| Saturday, January 5 |
| Future Senator Luke Sewell is born in Titus, AL. |
| Sunday, January 13 |
| Future Senator Fred Schulte is born in Belvidere, IL. |
| Thursday, January 24 |
| Future Senator Curly Ogden is born in Ogden, PA. |
| Sunday, February 17 |
| Future Senator Eddie Phillips is born in Worcester, MA. |
| Thursday, April 18 |
| » Major-league debuts: Lefty Davis (Dodgers) |
| Friday, April 19 |
| » Major-league debuts: Jim Delahanty (Cubs) |
| Saturday, April 20 |
| » Major-league debuts: John Dobbs (Reds) |
| Monday, April 22 |
| » Major-league debuts: Doc White (Phillies) |
| Wednesday, April 24 |
| » Major-league debuts: Dave Brain (White Sox) |
| Thursday, April 25 |
| » Major-league debuts: Billy Gilbert (Brewers) |
| Friday, April 26 |
| » Defeated Athletics (0-1), 5-1 | Columbia Park (1-0) | 1-0 | |
| » Starters: Bill Carrick vs Chick Fraser | Second | ½ out |
| » Major-league debuts: John Farrell (Senators) |
| Saturday, April 27 |
| » Defeated Athletics (0-2), 11-5 | Columbia Park (2-0) | 2-0 | Won 2 |
| » Starters: Win Mercer vs Wiley Piatt | Second | ½ out |
| Monday, April 29 |
| » Defeated Orioles (2-1), 5-2 | American League Park I (1-0) | 3-0 | Won 3 |
| » Starters: Joe McGinnity vs Bill Carrick | Second | 1 out |
| Tuesday, April 30 |
| » Defeated Orioles (2-2), 12-6 | American League Park I (2-0) | 4-0 | Won 4 |
| » Starters: Roger Bresnahan vs Watty Lee | First | -- |
| » Major-league debuts: Watty Lee (Senators) |
| Wednesday, May 1 |
| » Lost to Orioles (3-2), 6-4 | American League Park I (2-1) | 4-1 | |
| » Starters: Joe McGinnity vs Win Mercer | First | -- |
| Thursday, May 2 |
| » Lost to Orioles (4-2), 11-4 | American League Park I (2-2) | 4-2 | Lost 2 |
| » Starters: Harry Howell vs Dale Gear | Second | 1 out |
| Friday, May 3 |
| » Defeated Red Sox (2-5), 9-4 | American League Park I (3-2) | 5-2 | |
| » Starters: Frank Foreman vs Bill Carrick | Second | 1 out |
| Saturday, May 4 |
| » Lost to Red Sox (3-5), 10-2 | American League Park I (3-3) | 5-3 | |
| » Starters: Cy Young vs Win Mercer | Second | 1 out |
| » Major-league debuts: Casey Patten (Senators) |
| Monday, May 6 |
| » Lost to Red Sox (4-5), 9-5 | American League Park I (3-4) | 5-4 | Lost 2 |
| » Starters: Ted Lewis vs Watty Lee | Third | 2½ out |
| Tuesday, May 7 |
| » Lost to Red Sox (5-5), 7-3 | American League Park I (3-5) | 5-5 | Lost 3 |
| » Starters: Win Kellum vs Bill Carrick | Fourth | 3½ out |
| Wednesday, May 8 |
| » Lost to Orioles (7-4), 5-1 | Oriole Park IV (0-1) | 5-6 | Lost 4 |
| » Starters: Win Mercer vs Joe McGinnity | Fifth | 4 out |
| Saturday, May 11 |
| » Defeated Red Sox (7-6), 3-2 | Huntington Ave Baseball Grounds (1-0) | 6-6 | |
| » Starters: Watty Lee vs Ted Lewis | Fifth | 4 out |
| Monday, May 13 |
| » Defeated Red Sox (7-7), 5-2 | Huntington Ave Baseball Grounds (2-0) | 7-6 | Won 2 |
| » Starters: Bill Carrick vs Win Kellum | Fourth | 4½ out |
| Tuesday, May 14 |
| » Defeated Red Sox (7-8), 3-2 | Huntington Ave Baseball Grounds (3-0) | 8-6 | Won 3 |
| » Starters: Dale Gear vs Cy Young | Fourth | 3½ out |
| Wednesday, May 15 |
| » Defeated Red Sox (7-9), 4-0 | Huntington Ave Baseball Grounds (4-0) | 9-6 | Won 4 |
| » Starters: Watty Lee vs Nig Cuppy | Fourth | 3 out |
| Thursday, May 16 |
| » Defeated Athletics (5-12), 12-5 | American League Park I (4-5) | 10-6 | Won 5 |
| » Starters: Chick Fraser vs Win Mercer | Fourth | 3 out |
| Friday, May 17 |
| » Defeated Athletics (5-13), 8-7 | American League Park I (5-5) | 11-6 | Won 6 |
| » Starters: Wiley Piatt vs Bill Carrick | Third | 3 out |
| Saturday, May 18 |
| » Lost to Athletics (6-13), 11-6 | American League Park I (5-6) | 11-7 | |
| » Starters: Eddie Plank vs Dale Gear | Fourth | 3 out |
| Monday, May 20 |
| » Defeated Athletics (6-14), 5-4 | American League Park I (6-6) | 12-7 | |
| » Starters: Chick Fraser vs Watty Lee | Fourth | 2½ out |
| Wednesday, May 22 |
| » Lost to Indians (7-18), 6-5 | League Park I (0-1) | 12-8 | |
| » Starters: Win Mercer vs Dick Braggins | Fourth | 2½ out |
| Future Senator Babe Ganzel is born in Malden, MA. |
| Thursday, May 23 |
| » Lost to Indians (8-18), 14-13 | League Park I (0-2) | 12-9 | Lost 2 |
| » Starters: Casey Patten vs Bill Hoffer | Fourth | 3 out |
| Friday, May 24 |
| » Tied Indians, 5-5 | League Park I (0-2) | 12-9 | |
| » Starters: Dale Gear vs Ed Scott | Fourth | 3 out |
| Saturday, May 25 |
| » Defeated Tigers (18-10), 6-5 | Bennett Park (1-0) | 13-9 | |
| » Starters: Watty Lee vs Emil Frisk | Fourth | 3 out |
| Monday, May 27 |
| » Defeated Tigers (18-11), 8-4 | Bennett Park (2-0) | 14-9 | Won 2 |
| » Starters: Bill Carrick vs Roscoe Miller | Third | 3½ out |
| Thursday, May 30 |
| » Lost to Brewers (11-18), 5-2 | Lloyd Street Grounds (0-1) | 14-10 | |
| » Starters: Watty Lee vs Tully Sparks | Third | 5½ out |
| » Lost to Brewers (12-18), 13-3 | Lloyd Street Grounds (0-2) | 14-11 | Lost 2 |
| » Starters: Win Mercer vs Bill Reidy | Third | 5½ out |
| Friday, May 31 |
| » Tied Brewers, 3-3 | Lloyd Street Grounds (0-2) | 14-11 | |
| » Starters: Bill Carrick vs Pink Hawley | Third | 6 out |
| Saturday, June 1 |
| » Defeated Brewers (12-19), 3-0 | Lloyd Street Grounds (1-2) | 15-11 | |
| » Starters: Dale Gear vs Ned Garvin | Third | 5 out |
| Sunday, June 2 |
| » Defeated White Sox (24-11), 7-5 | South Side Park III (1-0) | 16-11 | Won 2 |
| » Starters: Watty Lee vs Clark Griffith | Second | 4 out |
| Monday, June 3 |
| » Defeated White Sox (24-12), 5-3 | South Side Park III (2-0) | 17-11 | Won 3 |
| » Starters: Casey Patten vs Roy Patterson | Second | 4 out |
| Tuesday, June 4 |
| » Lost to White Sox (25-12), 3-2 | South Side Park III (2-1) | 17-12 | |
| » Starters: Dale Gear vs Jack Katoll | Second | 4 out |
| Thursday, June 6 |
| » Major-league debuts: Burt Hart (Orioles) |
| Friday, June 7 |
| » Lost to White Sox (26-12), 15-4 | American League Park I (6-7) | 17-13 | Lost 2 |
| » Starters: Clark Griffith vs Bill Carrick | Third | 5 out |
| Saturday, June 8 |
| » Defeated White Sox (26-13), 8-3 | American League Park I (7-7) | 18-13 | |
| » Starters: Roy Patterson vs Watty Lee | Second | 4 out |
| Monday, June 10 |
| » Lost to White Sox (27-13), 13-10 | American League Park I (7-8) | 18-14 | |
| » Starters: Jack Katoll vs Casey Patten | Third | 5 out |
| Tuesday, June 11 |
| » Defeated White Sox (27-14), 3-1 | American League Park I (8-8) | 19-14 | |
| » Starters: Zaza Harvey vs Watty Lee | Third | 4 out |
| Wednesday, June 12 |
| » Lost to Indians (14-25), 6-0 | American League Park I (8-9) | 19-15 | |
| » Starters: Earl Moore vs Bill Carrick | Third | 4 out |
| Saturday, June 15 |
| » Lost to Indians (15-25), 5-3 | American League Park I (8-10) | 19-16 | Lost 2 |
| » Starters: Ed Scott vs Dale Gear | Fourth | 5½ out |
| Monday, June 17 |
| » Lost to Tigers (25-19), 9-2 | American League Park I (8-11) | 19-17 | Lost 3 |
| » Starters: Roscoe Miller vs Watty Lee | Fourth | 5 out |
| Tuesday, June 18 |
| » Lost to Tigers (26-19), 10-6 | American League Park I (8-12) | 19-18 | Lost 4 |
| » Starters: Jack Cronin vs Bill Carrick | Fourth | 5 out |
| Wednesday, June 19 |
| » Defeated Tigers (26-20), 7-2 | American League Park I (9-12) | 20-18 | |
| » Starters: Ed Siever vs Casey Patten | Fourth | 5 out |
| Thursday, June 20 |
| » Defeated Tigers (26-21), 8-7 | American League Park I (10-12) | 21-18 | Won 2 |
| » Starters: Roscoe Miller vs Dale Gear | Fourth | 3 out |
| Friday, June 21 |
| » Lost to Brewers (17-30), 10-3 | American League Park I (10-13) | 21-19 | |
| » Starters: Bill Reidy vs Dale Gear | Fourth | 4 out |
| Saturday, June 22 |
| » Defeated Brewers (17-31), 2-0 | American League Park I (11-13) | 22-19 | |
| » Starters: Ned Garvin vs Casey Patten | Third | 4 out |
| Monday, June 24 |
| » Lost to Brewers (18-31), 9-8 | American League Park I (11-14) | 22-20 | |
| » Starters: Bert Husting vs Watty Lee | Fourth | 5 out |
| Tuesday, June 25 |
| » Defeated Brewers (18-32), 3-1 | American League Park I (12-14) | 23-20 | |
| » Starters: Pink Hawley vs Bill Carrick | Fourth | 5 out |
| Wednesday, June 26 |
| » Defeated Athletics (21-29), 5-4 | American League Park I (13-14) | 24-20 | Won 2 |
| » Starters: Bill Bernhard vs Casey Patten | Fourth | 4½ out |
| Thursday, June 27 |
| » Defeated Red Sox (29-19), 2-0 | American League Park I (14-14) | 25-20 | Won 3 |
| » Starters: Ted Lewis vs Watty Lee | Fourth | 4½ out |
| Friday, June 28 |
| » Lost to Red Sox (30-19), 6-5 | American League Park I (14-15) | 25-21 | |
| » Starters: George Winter vs Bill Carrick | Fourth | 5½ out |
| Saturday, June 29 |
| » Lost to Red Sox (31-19), 7-2 | American League Park I (14-16) | 25-22 | Lost 2 |
| » Starters: Cy Young vs Casey Patten | Fifth | 6½ out |
| Monday, July 1 |
| » Tied Athletics, 13-13 | American League Park I (14-16) | 25-22 | |
| » Starters: Eddie Plank vs Watty Lee | Fourth | 7 out |
| Tuesday, July 2 |
| » Defeated Athletics (21-33), 10-6 | American League Park I (15-16) | 26-22 | |
| » Starters: Wiley Piatt vs Casey Patten | Fourth | 7 out |
| Wednesday, July 3 |
| » Lost to Athletics (22-33), 9-7 | Columbia Park (2-1) | 26-23 | |
| » Starters: Win Mercer vs Bill Bernhard | Fourth | 8 out |
| » Major-league debuts: Matty McIntyre (Athletics) |
| Thursday, July 4 |
| » Lost to Athletics (23-33), 6-5 | Columbia Park (2-2) | 26-24 | Lost 2 |
| » Starters: Bill Carrick vs Eddie Plank | Fifth | 7½ out |
| Friday, July 5 |
| » Lost to Red Sox (36-20), 2-1 | Huntington Ave Baseball Grounds (4-1) | 26-25 | Lost 3 |
| » Starters: Watty Lee vs George Winter | Fifth | 8½ out |
| Saturday, July 6 |
| » Lost to Red Sox (37-20), 7-0 | Huntington Ave Baseball Grounds (4-2) | 26-26 | Lost 4 |
| » Starters: Watty Lee vs Cy Young | Fifth | 8½ out |
| Monday, July 8 |
| » Lost to Red Sox (38-20), 3-1 | Huntington Ave Baseball Grounds (4-3) | 26-27 | Lost 5 |
| » Starters: Bill Carrick vs Nig Cuppy | Fifth | 9½ out |
| Tuesday, July 9 |
| » Lost to Orioles (31-24), 3-1 | American League Park I (15-17) | 26-28 | Lost 6 |
| » Starters: Joe McGinnity vs Casey Patten | Fifth | 10 out |
| Wednesday, July 10 |
| » Lost to Orioles (32-24), 5-1 | American League Park I (15-18) | 26-29 | Lost 7 |
| » Starters: Frank Foreman vs Watty Lee | Fifth | 10 out |
| Thursday, July 11 |
| » Lost to Orioles (33-24), 6-2 | American League Park I (15-19) | 26-30 | Lost 8 |
| » Starters: Harry Howell vs Win Mercer | Fifth | 11 out |
| Friday, July 12 |
| » Defeated Orioles (33-25), 14-12 | Oriole Park IV (1-1) | 27-30 | |
| » Starters: Casey Patten vs Jerry Nops | Fifth | 11 out |
| Monday, July 15 |
| » Defeated Orioles (33-26), 3-2 | Oriole Park IV (2-1) | 28-30 | Won 2 |
| » Starters: Watty Lee vs Joe McGinnity | Fifth | 11½ out |
| » Lost to Orioles (34-26), 7-3 | Oriole Park IV (2-2) | 28-31 | |
| » Starters: Bill Carrick vs Frank Foreman | Fifth | 11½ out |
| Tuesday, July 16 |
| » Defeated Tigers (37-32), 8-5 | Bennett Park (3-0) | 29-31 | |
| » Starters: Casey Patten vs Jack Cronin | Fifth | 11 out |
| Wednesday, July 17 |
| » Lost to Tigers (38-32), 4-3 | Bennett Park (3-1) | 29-32 | |
| » Starters: Dale Gear vs Ed Siever | Fifth | 11½ out |
| Thursday, July 18 |
| » Defeated Tigers (38-33), 8-6 | Bennett Park (4-1) | 30-32 | |
| » Starters: Watty Lee vs Joe Yeager | Fifth | 12 out |
| Friday, July 19 |
| » Lost to Tigers (39-33), 7-3 | Bennett Park (4-2) | 30-33 | |
| » Starters: Bill Carrick vs Roscoe Miller | Fifth | 12 out |
| Saturday, July 20 |
| » Defeated Indians (28-45), 9-7 | League Park I (1-2) | 31-33 | |
| » Starters: Casey Patten vs Ed Scott | Fifth | 11 out |
| Future Senator Heinie Manush is born in Tuscumbia, AL. |
| Monday, July 22 |
| » Lost to Indians (29-45), 6-3 | League Park I (1-3) | 31-34 | |
| » Starters: Watty Lee vs Bill Hart | Fifth | 11½ out |
| Tuesday, July 23 |
| » Tied Indians, 4-4 | League Park I (1-3) | 31-34 | |
| » Starters: Bill Carrick vs Ed Scott | Fifth | 12 out |
| Wednesday, July 24 |
| » Lost to White Sox (50-28), 17-3 | South Side Park III (2-2) | 31-35 | Lost 2 |
| » Starters: Casey Patten vs Nixey Callahan | Fifth | 13 out |
| Thursday, July 25 |
| » Lost to White Sox (51-28), 4-1 | South Side Park III (2-3) | 31-36 | Lost 3 |
| » Starters: Watty Lee vs Roy Patterson | Fifth | 14 out |
| Friday, July 26 |
| » Lost to White Sox (52-28), 2-1 | South Side Park III (2-4) | 31-37 | Lost 4 |
| » Starters: Bill Carrick vs Clark Griffith | Fifth | 15 out |
| Saturday, July 27 |
| » Defeated Brewers (27-54), 7-0 | Lloyd Street Grounds (2-2) | 32-37 | |
| » Starters: Casey Patten vs Tully Sparks | Fifth | 15 out |
| Sunday, July 28 |
| » Lost to Brewers (28-54), 1-0 | Lloyd Street Grounds (2-3) | 32-38 | |
| » Starters: Dale Gear vs Ned Garvin | Fifth | 16 out |
| » Lost to Brewers (29-54), 9-4 | Lloyd Street Grounds (2-4) | 32-39 | Lost 2 |
| » Starters: Watty Lee vs Pink Hawley | Fifth | 16 out |
| Monday, July 29 |
| » Lost to Brewers (30-54), 9-1 | Lloyd Street Grounds (2-5) | 32-40 | Lost 3 |
| » Starters: Bill Carrick vs Bill Reidy | Fifth | 16 out |
| Wednesday, July 31 |
| » Lost to Orioles (43-31), 6-2 | Oriole Park IV (2-3) | 32-41 | Lost 4 |
| » Starters: Casey Patten vs Frank Foreman | Sixth | 17 out |
| Thursday, August 1 |
| » Lost to Orioles (44-31), 6-5 | Oriole Park IV (2-4) | 32-42 | Lost 5 |
| » Starters: Dale Gear vs Joe McGinnity | Sixth | 17½ out |
| » Defeated Orioles (44-32), 8-4 | Oriole Park IV (3-4) | 33-42 | |
| » Starters: Watty Lee vs Harry Howell | Sixth | 17½ out |
| Friday, August 2 |
| » Lost to Orioles (45-32), 5-4 | Oriole Park IV (3-5) | 33-43 | |
| » Starters: Bill Carrick vs Jerry Nops | Sixth | 18½ out |
| Saturday, August 3 |
| » Defeated Orioles (45-33), 6-5 | Oriole Park IV (4-5) | 34-43 | |
| » Starters: Casey Patten vs Frank Foreman | Sixth | 17 out |
| » Defeated Orioles (45-34), 8-5 | Oriole Park IV (5-5) | 35-43 | Won 2 |
| » Starters: Dale Gear vs Joe McGinnity | Sixth | 17 out |
| Monday, August 5 |
| » Lost to Athletics (37-43), 10-3 | Columbia Park (2-3) | 35-44 | |
| » Starters: Watty Lee vs Chick Fraser | Sixth | 18 out |
| » Lost to Athletics (38-43), 2-0 | Columbia Park (2-4) | 35-45 | Lost 2 |
| » Starters: Bill Carrick vs Snake Wiltse | Sixth | 18 out |
| Wednesday, August 7 |
| » Lost to Athletics (39-43), 4-1 | Columbia Park (2-5) | 35-46 | Lost 3 |
| » Starters: Win Mercer vs Bill Bernhard | Sixth | 17½ out |
| » Defeated Athletics (39-44), 7-3 | Columbia Park (3-5) | 36-46 | |
| » Starters: Casey Patten vs Eddie Plank | Sixth | 17½ out |
| Thursday, August 8 |
| » Lost to Athletics (40-44), 11-6 | Columbia Park (3-6) | 36-47 | |
| » Starters: Watty Lee vs Chick Fraser | Sixth | 19 out |
| » Lost to Athletics (41-44), 14-7 | Columbia Park (3-7) | 36-48 | Lost 2 |
| » Starters: Bill Carrick vs Snake Wiltse | Sixth | 19 out |
| Friday, August 9 |
| » Lost to Athletics (42-44), 5-4 | American League Park I (15-20) | 36-49 | Lost 3 |
| » Starters: Bill Bernhard vs Bill Carrick | Sixth | 19½ out |
| » Lost to Athletics (43-44), 9-4 | American League Park I (15-21) | 36-50 | Lost 4 |
| » Starters: Eddie Plank vs Casey Patten | Sixth | 19½ out |
| Saturday, August 10 |
| » Defeated Athletics (43-45), 9-4 | American League Park I (16-21) | 37-50 | |
| » Starters: Chick Fraser vs Win Mercer | Seventh | 19 out |
| » Lost to Athletics (44-45), 13-0 | American League Park I (16-22) | 37-51 | |
| » Starters: Snake Wiltse vs Dale Gear | Seventh | 19 out |
| » Major-league debuts: Tim Jordan (Senators) |
| Tuesday, August 13 |
| » Lost to Orioles (51-38), 5-1 | American League Park I (16-23) | 37-52 | Lost 2 |
| » Starters: Joe McGinnity vs Bill Carrick | Seventh | 19½ out |
| Wednesday, August 14 |
| » Defeated Orioles (51-39), 8-4 | American League Park I (17-23) | 38-52 | |
| » Starters: Jerry Nops vs Casey Patten | Seventh | 19 out |
| Friday, August 16 |
| » Lost to Tigers (50-45), 5-1 | American League Park I (17-24) | 38-53 | |
| » Starters: Joe Yeager vs Watty Lee | Seventh | 19 out |
| Saturday, August 17 |
| » Defeated Tigers (50-46), 5-1 | American League Park I (18-24) | 39-53 | |
| » Starters: Ed Siever vs Win Mercer | Seventh | 18½ out |
| » Lost to Tigers (51-46), 2-0 | American League Park I (18-25) | 39-54 | |
| » Starters: Roscoe Miller vs Casey Patten | Seventh | 18½ out |
| Monday, August 19 |
| » Defeated White Sox (60-39), 5-2 | American League Park I (19-25) | 40-54 | |
| » Starters: Roy Patterson vs Bill Carrick | Sixth | 17½ out |
| Tuesday, August 20 |
| » Lost to White Sox (61-39), 9-3 | American League Park I (19-26) | 40-55 | |
| » Starters: Clark Griffith vs Casey Patten | Seventh | 18½ out |
| Wednesday, August 21 |
| » Defeated White Sox (61-40), 8-0 | American League Park I (20-26) | 41-55 | |
| » Starters: Jack Katoll vs Win Mercer | Sixth | 17½ out |
| Thursday, August 22 |
| » Defeated Brewers (35-69), 4-3 | American League Park I (21-26) | 42-55 | Won 2 |
| » Starters: Bert Husting vs Watty Lee | Sixth | 17½ out |
| Saturday, August 24 |
| » Lost to Brewers (36-69), 1-0 | American League Park I (21-27) | 42-56 | |
| » Starters: Bill Reidy vs Bill Carrick | Sixth | 18 out |
| Sunday, August 25 |
| » Major-league debuts: Terry Turner (Pirates) |
| Monday, August 26 |
| » Defeated Indians (42-59), 8-1 | American League Park I (22-27) | 43-56 | |
| » Starters: Jack Bracken vs Win Mercer | Sixth | 18 out |
| Tuesday, August 27 |
| » Defeated Indians (42-60), 5-0 | American League Park I (23-27) | 44-56 | Won 2 |
| » Starters: Earl Moore vs Casey Patten | Sixth | 17 out |
| Wednesday, August 28 |
| » Defeated Indians (42-61), 4-1 | American League Park I (24-27) | 45-56 | Won 3 |
| » Starters: Pete Dowling vs Bill Carrick | Sixth | 17½ out |
| » Lost to Indians (43-61), 7-4 | American League Park I (24-28) | 45-57 | |
| » Starters: Harry McNeal vs Watty Lee | Sixth | 17½ out |
| Thursday, August 29 |
| » Defeated Indians (43-62), 13-11 | League Park I (2-3) | 46-57 | |
| » Starters: Watty Lee vs Jack Bracken | Sixth | 17 out |
| Saturday, August 31 |
| » Lost to Indians (44-62), 16-4 | League Park I (2-4) | 46-58 | |
| » Starters: Win Mercer vs Earl Moore | Sixth | 18 out |
| » Defeated Indians (44-63), 7-0 | League Park I (3-4) | 47-58 | |
| » Starters: Casey Patten vs Pete Dowling | Sixth | 18 out |
| Sunday, September 1 |
| » Defeated Tigers (56-52), 9-4 | Burns Park (1-0) | 48-58 | Won 2 |
| » Starters: Bill Carrick vs Ed Siever | Sixth | 18 out |
| Monday, September 2 |
| » Lost to Tigers (57-52), 5-2 | Bennett Park (4-3) | 48-59 | |
| » Starters: Casey Patten vs Jack Cronin | Sixth | 19 out |
| » Lost to Tigers (58-52), 7-4 | Bennett Park (4-4) | 48-60 | Lost 2 |
| » Starters: Dale Gear vs Roscoe Miller | Sixth | 19 out |
| Tuesday, September 3 |
| » Defeated Tigers (58-53), 4-2 | Bennett Park (5-4) | 49-60 | |
| » Starters: Win Mercer vs Joe Yeager | Sixth | 18 out |
| Wednesday, September 4 |
| » Lost to White Sox (70-44), 9-5 | South Side Park III (2-5) | 49-61 | |
| » Starters: Bill Carrick vs Jack Katoll | Sixth | 19 out |
| Thursday, September 5 |
| » Lost to White Sox (71-44), 4-3 | South Side Park III (2-6) | 49-62 | Lost 2 |
| » Starters: Bill Carrick vs Roy Patterson | Sixth | 19 out |
| » Defeated White Sox (71-45), 9-7 | South Side Park III (3-6) | 50-62 | |
| » Starters: Casey Patten vs Wiley Piatt | Sixth | 19 out |
| Friday, September 6 |
| » Defeated White Sox (71-46), 5-3 | South Side Park III (4-6) | 51-62 | Won 2 |
| » Starters: Win Mercer vs Jack Katoll | Sixth | 18 out |
| Saturday, September 7 |
| » Defeated Brewers (43-74), 20-8 | Lloyd Street Grounds (3-5) | 52-62 | Won 3 |
| » Starters: Watty Lee vs Tully Sparks | Sixth | 18 out |
| Sunday, September 8 |
| » Lost to Brewers (44-74), 6-4 | Lloyd Street Grounds (3-6) | 52-63 | |
| » Starters: Bill Carrick vs Bert Husting | Sixth | 18½ out |
| » Defeated Brewers (44-75), 7-4 | Lloyd Street Grounds (4-6) | 53-63 | |
| » Starters: Casey Patten vs Bill Reidy | Sixth | 18½ out |
| Tuesday, September 10 |
| » Major-league debuts: Jim McGuire (Indians) |
| Wednesday, September 11 |
| » Lost to Red Sox (68-52), 9-0 | American League Park I (24-29) | 53-64 | |
| » Starters: Cy Young vs Win Mercer | Sixth | 20½ out |
| Thursday, September 12 |
| » Tied Red Sox, 6-6 | American League Park I (24-29) | 53-64 | |
| » Starters: Ted Lewis vs Casey Patten | Sixth | 20½ out |
| Friday, September 13 |
| » Lost to Red Sox (69-52), 5-1 | American League Park I (24-30) | 53-65 | Lost 2 |
| » Starters: George Winter vs Bill Carrick | Sixth | 20 out |
| » Defeated Red Sox (69-53), 5-3 | American League Park I (25-30) | 54-65 | |
| » Starters: Fred Mitchell vs Watty Lee | Sixth | 20 out |
| Saturday, September 14 |
| » Lost to Red Sox (70-53), 12-1 | Huntington Ave Baseball Grounds (4-4) | 54-66 | |
| » Starters: Win Mercer vs Cy Young | Sixth | 20½ out |
| Sunday, September 15 |
| » Major-league debuts: Lou Gertenrich (Brewers) |
| Monday, September 16 |
| » Lost to Red Sox (71-53), 6-5 | Huntington Ave Baseball Grounds (4-5) | 54-67 | Lost 2 |
| » Starters: Casey Patten vs Ted Lewis | Sixth | 21½ out |
| » Defeated Red Sox (71-54), 7-5 | Huntington Ave Baseball Grounds (5-5) | 55-67 | |
| » Starters: Bill Carrick vs George Winter | Sixth | 21½ out |
| Wednesday, September 18 |
| » Lost to Brewers (47-79), 9-2 | American League Park I (25-31) | 55-68 | |
| » Starters: Ned Garvin vs Watty Lee | Sixth | 22½ out |
| » Defeated Brewers (47-80), 5-3 | American League Park I (26-31) | 56-68 | |
| » Starters: Bert Husting vs Win Mercer | Sixth | 22½ out |
| Friday, September 20 |
| » Defeated Indians (52-74), 9-8 | American League Park I (27-31) | 57-68 | Won 2 |
| » Starters: Bill Cristall vs Bill Carrick | Sixth | 22½ out |
| Saturday, September 21 |
| » Defeated Indians (52-75), 18-7 | American League Park I (28-31) | 58-68 | Won 3 |
| » Starters: Harry McNeal vs Casey Patten | Sixth | 21 out |
| » Defeated Indians (52-76), 11-3 | American League Park I (29-31) | 59-68 | Won 4 |
| » Starters: Earl Moore vs Dale Gear | Sixth | 21 out |
| Monday, September 23 |
| » Lost to Indians (53-76), 6-3 | American League Park I (29-32) | 59-69 | |
| » Starters: Jack Bracken vs Watty Lee | Sixth | 21½ out |
| » Lost to Indians (54-76), 7-3 | American League Park I (29-33) | 59-70 | Lost 2 |
| » Starters: Pete Dowling vs Win Mercer | Sixth | 21½ out |
| Tuesday, September 24 |
| » Defeated Tigers (70-59), 4-1 | American League Park I (30-33) | 60-70 | |
| » Starters: Jack Cronin vs Bill Carrick | Sixth | 20½ out |
| Wednesday, September 25 |
| » Defeated Tigers (70-60), 3-2 | American League Park I (31-33) | 61-70 | Won 2 |
| » Starters: Roscoe Miller vs Casey Patten | Sixth | 19½ out |
| Thursday, September 26 |
| » Lost to Tigers (71-60), 5-3 | American League Park I (31-34) | 61-71 | |
| » Starters: Joe Yeager vs Win Mercer | Sixth | 19½ out |
| Friday, September 27 |
| » Lost to White Sox (83-53), 6-4 | American League Park I (31-35) | 61-72 | Lost 2 |
| » Starters: Wiley Piatt vs Bill Carrick | Sixth | 20½ out |
| Saturday, October 5 |
| » Major-league debuts: Germany Schaefer (Cubs) |
| Friday, November 22 |
| Future Senator Harry Rice is born in Ware Station, IL. |
| Tuesday, December 3 |
| Future Senator Bennie Tate is born in Whitwell, TN. |
Game information provided by Retrosheet (www.retrosheet.org) |