» August 13, 1959: The Giants and Cubs set a record for the longest 9-inning game in history, playing three hours and 50 minutes. Chicago wins the marathon at Wrigley by a score of 20–9, pounding out 19 hits and five home runs. Eddie Fisher takes the loss while Ed Donnelly is the winner.
» November 30, 1961: The Giants acquire pitchers Don Larsen and Billy Pierce from the White Sox for pitchers Eddie Fisher, Dom Zanni, and Verle Tiefenthaler and 1B Bob Farley. The swap is a steal for the Giants, one of their best trades since moving to California. Pierce, another Chicago favorite, will win 16, while Larsen will win five and save 11 for the pennant winners.
» July 28, 1962: On Old Timers Day at Yankee Stadium, White Sox knuckleballer Eddie Fisher loses a 3–0 shut out when he surrenders 7th inning homers to Mickey Mantle and Blanchard and loses, 4–3.
» October 3, 1965:
Knuckleballer Eddie Fisher of the White Sox sets an American League record with his 82nd appearance, one more than John Wyatt in 1964.
» June 13, 1966: The White Sox trade P Eddie Fisher to the Orioles for 2B Jerry Adair and OF John Riddle.
» June 24, 1968: Detroit RF Jim Northrup becomes the 6th American League player to hit two grand slams in one game, connecting in the 5th inning off Eddie Fisher and in the 6th off Billy Rohr, as the Tigers bomb Cleveland 14–3. Denny McLain is the victor. First baseman Willie Smith pitches the last three innings, walking just one and allowing one hit and no runs. Detroit's Don Wert is taken to the hospital following a 6th inning beaning which shatters his batting helmet. He will miss just a few games.
» April 17, 1973: Relief hurler Eddie Fisher, trying to become "another Wilbur Wood," beats the Rangers 10–5 in his first complete game in 10 years. It is only the 6th CG of his long career.