» June 16, 1904: The Giants score the winning run against the Cards in the bottom of the 9th when St. Louis 2B Dave Brain drops a toss for the inning-ending force. New York wins, 4-3. with the win, Christy Mathewson starts a 24-game winning streak against the Cardinals that will not end until 1908. His 33 victories and Joe McGinnity's 35 will be the most victories by two teammates since 1900. For the Giants, it is the start of an 18-game win streak.
» July 4, 1905:
The Cardinals trade INF Dave Brain to Pittsburgh for George McBride.
» August 8, 1905: Pittsburgh C Dave Brain, who hit three triples in a game for St. Louis against Pittsburgh on May 29th, repeats the performance for Pittsburgh against Boston, this time in a 10-inning game. He is the only National League player to perform the feat twice in one season.
» December 15, 1905: After losing a record 29 games this year, veteran righthander Vic Willis is traded by 7th-place Boston National League to Pittsburgh for three players: Del Howard, infielder Dave Brain, and Vive Lindaman. Willis will rebound with four straight 20-win seasons.
» June 11, 1906: At Boston, the Boston Beaneaters Dave Brain makes a ML record 5 errors at 3B, and his teammates makes another 6 to help the St. Louis Cardinals post an 8–1 win. The 11 errors ties the NL record set by the
Cardinals on April 19, 1902.
» September 16, 1907: In a doubleheader sweep, 3–1 and 3–2, of the Giants, Boston slugger Dave Brain hits his 10th homer, off the Giants Red Ames. Brain's ten round trippers will lead the NL this year, but he will never hit another. The same fate befell Fred Odwell two years ago. Brain will be sold to the Reds in May, the same route that will taken by the 1910 NL homer champion, Fred Beck.
» July 15, 1911:
The Reds swap Fred Beck, last year's co-leader in homers in the NL, to the Phils, and include Bill Burns with him. The Phils send Bert Humphries to the Reds. Beck was acquired from the Braves in March, but hit just .184 for Cincy. He was the second Brave in four years to lead the NL in homers and then get shipped to the Reds in the off-season. The other, Dave Brain, last just 16 games with the Reds in 1908.