| SCOREBOARD: SEPTEMBER 2, 1910 |
| Brooklyn Dodgers 3, Boston Braves 2 at South End Grounds III |
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| Brooklyn Dodgers 8, Boston Braves 0 at South End Grounds III |
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| Cincinnati Reds 3, Pittsburgh Pirates 2 at Palace of the Fans |
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| Philadelphia Phillies 3, New York Giants 2 at Baker Bowl |
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| Philadelphia Phillies 5, New York Giants 4 at Baker Bowl |
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| Cleveland Indians 6, St. Louis Browns 5 at League Park II |
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| Detroit Tigers 7, Chicago White Sox 3 at Bennett Park |
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| New York Yankees 6, Boston Red Sox 5 at Hilltop Park |
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| Philadelphia Athletics 5, Washington Senators 1 at American League Park II |
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| Philadelphia Athletics 2, Washington Senators 1 at American League Park II |
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| Compiled by Retrosheet (www.retrosheet.org) |
IN THE NEWS: Jack Coombs begins a streak of 53 shutout innings, topping Doc White's 46 of 1904. Three years later Walter Johnson will top Coombs.
| SCOREBOARD: SEPTEMBER 5, 1910 |
| Brooklyn Dodgers 5, New York Giants 1 at Washington Park III |
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| Brooklyn Dodgers 3, New York Giants 2 at Washington Park III |
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| Cincinnati Reds 4, Chicago Cubs 3 at Palace of the Fans |
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| Chicago Cubs 9, Cincinnati Reds 5 at Palace of the Fans |
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| Philadelphia Phillies 6, Boston Braves 3 at Baker Bowl |
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| Philadelphia Phillies 13, Boston Braves 0 at Baker Bowl |
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| Pittsburgh Pirates 9, St. Louis Cardinals 8 at Forbes Field |
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| Pittsburgh Pirates 11, St. Louis Cardinals 4 at Forbes Field |
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| Washington Senators 4, Boston Red Sox 1 at Huntington Ave Baseball Grounds |
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| Boston Red Sox 5, Washington Senators 0 at Huntington Ave Baseball Grounds |
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| Cleveland Indians 5, Chicago White Sox 0 at Comiskey Park I |
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| Chicago White Sox 10, Cleveland Indians 5 at Comiskey Park I |
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| Detroit Tigers 4, St. Louis Browns 1 at Bennett Park |
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| Detroit Tigers 4, St. Louis Browns 3 at Bennett Park |
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| New York Yankees 5, Philadelphia Athletics 2 at Hilltop Park |
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| Philadelphia Athletics 2, New York Yankees 1 at Hilltop Park |
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| Compiled by Retrosheet (www.retrosheet.org) |
IN THE NEWS: At the Polo Grounds, Christy Mathewson allows seven hits in beating the Boston doves, 2–0. Sam Frock is hung with the loss.
| SCOREBOARD: SEPTEMBER 8, 1910 |
| Chicago Cubs 8, Cincinnati Reds 3 at West Side Grounds |
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| Boston Braves 1, New York Giants 1 at Polo Grounds IV |
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| Philadelphia Phillies 8, Brooklyn Dodgers 1 at Baker Bowl |
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| St. Louis Cardinals 4, Pittsburgh Pirates 2 at Forbes Field |
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| Philadelphia Athletics 3, Boston Red Sox 2 at Huntington Ave Baseball Grounds |
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| Cleveland Indians 7, Detroit Tigers 4 at League Park II |
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| Chicago White Sox 1, St. Louis Browns 0 at Sportsman's Park III |
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| St. Louis Browns 6, Chicago White Sox 4 at Sportsman's Park III |
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| New York Yankees 8, Washington Senators 2 at American League Park II |
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| Compiled by Retrosheet (www.retrosheet.org) |
| SCOREBOARD: SEPTEMBER 10, 1910 |
| Brooklyn Dodgers 7, Philadelphia Phillies 2 at Washington Park III |
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| Brooklyn Dodgers 7, Philadelphia Phillies 1 at Washington Park III |
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| Pittsburgh Pirates 5, Chicago Cubs 4 at West Side Grounds |
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| St. Louis Cardinals 14, Cincinnati Reds 7 at Palace of the Fans |
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| New York Giants 6, Boston Braves 1 at Polo Grounds IV |
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| New York Giants 3, Boston Braves 1 at Polo Grounds IV |
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| New York Yankees 6, Boston Red Sox 3 at Huntington Ave Baseball Grounds |
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| Boston Red Sox 5, New York Yankees 3 at Huntington Ave Baseball Grounds |
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| Detroit Tigers 15, Cleveland Indians 3 at League Park II |
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| Philadelphia Athletics 3, Washington Senators 2 at Shibe Park |
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| Chicago White Sox 7, St. Louis Browns 6 at Sportsman's Park III |
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| St. Louis Browns 7, Chicago White Sox 2 at Sportsman's Park III |
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| Compiled by Retrosheet (www.retrosheet.org) |
IN THE NEWS: At Toronto, Dick Rudolph of Toronto (Eastern League) pitches 10 hitless innings over Montreal. Rudolph wins in 12 innings, 2-1.
At Oakland, Vean Gregg of Portland pitched a PCL record third 1-hitter, a 2-0 win over Oakland.
IN THE NEWS: Ty Cobb hits his 9th home run of the year, all inside the park, to clinch his only home run title.
The Giants split with the Pirates, winning 11–1, then getting outslugged, 15–3. Christy Mathewson loses the opener, allowing five runs in eight innings.
IN THE NEWS: Detroit rookie Dave Skeels, just 17-years-old, make his first and only ML appearance, surrendering eight runs, on nine hits and four walks, in six innings, but comes away with a win. He finishes the day and his ML career with an ERA of 12.00.
IN THE NEWS: Cleveland tops Washington, 3–0, with Walter Johnson losing to the Naps after four straight wins against them. The victory goes to Fred Blanding in his major league debut. Nap Lajoie scores a run but is 0-for-3.
| SCOREBOARD: SEPTEMBER 15, 1910 |
| St. Louis Cardinals 7, Boston Braves 5 at South End Grounds III |
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| St. Louis Cardinals 5, Boston Braves 1 at South End Grounds III |
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| Cincinnati Reds 7, Brooklyn Dodgers 2 at Washington Park III |
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| New York Giants 11, Pittsburgh Pirates 3 at Polo Grounds IV |
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| Pittsburgh Pirates 6, New York Giants 1 at Polo Grounds IV |
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| Chicago Cubs 7, Philadelphia Phillies 5 at Baker Bowl |
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| Chicago White Sox 4, Boston Red Sox 2 at Comiskey Park I |
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| Cleveland Indians 3, Washington Senators 0 at League Park II |
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| Philadelphia Athletics 7, Detroit Tigers 1 at Bennett Park |
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| New York Yankees 9, St. Louis Browns 3 at Sportsman's Park III |
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| Compiled by Retrosheet (www.retrosheet.org) |
IN THE NEWS: Christy Mathewson stops the Bucs on five hits, as the Giants top Pittsburgh 3–1 to move a half-game behind the 2nd place Pirates. Al Leifield takes the loss.
IN THE NEWS: Detroit pitcher Ed Summers, a notoriously poor hitter, bounces two home runs into the stands in a 10–3 victory over the A's. The two homers, both off Harry Krause, will comprise his career total.
| SCOREBOARD: SEPTEMBER 17, 1910 |
| Boston Braves 5, Pittsburgh Pirates 4 at South End Grounds III |
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| Chicago Cubs 5, Brooklyn Dodgers 3 at Washington Park III |
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| Brooklyn Dodgers 3, Chicago Cubs 2 at Washington Park III |
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| New York Giants 1, St. Louis Cardinals 0 at Polo Grounds IV |
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| New York Giants 11, St. Louis Cardinals 3 at Polo Grounds IV |
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| Cincinnati Reds 8, Philadelphia Phillies 3 at Baker Bowl |
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| Chicago White Sox 4, Boston Red Sox 3 at Comiskey Park I |
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| Cleveland Indians 7, Washington Senators 2 at League Park II |
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| Detroit Tigers 10, Philadelphia Athletics 3 at Bennett Park |
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| New York Yankees 5, St. Louis Browns 1 at Sportsman's Park III |
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| Compiled by Retrosheet (www.retrosheet.org) |
IN THE NEWS: A game between Mobile and Atlanta (Southern Association) takes just 32 minutes to complete. The game is conducted as an experiment with batters swinging at every good pitch and little time taken between pitches. There are no strikeouts and one walk as Mobile wins 2–1.
IN THE NEWS: The Cards beat the Giants, 5–1, then lose the nitecap 3–2. Rookie Ed Zmich, still looking for his first win, loses to Christy Mathewson. Matty allows 10 hits, but K's 10.
| SCOREBOARD: SEPTEMBER 20, 1910 |
| Pittsburgh Pirates 9, Boston Braves 2 at South End Grounds III |
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| Pittsburgh Pirates 7, Boston Braves 4 at South End Grounds III |
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| Chicago Cubs 5, Brooklyn Dodgers 4 at Washington Park III |
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| Chicago Cubs 3, Brooklyn Dodgers 0 at Washington Park III |
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| St. Louis Cardinals 5, New York Giants 1 at Polo Grounds IV |
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| New York Giants 3, St. Louis Cardinals 2 at Polo Grounds IV |
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| Philadelphia Phillies 2, Cincinnati Reds 0 at Baker Bowl |
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| Chicago White Sox 3, New York Yankees 0 at Comiskey Park I |
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| Philadelphia Athletics 6, Cleveland Indians 3 at League Park II |
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| Detroit Tigers 4, Washington Senators 3 at Bennett Park |
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| Detroit Tigers 6, Washington Senators 1 at Bennett Park |
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| Boston Red Sox 9, St. Louis Browns 5 at Sportsman's Park III |
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| Compiled by Retrosheet (www.retrosheet.org) |
IN THE NEWS: At Atlanta, Mobile and Atlanta break the "world's time record" for a 9-inning game, completing the match in 32 minutes. Mobile wins, 2–1. (as noted by R.J. Lesch, from The Sporting News). Both teams run in after each inning, hitters usually swing at the first pitch, though there is one walk and four stolen bases in the game.
IN THE NEWS: In the 2nd game of a DH at Cincinnati, Boston P George Ferguson hits a grand slam off Jack Rowan, in the 3rd inning, as Boston beats the Reds, 7–5. It is Ferguson's only ML homer.
IN THE NEWS: George Stallings, convinced that Hal Chase tried to throw a game, but unable to make the charge stick, is replaced by his charismatic first sacker as manager of the 2nd-place Highlanders for the season's final 11 games. On his own, Prince Hal will lead the New Yorkers downhill to 6th place in 1911.
IN THE NEWS: In another matchup of aces, the Giants score four runs in the 1st inning off Three Finger Brown, who is lifted after six innings, trailing, 5–1. The Cubs rally against Christy Mathewson, and score two runs in both the 8th and 9th innings to tie. Larry Doyle, who sloppy play helped the Cubs scoring, singles home the winning run for New York in the bottom of the 9th. Despite the Cubs tying the game after his departure, Brown is handed the loss.
| SCOREBOARD: SEPTEMBER 24, 1910 |
| Cincinnati Reds 4, Boston Braves 2 at South End Grounds III |
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| Brooklyn Dodgers 4, St. Louis Cardinals 3 at Washington Park III |
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| St. Louis Cardinals 4, Brooklyn Dodgers 2 at Washington Park III |
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| New York Giants 6, Chicago Cubs 5 at Polo Grounds IV |
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| Pittsburgh Pirates 6, Philadelphia Phillies 1 at Baker Bowl |
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| Chicago White Sox 8, Philadelphia Athletics 4 at Comiskey Park I |
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| Chicago White Sox 3, Philadelphia Athletics 2 at Comiskey Park I |
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| Boston Red Sox 8, Detroit Tigers 5 at Bennett Park |
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| Detroit Tigers 3, Boston Red Sox 2 at Bennett Park |
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| Washington Senators 6, St. Louis Browns 3 at Sportsman's Park III |
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| Compiled by Retrosheet (www.retrosheet.org) |
IN THE NEWS: In game one of a DH at Philadelphia, the Chicago White Sox stop A's ace Jack Coombs' string of shutout innings at 53 with a run in the 7th. But Coombs beats Ed Walsh 3–1 in 14 innings. The Sox win the nitecap, 5–2.
Walter Johnson tosses the first of his two career one-runner games, missing a perfect game when a grounder skips by SS George McBride for a single. Johnson's one-hitter is good for a 3–0 victory over the Browns.
| SCOREBOARD: SEPTEMBER 27, 1910 |
| Brooklyn Dodgers 4, Pittsburgh Pirates 3 at Washington Park III |
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| Cincinnati Reds 4, New York Giants 2 at Polo Grounds IV |
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| New York Giants 4, Cincinnati Reds 2 at Polo Grounds IV |
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| St. Louis Cardinals 6, Philadelphia Phillies 5 at Baker Bowl |
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| Chicago White Sox 2, Washington Senators 0 at Comiskey Park I |
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| Washington Senators 3, Chicago White Sox 2 at Comiskey Park I |
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| Cleveland Indians 5, Boston Red Sox 3 at League Park II |
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| Cleveland Indians 7, Boston Red Sox 5 at League Park II |
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| New York Yankees 10, Detroit Tigers 2 at Bennett Park |
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| Philadelphia Athletics 6, St. Louis Browns 0 at Sportsman's Park III |
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| Philadelphia Athletics 5, St. Louis Browns 4 at Sportsman's Park III |
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| Compiled by Retrosheet (www.retrosheet.org) |
| SCOREBOARD: SEPTEMBER 28, 1910 |
| Boston Braves 3, Chicago Cubs 2 at South End Grounds III |
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| Chicago Cubs 11, Boston Braves 0 at South End Grounds III |
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| Brooklyn Dodgers 2, Pittsburgh Pirates 0 at Washington Park III |
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| New York Giants 16, Cincinnati Reds 4 at Polo Grounds IV |
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| St. Louis Cardinals 5, Philadelphia Phillies 4 at Baker Bowl |
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| Washington Senators 5, Chicago White Sox 1 at Comiskey Park I |
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| Cleveland Indians 4, Boston Red Sox 3 at League Park II |
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| New York Yankees 6, Detroit Tigers 5 at Bennett Park |
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| St. Louis Browns 2, Philadelphia Athletics 1 at Sportsman's Park III |
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| Compiled by Retrosheet (www.retrosheet.org) |
IN THE NEWS: Browns 3B Ray Jansen gets four hits in five at-bats in his ML debut, the only game he will play in the majors. Speeding his exit are his three errors at the hot corner.
In a shootout at the Polo Grounds, Beals Becker hits a pinch grand slam inside-the-park as the Giants outslug Brooklyn, 17–8. It is the 2nd pinch slam IPHR in ML history; Mike O'Neill hit the first.