| Sunday, February 17 |
| Future Tiger Eddie Phillips is born in Worcester, MA. |
| Tuesday, April 9 |
| Future Tiger Vic Sorrell is born in Morrisville, NC. |
| Thursday, April 18 |
| » Major-league debuts: Lefty Davis (Dodgers) |
| Friday, April 19 |
| » Major-league debuts: Jim Delahanty (Cubs) |
| Future Tiger Bernie DeViveiros is born in Oakland, CA. |
| Saturday, April 20 |
| » Major-league debuts: John Dobbs (Reds) |
| Monday, April 22 |
| » Major-league debuts: Doc White (Phillies) |
| Wednesday, April 24 |
| » Major-league debuts: Dave Brain (White Sox) |
| Thursday, April 25 |
| » Defeated Brewers (0-1), 14-13 | Bennett Park (1-0) | 1-0 | |
| » Starters: Pink Hawley vs Roscoe Miller | Second | ½ out |
| » Major-league debuts: Billy Gilbert (Brewers) |
| Friday, April 26 |
| » Defeated Brewers (0-2), 6-5 | Bennett Park (2-0) | 2-0 | Won 2 |
| » Starters: Ned Garvin vs Frank Owen | First | -- |
| » Major-league debuts: Frank Owen and Ed Siever (Tigers) |
| Saturday, April 27 |
| » Defeated Brewers (0-3), 13-9 | Bennett Park (3-0) | 3-0 | Won 3 |
| » Starters: Bert Husting vs Joe Yeager | First | -- |
| Sunday, April 28 |
| » Defeated Brewers (0-4), 12-11 | Burns Park (1-0) | 4-0 | Won 4 |
| » Starters: Pete Dowling vs Ed Siever | First | -- |
| Monday, April 29 |
| » Defeated White Sox (3-2), 3-2 | South Side Park III (1-0) | 5-0 | Won 5 |
| » Starters: Frank Owen vs Roy Patterson | First | -- |
| Tuesday, April 30 |
| » Lost to White Sox (4-2), 4-2 | South Side Park III (1-1) | 5-1 | |
| » Starters: Jack Cronin vs John Skopec | Second | 1 out |
| Wednesday, May 1 |
| » Lost to White Sox (5-2), 19-9 | South Side Park III (1-2) | 5-2 | Lost 2 |
| » Starters: Joe Yeager vs Zaza Harvey | Second | 1 out |
| Thursday, May 2 |
| » White Sox forfeited to Tigers. | South Side Park III (2-2) | 6-2 | |
| » Starters: Emil Frisk vs Clark Griffith | First | -- |
| Friday, May 3 |
| » Defeated Indians (3-6), 6-3 | Bennett Park (4-0) | 7-2 | Won 2 |
| » Starters: Bill Hoffer vs Ed Siever | First | -- |
| Saturday, May 4 |
| » Lost to Indians (4-6), 11-4 | Bennett Park (4-1) | 7-3 | |
| » Starters: Earl Moore vs Jack Cronin | First | -- |
| Sunday, May 5 |
| » Defeated Indians (4-7), 10-3 | Burns Park (2-0) | 8-3 | |
| » Starters: Ed Scott vs Ed Siever | First | -- |
| Monday, May 6 |
| » Defeated Indians (4-8), 5-4 | Bennett Park (5-1) | 9-3 | Won 2 |
| » Starters: Bill Hart vs Joe Yeager | First | -- |
| Tuesday, May 7 |
| » Defeated Brewers (3-10), 9-2 | Lloyd Street Grounds (1-0) | 10-3 | Won 3 |
| » Starters: Emil Frisk vs Tully Sparks | First | -- |
| Thursday, May 9 |
| » Lost to Brewers (4-10), 7-6 | Lloyd Street Grounds (1-1) | 10-4 | |
| » Starters: Frank Owen vs Bill Reidy | First | -- |
| Friday, May 10 |
| » Defeated Brewers (4-11), 7-6 | Lloyd Street Grounds (2-1) | 11-4 | |
| » Starters: Jack Cronin vs Bert Husting | First | -- |
| Saturday, May 11 |
| » Defeated White Sox (11-5), 9-4 | Bennett Park (6-1) | 12-4 | Won 2 |
| » Starters: John Skopec vs Joe Yeager | First | -- |
| Sunday, May 12 |
| » Defeated White Sox (11-6), 7-5 | Burns Park (3-0) | 13-4 | Won 3 |
| » Starters: Jack Katoll vs Ed Siever | First | -- |
| Monday, May 13 |
| » Defeated White Sox (11-7), 8-7 | Bennett Park (7-1) | 14-4 | Won 4 |
| » Starters: Zaza Harvey vs Roscoe Miller | First | -- |
| Tuesday, May 14 |
| » Lost to White Sox (12-7), 6-2 | Bennett Park (7-2) | 14-5 | |
| » Starters: Clark Griffith vs Ed Siever | First | -- |
| Thursday, May 16 |
| » Defeated Indians (4-16), 5-2 | League Park I (1-0) | 15-5 | |
| » Starters: Joe Yeager vs Dick Braggins | First | -- |
| Friday, May 17 |
| » Defeated Indians (4-17), 6-4 | League Park I (2-0) | 16-5 | Won 2 |
| » Starters: Jack Cronin vs Bill Hoffer | First | -- |
| Saturday, May 18 |
| » Lost to Indians (5-17), 9-7 | League Park I (2-1) | 16-6 | |
| » Starters: Roscoe Miller vs Ed Scott | First | -- |
| Sunday, May 19 |
| » Lost to Indians (6-17), 11-2 | Burns Park (3-1) | 16-7 | Lost 2 |
| » Starters: Earl Moore vs Ed Siever | First | -- |
| Monday, May 20 |
| » Defeated Indians (6-18), 13-1 | League Park I (3-1) | 17-7 | |
| » Starters: Emil Frisk vs Bill Hart | First | -- |
| » Major-league debuts: Frank Cross (Indians) |
| Wednesday, May 22 |
| » Lost to Red Sox (9-10), 9-5 | Bennett Park (7-3) | 17-8 | |
| » Starters: Ted Lewis vs Ed Siever | First | -- |
| Thursday, May 23 |
| » Lost to Red Sox (10-10), 4-2 | Bennett Park (7-4) | 17-9 | Lost 2 |
| » Starters: Cy Young vs Jack Cronin | Second | ½ out |
| Friday, May 24 |
| » Defeated Red Sox (10-11), 3-0 | Bennett Park (8-4) | 18-9 | |
| » Starters: Ben Beville vs Roscoe Miller | Second | 1 out |
| Saturday, May 25 |
| » Lost to Senators (13-9), 6-5 | Bennett Park (8-5) | 18-10 | |
| » Starters: Watty Lee vs Emil Frisk | Second | 1 out |
| Monday, May 27 |
| » Lost to Senators (14-9), 8-4 | Bennett Park (8-6) | 18-11 | Lost 2 |
| » Starters: Bill Carrick vs Roscoe Miller | Second | 2½ out |
| Thursday, May 30 |
| » Lost to Orioles (13-10), 10-7 | Bennett Park (8-7) | 18-12 | Lost 3 |
| » Starters: Jack Dunn vs Emil Frisk | Second | 3½ out |
| » Defeated Orioles (13-11), 4-1 | Bennett Park (9-7) | 19-12 | |
| » Starters: Joe McGinnity vs Jack Cronin | Second | 3½ out |
| Friday, May 31 |
| » Baltimore forfeited to Detroit. | Bennett Park (10-7) | 20-12 | Won 2 |
| » Starters: Harry Howell vs Ed Siever | Second | 4 out |
| Saturday, June 1 |
| » Lost to Orioles (14-11), 3-1 | Bennett Park (10-8) | 20-13 | |
| » Starters: Joe McGinnity vs Roscoe Miller | Second | 4 out |
| Sunday, June 2 |
| » Lost to Athletics (15-17), 11-8 | Burns Park (3-2) | 20-14 | Lost 2 |
| » Starters: Bill Bernhard vs Emil Frisk | Third | 4 out |
| Monday, June 3 |
| » Lost to Athletics (16-17), 2-1 | Bennett Park (10-9) | 20-15 | Lost 3 |
| » Starters: Eddie Plank vs Roscoe Miller | Fourth | 4 out |
| Tuesday, June 4 |
| » Defeated Athletics (16-18), 9-1 | Bennett Park (11-9) | 21-15 | |
| » Starters: Chick Fraser vs Ed Siever | Third | 4 out |
| Wednesday, June 5 |
| » Defeated Athletics (16-19), 3-2 | Bennett Park (12-9) | 22-15 | Won 2 |
| » Starters: Wiley Piatt vs Jack Cronin | Third | 3½ out |
| Thursday, June 6 |
| » Major-league debuts: Burt Hart (Orioles) |
| Saturday, June 8 |
| » Lost to Athletics (17-19), 6-1 | Columbia Park (0-1) | 22-16 | |
| » Starters: Joe Yeager vs Eddie Plank | Third | 4 out |
| » Major-league debuts: Al Shaw (Tigers) |
| Monday, June 10 |
| » Defeated Athletics (17-20), 5-4 | Columbia Park (1-1) | 23-16 | |
| » Starters: Roscoe Miller vs Wiley Piatt | Second | 4 out |
| Tuesday, June 11 |
| » Defeated Athletics (17-21), 4-1 | Columbia Park (2-1) | 24-16 | Won 2 |
| » Starters: Jack Cronin vs Chick Fraser | Second | 3 out |
| Wednesday, June 12 |
| » Lost to Red Sox (19-16), 4-2 | Huntington Ave Baseball Grounds (0-1) | 24-17 | |
| » Starters: Ed Siever vs Cy Young | Second | 3 out |
| Thursday, June 13 |
| » Defeated Red Sox (19-17), 11-6 | Huntington Ave Baseball Grounds (1-1) | 25-17 | |
| » Starters: Roscoe Miller vs Ted Lewis | Second | 3 out |
| Friday, June 14 |
| » Lost to Red Sox (20-17), 16-7 | Huntington Ave Baseball Grounds (1-2) | 25-18 | |
| » Starters: Jack Cronin vs Win Kellum | Second | 4 out |
| Saturday, June 15 |
| » Lost to Red Sox (21-17), 12-4 | Huntington Ave Baseball Grounds (1-3) | 25-19 | Lost 2 |
| » Starters: Frank Owen vs George Winter | Second | 4½ out |
| » Major-league debuts: George Winter (Red Sox) |
| Monday, June 17 |
| » Defeated Senators (19-17), 9-2 | American League Park I (1-0) | 26-19 | |
| » Starters: Roscoe Miller vs Watty Lee | Third | 3 out |
| Tuesday, June 18 |
| » Defeated Senators (19-18), 10-6 | American League Park I (2-0) | 27-19 | Won 2 |
| » Starters: Jack Cronin vs Bill Carrick | Third | 2 out |
| Wednesday, June 19 |
| » Lost to Senators (20-18), 7-2 | American League Park I (2-1) | 27-20 | |
| » Starters: Ed Siever vs Casey Patten | Third | 2 out |
| Thursday, June 20 |
| » Lost to Senators (21-18), 8-7 | American League Park I (2-2) | 27-21 | Lost 2 |
| » Starters: Roscoe Miller vs Dale Gear | Third | 2 out |
| Friday, June 21 |
| » Lost to Orioles (21-19), 4-3 | Oriole Park IV (0-1) | 27-22 | Lost 3 |
| » Starters: Jack Cronin vs Joe McGinnity | Third | 3 out |
| Saturday, June 22 |
| » Lost to Orioles (22-19), 10-3 | Oriole Park IV (0-2) | 27-23 | Lost 4 |
| » Starters: Emil Frisk vs Harry Howell | Fourth | 4 out |
| Monday, June 24 |
| » Lost to Orioles (23-19), 17-8 | Oriole Park IV (0-3) | 27-24 | Lost 5 |
| » Starters: Roscoe Miller vs Frank Foreman | Fifth | 5 out |
| Tuesday, June 25 |
| » Lost to Orioles (24-19), 4-2 | Oriole Park IV (0-4) | 27-25 | Lost 6 |
| » Starters: Ed Siever vs Jerry Nops | Fifth | 6 out |
| Thursday, June 27 |
| » Defeated Brewers (19-33), 4-3 | Bennett Park (13-9) | 28-25 | |
| » Starters: Tully Sparks vs Jack Cronin | Fifth | 6 out |
| Friday, June 28 |
| » Defeated Brewers (19-34), 4-0 | Bennett Park (14-9) | 29-25 | Won 2 |
| » Starters: Ned Garvin vs Roscoe Miller | Fifth | 6 out |
| Saturday, June 29 |
| » Defeated Brewers (19-35), 5-0 | Bennett Park (15-9) | 30-25 | Won 3 |
| » Starters: Pink Hawley vs Ed Siever | Fourth | 6 out |
| Sunday, June 30 |
| » Lost to White Sox (37-20), 4-2 | South Side Park III (2-3) | 30-26 | |
| » Starters: Jack Cronin vs Nixey Callahan | Fifth | 7 out |
| Tuesday, July 2 |
| » Lost to White Sox (38-20), 3-2 | South Side Park III (2-4) | 30-27 | Lost 2 |
| » Starters: Ed Siever vs Clark Griffith | Fifth | 8 out |
| Wednesday, July 3 |
| » Defeated Brewers (19-39), 7-5 | Lloyd Street Grounds (3-1) | 31-27 | |
| » Starters: Roscoe Miller vs Ned Garvin | Fifth | 8 out |
| Thursday, July 4 |
| » Defeated Brewers (19-40), 5-1 | Lloyd Street Grounds (4-1) | 32-27 | Won 2 |
| » Starters: Ed High vs Tully Sparks | Fourth | 7 out |
| » Lost to Brewers (20-40), 8-7 | Lloyd Street Grounds (4-2) | 32-28 | |
| » Starters: Jack Cronin vs Bill Reidy | Fourth | 7 out |
| Friday, July 5 |
| » Lost to White Sox (40-22), 8-4 | Bennett Park (15-10) | 32-29 | Lost 2 |
| » Starters: Clark Griffith vs Ed Siever | Fourth | 8 out |
| Saturday, July 6 |
| » Defeated White Sox (40-23), 6-5 | Bennett Park (16-10) | 33-29 | |
| » Starters: Jack Katoll vs Roscoe Miller | Fourth | 7 out |
| Sunday, July 7 |
| » Defeated White Sox (40-24), 8-3 | Burns Park (4-2) | 34-29 | Won 2 |
| » Starters: Roy Patterson vs Jack Cronin | Fourth | 6½ out |
| Tuesday, July 9 |
| » Defeated Indians (24-38), 11-1 | League Park I (4-1) | 35-29 | Won 3 |
| » Starters: Ed Siever vs Bill Hart | Fourth | 6½ out |
| Wednesday, July 10 |
| » Defeated Indians (24-39), 7-4 | League Park I (5-1) | 36-29 | Won 4 |
| » Starters: Roscoe Miller vs Pete Dowling | Fourth | 5½ out |
| Thursday, July 11 |
| » Lost to Indians (25-39), 6-1 | League Park I (5-2) | 36-30 | |
| » Starters: Jack Cronin vs Earl Moore | Fourth | 6½ out |
| Friday, July 12 |
| » Lost to Indians (26-39), 5-2 | Bennett Park (16-11) | 36-31 | Lost 2 |
| » Starters: Ed Scott vs Ed Siever | Fourth | 7½ out |
| Saturday, July 13 |
| » Defeated Indians (26-40), 19-12 | Bennett Park (17-11) | 37-31 | |
| » Starters: Gus Weyhing vs Roscoe Miller | Fourth | 6½ out |
| Sunday, July 14 |
| » Defeated Indians (26-41), 5-0 | Burns Park (5-2) | 38-31 | Won 2 |
| » Starters: Pete Dowling vs Joe Yeager | Fourth | 6 out |
| Tuesday, July 16 |
| » Lost to Senators (29-31), 8-5 | Bennett Park (17-12) | 38-32 | |
| » Starters: Casey Patten vs Jack Cronin | Fourth | 7½ out |
| Wednesday, July 17 |
| » Defeated Senators (29-32), 4-3 | Bennett Park (18-12) | 39-32 | |
| » Starters: Dale Gear vs Ed Siever | Fourth | 7 out |
| Thursday, July 18 |
| » Lost to Senators (30-32), 8-6 | Bennett Park (18-13) | 39-33 | |
| » Starters: Watty Lee vs Joe Yeager | Fourth | 8½ out |
| Friday, July 19 |
| » Defeated Senators (30-33), 7-3 | Bennett Park (19-13) | 40-33 | |
| » Starters: Bill Carrick vs Roscoe Miller | Fourth | 7½ out |
| Saturday, July 20 |
| » Defeated Red Sox (43-26), 8-6 | Bennett Park (20-13) | 41-33 | Won 2 |
| » Starters: Ted Lewis vs Ed Siever | Fourth | 6½ out |
| Future Tiger Heinie Manush is born in Tuscumbia, AL. |
| Sunday, July 21 |
| » Lost to Red Sox (44-26), 4-3 | Burns Park (5-3) | 41-34 | |
| » Starters: George Winter vs Joe Yeager | Fourth | 7½ out |
| Monday, July 22 |
| » Defeated Red Sox (44-27), 6-5 | Bennett Park (21-13) | 42-34 | |
| » Starters: Cy Young vs Roscoe Miller | Fourth | 6½ out |
| Wednesday, July 24 |
| » Lost to Athletics (32-40), 12-5 | Bennett Park (21-14) | 42-35 | |
| » Starters: Chick Fraser vs Jack Cronin | Fourth | 8 out |
| Thursday, July 25 |
| » Defeated Athletics (32-41), 4-3 | Bennett Park (22-14) | 43-35 | |
| » Starters: Eddie Plank vs Roscoe Miller | Fourth | 8 out |
| Saturday, July 27 |
| » Defeated Orioles (41-30), 1-0 | Bennett Park (23-14) | 44-35 | Won 2 |
| » Starters: Joe McGinnity vs Joe Yeager | Fourth | 8½ out |
| Sunday, July 28 |
| » Defeated Orioles (41-31), 6-4 | Burns Park (6-3) | 45-35 | Won 3 |
| » Starters: Harry Howell vs Ed Siever | Fourth | 8 out |
| Monday, July 29 |
| » Lost to Orioles (42-31), 10-5 | Bennett Park (23-15) | 45-36 | |
| » Starters: Jerry Nops vs Jack Cronin | Fourth | 8 out |
| Wednesday, July 31 |
| » Lost to White Sox (54-29), 2-0 | South Side Park III (2-5) | 45-37 | Lost 2 |
| » Starters: Roscoe Miller vs Clark Griffith | Fourth | 9 out |
| Thursday, August 1 |
| » Lost to White Sox (55-29), 4-0 | South Side Park III (2-6) | 45-38 | Lost 3 |
| » Starters: Joe Yeager vs Nixey Callahan | Fourth | 10 out |
| Friday, August 2 |
| » Lost to White Sox (56-29), 7-0 | South Side Park III (2-7) | 45-39 | Lost 4 |
| » Starters: Ed Siever vs Roy Patterson | Fourth | 11 out |
| Saturday, August 3 |
| » Defeated White Sox (56-30), 8-6 | South Side Park III (3-7) | 46-39 | |
| » Starters: Roscoe Miller vs Jack Katoll | Fourth | 10 out |
| Sunday, August 4 |
| » Lost to Brewers (31-56), 4-3 | Lloyd Street Grounds (4-3) | 46-40 | |
| » Starters: Joe Yeager vs Ned Garvin | Fourth | 11½ out |
| » Lost to Brewers (32-56), 11-4 | Lloyd Street Grounds (4-4) | 46-41 | Lost 2 |
| » Starters: Jack Cronin vs Pink Hawley | Fourth | 11½ out |
| Monday, August 5 |
| » Lost to Brewers (33-56), 19-4 | Lloyd Street Grounds (4-5) | 46-42 | Lost 3 |
| » Starters: Jack Cronin vs Bert Husting | Fourth | 11½ out |
| Tuesday, August 6 |
| » Defeated Brewers (33-57), 8-4 | Lloyd Street Grounds (5-5) | 47-42 | |
| » Starters: Roscoe Miller vs Tully Sparks | Fourth | 11 out |
| Wednesday, August 7 |
| » Defeated White Sox (57-32), 9-3 | Bennett Park (24-15) | 48-42 | Won 2 |
| » Starters: Nixey Callahan vs Joe Yeager | Fourth | 10 out |
| Thursday, August 8 |
| » Lost to White Sox (58-32), 18-8 | Bennett Park (24-16) | 48-43 | |
| » Starters: Clark Griffith vs Ed Siever | Fourth | 11 out |
| Friday, August 9 |
| » Defeated White Sox (58-33), 12-1 | Bennett Park (25-16) | 49-43 | |
| » Starters: Roy Patterson vs Roscoe Miller | Fourth | 10 out |
| Saturday, August 10 |
| » Lost to Brewers (34-60), 4-3 | Bennett Park (25-17) | 49-44 | |
| » Starters: Bert Husting vs Joe Yeager | Fourth | 10 out |
| Sunday, August 11 |
| » Defeated Brewers (34-61), 16-5 | Burns Park (7-3) | 50-44 | |
| » Starters: Bill Reidy vs Ed Siever | Fourth | 9 out |
| Monday, August 12 |
| » Lost to Brewers (35-61), 6-4 | Bennett Park (25-18) | 50-45 | |
| » Starters: Ned Garvin vs Roscoe Miller | Fourth | 10 out |
| Friday, August 16 |
| » Defeated Senators (38-53), 5-1 | American League Park I (3-2) | 51-45 | |
| » Starters: Joe Yeager vs Watty Lee | Fourth | 9 out |
| Saturday, August 17 |
| » Lost to Senators (39-53), 5-1 | American League Park I (3-3) | 51-46 | |
| » Starters: Ed Siever vs Win Mercer | Fourth | 8½ out |
| » Defeated Senators (39-54), 2-0 | American League Park I (4-3) | 52-46 | |
| » Starters: Roscoe Miller vs Casey Patten | Fourth | 8½ out |
| Monday, August 19 |
| » Lost to Orioles (54-40), 4-3 | Oriole Park IV (0-5) | 52-47 | |
| » Starters: Joe Yeager vs Jerry Nops | Fourth | 8½ out |
| Tuesday, August 20 |
| » Defeated Orioles (54-41), 5-2 | Oriole Park IV (1-5) | 53-47 | |
| » Starters: Ed Siever vs Harry Howell | Fourth | 8½ out |
| Wednesday, August 21 |
| » Orioles forfeited to Tigers. | Oriole Park IV (2-5) | 54-47 | Won 2 |
| Thursday, August 22 |
| » Lost to Athletics (53-49), 1-0 | Columbia Park (2-2) | 54-48 | |
| » Starters: Roscoe Miller vs Bill Bernhard | Fifth | 9 out |
| Friday, August 23 |
| » Lost to Athletics (54-49), 7-2 | Columbia Park (2-3) | 54-49 | Lost 2 |
| » Starters: Joe Yeager vs Chick Fraser | Fifth | 10 out |
| Sunday, August 25 |
| » Major-league debuts: Terry Turner (Pirates) |
| Monday, August 26 |
| » Defeated Red Sox (62-42), 6-3 | Huntington Ave Baseball Grounds (2-3) | 55-49 | |
| » Starters: Ed Siever vs George Winter | Fourth | 9½ out |
| Tuesday, August 27 |
| » Lost to Red Sox (63-42), 2-1 | Huntington Ave Baseball Grounds (2-4) | 55-50 | |
| » Starters: Roscoe Miller vs Cy Young | Fifth | 9½ out |
| Wednesday, August 28 |
| » Defeated Red Sox (63-43), 4-2 | Huntington Ave Baseball Grounds (3-4) | 56-50 | |
| » Starters: Joe Yeager vs Ted Lewis | Fifth | 9½ out |
| Thursday, August 29 |
| » Defeated Red Sox (63-44), 5-3 | Bennett Park (26-18) | 57-50 | Won 2 |
| » Starters: George Winter vs Ed Siever | Fourth | 9 out |
| Friday, August 30 |
| » Lost to Red Sox (64-44), 5-4 | Bennett Park (26-19) | 57-51 | |
| » Starters: Cy Young vs Jack Cronin | Fifth | 9½ out |
| Saturday, August 31 |
| » Defeated Red Sox (64-45), 6-5 | Bennett Park (27-19) | 58-51 | |
| » Starters: Fred Mitchell vs Roscoe Miller | Fourth | 10 out |
| » Tied Red Sox, 4-4 | Bennett Park (27-19) | 58-51 | |
| » Starters: Ted Lewis vs Joe Yeager | Fourth | 10 out |
| Sunday, September 1 |
| » Lost to Senators (48-58), 9-4 | Burns Park (7-4) | 58-52 | |
| » Starters: Bill Carrick vs Ed Siever | Fourth | 11 out |
| Monday, September 2 |
| » Defeated Senators (48-59), 5-2 | Bennett Park (28-19) | 59-52 | |
| » Starters: Casey Patten vs Jack Cronin | Fourth | 10 out |
| » Defeated Senators (48-60), 7-4 | Bennett Park (29-19) | 60-52 | Won 2 |
| » Starters: Dale Gear vs Roscoe Miller | Fourth | 10 out |
| Tuesday, September 3 |
| » Lost to Senators (49-60), 4-2 | Bennett Park (29-20) | 60-53 | |
| » Starters: Win Mercer vs Joe Yeager | Fourth | 10 out |
| Wednesday, September 4 |
| » Defeated Athletics (58-55), 9-1 | Bennett Park (30-20) | 61-53 | |
| » Starters: Eddie Plank vs Jack Cronin | Fourth | 10 out |
| Thursday, September 5 |
| » Lost to Athletics (59-55), 11-9 | Bennett Park (30-21) | 61-54 | |
| » Starters: Bill Bernhard vs Roscoe Miller | Fifth | 11 out |
| » Lost to Athletics (60-55), 9-2 | Bennett Park (30-22) | 61-55 | Lost 2 |
| » Starters: Snake Wiltse vs Frank Owen | Fifth | 11 out |
| Friday, September 6 |
| » Defeated Athletics (60-56), 8-3 | Bennett Park (31-22) | 62-55 | |
| » Starters: Chick Fraser vs Joe Yeager | Fourth | 10 out |
| Saturday, September 7 |
| » Defeated Orioles (58-54), 9-2 | Bennett Park (32-22) | 63-55 | Won 2 |
| » Starters: Joe McGinnity vs Ed Siever | Third | 10 out |
| Sunday, September 8 |
| » Defeated Orioles (58-55), 8-5 | Burns Park (8-4) | 64-55 | Won 3 |
| » Starters: Jerry Nops vs Jack Cronin | Third | 10 out |
| Monday, September 9 |
| » Defeated Orioles (58-56), 8-4 | Bennett Park (33-22) | 65-55 | Won 4 |
| » Starters: Joe McGinnity vs Joe Yeager | Third | 10½ out |
| Tuesday, September 10 |
| » Major-league debuts: Jim McGuire (Indians) |
| Thursday, September 12 |
| » Defeated Indians (51-69), 5-4 | League Park I (6-2) | 66-55 | Won 5 |
| » Starters: Roscoe Miller vs Bill Cristall | Third | 10 out |
| » Defeated Indians (51-70), 4-3 | League Park I (7-2) | 67-55 | Won 6 |
| » Starters: Ed Siever vs Harry McNeal | Third | 10 out |
| Friday, September 13 |
| » Defeated Indians (51-71), 7-0 | League Park I (8-2) | 68-55 | Won 7 |
| » Starters: Jack Cronin vs Pete Dowling | Third | 9 out |
| Saturday, September 14 |
| » Lost to Indians (52-71), 5-3 | Bennett Park (33-23) | 68-56 | |
| » Starters: Earl Moore vs Joe Yeager | Third | 9½ out |
| Sunday, September 15 |
| » Defeated Indians (52-72), 21-0 | Burns Park (9-4) | 69-56 | |
| » Starters: Jack Bracken vs Ed Siever | Third | 10 out |
| Tuesday, September 17 |
| » Lost to Athletics (67-60), 4-1 | Columbia Park (2-4) | 69-57 | |
| » Starters: Roscoe Miller vs Snake Wiltse | Third | 10½ out |
| Friday, September 20 |
| » Lost to Red Sox (73-54), 5-2 | Huntington Ave Baseball Grounds (3-5) | 69-58 | Lost 2 |
| » Starters: Jack Cronin vs Ted Lewis | Third | 12½ out |
| Saturday, September 21 |
| » Defeated Red Sox (73-55), 3-1 | Huntington Ave Baseball Grounds (4-5) | 70-58 | |
| » Starters: Ed Siever vs George Winter | Third | 11½ out |
| Monday, September 23 |
| » Defeated Red Sox (73-56), 5-4 | Huntington Ave Baseball Grounds (5-5) | 71-58 | Won 2 |
| » Starters: Joe Yeager vs Cy Young | Third | 10 out |
| » Defeated Red Sox (73-57), 9-2 | Huntington Ave Baseball Grounds (6-5) | 72-58 | Won 3 |
| » Starters: Roscoe Miller vs Ted Lewis | Third | 10 out |
| Tuesday, September 24 |
| » Lost to Senators (60-70), 4-1 | American League Park I (4-4) | 72-59 | |
| » Starters: Jack Cronin vs Bill Carrick | Third | 10 out |
| Wednesday, September 25 |
| » Lost to Senators (61-70), 3-2 | American League Park I (4-5) | 72-60 | Lost 2 |
| » Starters: Roscoe Miller vs Casey Patten | Fourth | 10 out |
| Thursday, September 26 |
| » Defeated Senators (61-71), 5-3 | American League Park I (5-5) | 73-60 | |
| » Starters: Joe Yeager vs Win Mercer | Third | 9 out |
| Friday, September 27 |
| » Lost to Orioles (68-62), 6-4 | Oriole Park IV (2-6) | 73-61 | |
| » Starters: Ed Siever vs Frank Foreman | Third | 10 out |
| Saturday, September 28 |
| » Defeated Orioles (68-63), 5-2 | Oriole Park IV (3-6) | 74-61 | |
| » Starters: Roscoe Miller vs Joe McGinnity | Fourth | 9½ out |
| Saturday, October 5 |
| » Major-league debuts: Germany Schaefer (Cubs) |
| Sunday, October 27 |
| Future Tiger George Smith is born in Louisville, KY. |
| Friday, November 22 |
| Future Tiger Harry Rice is born in Ware Station, IL. |
Game information provided by Retrosheet (www.retrosheet.org) |
