| Saturday, January 5 |
| Future White Sox Luke Sewell is born in Titus, AL. |
| Wednesday, February 6 |
| Future White Sox Glenn Wright is born in Archie, MO. |
| Thursday, April 18 |
| » Major-league debuts: Lefty Davis (Dodgers) |
| Friday, April 19 |
| » Major-league debuts: Jim Delahanty (Cubs) |
| Future White Sox Bernie DeViveiros is born in Oakland, CA. |
| Saturday, April 20 |
| » Major-league debuts: John Dobbs (Reds) |
| Monday, April 22 |
| » Major-league debuts: Doc White (Phillies) |
| Wednesday, April 24 |
| » Defeated Indians (0-1), 8-2 | South Side Park III (1-0) | 1-0 | |
| » Starters: Bill Hoffer vs Roy Patterson | First | -- |
| » Major-league debuts: Dave Brain (White Sox) |
| Thursday, April 25 |
| » Defeated Indians (0-2), 7-3 | South Side Park III (2-0) | 2-0 | Won 2 |
| » Starters: Earl Moore vs John Skopec | First | -- |
| Saturday, April 27 |
| » Lost to Indians (1-2), 10-4 | South Side Park III (2-1) | 2-1 | |
| » Starters: Bill Hart vs Jack Katoll | Third | 1 out |
| Sunday, April 28 |
| » Defeated Indians (1-3), 13-1 | South Side Park III (3-1) | 3-1 | |
| » Starters: Bock Baker vs Clark Griffith | Third | 1 out |
| Monday, April 29 |
| » Lost to Tigers (5-0), 3-2 | South Side Park III (3-2) | 3-2 | |
| » Starters: Frank Owen vs Roy Patterson | Fourth | 2 out |
| Tuesday, April 30 |
| » Defeated Tigers (5-1), 4-2 | South Side Park III (4-2) | 4-2 | |
| » Starters: Jack Cronin vs John Skopec | Third | 1 out |
| Wednesday, May 1 |
| » Defeated Tigers (5-2), 19-9 | South Side Park III (5-2) | 5-2 | Won 2 |
| » Starters: Joe Yeager vs Zaza Harvey | Second | 1 out |
| Thursday, May 2 |
| » White Sox forfeited to Tigers. | South Side Park III (5-3) | 5-3 | |
| » Starters: Emil Frisk vs Clark Griffith | Third | 1 out |
| Friday, May 3 |
| » Defeated Brewers (2-7), 11-3 | Lloyd Street Grounds (1-0) | 6-3 | |
| » Starters: John Skopec vs Pink Hawley | Third | 1 out |
| » Major-league debuts: Bill Friel (Brewers) |
| Saturday, May 4 |
| » Defeated Brewers (2-8), 11-3 | Lloyd Street Grounds (2-0) | 7-3 | Won 2 |
| » Starters: Jack Katoll vs Pete Dowling | First | -- |
| Sunday, May 5 |
| » Lost to Brewers (3-8), 21-7 | Lloyd Street Grounds (2-1) | 7-4 | |
| » Starters: Roy Patterson vs Bert Husting | Second | 1 out |
| Monday, May 6 |
| » Defeated Brewers (3-9), 6-3 | Lloyd Street Grounds (3-1) | 8-4 | |
| » Starters: Clark Griffith vs Pink Hawley | Second | 1 out |
| Wednesday, May 8 |
| » Defeated Indians (4-9), 3-1 | League Park I (1-0) | 9-4 | Won 2 |
| » Starters: John Skopec vs Bill Hoffer | Second | 1 out |
| Thursday, May 9 |
| » Defeated Indians (4-10), 4-2 | League Park I (2-0) | 10-4 | Won 3 |
| » Starters: Jack Katoll vs Earl Moore | First | -- |
| Friday, May 10 |
| » Defeated Indians (4-11), 5-4 | League Park I (3-0) | 11-4 | Won 4 |
| » Starters: Roy Patterson vs Bill Hart | First | -- |
| Future White Sox Ted Blankenship is born in Bonham, TX. |
| Saturday, May 11 |
| » Lost to Tigers (12-4), 9-4 | Bennett Park (0-1) | 11-5 | |
| » Starters: John Skopec vs Joe Yeager | Second | 1 out |
| Sunday, May 12 |
| » Lost to Tigers (13-4), 7-5 | Burns Park (0-1) | 11-6 | Lost 2 |
| » Starters: Jack Katoll vs Ed Siever | Second | 2 out |
| Monday, May 13 |
| » Lost to Tigers (14-4), 8-7 | Bennett Park (0-2) | 11-7 | Lost 3 |
| » Starters: Zaza Harvey vs Roscoe Miller | Third | 3 out |
| Tuesday, May 14 |
| » Defeated Tigers (14-5), 6-2 | Bennett Park (1-2) | 12-7 | |
| » Starters: Clark Griffith vs Ed Siever | Third | 2 out |
| Thursday, May 16 |
| » Defeated Brewers (8-12), 14-1 | South Side Park III (6-3) | 13-7 | Won 2 |
| » Starters: Ned Garvin vs John Skopec | Third | 2 out |
| Friday, May 17 |
| » Defeated Brewers (8-13), 7-6 | South Side Park III (7-3) | 14-7 | Won 3 |
| » Starters: Tully Sparks vs Roy Patterson | Second | 2 out |
| Saturday, May 18 |
| » Defeated Brewers (8-14), 5-3 | South Side Park III (8-3) | 15-7 | Won 4 |
| » Starters: Pink Hawley vs Jack Katoll | Second | 1 out |
| Sunday, May 19 |
| » Defeated Brewers (8-15), 14-3 | South Side Park III (9-3) | 16-7 | Won 5 |
| » Starters: Pete Dowling vs Clark Griffith | First | -- |
| Wednesday, May 22 |
| » Lost to Athletics (7-14), 9-5 | South Side Park III (9-4) | 16-8 | |
| » Starters: Wiley Piatt vs John Skopec | Second | ½ out |
| Thursday, May 23 |
| » Defeated Athletics (7-15), 11-9 | South Side Park III (10-4) | 17-8 | |
| » Starters: Eddie Plank vs Jack Katoll | First | -- |
| Saturday, May 25 |
| » Defeated Athletics (7-16), 6-5 | South Side Park III (11-4) | 18-8 | Won 2 |
| » Starters: Wiley Piatt vs Jack Katoll | First | -- |
| Sunday, May 26 |
| » Defeated Orioles (11-8), 5-0 | South Side Park III (12-4) | 19-8 | Won 3 |
| » Starters: Joe McGinnity vs Clark Griffith | First | -- |
| Monday, May 27 |
| » Defeated Orioles (11-9), 10-3 | South Side Park III (13-4) | 20-8 | Won 4 |
| » Starters: Jack Dunn vs Roy Patterson | First | -- |
| Tuesday, May 28 |
| » Lost to Orioles (12-9), 14-5 | South Side Park III (13-5) | 20-9 | |
| » Starters: Joe McGinnity vs John Skopec | First | -- |
| Wednesday, May 29 |
| » Defeated Orioles (12-10), 7-4 | South Side Park III (14-5) | 21-9 | |
| » Starters: Harry Howell vs Jack Katoll | First | -- |
| Thursday, May 30 |
| » Defeated Red Sox (11-12), 8-3 | South Side Park III (15-5) | 22-9 | Won 2 |
| » Starters: Ben Beville vs Clark Griffith | First | -- |
| » Defeated Red Sox (11-13), 5-3 | South Side Park III (16-5) | 23-9 | Won 3 |
| » Starters: Cy Young vs Roy Patterson | First | -- |
| Friday, May 31 |
| » Defeated Red Sox (11-14), 10-5 | South Side Park III (17-5) | 24-9 | Won 4 |
| » Starters: Ted Lewis vs John Skopec | First | -- |
| Saturday, June 1 |
| » Lost to Red Sox (12-14), 10-5 | South Side Park III (17-6) | 24-10 | |
| » Starters: Fred Mitchell vs Zaza Harvey | First | -- |
| Sunday, June 2 |
| » Lost to Senators (16-11), 7-5 | South Side Park III (17-7) | 24-11 | Lost 2 |
| » Starters: Watty Lee vs Clark Griffith | First | -- |
| Monday, June 3 |
| » Lost to Senators (17-11), 5-3 | South Side Park III (17-8) | 24-12 | Lost 3 |
| » Starters: Casey Patten vs Roy Patterson | First | -- |
| Tuesday, June 4 |
| » Defeated Senators (17-12), 3-2 | South Side Park III (18-8) | 25-12 | |
| » Starters: Dale Gear vs Jack Katoll | First | -- |
| Friday, June 7 |
| » Defeated Senators (17-13), 15-4 | American League Park I (1-0) | 26-12 | Won 2 |
| » Starters: Clark Griffith vs Bill Carrick | First | -- |
| Saturday, June 8 |
| » Lost to Senators (18-13), 8-3 | American League Park I (1-1) | 26-13 | |
| » Starters: Roy Patterson vs Watty Lee | First | -- |
| Monday, June 10 |
| » Defeated Senators (18-14), 13-10 | American League Park I (2-1) | 27-13 | |
| » Starters: Jack Katoll vs Casey Patten | First | -- |
| Tuesday, June 11 |
| » Lost to Senators (19-14), 3-1 | American League Park I (2-2) | 27-14 | |
| » Starters: Zaza Harvey vs Watty Lee | First | -- |
| Wednesday, June 12 |
| » Lost to Orioles (17-16), 8-1 | Oriole Park IV (0-1) | 27-15 | Lost 2 |
| » Starters: Clark Griffith vs Frank Foreman | First | -- |
| Thursday, June 13 |
| » Defeated Orioles (17-17), 12-0 | Oriole Park IV (1-1) | 28-15 | |
| » Starters: Roy Patterson vs Joe McGinnity | First | -- |
| Friday, June 14 |
| » Defeated Orioles (17-18), 10-5 | Oriole Park IV (2-1) | 29-15 | Won 2 |
| » Starters: Nixey Callahan vs Harry Howell | First | -- |
| Monday, June 17 |
| » Lost to Red Sox (22-17), 11-1 | Huntington Ave Baseball Grounds (0-1) | 29-16 | |
| » Starters: Jack Katoll vs Fred Mitchell | First | -- |
| » Lost to Red Sox (23-17), 10-4 | Huntington Ave Baseball Grounds (0-2) | 29-17 | Lost 2 |
| » Starters: Roy Patterson vs Cy Young | First | -- |
| Tuesday, June 18 |
| » Lost to Red Sox (24-17), 4-3 | Huntington Ave Baseball Grounds (0-3) | 29-18 | Lost 3 |
| » Starters: Clark Griffith vs Ted Lewis | First | -- |
| Wednesday, June 19 |
| » Lost to Red Sox (25-17), 5-3 | Huntington Ave Baseball Grounds (0-4) | 29-19 | Lost 4 |
| » Starters: Nixey Callahan vs George Winter | First | -- |
| Thursday, June 20 |
| » Lost to Red Sox (26-17), 4-3 | Huntington Ave Baseball Grounds (0-5) | 29-20 | Lost 5 |
| » Starters: Zaza Harvey vs Cy Young | Second | 3 out |
| Friday, June 21 |
| » Defeated Athletics (21-25), 4-0 | Columbia Park (1-0) | 30-20 | |
| » Starters: Clark Griffith vs Wiley Piatt | Second | 3 out |
| Saturday, June 22 |
| » Defeated Athletics (21-26), 6-4 | Columbia Park (2-0) | 31-20 | Won 2 |
| » Starters: Roy Patterson vs Eddie Plank | Second | 3 out |
| Monday, June 24 |
| » Defeated Athletics (21-27), 7-5 | Columbia Park (3-0) | 32-20 | Won 3 |
| » Starters: Nixey Callahan vs Chick Fraser | First | -- |
| Tuesday, June 25 |
| » Defeated Athletics (21-28), 5-0 | Columbia Park (4-0) | 33-20 | Won 4 |
| » Starters: Clark Griffith vs Wiley Piatt | First | -- |
| Thursday, June 27 |
| » Defeated Indians (18-32), 5-1 | South Side Park III (19-8) | 34-20 | Won 5 |
| » Starters: Bill Hoffer vs Jack Katoll | First | -- |
| Friday, June 28 |
| » Defeated Indians (18-33), 7-6 | South Side Park III (20-8) | 35-20 | Won 6 |
| » Starters: Bill Hart vs Roy Patterson | First | -- |
| Saturday, June 29 |
| » Defeated Indians (18-34), 4-1 | South Side Park III (21-8) | 36-20 | Won 7 |
| » Starters: Earl Moore vs Zaza Harvey | First | -- |
| Sunday, June 30 |
| » Defeated Tigers (29-26), 4-2 | South Side Park III (22-8) | 37-20 | Won 8 |
| » Starters: Jack Cronin vs Nixey Callahan | First | -- |
| Tuesday, July 2 |
| » Defeated Tigers (29-27), 3-2 | South Side Park III (23-8) | 38-20 | Won 9 |
| » Starters: Ed Siever vs Clark Griffith | First | -- |
| Wednesday, July 3 |
| » Defeated Indians (21-35), 4-3 | League Park I (4-0) | 39-20 | Won 10 |
| » Starters: Jack Katoll vs Pete Dowling | First | -- |
| Thursday, July 4 |
| » Lost to Indians (22-35), 8-2 | League Park I (4-1) | 39-21 | |
| » Starters: Roy Patterson vs Bill Hart | First | -- |
| » Lost to Indians (23-35), 6-5 | League Park I (4-2) | 39-22 | Lost 2 |
| » Starters: Zaza Harvey vs Bill Hoffer | First | -- |
| Friday, July 5 |
| » Defeated Tigers (31-29), 8-4 | Bennett Park (2-2) | 40-22 | |
| » Starters: Clark Griffith vs Ed Siever | First | -- |
| Saturday, July 6 |
| » Lost to Tigers (32-29), 6-5 | Bennett Park (2-3) | 40-23 | |
| » Starters: Jack Katoll vs Roscoe Miller | Second | 3 out |
| Sunday, July 7 |
| » Lost to Tigers (33-29), 8-3 | Burns Park (0-2) | 40-24 | Lost 2 |
| » Starters: Roy Patterson vs Jack Cronin | Second | 3½ out |
| Tuesday, July 9 |
| » Defeated Brewers (22-42), 17-9 | Lloyd Street Grounds (4-1) | 41-24 | |
| » Starters: Clark Griffith vs Ned Garvin | Second | 3½ out |
| Wednesday, July 10 |
| » Defeated Brewers (22-43), 5-4 | Lloyd Street Grounds (5-1) | 42-24 | Won 2 |
| » Starters: Nixey Callahan vs Tully Sparks | Second | 3½ out |
| Thursday, July 11 |
| » Defeated Brewers (22-44), 5-1 | Lloyd Street Grounds (6-1) | 43-24 | Won 3 |
| » Starters: Jack Katoll vs Bill Reidy | Second | 3½ out |
| Friday, July 12 |
| » Defeated Brewers (22-45), 14-1 | South Side Park III (24-8) | 44-24 | Won 4 |
| » Starters: Pink Hawley vs Roy Patterson | Second | 3½ out |
| Saturday, July 13 |
| » Lost to Brewers (23-45), 3-2 | South Side Park III (24-9) | 44-25 | |
| » Starters: Tully Sparks vs Zaza Harvey | Second | 3½ out |
| Sunday, July 14 |
| » Defeated Brewers (23-46), 4-0 | South Side Park III (25-9) | 45-25 | |
| » Starters: Bill Reidy vs Clark Griffith | Second | 4 out |
| Wednesday, July 17 |
| » Defeated Orioles (34-27), 4-2 | South Side Park III (26-9) | 46-25 | Won 2 |
| » Starters: Jerry Nops vs Nixey Callahan | Second | 2½ out |
| Thursday, July 18 |
| » Defeated Orioles (34-28), 9-1 | South Side Park III (27-9) | 47-25 | Won 3 |
| » Starters: Joe McGinnity vs Roy Patterson | First | -- |
| Friday, July 19 |
| » Lost to Orioles (35-28), 7-4 | South Side Park III (27-10) | 47-26 | |
| » Starters: Harry Howell vs Zaza Harvey | First | -- |
| Saturday, July 20 |
| » Lost to Athletics (30-38), 8-6 | South Side Park III (27-11) | 47-27 | Lost 2 |
| » Starters: Chick Fraser vs Clark Griffith | First | -- |
| Sunday, July 21 |
| » Defeated Athletics (30-39), 9-4 | South Side Park III (28-11) | 48-27 | |
| » Starters: Bill Bernhard vs Nixey Callahan | First | -- |
| Monday, July 22 |
| » Lost to Athletics (31-39), 2-1 | South Side Park III (28-12) | 48-28 | |
| » Starters: Eddie Plank vs Roy Patterson | First | -- |
| Tuesday, July 23 |
| » Defeated Athletics (31-40), 10-6 | South Side Park III (29-12) | 49-28 | |
| » Starters: Snake Wiltse vs Jack Katoll | First | -- |
| Wednesday, July 24 |
| » Defeated Senators (31-35), 17-3 | South Side Park III (30-12) | 50-28 | Won 2 |
| » Starters: Casey Patten vs Nixey Callahan | First | -- |
| Thursday, July 25 |
| » Defeated Senators (31-36), 4-1 | South Side Park III (31-12) | 51-28 | Won 3 |
| » Starters: Watty Lee vs Roy Patterson | First | -- |
| Friday, July 26 |
| » Defeated Senators (31-37), 2-1 | South Side Park III (32-12) | 52-28 | Won 4 |
| » Starters: Bill Carrick vs Clark Griffith | First | -- |
| Saturday, July 27 |
| » Defeated Red Sox (46-30), 8-7 | South Side Park III (33-12) | 53-28 | Won 5 |
| » Starters: Fred Mitchell vs Nixey Callahan | First | -- |
| Monday, July 29 |
| » Lost to Red Sox (47-30), 4-1 | South Side Park III (33-13) | 53-29 | |
| » Starters: Cy Young vs Roy Patterson | First | -- |
| Wednesday, July 31 |
| » Defeated Tigers (44-37), 2-0 | South Side Park III (34-13) | 54-29 | |
| » Starters: Roscoe Miller vs Clark Griffith | First | -- |
| Thursday, August 1 |
| » Defeated Tigers (44-38), 4-0 | South Side Park III (35-13) | 55-29 | Won 2 |
| » Starters: Joe Yeager vs Nixey Callahan | First | -- |
| Friday, August 2 |
| » Defeated Tigers (44-39), 7-0 | South Side Park III (36-13) | 56-29 | Won 3 |
| » Starters: Ed Siever vs Roy Patterson | First | -- |
| Saturday, August 3 |
| » Lost to Tigers (45-39), 8-6 | South Side Park III (36-14) | 56-30 | |
| » Starters: Roscoe Miller vs Jack Katoll | First | -- |
| Sunday, August 4 |
| » Defeated Indians (32-50), 9-5 | South Side Park III (37-14) | 57-30 | |
| » Starters: Pete Dowling vs Clark Griffith | First | -- |
| Monday, August 5 |
| » Lost to Indians (33-50), 6-3 | South Side Park III (37-15) | 57-31 | |
| » Starters: Harry McNeal vs Roy Patterson | First | -- |
| Wednesday, August 7 |
| » Lost to Tigers (47-42), 9-3 | Bennett Park (2-4) | 57-32 | Lost 2 |
| » Starters: Nixey Callahan vs Joe Yeager | First | -- |
| Thursday, August 8 |
| » Defeated Tigers (47-43), 18-8 | Bennett Park (3-4) | 58-32 | |
| » Starters: Clark Griffith vs Ed Siever | First | -- |
| Friday, August 9 |
| » Lost to Tigers (48-43), 12-1 | Bennett Park (3-5) | 58-33 | |
| » Starters: Roy Patterson vs Roscoe Miller | First | -- |
| Saturday, August 10 |
| » Lost to Indians (37-50), 11-7 | League Park I (4-3) | 58-34 | Lost 2 |
| » Starters: Jack Katoll vs Harry McNeal | First | -- |
| Sunday, August 11 |
| » Lost to Indians (38-50), 4-3 | South Side Park III (37-16) | 58-35 | Lost 3 |
| » Starters: Jack Bracken vs Nixey Callahan | First | -- |
| Monday, August 12 |
| » Defeated Indians (38-51), 17-2 | League Park I (5-3) | 59-35 | |
| » Starters: Clark Griffith vs Pete Dowling | First | -- |
| Tuesday, August 13 |
| » Lost to Indians (39-51), 4-0 | League Park I (5-4) | 59-36 | |
| » Starters: Jack Katoll vs Earl Moore | First | -- |
| » Defeated Indians (39-52), 14-1 | League Park I (6-4) | 60-36 | |
| » Starters: Roy Patterson vs Harry McNeal | First | -- |
| Friday, August 16 |
| » Lost to Red Sox (56-40), 6-2 | Huntington Ave Baseball Grounds (0-6) | 60-37 | |
| » Starters: Nixey Callahan vs Cy Young | First | -- |
| Saturday, August 17 |
| » Lost to Red Sox (57-40), 4-2 | Huntington Ave Baseball Grounds (0-7) | 60-38 | Lost 2 |
| » Starters: Clark Griffith vs Ted Lewis | First | -- |
| Monday, August 19 |
| » Lost to Senators (40-54), 5-2 | American League Park I (2-3) | 60-39 | Lost 3 |
| » Starters: Roy Patterson vs Bill Carrick | First | -- |
| Tuesday, August 20 |
| » Defeated Senators (40-55), 9-3 | American League Park I (3-3) | 61-39 | |
| » Starters: Clark Griffith vs Casey Patten | First | -- |
| Wednesday, August 21 |
| » Lost to Senators (41-55), 8-0 | American League Park I (3-4) | 61-40 | |
| » Starters: Jack Katoll vs Win Mercer | First | -- |
| Thursday, August 22 |
| » Defeated Orioles (54-42), 6-5 | Oriole Park IV (3-1) | 62-40 | |
| » Starters: Roy Patterson vs Harry Howell | First | -- |
| Friday, August 23 |
| » Defeated Orioles (54-43), 6-4 | Oriole Park IV (4-1) | 63-40 | Won 2 |
| » Starters: Clark Griffith vs Jerry Nops | First | -- |
| Saturday, August 24 |
| » Lost to Orioles (55-43), 10-4 | Oriole Park IV (4-2) | 63-41 | |
| » Starters: Frank Dupee vs Frank Foreman | First | -- |
| Sunday, August 25 |
| » Major-league debuts: Terry Turner (Pirates) |
| Monday, August 26 |
| » Defeated Athletics (54-50), 11-4 | Columbia Park (5-0) | 64-41 | |
| » Starters: Roy Patterson vs Snake Wiltse | First | -- |
| Tuesday, August 27 |
| » Lost to Athletics (55-50), 7-5 | Columbia Park (5-1) | 64-42 | |
| » Starters: Nixey Callahan vs Bill Bernhard | First | -- |
| Wednesday, August 28 |
| » Defeated Athletics (55-51), 3-0 | Columbia Park (6-1) | 65-42 | |
| » Starters: Roy Patterson vs Chick Fraser | First | -- |
| Friday, August 30 |
| » Tied Orioles, 5-5 | South Side Park III (37-16) | 65-42 | |
| » Starters: Frank Foreman vs Jack Katoll | First | -- |
| Saturday, August 31 |
| » Defeated Orioles (56-45), 12-2 | South Side Park III (38-16) | 66-42 | Won 2 |
| » Starters: Jerry Nops vs Roy Patterson | First | -- |
| » Defeated Orioles (56-46), 5-2 | South Side Park III (39-16) | 67-42 | Won 3 |
| » Starters: Harry Howell vs Wiley Piatt | First | -- |
| Sunday, September 1 |
| » Defeated Orioles (56-47), 6-3 | South Side Park III (40-16) | 68-42 | Won 4 |
| » Starters: Jerry Nops vs Nixey Callahan | First | -- |
| Monday, September 2 |
| » Defeated Athletics (56-54), 2-0 | South Side Park III (41-16) | 69-42 | Won 5 |
| » Starters: Bill Bernhard vs Roy Patterson | First | -- |
| » Lost to Athletics (57-54), 10-9 | South Side Park III (41-17) | 69-43 | |
| » Starters: Snake Wiltse vs Wiley Piatt | First | -- |
| Tuesday, September 3 |
| » Lost to Athletics (58-54), 3-2 | South Side Park III (41-18) | 69-44 | Lost 2 |
| » Starters: Chick Fraser vs Nixey Callahan | First | -- |
| Wednesday, September 4 |
| » Defeated Senators (49-61), 9-5 | South Side Park III (42-18) | 70-44 | |
| » Starters: Bill Carrick vs Jack Katoll | First | -- |
| Thursday, September 5 |
| » Defeated Senators (49-62), 4-3 | South Side Park III (43-18) | 71-44 | Won 2 |
| » Starters: Bill Carrick vs Roy Patterson | First | -- |
| » Lost to Senators (50-62), 9-7 | South Side Park III (43-19) | 71-45 | |
| » Starters: Casey Patten vs Wiley Piatt | First | -- |
| Friday, September 6 |
| » Lost to Senators (51-62), 5-3 | South Side Park III (43-20) | 71-46 | Lost 2 |
| » Starters: Win Mercer vs Jack Katoll | First | -- |
| Saturday, September 7 |
| » Defeated Red Sox (67-49), 4-1 | South Side Park III (44-20) | 72-46 | |
| » Starters: Ted Lewis vs Nixey Callahan | First | -- |
| Sunday, September 8 |
| » Defeated Red Sox (67-50), 4-3 | South Side Park III (45-20) | 73-46 | Won 2 |
| » Starters: Cy Young vs Roy Patterson | First | -- |
| Monday, September 9 |
| » Defeated Red Sox (67-51), 4-3 | South Side Park III (46-20) | 74-46 | Won 3 |
| » Starters: Fred Mitchell vs Nixey Callahan | First | -- |
| » Defeated Red Sox (67-52), 6-4 | South Side Park III (47-20) | 75-46 | Won 4 |
| » Starters: George Winter vs Clark Griffith | First | -- |
| Tuesday, September 10 |
| » Defeated Brewers (44-76), 6-3 | Lloyd Street Grounds (7-1) | 76-46 | Won 5 |
| » Starters: Jack Katoll vs Ned Garvin | First | -- |
| Thursday, September 12 |
| » Lost to Brewers (45-76), 5-1 | Lloyd Street Grounds (7-2) | 76-47 | |
| » Starters: Roy Patterson vs Bert Husting | First | -- |
| » Defeated Brewers (45-77), 4-0 | Lloyd Street Grounds (8-2) | 77-47 | |
| » Starters: Wiley Piatt vs Bill Reidy | First | -- |
| Friday, September 13 |
| » Lost to Brewers (46-77), 5-3 | South Side Park III (47-21) | 77-48 | |
| » Starters: Ned Garvin vs Jack Katoll | First | -- |
| Sunday, September 15 |
| » Defeated Brewers (46-78), 5-4 | South Side Park III (48-21) | 78-48 | |
| » Starters: Bert Husting vs Nixey Callahan | First | -- |
| » Defeated Brewers (46-79), 9-4 | South Side Park III (49-21) | 79-48 | Won 2 |
| » Starters: Bill Reidy vs Clark Griffith | First | -- |
| » Major-league debuts: Lou Gertenrich (Brewers) |
| Monday, September 16 |
| Future White Sox Ken Ash is born in Anmoore, WV. |
| Wednesday, September 18 |
| » Defeated Orioles (60-61), 10-3 | Oriole Park IV (5-2) | 80-48 | Won 3 |
| » Starters: Roy Patterson vs Joe McGinnity | First | -- |
| » Defeated Orioles (60-62), 5-1 | Oriole Park IV (6-2) | 81-48 | Won 4 |
| » Starters: Nixey Callahan vs Jerry Nops | First | -- |
| Friday, September 20 |
| » Defeated Athletics (67-61), 8-3 | Columbia Park (7-1) | 82-48 | Won 5 |
| » Starters: Clark Griffith vs Chick Fraser | First | -- |
| Saturday, September 21 |
| » Lost to Athletics (68-61), 10-4 | Columbia Park (7-2) | 82-49 | |
| » Starters: Roy Patterson vs Bill Bernhard | First | -- |
| Monday, September 23 |
| » Lost to Athletics (69-61), 5-3 | Columbia Park (7-3) | 82-50 | Lost 2 |
| » Starters: Clark Griffith vs Eddie Plank | First | -- |
| Tuesday, September 24 |
| » Lost to Red Sox (74-57), 8-3 | Huntington Ave Baseball Grounds (0-8) | 82-51 | Lost 3 |
| » Starters: Wiley Piatt vs George Winter | First | -- |
| Wednesday, September 25 |
| » Lost to Red Sox (75-57), 5-2 | Huntington Ave Baseball Grounds (0-9) | 82-52 | Lost 4 |
| » Starters: Nixey Callahan vs Cy Young | First | -- |
| Thursday, September 26 |
| » Lost to Red Sox (76-57), 3-2 | Huntington Ave Baseball Grounds (0-10) | 82-53 | Lost 5 |
| » Starters: Nixey Callahan vs Ted Lewis | First | -- |
| Friday, September 27 |
| » Defeated Senators (61-72), 6-4 | American League Park I (4-4) | 83-53 | |
| » Starters: Wiley Piatt vs Bill Carrick | First | -- |
| Saturday, October 5 |
| » Major-league debuts: Germany Schaefer (Cubs) |
| Friday, November 15 |
| Future White Sox John Dobb is born in Muskegon, MI. |
| Sunday, December 1 |
| Future White Sox Mike Cvengros is born in Pana, IL. |
| Tuesday, December 3 |
| Future White Sox Bennie Tate is born in Whitwell, TN. |
Game information provided by Retrosheet (www.retrosheet.org) |