| Saturday, January 5 |
| Future Indian Luke Sewell is born in Titus, AL. |
| Tuesday, February 12 |
| Future Indian Virgil Cheeves is born in Oklahoma City, OK. |
| Sunday, February 17 |
| Future Indian Eddie Phillips is born in Worcester, MA. |
| Thursday, April 18 |
| » Major-league debuts: Lefty Davis (Dodgers) |
| Friday, April 19 |
| » Major-league debuts: Jim Delahanty (Cubs) |
| Saturday, April 20 |
| » Major-league debuts: John Dobbs (Reds) |
| Future Indian Frank Wilson is born in Malden, MA. |
| Monday, April 22 |
| » Major-league debuts: Doc White (Phillies) |
| Wednesday, April 24 |
| » Lost to White Sox (1-0), 8-2 | South Side Park III (0-1) | 0-1 | |
| » Starters: Bill Hoffer vs Roy Patterson | Third | 1 out |
| » Major-league debuts: Dave Brain (White Sox) |
| Thursday, April 25 |
| » Lost to White Sox (2-0), 7-3 | South Side Park III (0-2) | 0-2 | Lost 2 |
| » Starters: Earl Moore vs John Skopec | Fifth | 2 out |
| Saturday, April 27 |
| » Defeated White Sox (2-1), 10-4 | South Side Park III (1-2) | 1-2 | |
| » Starters: Bill Hart vs Jack Katoll | Fourth | 2 out |
| Sunday, April 28 |
| » Lost to White Sox (3-1), 13-1 | South Side Park III (1-3) | 1-3 | |
| » Starters: Bock Baker vs Clark Griffith | Fourth | 3 out |
| Monday, April 29 |
| » Defeated Brewers (0-5), 4-3 | League Park I (1-0) | 2-3 | |
| » Starters: Pink Hawley vs Bill Hoffer | Fifth | 3 out |
| Tuesday, April 30 |
| » Lost to Brewers (1-5), 8-6 | League Park I (1-1) | 2-4 | |
| » Starters: Ned Garvin vs Ed Scott | Fifth | 3 out |
| » Major-league debuts: Danny Shay (Indians) |
| Wednesday, May 1 |
| » Defeated Brewers (1-6), 6-3 | League Park I (2-1) | 3-4 | |
| » Starters: Bill Reidy vs Earl Moore | Fourth | 2 out |
| Thursday, May 2 |
| » Lost to Brewers (2-6), 9-7 | League Park I (2-2) | 3-5 | |
| » Starters: Bert Husting vs Bill Hart | Fourth | 3 out |
| Friday, May 3 |
| » Lost to Tigers (7-2), 6-3 | Bennett Park (0-1) | 3-6 | Lost 2 |
| » Starters: Bill Hoffer vs Ed Siever | Sixth | 4 out |
| Saturday, May 4 |
| » Defeated Tigers (7-3), 11-4 | Bennett Park (1-1) | 4-6 | |
| » Starters: Earl Moore vs Jack Cronin | Third | 3 out |
| Sunday, May 5 |
| » Lost to Tigers (8-3), 10-3 | Burns Park (0-1) | 4-7 | |
| » Starters: Ed Scott vs Ed Siever | Fifth | 4 out |
| Monday, May 6 |
| » Lost to Tigers (9-3), 5-4 | Bennett Park (1-2) | 4-8 | Lost 2 |
| » Starters: Bill Hart vs Joe Yeager | Fifth | 5 out |
| Wednesday, May 8 |
| » Lost to White Sox (9-4), 3-1 | League Park I (2-3) | 4-9 | Lost 3 |
| » Starters: John Skopec vs Bill Hoffer | Seventh | 6 out |
| Thursday, May 9 |
| » Lost to White Sox (10-4), 4-2 | League Park I (2-4) | 4-10 | Lost 4 |
| » Starters: Jack Katoll vs Earl Moore | Sixth | 6 out |
| Friday, May 10 |
| » Lost to White Sox (11-4), 5-4 | League Park I (2-5) | 4-11 | Lost 5 |
| » Starters: Roy Patterson vs Bill Hart | Sixth | 7 out |
| Saturday, May 11 |
| » Lost to Brewers (5-11), 12-5 | Lloyd Street Grounds (0-1) | 4-12 | Lost 6 |
| » Starters: Ed Scott vs Tully Sparks | Eighth | 8 out |
| Sunday, May 12 |
| » Lost to Brewers (6-11), 5-2 | Lloyd Street Grounds (0-2) | 4-13 | Lost 7 |
| » Starters: Bill Hart vs Pete Dowling | Eighth | 9 out |
| Monday, May 13 |
| » Lost to Brewers (7-11), 5-4 | Lloyd Street Grounds (0-3) | 4-14 | Lost 8 |
| » Starters: Ed Scott vs Pink Hawley | Eighth | 10 out |
| Tuesday, May 14 |
| » Lost to Brewers (8-11), 11-1 | Lloyd Street Grounds (0-4) | 4-15 | Lost 9 |
| » Starters: Bill Hart vs Bill Reidy | Eighth | 10 out |
| Thursday, May 16 |
| » Lost to Tigers (15-5), 5-2 | League Park I (2-6) | 4-16 | Lost 10 |
| » Starters: Joe Yeager vs Dick Braggins | Eighth | 11 out |
| Friday, May 17 |
| » Lost to Tigers (16-5), 6-4 | League Park I (2-7) | 4-17 | Lost 11 |
| » Starters: Jack Cronin vs Bill Hoffer | Seventh | 12 out |
| Saturday, May 18 |
| » Defeated Tigers (16-6), 9-7 | League Park I (3-7) | 5-17 | |
| » Starters: Roscoe Miller vs Ed Scott | Eighth | 11 out |
| Sunday, May 19 |
| » Defeated Tigers (16-7), 11-2 | Burns Park (1-1) | 6-17 | Won 2 |
| » Starters: Earl Moore vs Ed Siever | Seventh | 10 out |
| Monday, May 20 |
| » Lost to Tigers (17-7), 13-1 | League Park I (3-8) | 6-18 | |
| » Starters: Emil Frisk vs Bill Hart | Eighth | 11 out |
| » Major-league debuts: Frank Cross (Indians) |
| Wednesday, May 22 |
| » Defeated Senators (12-8), 6-5 | League Park I (4-8) | 7-18 | |
| » Starters: Win Mercer vs Dick Braggins | Eighth | 10 out |
| Thursday, May 23 |
| » Defeated Senators (12-9), 14-13 | League Park I (5-8) | 8-18 | Won 2 |
| » Starters: Casey Patten vs Bill Hoffer | Eighth | 9½ out |
| Friday, May 24 |
| » Tied Senators, 5-5 | League Park I (5-8) | 8-18 | |
| » Starters: Dale Gear vs Ed Scott | Eighth | 9½ out |
| Saturday, May 25 |
| » Lost to Red Sox (11-11), 5-0 | League Park I (5-9) | 8-19 | |
| » Starters: Ted Lewis vs Earl Moore | Eighth | 10½ out |
| Thursday, May 30 |
| » Lost to Athletics (11-17), 3-1 | League Park I (5-10) | 8-20 | Lost 2 |
| » Starters: Eddie Plank vs Bill Hart | Eighth | 13½ out |
| » Lost to Athletics (12-17), 8-2 | League Park I (5-11) | 8-21 | Lost 3 |
| » Starters: Bill Bernhard vs Ed Scott | Eighth | 13½ out |
| Friday, May 31 |
| » Lost to Athletics (13-17), 15-14 | League Park I (5-12) | 8-22 | Lost 4 |
| » Starters: Chick Fraser vs Earl Moore | Eighth | 14½ out |
| Saturday, June 1 |
| » Lost to Athletics (14-17), 6-2 | League Park I (5-13) | 8-23 | Lost 5 |
| » Starters: Wiley Piatt vs Bill Hoffer | Eighth | 14½ out |
| Monday, June 3 |
| » Lost to Orioles (15-11), 7-2 | League Park I (5-14) | 8-24 | Lost 6 |
| » Starters: Jack Dunn vs Pete Dowling | Eighth | 14 out |
| Tuesday, June 4 |
| » Defeated Orioles (15-12), 5-1 | League Park I (6-14) | 9-24 | |
| » Starters: Crazy Schmit vs Bill Hart | Eighth | 14 out |
| Thursday, June 6 |
| » Defeated Orioles (15-13), 4-2 | League Park I (7-14) | 10-24 | Won 2 |
| » Starters: Jack Dunn vs Pete Dowling | Eighth | 13½ out |
| » Major-league debuts: Burt Hart (Orioles) |
| Friday, June 7 |
| » Lost to Orioles (16-13), 10-9 | Oriole Park IV (0-1) | 10-25 | |
| » Starters: Earl Moore vs Joe McGinnity | Eighth | 14½ out |
| Saturday, June 8 |
| » Defeated Orioles (16-14), 13-5 | Oriole Park IV (1-1) | 11-25 | |
| » Starters: Ed Scott vs Crazy Schmit | Eighth | 13½ out |
| Monday, June 10 |
| » Defeated Orioles (16-15), 13-6 | Oriole Park IV (2-1) | 12-25 | Won 2 |
| » Starters: Pete Dowling vs Joe McGinnity | Eighth | 13½ out |
| Tuesday, June 11 |
| » Defeated Orioles (16-16), 8-5 | Oriole Park IV (3-1) | 13-25 | Won 3 |
| » Starters: Bill Hart vs Harry Howell | Eighth | 12½ out |
| Wednesday, June 12 |
| » Defeated Senators (19-15), 6-0 | American League Park I (1-0) | 14-25 | Won 4 |
| » Starters: Earl Moore vs Bill Carrick | Eighth | 11½ out |
| Saturday, June 15 |
| » Defeated Senators (19-16), 5-3 | American League Park I (2-0) | 15-25 | Won 5 |
| » Starters: Ed Scott vs Dale Gear | Seventh | 12 out |
| Monday, June 17 |
| » Lost to Athletics (20-22), 12-8 | Columbia Park (0-1) | 15-26 | |
| » Starters: Bill Hoffer vs Wiley Piatt | Eighth | 11½ out |
| Tuesday, June 18 |
| » Defeated Athletics (20-23), 9-5 | Columbia Park (1-1) | 16-26 | |
| » Starters: Pete Dowling vs Eddie Plank | Seventh | 10½ out |
| Wednesday, June 19 |
| » Lost to Athletics (21-23), 4-3 | Columbia Park (1-2) | 16-27 | |
| » Starters: Bill Hart vs Chick Fraser | Seventh | 10½ out |
| Thursday, June 20 |
| » Defeated Athletics (21-24), 6-4 | Columbia Park (2-2) | 17-27 | |
| » Starters: Ed Scott vs Bill Bernhard | Seventh | 9½ out |
| Friday, June 21 |
| » Lost to Red Sox (27-17), 4-3 | Huntington Ave Baseball Grounds (0-1) | 17-28 | |
| » Starters: Pete Dowling vs Ted Lewis | Sixth | 10½ out |
| Saturday, June 22 |
| » Lost to Red Sox (28-17), 8-1 | Huntington Ave Baseball Grounds (0-2) | 17-29 | Lost 2 |
| » Starters: Bill Hart vs George Winter | Sixth | 11½ out |
| Monday, June 24 |
| » Defeated Red Sox (28-18), 7-1 | Huntington Ave Baseball Grounds (1-2) | 18-29 | |
| » Starters: Earl Moore vs Fred Mitchell | Seventh | 11½ out |
| Tuesday, June 25 |
| » Lost to Red Sox (29-18), 4-2 | Huntington Ave Baseball Grounds (1-3) | 18-30 | |
| » Starters: Pete Dowling vs Cy Young | Seventh | 12½ out |
| Wednesday, June 26 |
| » Lost to Brewers (19-32), 8-5 | League Park I (7-15) | 18-31 | Lost 2 |
| » Starters: Bill Reidy vs Dick Braggins | Eighth | 13 out |
| Thursday, June 27 |
| » Lost to White Sox (34-20), 5-1 | South Side Park III (1-4) | 18-32 | Lost 3 |
| » Starters: Bill Hoffer vs Jack Katoll | Eighth | 14 out |
| Friday, June 28 |
| » Lost to White Sox (35-20), 7-6 | South Side Park III (1-5) | 18-33 | Lost 4 |
| » Starters: Bill Hart vs Roy Patterson | Eighth | 15 out |
| Saturday, June 29 |
| » Lost to White Sox (36-20), 4-1 | South Side Park III (1-6) | 18-34 | Lost 5 |
| » Starters: Earl Moore vs Zaza Harvey | Eighth | 16 out |
| Sunday, June 30 |
| » Defeated Brewers (19-36), 7-0 | Lloyd Street Grounds (1-4) | 19-34 | |
| » Starters: Pete Dowling vs Bill Reidy | Seventh | 16 out |
| Monday, July 1 |
| » Defeated Brewers (19-37), 8-5 | Lloyd Street Grounds (2-4) | 20-34 | Won 2 |
| » Starters: Bill Hart vs Tully Sparks | Seventh | 15½ out |
| Tuesday, July 2 |
| » Defeated Brewers (19-38), 6-4 | Lloyd Street Grounds (3-4) | 21-34 | Won 3 |
| » Starters: Earl Moore vs Pink Hawley | Seventh | 15½ out |
| Wednesday, July 3 |
| » Lost to White Sox (39-20), 4-3 | League Park I (7-16) | 21-35 | |
| » Starters: Jack Katoll vs Pete Dowling | Seventh | 16½ out |
| Thursday, July 4 |
| » Defeated White Sox (39-21), 8-2 | League Park I (8-16) | 22-35 | |
| » Starters: Roy Patterson vs Bill Hart | Seventh | 14½ out |
| » Defeated White Sox (39-22), 6-5 | League Park I (9-16) | 23-35 | Won 2 |
| » Starters: Zaza Harvey vs Bill Hoffer | Seventh | 14½ out |
| Friday, July 5 |
| » Lost to Brewers (21-40), 6-2 | League Park I (9-17) | 23-36 | |
| » Starters: Bert Husting vs Earl Moore | Seventh | 15½ out |
| Saturday, July 6 |
| » Defeated Brewers (21-41), 11-6 | League Park I (10-17) | 24-36 | |
| » Starters: Pink Hawley vs Pete Dowling | Seventh | 14½ out |
| Sunday, July 7 |
| » Lost to Brewers (22-41), 2-0 | Lloyd Street Grounds (3-5) | 24-37 | |
| » Starters: Ed Scott vs Bill Reidy | Seventh | 15 out |
| Tuesday, July 9 |
| » Lost to Tigers (34-29), 11-1 | League Park I (10-18) | 24-38 | Lost 2 |
| » Starters: Ed Siever vs Bill Hart | Seventh | 16 out |
| Wednesday, July 10 |
| » Lost to Tigers (35-29), 7-4 | League Park I (10-19) | 24-39 | Lost 3 |
| » Starters: Roscoe Miller vs Pete Dowling | Seventh | 16 out |
| Thursday, July 11 |
| » Defeated Tigers (35-30), 6-1 | League Park I (11-19) | 25-39 | |
| » Starters: Jack Cronin vs Earl Moore | Seventh | 16 out |
| Friday, July 12 |
| » Defeated Tigers (35-31), 5-2 | Bennett Park (2-2) | 26-39 | Won 2 |
| » Starters: Ed Scott vs Ed Siever | Seventh | 16 out |
| Saturday, July 13 |
| » Lost to Tigers (36-31), 19-12 | Bennett Park (2-3) | 26-40 | |
| » Starters: Gus Weyhing vs Roscoe Miller | Seventh | 16 out |
| Sunday, July 14 |
| » Lost to Tigers (37-31), 5-0 | Burns Park (1-2) | 26-41 | Lost 2 |
| » Starters: Pete Dowling vs Joe Yeager | Seventh | 16½ out |
| Tuesday, July 16 |
| » Lost to Red Sox (41-23), 10-8 | League Park I (11-20) | 26-42 | Lost 3 |
| » Starters: Cy Young vs Earl Moore | Seventh | 18 out |
| Wednesday, July 17 |
| » Lost to Red Sox (42-23), 9-3 | League Park I (11-21) | 26-43 | Lost 4 |
| » Starters: Ted Lewis vs Ed Scott | Seventh | 19 out |
| » Lost to Red Sox (43-23), 10-2 | League Park I (11-22) | 26-44 | Lost 5 |
| » Starters: Nig Cuppy vs Pete Dowling | Seventh | 19 out |
| Thursday, July 18 |
| » Defeated Red Sox (43-24), 6-5 | League Park I (12-22) | 27-44 | |
| » Starters: George Winter vs Bill Hart | Seventh | 19½ out |
| Friday, July 19 |
| » Defeated Red Sox (43-25), 2-1 | League Park I (13-22) | 28-44 | Won 2 |
| » Starters: Cy Young vs Earl Moore | Seventh | 18½ out |
| Saturday, July 20 |
| » Lost to Senators (31-33), 9-7 | League Park I (13-23) | 28-45 | |
| » Starters: Casey Patten vs Ed Scott | Seventh | 18½ out |
| Monday, July 22 |
| » Defeated Senators (31-34), 6-3 | League Park I (14-23) | 29-45 | |
| » Starters: Watty Lee vs Bill Hart | Seventh | 18 out |
| Tuesday, July 23 |
| » Tied Senators, 4-4 | League Park I (14-23) | 29-45 | |
| » Starters: Bill Carrick vs Ed Scott | Seventh | 18½ out |
| Wednesday, July 24 |
| » Lost to Orioles (39-29), 9-6 | League Park I (14-24) | 29-46 | |
| » Starters: Joe McGinnity vs Earl Moore | Seventh | 19½ out |
| Thursday, July 25 |
| » Lost to Orioles (40-29), 5-1 | League Park I (14-25) | 29-47 | Lost 2 |
| » Starters: Jerry Nops vs Pete Dowling | Seventh | 20½ out |
| Friday, July 26 |
| » Lost to Orioles (41-29), 6-1 | League Park I (14-26) | 29-48 | Lost 3 |
| » Starters: Frank Foreman vs Bill Hart | Seventh | 21½ out |
| Saturday, July 27 |
| » Defeated Athletics (32-42), 4-3 | League Park I (15-26) | 30-48 | |
| » Starters: Chick Fraser vs Ed Scott | Seventh | 21½ out |
| Tuesday, July 30 |
| » Lost to Athletics (33-42), 11-5 | League Park I (15-27) | 30-49 | |
| » Starters: Eddie Plank vs Earl Moore | Seventh | 21½ out |
| Friday, August 2 |
| » Defeated Brewers (30-55), 7-0 | Lloyd Street Grounds (4-5) | 31-49 | |
| » Starters: Pete Dowling vs Bert Husting | Seventh | 22½ out |
| Saturday, August 3 |
| » Defeated Brewers (30-56), 8-7 | Lloyd Street Grounds (5-5) | 32-49 | Won 2 |
| » Starters: Earl Moore vs Tully Sparks | Seventh | 21½ out |
| Sunday, August 4 |
| » Lost to White Sox (57-30), 9-5 | South Side Park III (1-7) | 32-50 | |
| » Starters: Pete Dowling vs Clark Griffith | Seventh | 22½ out |
| Monday, August 5 |
| » Defeated White Sox (57-31), 6-3 | South Side Park III (2-7) | 33-50 | |
| » Starters: Harry McNeal vs Roy Patterson | Seventh | 21½ out |
| Wednesday, August 7 |
| » Defeated Brewers (33-58), 5-4 | League Park I (16-27) | 34-50 | Won 2 |
| » Starters: Bill Reidy vs Jack Bracken | Seventh | 20½ out |
| Thursday, August 8 |
| » Defeated Brewers (33-59), 5-3 | League Park I (17-27) | 35-50 | Won 3 |
| » Starters: Ned Garvin vs Pete Dowling | Seventh | 20½ out |
| Friday, August 9 |
| » Defeated Brewers (33-60), 8-3 | League Park I (18-27) | 36-50 | Won 4 |
| » Starters: Pink Hawley vs Earl Moore | Sixth | 19½ out |
| Saturday, August 10 |
| » Defeated White Sox (58-34), 11-7 | League Park I (19-27) | 37-50 | Won 5 |
| » Starters: Jack Katoll vs Harry McNeal | Sixth | 18½ out |
| Sunday, August 11 |
| » Defeated White Sox (58-35), 4-3 | South Side Park III (3-7) | 38-50 | Won 6 |
| » Starters: Jack Bracken vs Nixey Callahan | Sixth | 17½ out |
| Monday, August 12 |
| » Lost to White Sox (59-35), 17-2 | League Park I (19-28) | 38-51 | |
| » Starters: Clark Griffith vs Pete Dowling | Sixth | 18½ out |
| Tuesday, August 13 |
| » Defeated White Sox (59-36), 4-0 | League Park I (20-28) | 39-51 | |
| » Starters: Jack Katoll vs Earl Moore | Sixth | 18½ out |
| » Lost to White Sox (60-36), 14-1 | League Park I (20-29) | 39-52 | |
| » Starters: Roy Patterson vs Harry McNeal | Sixth | 18½ out |
| Thursday, August 15 |
| » Defeated Orioles (51-40), 9-5 | Oriole Park IV (4-1) | 40-52 | |
| » Starters: Jack Bracken vs Harry Howell | Sixth | 18 out |
| Friday, August 16 |
| » Lost to Orioles (52-40), 1-0 | Oriole Park IV (4-2) | 40-53 | |
| » Starters: Pete Dowling vs Frank Foreman | Sixth | 18 out |
| Saturday, August 17 |
| » Lost to Orioles (53-40), 3-2 | Oriole Park IV (4-3) | 40-54 | Lost 2 |
| » Starters: Earl Moore vs Joe McGinnity | Sixth | 18 out |
| Tuesday, August 20 |
| » Defeated Athletics (50-49), 7-3 | Columbia Park (3-2) | 41-54 | |
| » Starters: Harry McNeal vs Bill Bernhard | Sixth | 17½ out |
| Wednesday, August 21 |
| » Lost to Athletics (51-49), 8-7 | Columbia Park (3-3) | 41-55 | |
| » Starters: Jack Bracken vs Chick Fraser | Seventh | 18 out |
| » Lost to Athletics (52-49), 7-3 | Columbia Park (3-4) | 41-56 | Lost 2 |
| » Starters: Pete Dowling vs Snake Wiltse | Seventh | 18 out |
| Thursday, August 22 |
| » Lost to Red Sox (61-40), 4-3 | Huntington Ave Baseball Grounds (1-4) | 41-57 | Lost 3 |
| » Starters: Earl Moore vs George Winter | Seventh | 19 out |
| Friday, August 23 |
| » Lost to Red Sox (62-40), 5-1 | Huntington Ave Baseball Grounds (1-5) | 41-58 | Lost 4 |
| » Starters: Harry McNeal vs Cy Young | Seventh | 20 out |
| Saturday, August 24 |
| » Defeated Red Sox (62-41), 4-2 | Huntington Ave Baseball Grounds (2-5) | 42-58 | |
| » Starters: Pete Dowling vs Ted Lewis | Seventh | 19 out |
| Sunday, August 25 |
| » Major-league debuts: Terry Turner (Pirates) |
| Monday, August 26 |
| » Lost to Senators (43-56), 8-1 | American League Park I (2-1) | 42-59 | |
| » Starters: Jack Bracken vs Win Mercer | Seventh | 20 out |
| Tuesday, August 27 |
| » Lost to Senators (44-56), 5-0 | American League Park I (2-2) | 42-60 | Lost 2 |
| » Starters: Earl Moore vs Casey Patten | Seventh | 20 out |
| Wednesday, August 28 |
| » Lost to Senators (45-56), 4-1 | American League Park I (2-3) | 42-61 | Lost 3 |
| » Starters: Pete Dowling vs Bill Carrick | Seventh | 20½ out |
| » Defeated Senators (45-57), 7-4 | American League Park I (3-3) | 43-61 | |
| » Starters: Harry McNeal vs Watty Lee | Seventh | 20½ out |
| Thursday, August 29 |
| » Lost to Senators (46-57), 13-11 | League Park I (20-30) | 43-62 | |
| » Starters: Watty Lee vs Jack Bracken | Seventh | 21 out |
| Saturday, August 31 |
| » Defeated Senators (46-58), 16-4 | League Park I (21-30) | 44-62 | |
| » Starters: Win Mercer vs Earl Moore | Seventh | 22 out |
| » Lost to Senators (47-58), 7-0 | League Park I (21-31) | 44-63 | |
| » Starters: Casey Patten vs Pete Dowling | Seventh | 22 out |
| Monday, September 2 |
| » Lost to Red Sox (65-45), 9-4 | League Park I (21-32) | 44-64 | Lost 2 |
| » Starters: George Winter vs Pete Dowling | Seventh | 23½ out |
| » Lost to Red Sox (66-45), 4-1 | League Park I (21-33) | 44-65 | Lost 3 |
| » Starters: Cy Young vs Jack Bracken | Seventh | 23½ out |
| » Major-league debuts: Paddy Livingston (Indians) |
| Tuesday, September 3 |
| » Defeated Red Sox (66-46), 1-0 | League Park I (22-33) | 45-65 | |
| » Starters: Ted Lewis vs Earl Moore | Seventh | 22 out |
| » Defeated Red Sox (66-47), 4-0 | League Park I (23-33) | 46-65 | Won 2 |
| » Starters: Fred Mitchell vs Bill Cristall | Seventh | 22 out |
| Wednesday, September 4 |
| » Defeated Orioles (57-51), 5-4 | League Park I (24-33) | 47-65 | Won 3 |
| » Starters: Jerry Nops vs Harry McNeal | Seventh | 22 out |
| Thursday, September 5 |
| » Defeated Orioles (57-52), 3-1 | League Park I (25-33) | 48-65 | Won 4 |
| » Starters: Joe McGinnity vs Pete Dowling | Seventh | 21½ out |
| Friday, September 6 |
| » Defeated Orioles (57-53), 10-7 | League Park I (26-33) | 49-65 | Won 5 |
| » Starters: Frank Foreman vs Earl Moore | Seventh | 21 out |
| » Lost to Orioles (58-53), 7-4 | League Park I (26-34) | 49-66 | |
| » Starters: Harry Howell vs Jack Bracken | Seventh | 21 out |
| Saturday, September 7 |
| » Lost to Athletics (61-56), 7-4 | League Park I (26-35) | 49-67 | Lost 2 |
| » Starters: Eddie Plank vs Bill Cristall | Seventh | 22 out |
| Monday, September 9 |
| » Defeated Athletics (61-57), 4-1 | League Park I (27-35) | 50-67 | |
| » Starters: Bill Bernhard vs Pete Dowling | Seventh | 23 out |
| Tuesday, September 10 |
| » Defeated Athletics (61-58), 7-0 | League Park I (28-35) | 51-67 | Won 2 |
| » Starters: Snake Wiltse vs Earl Moore | Seventh | 23½ out |
| » Lost to Athletics (62-58), 4-1 | League Park I (28-36) | 51-68 | |
| » Starters: Chick Fraser vs Jack Bracken | Seventh | 23½ out |
| » Major-league debuts: Jim McGuire (Indians) |
| Thursday, September 12 |
| » Lost to Tigers (64-55), 5-4 | League Park I (28-37) | 51-69 | Lost 2 |
| » Starters: Roscoe Miller vs Bill Cristall | Seventh | 24½ out |
| » Lost to Tigers (65-55), 4-3 | League Park I (28-38) | 51-70 | Lost 3 |
| » Starters: Ed Siever vs Harry McNeal | Seventh | 24½ out |
| Friday, September 13 |
| » Lost to Tigers (66-55), 7-0 | League Park I (28-39) | 51-71 | Lost 4 |
| » Starters: Jack Cronin vs Pete Dowling | Seventh | 24½ out |
| Saturday, September 14 |
| » Defeated Tigers (66-56), 5-3 | Bennett Park (3-3) | 52-71 | |
| » Starters: Earl Moore vs Joe Yeager | Seventh | 24 out |
| Sunday, September 15 |
| » Lost to Tigers (67-56), 21-0 | Burns Park (1-3) | 52-72 | |
| » Starters: Jack Bracken vs Ed Siever | Seventh | 25½ out |
| Tuesday, September 17 |
| » Lost to Red Sox (72-54), 5-0 | Huntington Ave Baseball Grounds (2-6) | 52-73 | Lost 2 |
| » Starters: Pete Dowling vs Cy Young | Seventh | 26 out |
| Friday, September 20 |
| » Lost to Senators (57-68), 9-8 | American League Park I (3-4) | 52-74 | Lost 3 |
| » Starters: Bill Cristall vs Bill Carrick | Seventh | 28 out |
| Saturday, September 21 |
| » Lost to Senators (58-68), 18-7 | American League Park I (3-5) | 52-75 | Lost 4 |
| » Starters: Harry McNeal vs Casey Patten | Seventh | 28½ out |
| » Lost to Senators (59-68), 11-3 | American League Park I (3-6) | 52-76 | Lost 5 |
| » Starters: Earl Moore vs Dale Gear | Seventh | 28½ out |
| Monday, September 23 |
| » Defeated Senators (59-69), 6-3 | American League Park I (4-6) | 53-76 | |
| » Starters: Jack Bracken vs Watty Lee | Seventh | 27 out |
| » Defeated Senators (59-70), 7-3 | American League Park I (5-6) | 54-76 | Won 2 |
| » Starters: Pete Dowling vs Win Mercer | Seventh | 27 out |
| Tuesday, September 24 |
| » Lost to Orioles (65-62), 11-6 | Oriole Park IV (4-4) | 54-77 | |
| » Starters: Bill Cristall vs Harry Howell | Seventh | 27 out |
| Wednesday, September 25 |
| » Lost to Orioles (66-62), 8-5 | Oriole Park IV (4-5) | 54-78 | Lost 2 |
| » Starters: Pete Dowling vs Joe McGinnity | Seventh | 27 out |
| Thursday, September 26 |
| » Lost to Orioles (67-62), 10-9 | Oriole Park IV (4-6) | 54-79 | Lost 3 |
| » Starters: Harry McNeal vs Bill Karns | Seventh | 27 out |
| Friday, September 27 |
| » Lost to Athletics (72-62), 14-6 | Columbia Park (3-5) | 54-80 | Lost 4 |
| » Starters: Jack Bracken vs Snake Wiltse | Seventh | 28 out |
| Saturday, September 28 |
| » Lost to Athletics (73-62), 12-9 | Columbia Park (3-6) | 54-81 | Lost 5 |
| » Starters: Bill Cristall vs Bill Bernhard | Seventh | 29 out |
| » Lost to Athletics (74-62), 3-1 | Columbia Park (3-7) | 54-82 | Lost 6 |
| » Starters: Pete Dowling vs Snake Wiltse | Seventh | 29 out |
| Saturday, October 5 |
| » Major-league debuts: Germany Schaefer (Cubs) |
| Monday, December 30 |
| Future Indian Dick Porter is born in Princess Anne, MD. |
Game information provided by Retrosheet (www.retrosheet.org) |