2) | 23-20 | Lost 2 |
| » Starters: George Winter vs Nixey Callahan | Third | 3½ out |
| Friday, June 13 |
| » Lost to White Sox (26-15), 9-0 | South Side Park III (0-3) | 23-21 | Lost 3 |
| » Starters: Bill Dinneen vs Wiley Piatt | Third | 4½ out |
| Saturday, June 14 |
| » Defeated White Sox (26-16), 2-1 | South Side Park III (1-3) | 24-21 | |
| » Starters: Cy Young vs Roy Patterson | Third | 3½ out |
| Sunday, June 15 |
| » Defeated Indians (18-29), 5-2 | Mahaffey Park (1-0) | 25-21 | Won 2 |
| » Starters: George Winter vs Gene Wright | Third | 3 out |
| Tuesday, June 17 |
| » Lost to Indians (19-29), 7-3 | Huntington Ave Baseball Grounds (15-10) | 25-22 | |
| » Starters: Earl Moore vs Bill Dinneen | Third | 5 out |
| » Lost to Indians (20-29), 4-3 | Huntington Ave Baseball Grounds (15-11) | 25-23 | Lost 2 |
| » Starters: Addie Joss vs Cy Young | Third | 5 out |
| Wednesday, June 18 |
| » Defeated Indians (20-30), 8-3 | Huntington Ave Baseball Grounds (16-11) | 26-23 | |
| » Starters: Oscar Streit vs George Prentiss | Third | 4½ out |
| Thursday, June 19 |
| » Defeated Tigers (23-24), 4-1 | Bennett Park (1-0) | 27-23 | Won 2 |
| » Starters: George Winter vs Ed Siever | Third | 4½ out |
| Friday, June 20 |
| » Lost to Tigers (24-24), 3-0 | Bennett Park (1-1) | 27-24 | |
| » Starters: Bill Dinneen vs Roscoe Miller | Third | 5 out |
| Saturday, June 21 |
| » Defeated Tigers (24-25), 4-1 | Bennett Park (2-1) | 28-24 | |
| » Starters: Cy Young vs Win Mercer | Second | 5 out |
| Sunday, June 22 |
| » Defeated Tigers (24-26), 7-5 | Burns Park (1-0) | 29-24 | Won 2 |
| » Starters: George Prentiss vs George Mullin | Second | 3½ out |
| Tuesday, June 24 |
| » Lost to Senators (25-29), 7-6 | American League Park I (1-4) | 29-25 | |
| » Starters: Cy Young vs Al Orth | Second | 5 out |
| » Major-league debuts: Doc Adkins (Red Sox) |
| Wednesday, June 25 |
| » Lost to Senators (26-29), 4-3 | American League Park I (1-5) | 29-26 | Lost 2 |
| » Starters: Bill Dinneen vs Casey Patten | Second | 5½ out |
| Thursday, June 26 |
| » Defeated Senators (26-30), 4-2 | American League Park I (2-5) | 30-26 | |
| » Starters: Doc Adkins vs Bill Carrick | Second | 4½ out |
| Friday, June 27 |
| » Defeated Orioles (26-30), 6-3 | Oriole Park IV (3-1) | 31-26 | Won 2 |
| » Starters: George Winter vs Harry Howell | Second | 4 out |
| Saturday, June 28 |
| » Defeated Orioles (26-31), 9-4 | Oriole Park IV (4-1) | 32-26 | Won 3 |
| » Starters: Cy Young vs Joe McGinnity | Second | 3½ out |
| Tuesday, July 1 |
| » Defeated Senators (27-32), 9-2 | Huntington Ave Baseball Grounds (17-11) | 33-26 | Won 4 |
| » Starters: Casey Patten vs Bill Dinneen | Second | 3½ out |
| Wednesday, July 2 |
| » Lost to Senators (28-32), 8-3 | Huntington Ave Baseball Grounds (17-12) | 33-27 | |
| » Starters: Al Orth vs Doc Adkins | Second | 3 out |
| » Major-league debuts: Dave Williams (Red Sox) |
| Friday, July 4 |
| » Defeated Orioles (27-33), 5-3 | Huntington Ave Baseball Grounds (18-12) | 34-27 | |
| » Starters: Charlie Shields vs George Winter | Second | 3½ out |
| » Defeated Orioles (27-34), 5-4 | Huntington Ave Baseball Grounds (19-12) | 35-27 | Won 2 |
| » Starters: Jack Cronin vs Cy Young | Second | 3½ out |
| Saturday, July 5 |
| » Lost to Orioles (28-34), 5-4 | Huntington Ave Baseball Grounds (19-13) | 35-28 | |
| » Starters: Joe McGinnity vs Bill Dinneen | Second | 4½ out |
| Monday, July 7 |
| » Defeated Athletics (30-29), 4-2 | Huntington Ave Baseball Grounds (20-13) | 36-28 | |
| » Starters: Eddie Plank vs George Winter | Second | 3 out |
| Tuesday, July 8 |
| » Lost to Athletics (31-29), 22-9 | Huntington Ave Baseball Grounds (20-14) | 36-29 | |
| » Starters: Bert Husting vs George Prentiss | Second | 4 out |
| Wednesday, July 9 |
| » Lost to Athletics (32-29), 4-2 | Huntington Ave Baseball Grounds (20-15) | 36-30 | Lost 2 |
| » Starters: Rube Waddell vs George Winter | Third | 4½ out |
| Thursday, July 10 |
| » Defeated Athletics (32-30), 3-1 | Huntington Ave Baseball Grounds (21-15) | 37-30 | |
| » Starters: Fred Mitchell vs Cy Young | Second | 4 out |
| Friday, July 11 |
| » Defeated Athletics (32-31), 8-2 | Columbia Park (3-1) | 38-30 | Won 2 |
| » Starters: George Winter vs Bert Husting | Second | 4 out |
| Saturday, July 12 |
| » Lost to Athletics (33-31), 3-2 | Columbia Park (3-2) | 38-31 | |
| » Starters: Bill Dinneen vs Rube Waddell | Second | 5 out |
| Monday, July 14 |
| » Lost to Athletics (34-31), 4-3 | Columbia Park (3-3) | 38-32 | Lost 2 |
| » Starters: Cy Young vs Highball Wilson | Second | 5½ out |
| Tuesday, July 15 |
| » Lost to Indians (32-39), 2-0 | Huntington Ave Baseball Grounds (21-16) | 38-33 | Lost 3 |
| » Starters: Addie Joss vs George Winter | Third | 5½ out |
| Wednesday, July 16 |
| » Lost to Indians (33-39), 5-2 | Huntington Ave Baseball Grounds (21-17) | 38-34 | Lost 4 |
| » Starters: Earl Moore vs Bill Dinneen | Third | 6½ out |
| Thursday, July 17 |
| » Lost to Indians (34-39), 3-2 | Huntington Ave Baseball Grounds (21-18) | 38-35 | Lost 5 |
| » Starters: Gene Wright vs Cy Young | Fourth | 6½ out |
| Friday, July 18 |
| » Lost to Indians (35-39), 14-4 | Huntington Ave Baseball Grounds (21-19) | 38-36 | Lost 6 |
| » Starters: Bill Bernhard vs Tom Hughes | Fourth | 6½ out |
| Saturday, July 19 |
| » Defeated White Sox (42-28), 2-0 | Huntington Ave Baseball Grounds (22-19) | 39-36 | |
| » Starters: Ned Garvin vs Cy Young | Fourth | 5½ out |
| Monday, July 21 |
| » Defeated White Sox (42-29), 5-3 | Huntington Ave Baseball Grounds (23-19) | 40-36 | Won 2 |
| » Starters: Roy Patterson vs Bill Dinneen | Third | 4½ out |
| Tuesday, July 22 |
| » Defeated White Sox (42-30), 4-1 | Huntington Ave Baseball Grounds (24-19) | 41-36 | Won 3 |
| » Starters: Wiley Piatt vs Cy Young | Third | 3½ out |
| Wednesday, July 23 |
| » Defeated Browns (40-33), 3-2 | Huntington Ave Baseball Grounds (25-19) | 42-36 | Won 4 |
| » Starters: Red Donahue vs Bill Dinneen | Fourth | 2½ out |
| Thursday, July 24 |
| » Defeated Browns (40-34), 4-3 | Huntington Ave Baseball Grounds (26-19) | 43-36 | Won 5 |
| » Starters: Jack Powell vs Cy Young | Third | 3 out |
| Friday, July 25 |
| » Defeated Browns (40-35), 6-3 | Huntington Ave Baseball Grounds (27-19) | 44-36 | Won 6 |
| » Starters: Jack Harper vs Tully Sparks | Third | 2½ out |
| Saturday, July 26 |
| » Defeated Tigers (31-44), 4-1 | Huntington Ave Baseball Grounds (28-19) | 45-36 | Won 7 |
| » Starters: Ed Siever vs Bill Dinneen | Third | 2½ out |
| Monday, July 28 |
| » Defeated Tigers (31-45), 8-1 | Huntington Ave Baseball Grounds (29-19) | 46-36 | Won 8 |
| » Starters: Joe Yeager vs Cy Young | Second | 2½ out |
| Tuesday, July 29 |
| » Lost to Tigers (32-45), 6-5 | Huntington Ave Baseball Grounds (29-20) | 46-37 | |
| » Starters: Win Mercer vs Tom Hughes | Second | 2½ out |
| Thursday, July 31 |
| » Lost to Indians (38-47), 3-0 | League Park I (1-3) | 46-38 | Lost 2 |
| » Starters: Bill Dinneen vs Bill Bernhard | Third | 2½ out |
| Friday, August 1 |
| » Lost to Indians (39-47), 6-3 | League Park I (1-4) | 46-39 | Lost 3 |
| » Starters: Cy Young vs Addie Joss | Fourth | 2½ out |
| Saturday, August 2 |
| » Defeated Indians (39-48), 2-1 | League Park I (2-4) | 47-39 | |
| » Starters: Tully Sparks vs Earl Moore | Third | 2 out |
| Sunday, August 3 |
| » Lost to Tigers (36-45), 11-9 | Burns Park (1-1) | 47-40 | |
| » Starters: Bill Dinneen vs George Mullin | Fourth | 3 out |
| Future Red Sox Doug Taitt is born in Bay City, MI. |
| Monday, August 4 |
| » Defeated Tigers (36-46), 6-1 | Bennett Park (3-1) | 48-40 | |
| » Starters: Cy Young vs Ed Siever | Third | 3 out |
| Tuesday, August 5 |
| » Lost to Tigers (37-46), 5-2 | Bennett Park (3-2) | 48-41 | |
| » Starters: Tully Sparks vs Win Mercer | Fourth | 3 out |
| Wednesday, August 6 |
| » Defeated Browns (46-38), 7-6 | Sportsman's Park II (3-2) | 49-41 | |
| » Starters: Bill Dinneen vs Jack Powell | Third | 3 out |
| Thursday, August 7 |
| » Lost to Browns (47-38), 12-4 | Sportsman's Park II (3-3) | 49-42 | |
| » Starters: Cy Young vs Red Donahue | Third | 3 out |
| Friday, August 8 |
| » Defeated Browns (47-39), 8-0 | Sportsman's Park II (4-3) | 50-42 | |
| » Starters: Cy Young vs Jack Harper | Third | 2 out |
| Saturday, August 9 |
| » Lost to White Sox (51-38), 8-7 | South Side Park III (1-4) | 50-43 | |
| » Starters: Bill Dinneen vs Wiley Piatt | Third | 3 out |
| Sunday, August 10 |
| » Defeated White Sox (51-39), 5-4 | South Side Park III (2-4) | 51-43 | |
| » Starters: Cy Young vs Roy Patterson | Third | 2 out |
| Monday, August 11 |
| » Lost to White Sox (52-39), 5-4 | South Side Park III (2-5) | 51-44 | |
| » Starters: Tully Sparks vs Clark Griffith | Third | 3 out |
| Wednesday, August 13 |
| » Defeated White Sox (52-40), 9-0 | Huntington Ave Baseball Grounds (30-20) | 52-44 | |
| » Starters: Nixey Callahan vs Bill Dinneen | Fourth | 3 out |
| Thursday, August 14 |
| » Defeated White Sox (52-41), 3-1 | Huntington Ave Baseball Grounds (31-20) | 53-44 | Won 2 |
| » Starters: Wiley Piatt vs Cy Young | Fourth | 3½ out |
| Friday, August 15 |
| » Defeated White Sox (52-42), 2-1 | Huntington Ave Baseball Grounds (32-20) | 54-44 | Won 3 |
| » Starters: Roy Patterson vs Tully Sparks | Fourth | 3 out |
| Saturday, August 16 |
| » Defeated Tigers (39-56), 7-1 | Huntington Ave Baseball Grounds (33-20) | 55-44 | Won 4 |
| » Starters: Win Mercer vs Bill Dinneen | Third | 3 out |
| Monday, August 18 |
| » Tied Tigers, 4-4 | Huntington Ave Baseball Grounds (33-20) | 55-44 | |
| » Starters: George Mullin vs Tom Hughes | Second | 2½ out |
| Wednesday, August 20 |
| » Lost to Indians (50-52), 6-3 | Huntington Ave Baseball Grounds (33-21) | 55-45 | |
| » Starters: Earl Moore vs Tully Sparks | Fourth | 2 out |
| Thursday, August 21 |
| » Defeated Indians (50-53), 4-1 | Huntington Ave Baseball Grounds (34-21) | 56-45 | |
| » Starters: Addie Joss vs Bill Dinneen | Second | 2 out |
| Friday, August 22 |
| » Lost to Indians (51-53), 8-1 | Huntington Ave Baseball Grounds (34-22) | 56-46 | |
| » Starters: Bill Bernhard vs Cy Young | Third | 3 out |
| Saturday, August 23 |
| » Defeated Browns (53-46), 1-0 | Huntington Ave Baseball Grounds (35-22) | 57-46 | |
| » Starters: Jack Powell vs Tully Sparks | Second | 3 out |
| Monday, August 25 |
| » Defeated Browns (53-47), 8-0 | Huntington Ave Baseball Grounds (36-22) | 58-46 | Won 2 |
| » Starters: Red Donahue vs Bill Dinneen | Second | 3 out |
| Tuesday, August 26 |
| » Defeated Browns (53-48), 13-2 | Huntington Ave Baseball Grounds (37-22) | 59-46 | Won 3 |
| » Starters: Jack Powell vs Cy Young | Second | 3 out |
| Thursday, August 28 |
| » Lost to Tigers (41-62), 4-0 | Bennett Park (3-3) | 59-47 | |
| » Starters: Tully Sparks vs Win Mercer | Second | 3 out |
| Friday, August 29 |
| » Defeated Tigers (41-63), 6-1 | Bennett Park (4-3) | 60-47 | |
| » Starters: Bill Dinneen vs George Mullin | Second | 3 out |
| Saturday, August 30 |
| » Defeated Tigers (41-64), 11-1 | Bennett Park (5-3) | 61-47 | Won 2 |
| » Starters: Tom Hughes vs Win Mercer | Second | 2½ out |
| Sunday, August 31 |
| » Defeated Indians (55-57), 3-1 | Jailhouse Flats (1-0) | 62-47 | Won 3 |
| » Starters: Cy Young vs Addie Joss | Second | 1 out |
| Monday, September 1 |
| » Lost to Indians (56-57), 10-0 | League Park I (2-5) | 62-48 | |
| » Starters: Tully Sparks vs Earl Moore | Third | 1 out |
| » Lost to Indians (57-57), 8-0 | League Park I (2-6) | 62-49 | Lost 2 |
| » Starters: Bill Dinneen vs Bill Bernhard | Third | 1 out |
| Tuesday, September 2 |
| » Defeated White Sox (60-51), 9-2 | South Side Park III (3-5) | 63-49 | |
| » Starters: Cy Young vs Nixey Callahan | Second | 1 out |
| Wednesday, September 3 |
| » Major-league debuts: Ed Phelps (Pirates) |
| Thursday, September 4 |
| » Lost to White Sox (61-51), 6-1 | South Side Park III (3-6) | 63-50 | |
| » Starters: Tom Hughes vs Wiley Piatt | Third | 2 out |
| » Defeated White Sox (61-52), 11-1 | South Side Park III (4-6) | 64-50 | |
| » Starters: Bill Dinneen vs Clark Griffith | Third | 2 out |
| » Major-league debuts: Sam McMackin (White Sox) |
| Friday, September 5 |
| » Lost to Browns (64-49), 12-3 | Sportsman's Park II (4-4) | 64-51 | |
| » Starters: Tully Sparks vs Charlie Shields | Third | 2 out |
| Saturday, September 6 |
| » Defeated Browns (64-50), 6-5 | Sportsman's Park II (5-4) | 65-51 | |
| » Starters: Cy Young vs Red Donahue | Third | 2 out |
| Sunday, September 7 |
| » Defeated Browns (64-51), 6-2 | Sportsman's Park II (6-4) | 66-51 | Won 2 |
| » Starters: Bill Dinneen vs Jack Powell | Second | 1½ out |
| Monday, September 8 |
| » Major-league debuts: Jimmy Sebring (Pirates) |
| Tuesday, September 9 |
| » Lost to Senators (54-66), 3-2 | Huntington Ave Baseball Grounds (37-23) | 66-52 | |
| » Starters: Casey Patten vs Cy Young | Third | 2½ out |
| Wednesday, September 10 |
| » Defeated Senators (54-67), 5-3 | Huntington Ave Baseball Grounds (38-23) | 67-52 | |
| » Starters: Al Orth vs Bill Dinneen | Third | 2½ out |
| » Defeated Senators (54-68), 7-5 | Huntington Ave Baseball Grounds (39-23) | 68-52 | Won 2 |
| » Starters: Happy Townsend vs Tully Sparks | Third | 2½ out |
| Thursday, September 11 |
| » Lost to Senators (55-68), 9-7 | Huntington Ave Baseball Grounds (39-24) | 68-53 | |
| » Starters: Bill Carrick vs Tom Hughes | Third | 4 out |
| Friday, September 12 |
| » Defeated Athletics (72-50), 5-4 | Huntington Ave Baseball Grounds (40-24) | 69-53 | |
| » Starters: Rube Waddell vs Cy Young | Second | 3 out |
| Sunday, September 14 |
| » Major-league debuts: Jim Hackett and Art Weaver (Cardinals) |
| Monday, September 15 |
| » Lost to Athletics (73-50), 6-4 | Huntington Ave Baseball Grounds (40-25) | 69-54 | |
| » Starters: Eddie Plank vs Bill Dinneen | Third | 5 out |
| » Lost to Athletics (74-50), 9-2 | Huntington Ave Baseball Grounds (40-26) | 69-55 | Lost 2 |
| » Starters: Rube Waddell vs Cy Young | Third | 5 out |
| Tuesday, September 16 |
| » Defeated Orioles (46-78), 7-2 | Huntington Ave Baseball Grounds (41-26) | 70-55 | |
| » Starters: Jack Katoll vs Tully Sparks | Third | 5 out |
| Wednesday, September 17 |
| » Defeated Orioles (46-79), 13-1 | Huntington Ave Baseball Grounds (42-26) | 71-55 | Won 2 |
| » Starters: Ike Butler vs Tom Hughes | Third | 5½ out |
| » Lost to Orioles (47-79), 5-4 | Huntington Ave Baseball Grounds (42-27) | 71-56 | |
| » Starters: Ernie Ross vs Nick Altrock | Third | 5½ out |
| Thursday, September 18 |
| » Defeated Orioles (47-80), 5-2 | Huntington Ave Baseball Grounds (43-27) | 72-56 | |
| » Starters: Snake Wiltse vs Bill Dinneen | Third | 5½ out |
| Friday, September 19 |
| » Lost to Athletics (78-50), 6-4 | Columbia Park (3-4) | 72-57 | |
| » Starters: Cy Young vs Rube Waddell | Third | 6½ out |
| Saturday, September 20 |
| » Lost to Athletics (79-50), 7-2 | Columbia Park (3-5) | 72-58 | Lost 2 |
| » Starters: Tully Sparks vs Eddie Plank | Fourth | 7½ out |
| Monday, September 22 |
| » Defeated Athletics (79-51), 5-1 | Columbia Park (4-5) | 73-58 | |
| » Starters: Bill Dinneen vs Andy Coakley | Fourth | 7½ out |
| » Lost to Athletics (80-51), 5-3 | Columbia Park (4-6) | 73-59 | |
| » Starters: Nick Altrock vs Rube Waddell | Fourth | 7½ out |
| Tuesday, September 23 |
| » Defeated Senators (58-75), 14-1 | American League Park I (3-5) | 74-59 | |
| » Starters: Bill Dinneen vs Bill Carrick | Fourth | 7½ out |
| Wednesday, September 24 |
| » Lost to Senators (59-75), 8-2 | American League Park I (3-6) | 74-60 | |
| » Starters: Tully Sparks vs Al Orth | Fourth | 9 out |
| Saturday, September 27 |
| » Defeated Orioles (50-85), 9-8 | Oriole Park IV (5-1) | 75-60 | |
| » Starters: Tom Hughes vs Jack Katoll | Third | 7 out |
| » Defeated Orioles (50-86), 4-2 | Oriole Park IV (6-1) | 76-60 | Won 2 |
| » Starters: Bill Dinneen vs Ike Butler | Third | 7 out |
| Monday, September 29 |
| » Defeated Orioles (50-87), 9-5 | Oriole Park IV (7-1) | 77-60 | Won 3 |
| » Starters: Tully Sparks vs Ike Butler | Third | 6½ out |
| Sunday, October 5 |
| » Major-league debuts: Otto Williams (Cardinals) |
| Saturday, October 18 |
| Future Red Sox Charlie Berry is born in Phillipsburg, NJ. |
| Friday, December 12 |
| Future Red Sox Paul Wanninger is born in Birmingham, AL. |
Game information provided by Retrosheet (www.retrosheet.org) |