| Saturday, April 5 |
| Former Athletic Dave Eggler dies in Buffalo, NY at the age of 51. |
| Thursday, April 17 |
| » Major-league debuts: Homer Smoot (Cardinals) |
| Friday, April 18 |
| » Major-league debuts: Red Dooin (Phillies) |
| Saturday, April 19 |
| » Major-league debuts: Patsy Dougherty (Red Sox) |
| Monday, April 21 |
| » Major-league debuts: Jack O'Neill (Cardinals) |
| Wednesday, April 23 |
| » Defeated Orioles (0-2), 8-1 | Oriole Park IV (1-0) | 1-0 | |
| » Starters: Bill Bernhard vs Joe McGinnity | First | -- |
| » Major-league debuts: Luis Castro (Athletics) |
| Thursday, April 24 |
| » Lost to Orioles (1-2), 6-2 | Oriole Park IV (1-1) | 1-1 | |
| » Starters: Eddie Plank vs Tom Hughes | Third | 1 out |
| Saturday, April 26 |
| » Lost to Orioles (2-2), 6-2 | Oriole Park IV (1-2) | 1-2 | Lost 2 |
| » Starters: Bill Duggleby vs Harry Howell | Fifth | 1½ out |
| Monday, April 28 |
| » Defeated Senators (3-2), 12-9 | American League Park I (1-0) | 2-2 | |
| » Starters: Snake Wiltse vs Al Orth | Third | ½ out |
| Tuesday, April 29 |
| » Lost to Senators (4-2), 7-2 | American League Park I (1-1) | 2-3 | |
| » Starters: Eddie Plank vs Casey Patten | Sixth | 1½ out |
| Wednesday, April 30 |
| » Defeated Senators (4-3), 11-7 | American League Park I (2-1) | 3-3 | |
| » Starters: Snake Wiltse vs Happy Townsend | Fourth | 1 out |
| Thursday, May 1 |
| » Defeated Senators (4-4), 6-3 | American League Park I (3-1) | 4-3 | Won 2 |
| » Starters: Bill Duggleby vs Al Orth | Second | ½ out |
| Friday, May 2 |
| » Lost to Senators (5-4), 7-6 | Columbia Park (0-1) | 4-4 | |
| » Starters: Casey Patten vs Eddie Plank | Third | 1½ out |
| Saturday, May 3 |
| » Defeated Senators (5-5), 9-3 | Columbia Park (1-1) | 5-4 | |
| » Starters: Bill Carrick vs Bert Husting | Third | 1½ out |
| Monday, May 5 |
| » Defeated Senators (5-6), 7-5 | Columbia Park (2-1) | 6-4 | Won 2 |
| » Starters: Watty Lee vs Snake Wiltse | Second | ½ out |
| Tuesday, May 6 |
| » Defeated Senators (5-7), 11-0 | Columbia Park (3-1) | 7-4 | Won 3 |
| » Starters: Bill Carrick vs Eddie Plank | Second | 1 out |
| Wednesday, May 7 |
| » Defeated Orioles (4-8), 6-5 | Columbia Park (4-1) | 8-4 | Won 4 |
| » Starters: Joe McGinnity vs Bert Husting | First | -- |
| Thursday, May 8 |
| » Defeated Orioles (4-9), 6-3 | Columbia Park (5-1) | 9-4 | Won 5 |
| » Starters: Harry Howell vs Snake Wiltse | First | -- |
| Friday, May 9 |
| » Lost to Orioles (5-9), 13-6 | Columbia Park (5-2) | 9-5 | |
| » Starters: Tom Hughes vs Ed Kenna | Second | ½ out |
| Saturday, May 10 |
| » Defeated Orioles (5-10), 13-4 | Columbia Park (6-2) | 10-5 | |
| » Starters: Frank Foreman vs Bert Husting | Second | 1 out |
| Monday, May 12 |
| » Lost to Red Sox (10-7), 8-2 | Columbia Park (6-3) | 10-6 | |
| » Starters: George Winter vs Eddie Plank | Second | 1 out |
| Wednesday, May 14 |
| » Defeated Red Sox (10-8), 5-1 | Columbia Park (7-3) | 11-6 | |
| » Starters: Bill Dinneen vs Bert Husting | First | -- |
| Thursday, May 15 |
| » Lost to Red Sox (11-8), 6-3 | Columbia Park (7-4) | 11-7 | |
| » Starters: Cy Young vs Eddie Plank | Second | 1 out |
| Friday, May 16 |
| » Lost to Red Sox (12-8), 4-2 | Huntington Ave Baseball Grounds (0-1) | 11-8 | Lost 2 |
| » Starters: Snake Wiltse vs George Winter | Fourth | 1 out |
| Saturday, May 17 |
| » Defeated Red Sox (12-9), 7-5 | Huntington Ave Baseball Grounds (1-1) | 12-8 | |
| » Starters: Bert Husting vs Bill Dinneen | Second | 1 out |
| Tuesday, May 20 |
| » Lost to Red Sox (13-9), 2-1 | Huntington Ave Baseball Grounds (1-2) | 12-9 | |
| » Starters: Eddie Plank vs Cy Young | Fourth | ½ out |
| Wednesday, May 21 |
| » Defeated Indians (6-18), 12-11 | Columbia Park (8-4) | 13-9 | |
| » Starters: Gene Wright vs Snake Wiltse | Second | ½ out |
| Thursday, May 22 |
| » Lost to Indians (7-18), 11-9 | Columbia Park (8-5) | 13-10 | |
| » Starters: Earl Moore vs Snake Wiltse | Fourth | 1½ out |
| Friday, May 23 |
| » Defeated Indians (7-19), 6-2 | Columbia Park (9-5) | 14-10 | |
| » Starters: Oscar Streit vs Eddie Plank | Third | ½ out |
| Saturday, May 24 |
| » Lost to Indians (8-19), 15-9 | Columbia Park (9-6) | 14-11 | |
| » Starters: Addie Joss vs Bert Husting | Fourth | ½ out |
| Monday, May 26 |
| » Defeated Tigers (14-11), 8-6 | Columbia Park (10-6) | 15-11 | |
| » Starters: Roscoe Miller vs Snake Wiltse | Third | ½ out |
| Wednesday, May 28 |
| » Defeated Tigers (14-12), 11-4 | Columbia Park (11-6) | 16-11 | Won 2 |
| » Starters: Win Mercer vs Eddie Plank | First | -- |
| Thursday, May 29 |
| » Defeated Tigers (14-13), 6-4 | Columbia Park (12-6) | 17-11 | Won 3 |
| » Starters: Joe Yeager vs Snake Wiltse | First | -- |
| Friday, May 30 |
| » Lost to Browns (15-13), 11-7 | Columbia Park (12-7) | 17-12 | |
| » Starters: Willie Sudhoff vs Eddie Plank | First | -- |
| » Defeated Browns (15-14), 11-4 | Columbia Park (13-7) | 18-12 | |
| » Starters: Jack Powell vs Bert Husting | First | -- |
| Saturday, May 31 |
| » Defeated Browns (15-15), 7-6 | Columbia Park (14-7) | 19-12 | Won 2 |
| » Starters: Bill Reidy vs Snake Wiltse | First | -- |
| Monday, June 2 |
| » Defeated Browns (15-16), 5-4 | Columbia Park (15-7) | 20-12 | Won 3 |
| » Starters: Jack Powell vs Bert Husting | First | -- |
| Tuesday, June 3 |
| » Defeated White Sox (18-15), 9-7 | Columbia Park (16-7) | 21-12 | Won 4 |
| » Starters: Nixey Callahan vs Eddie Plank | First | -- |
| Wednesday, June 4 |
| » Lost to White Sox (19-15), 3-0 | Columbia Park (16-8) | 21-13 | |
| » Starters: Roy Patterson vs Snake Wiltse | First | -- |
| Thursday, June 5 |
| » Lost to White Sox (20-15), 11-3 | Columbia Park (16-9) | 21-14 | Lost 2 |
| » Starters: Clark Griffith vs Bert Husting | First | -- |
| Saturday, June 7 |
| » Lost to Tigers (17-18), 9-1 | Bennett Park (0-1) | 21-15 | Lost 3 |
| » Starters: Snake Wiltse vs Ed Siever | First | -- |
| Sunday, June 8 |
| » Defeated Tigers (17-19), 3-2 | Burns Park (1-0) | 22-15 | |
| » Starters: Eddie Plank vs Joe Yeager | First | -- |
| Monday, June 9 |
| » Lost to Tigers (18-19), 10-5 | Bennett Park (0-2) | 22-16 | |
| » Starters: Fred Mitchell vs George Mullin | Second | ½ out |
| Tuesday, June 10 |
| » Lost to Tigers (19-19), 8-4 | Bennett Park (0-3) | 22-17 | Lost 2 |
| » Starters: Snake Wiltse vs Ed Siever | Second | 1½ out |
| Wednesday, June 11 |
| » Defeated Indians (16-27), 4-3 | League Park I (1-0) | 23-17 | |
| » Starters: Eddie Plank vs Gene Wright | Second | 1½ out |
| Thursday, June 12 |
| » Lost to Indians (17-27), 5-4 | League Park I (1-1) | 23-18 | |
| » Starters: Bert Husting vs Earl Moore | Second | 2½ out |
| Friday, June 13 |
| » Defeated Indians (17-28), 6-4 | League Park I (2-1) | 24-18 | |
| » Starters: Fred Mitchell vs Addie Joss | Second | 2½ out |
| Saturday, June 14 |
| » Lost to Indians (18-28), 6-3 | League Park I (2-2) | 24-19 | |
| » Starters: Snake Wiltse vs Bill Bernhard | Second | 2½ out |
| Monday, June 16 |
| » Lost to White Sox (27-16), 10-5 | South Side Park III (0-1) | 24-20 | Lost 2 |
| » Starters: Odie Porter vs Clark Griffith | Second | 3½ out |
| Tuesday, June 17 |
| » Lost to White Sox (28-16), 6-2 | South Side Park III (0-2) | 24-21 | Lost 3 |
| » Starters: Fred Mitchell vs Ned Garvin | Second | 4½ out |
| Thursday, June 19 |
| » Defeated Browns (23-23), 6-3 | Sportsman's Park II (1-0) | 25-21 | |
| » Starters: Bert Husting vs Jack Harper | Second | 4½ out |
| Saturday, June 21 |
| » Lost to Browns (24-23), 5-1 | Sportsman's Park II (1-1) | 25-22 | |
| » Starters: Snake Wiltse vs Red Donahue | Third | 5½ out |
| Sunday, June 22 |
| » Lost to Browns (25-23), 7-4 | Sportsman's Park II (1-2) | 25-23 | Lost 2 |
| » Starters: Fred Mitchell vs Jack Powell | Third | 5 out |
| Tuesday, June 24 |
| » Lost to Orioles (25-28), 6-4 | Oriole Park IV (1-3) | 25-24 | Lost 3 |
| » Starters: Eddie Plank vs Harry Howell | Third | 6½ out |
| Wednesday, June 25 |
| » Defeated Orioles (25-29), 8-6 | Oriole Park IV (2-3) | 26-24 | |
| » Starters: Bert Husting vs Joe McGinnity | Third | 6 out |
| Thursday, June 26 |
| » Lost to Orioles (26-29), 7-3 | Oriole Park IV (2-4) | 26-25 | |
| » Starters: Rube Waddell vs Jack Cronin | Fourth | 6 out |
| Friday, June 27 |
| » Defeated Senators (26-31), 4-2 | American League Park I (4-1) | 27-25 | |
| » Starters: Snake Wiltse vs Happy Townsend | Fourth | 5½ out |
| Saturday, June 28 |
| » Lost to Senators (27-31), 4-3 | American League Park I (4-2) | 27-26 | |
| » Starters: Eddie Plank vs Al Orth | Fourth | 6 out |
| Tuesday, July 1 |
| » Defeated Orioles (26-32), 2-0 | Columbia Park (17-9) | 28-26 | |
| » Starters: Jack Cronin vs Rube Waddell | Third | 6 out |
| Wednesday, July 2 |
| » Lost to Orioles (27-32), 2-1 | Columbia Park (17-10) | 28-27 | |
| » Starters: Joe McGinnity vs Eddie Plank | Fourth | 5½ out |
| Friday, July 4 |
| » Defeated Senators (28-33), 3-1 | Columbia Park (18-10) | 29-27 | |
| » Starters: Bill Carrick vs Fred Mitchell | Third | 6 out |
| » Defeated Senators (28-34), 12-9 | Columbia Park (19-10) | 30-27 | Won 2 |
| » Starters: Casey Patten vs Rube Waddell | Third | 6 out |
| Saturday, July 5 |
| » Lost to Senators (29-34), 9-5 | Columbia Park (19-11) | 30-28 | |
| » Starters: Bill Carrick vs Snake Wiltse | Third | 7 out |
| Monday, July 7 |
| » Lost to Red Sox (36-28), 4-2 | Huntington Ave Baseball Grounds (1-3) | 30-29 | Lost 2 |
| » Starters: Eddie Plank vs George Winter | Fourth | 6½ out |
| Tuesday, July 8 |
| » Defeated Red Sox (36-29), 22-9 | Huntington Ave Baseball Grounds (2-3) | 31-29 | |
| » Starters: Bert Husting vs George Prentiss | Fourth | 6½ out |
| Wednesday, July 9 |
| » Defeated Red Sox (36-30), 4-2 | Huntington Ave Baseball Grounds (3-3) | 32-29 | Won 2 |
| » Starters: Rube Waddell vs George Winter | Fourth | 6 out |
| Thursday, July 10 |
| » Lost to Red Sox (37-30), 3-1 | Huntington Ave Baseball Grounds (3-4) | 32-30 | |
| » Starters: Fred Mitchell vs Cy Young | Fourth | 6½ out |
| Friday, July 11 |
| » Lost to Red Sox (38-30), 8-2 | Columbia Park (19-12) | 32-31 | Lost 2 |
| » Starters: George Winter vs Bert Husting | Fourth | 7½ out |
| Saturday, July 12 |
| » Defeated Red Sox (38-31), 3-2 | Columbia Park (20-12) | 33-31 | |
| » Starters: Bill Dinneen vs Rube Waddell | Fourth | 7½ out |
| Monday, July 14 |
| » Defeated Red Sox (38-32), 4-3 | Columbia Park (21-12) | 34-31 | Won 2 |
| » Starters: Cy Young vs Highball Wilson | Fourth | 7 out |
| Tuesday, July 15 |
| » Defeated White Sox (41-25), 9-3 | Columbia Park (22-12) | 35-31 | Won 3 |
| » Starters: Clark Griffith vs Rube Waddell | Fourth | 6 out |
| Wednesday, July 16 |
| » Lost to White Sox (42-25), 9-4 | Columbia Park (22-13) | 35-32 | |
| » Starters: Roy Patterson vs Eddie Plank | Fourth | 7 out |
| Thursday, July 17 |
| » Defeated White Sox (42-26), 7-4 | Columbia Park (23-13) | 36-32 | |
| » Starters: Wiley Piatt vs Bert Husting | Third | 6 out |
| Friday, July 18 |
| » Defeated White Sox (42-27), 7-6 | Columbia Park (24-13) | 37-32 | Won 2 |
| » Starters: Nixey Callahan vs Rube Waddell | Third | 5 out |
| Saturday, July 19 |
| » Defeated Indians (35-40), 9-3 | Columbia Park (25-13) | 38-32 | Won 3 |
| » Starters: Addie Joss vs Highball Wilson | Third | 4 out |
| Monday, July 21 |
| » Defeated Indians (35-41), 11-10 | Columbia Park (26-13) | 39-32 | Won 4 |
| » Starters: Earl Moore vs Bert Husting | Second | 3 out |
| Tuesday, July 22 |
| » Defeated Indians (35-42), 9-4 | Columbia Park (27-13) | 40-32 | Won 5 |
| » Starters: Addie Joss vs Bert Husting | Second | 2 out |
| Wednesday, July 23 |
| » Defeated Tigers (31-43), 5-2 | Columbia Park (28-13) | 41-32 | Won 6 |
| » Starters: Win Mercer vs Eddie Plank | Second | 1 out |
| Saturday, July 26 |
| » Defeated Browns (40-36), 3-1 | Columbia Park (29-13) | 42-32 | Won 7 |
| » Starters: Willie Sudhoff vs Rube Waddell | Second | 1 out |
| Monday, July 28 |
| » Lost to Browns (41-36), 9-4 | Columbia Park (29-14) | 42-33 | |
| » Starters: Jack Powell vs Highball Wilson | Third | 1 out |
| Tuesday, July 29 |
| » Lost to Browns (42-36), 3-1 | Columbia Park (29-15) | 42-34 | Lost 2 |
| » Starters: Jack Harper vs Rube Waddell | Third | 1 out |
| Thursday, July 31 |
| » Tied Browns, 4-4 | Sportsman's Park II (1-2) | 42-34 | |
| » Starters: Rube Waddell vs Red Donahue | Second | 1½ out |
| Friday, August 1 |
| » Lost to Browns (43-36), 11-5 | Sportsman's Park II (1-3) | 42-35 | Lost 3 |
| » Starters: Highball Wilson vs Jack Powell | Second | 1½ out |
| Saturday, August 2 |
| » Defeated Browns (43-37), 4-1 | Sportsman's Park II (2-3) | 43-35 | |
| » Starters: Eddie Plank vs Willie Sudhoff | Second | 2 out |
| Sunday, August 3 |
| » Lost to White Sox (48-35), 3-1 | South Side Park III (0-3) | 43-36 | |
| » Starters: Rube Waddell vs Roy Patterson | Second | 3 out |
| Monday, August 4 |
| » Lost to White Sox (49-35), 8-7 | South Side Park III (0-4) | 43-37 | Lost 2 |
| » Starters: Fred Mitchell vs Wiley Piatt | Fourth | 4 out |
| Tuesday, August 5 |
| » Defeated White Sox (49-36), 4-3 | South Side Park III (1-4) | 44-37 | |
| » Starters: Eddie Plank vs Nixey Callahan | Third | 3 out |
| Wednesday, August 6 |
| » Lost to Indians (42-49), 5-4 | League Park I (2-3) | 44-38 | |
| » Starters: Rube Waddell vs Charlie Smith | Fourth | 4 out |
| » Major-league debuts: Charlie Smith (Indians) |
| Friday, August 8 |
| » Lost to Indians (43-49), 5-4 | League Park I (2-4) | 44-39 | Lost 2 |
| » Starters: Fred Mitchell vs Earl Moore | Fourth | 3½ out |
| Saturday, August 9 |
| » Lost to Tigers (39-47), 4-3 | Bennett Park (0-4) | 44-40 | Lost 3 |
| » Starters: Eddie Plank vs Win Mercer | Fourth | 4½ out |
| Sunday, August 10 |
| » Defeated Tigers (39-48), 9-1 | Burns Park (2-0) | 45-40 | |
| » Starters: Bert Husting vs George Mullin | Fourth | 3½ out |
| Monday, August 11 |
| » Defeated Tigers (39-49), 1-0 | Bennett Park (1-4) | 46-40 | Won 2 |
| » Starters: Rube Waddell vs Ed Siever | Fourth | 3½ out |
| Wednesday, August 13 |
| » Defeated Tigers (39-50), 8-0 | Columbia Park (30-15) | 47-40 | Won 3 |
| » Starters: Win Mercer vs Rube Waddell | Third | 2 out |
| » Defeated Tigers (39-51), 9-0 | Columbia Park (31-15) | 48-40 | Won 4 |
| » Starters: George Mullin vs Bert Husting | Third | 2 out |
| Thursday, August 14 |
| » Defeated Tigers (39-52), 4-3 | Columbia Park (32-15) | 49-40 | Won 5 |
| » Starters: Arch McCarthy vs Highball Wilson | Third | 1 out |
| » Defeated Tigers (39-53), 5-1 | Columbia Park (33-15) | 50-40 | Won 6 |
| » Starters: Joe Yeager vs Fred Mitchell | Third | 1 out |
| Friday, August 15 |
| » Defeated Tigers (39-54), 11-4 | Columbia Park (34-15) | 51-40 | Won 7 |
| » Starters: George Mullin vs Bert Husting | First | -- |
| » Defeated Tigers (39-55), 5-2 | Columbia Park (35-15) | 52-40 | Won 8 |
| » Starters: Arch McCarthy vs Eddie Plank | First | -- |
| Saturday, August 16 |
| » Defeated White Sox (52-43), 2-1 | Columbia Park (36-15) | 53-40 | Won 9 |
| » Starters: Clark Griffith vs Rube Waddell | First | -- |
| Monday, August 18 |
| » Defeated White Sox (52-44), 12-5 | Columbia Park (37-15) | 54-40 | Won 10 |
| » Starters: Roy Patterson vs Eddie Plank | First | -- |
| Tuesday, August 19 |
| » Lost to White Sox (53-44), 5-2 | Columbia Park (37-16) | 54-41 | |
| » Starters: Clark Griffith vs Rube Waddell | First | -- |
| Wednesday, August 20 |
| » Defeated Browns (53-43), 4-1 | Columbia Park (38-16) | 55-41 | |
| » Starters: Jack Powell vs Bert Husting | First | -- |
| Thursday, August 21 |
| » Defeated Browns (53-44), 12-5 | Columbia Park (39-16) | 56-41 | Won 2 |
| » Starters: Jack Harper vs Eddie Plank | First | -- |
| Friday, August 22 |
| » Defeated Browns (53-45), 12-4 | Columbia Park (40-16) | 57-41 | Won 3 |
| » Starters: Harry Kane vs Fred Mitchell | First | -- |
| Saturday, August 23 |
| » Defeated Indians (51-54), 12-1 | Columbia Park (41-16) | 58-41 | Won 4 |
| » Starters: Earl Moore vs Highball Wilson | First | -- |
| Monday, August 25 |
| » Defeated Indians (51-55), 7-3 | Columbia Park (42-16) | 59-41 | Won 5 |
| » Starters: Addie Joss vs Fred Mitchell | First | -- |
| Tuesday, August 26 |
| » Defeated Indians (51-56), 13-2 | Columbia Park (43-16) | 60-41 | Won 6 |
| » Starters: Otto Hess vs Eddie Plank | First | -- |
| Wednesday, August 27 |
| » Lost to Indians (52-56), 2-1 | League Park I (2-5) | 60-42 | |
| » Starters: Highball Wilson vs Bill Bernhard | First | -- |
| Thursday, August 28 |
| » Lost to White Sox (57-47), 4-1 | South Side Park III (1-5) | 60-43 | Lost 2 |
| » Starters: Bert Husting vs Roy Patterson | First | -- |
| » Defeated White Sox (57-48), 5-4 | South Side Park III (2-5) | 61-43 | |
| » Starters: Rube Waddell vs Wiley Piatt | First | -- |
| Friday, August 29 |
| » Defeated White Sox (57-49), 10-6 | South Side Park III (3-5) | 62-43 | Won 2 |
| » Starters: Eddie Plank vs Nixey Callahan | First | -- |
| » Major-league debuts: Ed Hughes (White Sox) |
| Saturday, August 30 |
| » Lost to White Sox (58-49), 4-2 | South Side Park III (3-6) | 62-44 | |
| » Starters: Fred Mitchell vs Clark Griffith | First | -- |
| » Defeated White Sox (58-50), 6-5 | South Side Park III (4-6) | 63-44 | |
| » Starters: Rube Waddell vs Roy Patterson | First | -- |
| Sunday, August 31 |
| » Lost to Browns (58-48), 1-0 | Sportsman's Park II (2-4) | 63-45 | |
| » Starters: Eddie Plank vs Red Donahue | First | -- |
| » Lost to Browns (59-48), 3-2 | Sportsman's Park II (2-5) | 63-46 | Lost 2 |
| » Starters: Bert Husting vs Jack Powell | First | -- |
| Monday, September 1 |
| » Lost to Browns (60-48), 5-1 | Sportsman's Park II (2-6) | 63-47 | Lost 3 |
| » Starters: Rube Waddell vs Willie Sudhoff | First | -- |
| » Lost to Browns (61-48), 4-3 | Sportsman's Park II (2-7) | 63-48 | Lost 4 |
| » Starters: Fred Mitchell vs Jack Powell | First | -- |
| Tuesday, September 2 |
| » Defeated Tigers (43-66), 5-1 | Bennett Park (2-4) | 64-48 | |
| » Starters: Rube Waddell vs Joe Yeager | First | -- |
| Wednesday, September 3 |
| » Defeated Tigers (43-67), 5-3 | Bennett Park (3-4) | 65-48 | Won 2 |
| » Starters: Bert Husting vs Wish Egan | First | -- |
| » Major-league debuts: Wish Egan (Tigers) |
| Thursday, September 4 |
| » Defeated Tigers (43-68), 13-4 | Bennett Park (4-4) | 66-48 | Won 3 |
| » Starters: Rube Waddell vs Arch McCarthy | First | -- |
| Friday, September 5 |
| » Lost to Indians (61-57), 10-7 | League Park I (2-6) | 66-49 | |
| » Starters: Highball Wilson vs Bill Bernhard | First | -- |
| Saturday, September 6 |
| » Defeated Indians (61-58), 3-2 | League Park I (3-6) | 67-49 | |
| » Starters: Rube Waddell vs Addie Joss | First | -- |
| Monday, September 8 |
| » Defeated Indians (61-59), 8-5 | League Park I (4-6) | 68-49 | Won 2 |
| » Starters: Rube Waddell vs Earl Moore | First | -- |
| Wednesday, September 10 |
| » Defeated Orioles (46-72), 9-5 | Columbia Park (44-16) | 69-49 | Won 3 |
| » Starters: Ike Butler vs Fred Mitchell | First | -- |
| » Defeated Orioles (46-73), 5-4 | Columbia Park (45-16) | 70-49 | Won 4 |
| » Starters: Jack Katoll vs Bert Husting | First | -- |
| Thursday, September 11 |
| » Defeated Orioles (46-74), 9-1 | Columbia Park (46-16) | 71-49 | Won 5 |
| » Starters: Snake Wiltse vs Eddie Plank | First | -- |
| » Defeated Orioles (46-75), 4-3 | Columbia Park (47-16) | 72-49 | Won 6 |
| » Starters: Ike Butler vs Highball Wilson | First | -- |
| Friday, September 12 |
| » Lost to Red Sox (69-53), 5-4 | Huntington Ave Baseball Grounds (3-5) | 72-50 | |
| » Starters: Rube Waddell vs Cy Young | First | -- |
| Sunday, September 14 |
| » Major-league debuts: Jim Hackett and Art Weaver (Cardinals) |
| Monday, September 15 |
| » Defeated Red Sox (69-54), 6-4 | Huntington Ave Baseball Grounds (4-5) | 73-50 | |
| » Starters: Eddie Plank vs Bill Dinneen | First | -- |
| » Defeated Red Sox (69-55), 9-2 | Huntington Ave Baseball Grounds (5-5) | 74-50 | Won 2 |
| » Starters: Rube Waddell vs Cy Young | First | -- |
| Tuesday, September 16 |
| » Defeated Senators (57-69), 7-5 | Columbia Park (48-16) | 75-50 | Won 3 |
| » Starters: Casey Patten vs Bert Husting | First | -- |
| Wednesday, September 17 |
| » Defeated Senators (57-70), 6-5 | Columbia Park (49-16) | 76-50 | Won 4 |
| » Starters: Bill Carrick vs Andy Coakley | First | -- |
| Thursday, September 18 |
| » Defeated Senators (57-71), 6-2 | Columbia Park (50-16) | 77-50 | Won 5 |
| » Starters: Cy Vorhees vs Bert Husting | First | -- |
| Friday, September 19 |
| » Defeated Red Sox (72-57), 6-4 | Columbia Park (51-16) | 78-50 | Won 6 |
| » Starters: Cy Young vs Rube Waddell | First | -- |
| Saturday, September 20 |
| » Defeated Red Sox (72-58), 7-2 | Columbia Park (52-16) | 79-50 | Won 7 |
| » Starters: Tully Sparks vs Eddie Plank | First | -- |
| Monday, September 22 |
| » Lost to Red Sox (73-58), 5-1 | Columbia Park (52-17) | 79-51 | |
| » Starters: Bill Dinneen vs Andy Coakley | First | -- |
| » Defeated Red Sox (73-59), 5-3 | Columbia Park (53-17) | 80-51 | |
| » Starters: Nick Altrock vs Rube Waddell | First | -- |
| Tuesday, September 23 |
| » Defeated Orioles (50-82), 4-3 | Columbia Park (54-17) | 81-51 | Won 2 |
| » Starters: Jack Katoll vs Eddie Plank | First | -- |
| Wednesday, September 24 |
| » Defeated Orioles (50-83), 7-5 | Columbia Park (55-17) | 82-51 | Won 3 |
| » Starters: Ike Butler vs Andy Coakley | First | -- |
| » Defeated Orioles (50-84), 5-4 | Columbia Park (56-17) | 83-51 | Won 4 |
| » Starters: Snake Wiltse vs Highball Wilson | First | -- |
| Saturday, September 27 |
| » Lost to Senators (60-75), 9-4 | American League Park I (4-3) | 83-52 | |
| » Starters: Tad Quinn vs Happy Townsend | First | -- |
| » Lost to Senators (61-75), 7-5 | American League Park I (4-4) | 83-53 | Lost 2 |
| » Starters: Tom Walker vs Casey Patten | First | -- |
| » Major-league debuts: Tad Quinn (Athletics) |
| Sunday, October 5 |
| » Major-league debuts: Otto Williams (Cardinals) |
| Monday, October 27 |
| Future Athletic Jim Keesey is born in Perryville, MD. |
Game information provided by Retrosheet (www.retrosheet.org) |
